Aiming straight for the heart: Prolyl hydroxylases set the BAR

Science Signaling

Volumn 2, Issue 96, 2009, Pages

  Garcia, Joseph A ^a,b  

^a VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ACTIVATING TRANSCRIPTION FACTOR 4; ASCORBIC ACID; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; ELONGIN B; ELONGIN C; ERYTHROPOIETIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IRON; MYOGENIN; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; REACTIVE OXYGEN METABOLITE; UBIQUITIN PROTEIN LIGASE E3; VON HIPPEL LINDAU PROTEIN;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CARDIOMYOPATHY; CELL CULTURE; ENZYME ACTIVITY; GENE EXPRESSION; HEART; HEART DISEASE; HEART FAILURE; HEART INFARCTION; HEMATOCRIT; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; HYDROXYLATION; HYPOXIA; LIVER; OSTEOSARCOMA; OXIDATIVE STRESS; POLYCYTHEMIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; SKELETAL MUSCLE; UBIQUITINATION; ANIMAL; ARTICLE; ENZYMOLOGY; HEART MUSCLE; METABOLISM; MOUSE; MOUSE MUTANT;

EUKARYOTA;

ANIMALS; MICE; MICE, KNOCKOUT; MYOCARDIUM; PROCOLLAGEN-PROLINE DIOXYGENASE;

EID: 74949083520     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.296pe70     Document Type: Review

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37. The author wishes to thank the many contributors to HIF, PHD, and βAR biology, many of whose primary publications could not be cited because of space limitations. The author acknowledges funding support from the American Heart Association, Amgen, and the U.S. Department of Veterans Affairs.