Cardiac allograft hypertrophy: A new target for therapy, a surrogate marker for survival?

American Journal of Transplantation

Volumn 9, Issue 1, 2009, Pages 7-8

  Torre Amione, G ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETANERCEPT;

CARDIAC ALLOGRAFT HYPERTROPHY; CARDIAC ALLOGRAFT VASCULOPATHY; CLINICAL TRIAL; DISEASE MARKER; EDITORIAL; GRAFT SURVIVAL; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART TRANSPLANTATION; HEART VENTRICLE HYPERTROPHY; HUMAN; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL RATE; TREATMENT OUTCOME;

BIOLOGICAL MARKERS; CARDIOMEGALY; ELECTROCARDIOGRAPHY; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; MAGNETIC RESONANCE IMAGING; PROGNOSIS; SURVIVAL RATE; TRANSPLANTATION, HOMOLOGOUS;

EID: 58049208317     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02503.x     Document Type: Editorial

References (9)

1. Raichlin E, Villarraga HR, Chandrasekaran K et al. Cardiac allograft remodeling after heart transplantation is associated with increased graft vasculopathy and mortality. Am J Transplant 2009 9 : 132 139.
2. Goodroe R, Bonnema DD, Lunsford S et al. Severe left ventricular hypertrophy 1 year after transplant predicts mortality in cardiac transplant recipients. J Heart Lung Transplant 2007 26 : 145 151.
3. Rowan RA, Billingham ME. Pathologic changes in the long-term transplanted heart: A morphometric study of myocardial hypertrophy, vascularity, and fibrosis. Hum Pathol 1990 21 : 767 772.
4. Imakita M, Tazelaar HD, Rowan RA, Masek MA, Billingham ME. Myocyte hypertrophy in the transplanted heart. A morphometric analysis. Transplantation 1987 43 : 839 842.
5. Skrabal CA, Thompson LO, Potapov EV et al. Organ-specific regulation of pro-inflammatory molecules in heart, lung, and kidney following brain death. J Surg Res 2005 123 : 118 125.
6. Stetson SJ, Perez-Verdia A, Mazur W et al. Cardiac hypertrophy after transplantation is associated with persistent expression of tumor necrosis factor-alpha. Circulation 2001 104 : 676 681.
7. Hosenpud JD, Norman DJ, Cobanoglu MA, Floten HS, Conner RM, Starr A. Serial echocardiographic findings early after heart transplantation: Evidence for reversible right ventricular dysfunction and myocardial edema. J Heart Transplant 1987 6 : 343 347.
8. Kushwaha SS, Raichlin E, Sheinin Y et al. Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients. Eur Heart J 2008.
9. Torre-Amione G, Wallace CK, Young JB et al. The effect of etanercept on cardiac transplant recipients: A study of TNFalpha antagonism and cardiac allograft hypertrophy. Transplantation 2007 84 : 480 483.