Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer

Molecular Cancer Therapeutics

Volumn 5, Issue 5, 2006, Pages 1108-1116

  Aikawa, Takuma ^a   Gunn, Jason ^a   Spong, Suzanne M ^b   Klaus, Stephen J ^b   Korc, Murray ^a,c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b FIBROGEN INC   (United States)

^c DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CONNECTIVE TISSUE GROWTH FACTOR; FG 3019; GEMCITABINE; IMMUNOGLOBULIN G1 ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER INVASION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROSIS; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; METASTASIS INHIBITION; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS ADENOCARCINOMA; PARACRINE SIGNALING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TUMOR VASCULARIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, PANCREATIC DUCTAL; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

EID: 33745078936     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-05-0516     Document Type: Article

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