The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice

Toxicology Mechanisms and Methods

Volumn 19, Issue 9, 2009, Pages 547-551

  Kassa, Jiri ^a   Karasova, Jana Zdarova ^a   Caisberger, Filip ^b   Bajgar, Jiri ^a  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Acetylcholinesterase; HI 6; K203; Mice; Rats; Soman; Trimedoxime

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 (4 CARBAMOYLPYRIDINIUM) 4 (4 HYDROXYIMINOMETHYLPYRIDINIUM)BUT 2 ENE DIBROMIDE; ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE; K 203; OBIDOXIME; OXIME DERIVATIVE; SOMAN; TRIMEDOXIME; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME REACTIVATION; INTOXICATION; LD 50; MALE; MOUSE; MUSCLE LEVEL; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIDOTES; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DRUG COMBINATIONS; MALE; MICE; OXIMES; PYRIDINIUM COMPOUNDS; RATS; RATS, WISTAR; SOMAN; TRIMEDOXIME;

MUS; RATTUS;

EID: 74549151112     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376510903350371     Document Type: Article

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