-
1
-
-
0345636016
-
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells
-
Allsopp RC, Morin GB, Horner JW, DePinho R, Harley CB, Weissman IL. Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nature Medicine 2003;9:369-71.
-
(2003)
Nature Medicine
, vol.9
, pp. 369-371
-
-
Allsopp, R.C.1
Morin, G.B.2
Horner, J.W.3
DePinho, R.4
Harley, C.B.5
Weissman, I.L.6
-
2
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia -inducible factor 1α
-
An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM. Stabilization of wild-type p53 by hypoxia -inducible factor 1α. Nature 1998;392:405-8.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
3
-
-
0032411599
-
Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress
-
Amundson SA, Myers TG, Fornace AJ. Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress. Oncogene 1998;17:3287-99.
-
(1998)
Oncogene
, vol.17
, pp. 3287-3299
-
-
Amundson, S.A.1
Myers, T.G.2
Fornace, A.J.3
-
4
-
-
1542781659
-
When cells get stressed :an integrative view of cellular senescence
-
Ben-Porath IB, Weinberg RA. When cells get stressed :an integrative view of cellular senescence. J Clin Invest 2004;113:8-13.
-
(2004)
J Clin Invest
, vol.113
, pp. 8-13
-
-
Ben-Porath, I.B.1
Weinberg, R.A.2
-
5
-
-
14644410453
-
The signals and pathways activating cellular senescence
-
Ben-Porath IB, Weinberg RA. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 2005;37:961-76
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 961-976
-
-
Ben-Porath, I.B.1
Weinberg, R.A.2
-
6
-
-
31544463026
-
p53 and p66 proteins compete for Hypoxia-Inducible-Factor 1 alpha stabilization in young and old rat hearts exposed to intermittent hypoxia
-
Bianchi G, Di Giulio C, Rapino C, Rapino M, Antonucci A, Cataldi A. p53 and p66 proteins compete for Hypoxia-Inducible-Factor 1 alpha stabilization in young and old rat hearts exposed to intermittent hypoxia. Gerontology 2006;52:17-23
-
(2006)
Gerontology
, vol.52
, pp. 17-23
-
-
Bianchi, G.1
Di Giulio, C.2
Rapino, C.3
Rapino, M.4
Antonucci, A.5
Cataldi, A.6
-
7
-
-
0034597794
-
Telomere states and cell fate
-
Blackburn E. Telomere states and cell fate. Nature 2000; 408: 53-6
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.1
-
8
-
-
0035929353
-
Switching and signalling at the telomere
-
Blackburn E. Switching and signalling at the telomere. Cell 2001;106:661-73.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.1
-
9
-
-
0035165192
-
Ageing and oxidative stress: Studies of some genes involved both in ageing and in response to oxidative stress
-
Camougrand N, Rigoulet M. Ageing and oxidative stress: studies of some genes involved both in ageing and in response to oxidative stress. Respir Physiol 2001;128:393-401.
-
(2001)
Respir Physiol
, vol.128
, pp. 393-401
-
-
Camougrand, N.1
Rigoulet, M.2
-
10
-
-
0034774859
-
Cellular senescence, cancer and ageing: The telomere connection
-
Campisi J, Kim SH, Lin CS, Rubio M. Cellular senescence, cancer and ageing: the telomere connection. Exp Gerontol 2001; 36 :1619-37.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1619-1637
-
-
Campisi, J.1
Kim, S.H.2
Lin, C.S.3
Rubio, M.4
-
11
-
-
0032581277
-
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M. et al. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998;394:485-90.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
-
12
-
-
1342329226
-
Molecular and morphological modifications occurring in rat heart exposed to intermittent hypoxia: Role for Protein Kinase C α
-
Cataldi A, Bianchi G, Rapino C, Sabatini N, Centurione L, Di Giulio C., et al. Molecular and morphological modifications occurring in rat heart exposed to intermittent hypoxia: role for Protein Kinase C α. Exp Gerontol 2004; 39:395-405.
-
(2004)
Exp Gerontol
, vol.39
, pp. 395-405
-
-
Cataldi, A.1
Bianchi, G.2
Rapino, C.3
Sabatini, N.4
Centurione, L.5
Di Giulio, C.6
-
13
-
-
8844235617
-
The mitochondrial death pathway and cardiac myocyte apoptosis
-
Crow MT, Mani K, Nam YJ, Kitsis RN.The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 2004;95:957-70
-
(2004)
Circ Res
, vol.95
, pp. 957-970
-
-
Crow, M.T.1
Mani, K.2
Nam, Y.J.3
Kitsis, R.N.4
-
14
-
-
1542353401
-
Control of apoptosis by p53
-
Fridman JS, Lowe SW Control of apoptosis by p53. Oncogene 2003;22: 9030-40.
-
(2003)
Oncogene
, vol.22
, pp. 9030-9040
-
-
Fridman, J.S.1
Lowe, S.W.2
-
15
-
-
0034832956
-
Regulation of cellular senescence by p53
-
Itahana K, Dimri G, Campisi J. Regulation of cellular senescence by p53. Eur J Biochem 2001;268:2784-91.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
16
-
-
0035140981
-
Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation
-
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M., et al., Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Mol Cell Biol 2001;4:1297-310.
-
(2001)
Mol Cell Biol
, vol.4
, pp. 1297-1310
-
-
Koumenis, C.1
Alarcon, R.2
Hammond, E.3
Sutphin, P.4
Hoffman, W.5
Murphy, M.6
-
17
-
-
33644822655
-
Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: A population-base study
-
Martin-Ruiz CM, Gussekloo J, van Heemst D, von Zglinicki T, Westendorp RGJ.Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-base study. Aging Cell 2005;4:287-90.
-
(2005)
Aging Cell
, vol.4
, pp. 287-290
-
-
Martin-Ruiz, C.M.1
Gussekloo, J.2
van Heemst, D.3
von Zglinicki, T.4
Westendorp, R.G.J.5
-
19
-
-
0035964313
-
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy and survival
-
Oh H, Taffet GE, Youker KA, Entman ML, Overbeek PA, Michael LH., et al., Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy and survival. PNAS 2001;98:10308-13.
-
(2001)
PNAS
, vol.98
, pp. 10308-10313
-
-
Oh, H.1
Taffet, G.E.2
Youker, K.A.3
Entman, M.L.4
Overbeek, P.A.5
Michael, L.H.6
-
20
-
-
0036660844
-
The emerging role of telomerase in cardiac muscle cell growth and survival
-
Oh H, Schneider MD. The emerging role of telomerase in cardiac muscle cell growth and survival. J Mol Cell Cardiol 2002;34:717-24.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 717-724
-
-
Oh, H.1
Schneider, M.D.2
-
21
-
-
3042779529
-
p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment
-
Pan Y, Oprisko PR, Asham AM, Koch CJ, Simon MC. p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment . Oncogene 2004;26:4975-83.
-
(2004)
Oncogene
, vol.26
, pp. 4975-4983
-
-
Pan, Y.1
Oprisko, P.R.2
Asham, A.M.3
Koch, C.J.4
Simon, M.C.5
-
22
-
-
38049057905
-
DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection?
-
Passos JF, Saretzki G, von Zglinicki T. DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? Nucleic Acid Res 2007;35:7505-13.
-
(2007)
Nucleic Acid Res
, vol.35
, pp. 7505-7513
-
-
Passos, J.F.1
Saretzki, G.2
von Zglinicki, T.3
-
23
-
-
26944478627
-
HIF-1 alpha cytoplasmic accumulation is associated with cell death in old rat cerebral cortex exposed to intermittent hypoxia
-
Rapino C, Bianchi G, Di Giulio C, Centurione L, Cacchio M, Antonucci A, et al. HIF-1 alpha cytoplasmic accumulation is associated with cell death in old rat cerebral cortex exposed to intermittent hypoxia. Aging Cell 2005;4:177-85.
-
(2005)
Aging Cell
, vol.4
, pp. 177-185
-
-
Rapino, C.1
Bianchi, G.2
Di Giulio, C.3
Centurione, L.4
Cacchio, M.5
Antonucci, A.6
-
24
-
-
3042822263
-
Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
-
Rubio MA, Davalos AR, Campisi J. Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress. Exp Cell Res 2004;298:17-27.
-
(2004)
Exp Cell Res
, vol.298
, pp. 17-27
-
-
Rubio, M.A.1
Davalos, A.R.2
Campisi, J.3
-
25
-
-
0026006294
-
Senescence as a mode of tumour suppression
-
Sager R. Senescence as a mode of tumour suppression. Environ Health Persp 1991;93:59-62.
-
(1991)
Environ Health Persp
, vol.93
, pp. 59-62
-
-
Sager, R.1
-
26
-
-
0842334756
-
Current paradigms in cellular oxygen sensing
-
Schumacker PT. Current paradigms in cellular oxygen sensing. Adv Exp Med Biol 2003;543:57-71.
-
(2003)
Adv Exp Med Biol
, vol.543
, pp. 57-71
-
-
Schumacker, P.T.1
-
27
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza GL. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 2001;13:167-71.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
28
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 2004;19:176-82.
-
(2004)
Physiology
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
29
-
-
85047689866
-
Telomeres, stem cells, senescence and cancer
-
Sharpless NE, DePinho RA. Telomeres, stem cells, senescence and cancer. J Clin Invest 2004;113:160-8.
-
(2004)
J Clin Invest
, vol.113
, pp. 160-168
-
-
Sharpless, N.E.1
DePinho, R.A.2
-
30
-
-
0037102234
-
Different telomere damage signalling pathways in human and mouse cells
-
Smogorzewska A, de Lange T. Different telomere damage signalling pathways in human and mouse cells. EMBO J 2002;21: 4338-48
-
(2002)
EMBO J
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
de Lange, T.2
-
31
-
-
0035855668
-
De-phosphorylated HIF-1α as a mediator of p53 dependent apoptosis during hypoxia
-
Suzuki H, Tomida A, Tsurno T. De-phosphorylated HIF-1α as a mediator of p53 dependent apoptosis during hypoxia. Oncogene 2001;20:5779-88.
-
(2001)
Oncogene
, vol.20
, pp. 5779-5788
-
-
Suzuki, H.1
Tomida, A.2
Tsurno, T.3
-
32
-
-
3242715838
-
Aging of cardiac myocytes in culture. Oxidative stress, lipofuscin accumulation and mitochondrial turnover
-
Terman A, Dalen H, Eaton JW, Neuzil J, Brunk UT. Aging of cardiac myocytes in culture. Oxidative stress, lipofuscin accumulation and mitochondrial turnover. Ann N Y Acad Sci 2004;1019:70-7.
-
(2004)
Ann N Y Acad Sci
, vol.1019
, pp. 70-77
-
-
Terman, A.1
Dalen, H.2
Eaton, J.W.3
Neuzil, J.4
Brunk, U.T.5
-
33
-
-
12144291084
-
Cardiac stem cell and myocyte ageing, heart failure and insulin-like growth factor over-expression
-
Torella D, Rota M, Nurzynska D, Musso E, Monsen A, Shiraishi I., et al., Cardiac stem cell and myocyte ageing, heart failure and insulin-like growth factor over-expression. Circ Res 2004; 94: 514-24.
-
(2004)
Circ Res
, vol.94
, pp. 514-524
-
-
Torella, D.1
Rota, M.2
Nurzynska, D.3
Musso, E.4
Monsen, A.5
Shiraishi, I.6
-
34
-
-
0036629255
-
Oxidative stress shortens telomeres
-
Von Zglincki T. Oxidative stress shortens telomeres. TRENDS Biochem Sci 2002;27:339-44.
-
(2002)
TRENDS Biochem Sci
, vol.27
, pp. 339-344
-
-
Von Zglincki, T.1
-
35
-
-
27744512837
-
Telomere biology in ageing and cancer
-
Wright WE, Shay JW. Telomere biology in ageing and cancer. J Am Geriatr Soc 2005;53:S292-4.
-
(2005)
J Am Geriatr Soc
, vol.53
-
-
Wright, W.E.1
Shay, J.W.2
|