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Volumn 175, Issue 1-3, 2008, Pages 173-179

Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning

Author keywords

Antidote; Bio scavenger; Butyrylcholinesterase; Nerve agents; Pretreatment

Indexed keywords

1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 3 (4 CARBAMOYLPYRIDINIUM); 1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 4 (4 CARBAMOYLPYRIDINIUM)BUTANE DIBROMIDE; 1,1' (BUTANE 1,4 DIYL)BIS[4 (HYDROXYLIMINOMETHYL)PYRIDINIUM]DIBROMIDE; ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE; CHOLINESTERASE; K 027; K 048; K 074; NERVE GAS; ORGANOPHOSPHORUS COMPOUND; OXIME; TABUN; TRIMEDOXIME; UNCLASSIFIED DRUG;

EID: 50649114408     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.04.011     Document Type: Article
Times cited : (34)

References (23)
  • 1
    • 0028132872 scopus 로고
    • Review of oximes available for the treatment of nerve agent poisoning
    • Dawson R.M. Review of oximes available for the treatment of nerve agent poisoning. J. Appl. Toxicol. 14 (1994) 317-331
    • (1994) J. Appl. Toxicol. , vol.14 , pp. 317-331
    • Dawson, R.M.1
  • 2
    • 33846032664 scopus 로고    scopus 로고
    • Pyridinium oximes: rationale for their selection as causal antidotes against organophosphate poisonings and current solutions for auto-injectors
    • Stoiljković M.P., and Jokanović M. Pyridinium oximes: rationale for their selection as causal antidotes against organophosphate poisonings and current solutions for auto-injectors. Arh. Hig. Rada Toksikol. 57 (2006) 435-443
    • (2006) Arh. Hig. Rada Toksikol. , vol.57 , pp. 435-443
    • Stoiljković, M.P.1    Jokanović, M.2
  • 3
    • 35349018354 scopus 로고    scopus 로고
    • Unequal efficacy of pyridinium oximes in acute organophosphate poisoning
    • Antonijević B., and Stoiljković M.P. Unequal efficacy of pyridinium oximes in acute organophosphate poisoning. Clin. Med. Res. 5 (2007) 71-82
    • (2007) Clin. Med. Res. , vol.5 , pp. 71-82
    • Antonijević, B.1    Stoiljković, M.P.2
  • 4
    • 0023615814 scopus 로고
    • Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime against tabun and soman poisoning of mice
    • Clement J.G., Shiloff J.D., and Gennings C. Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime against tabun and soman poisoning of mice. Arch. Toxicol. 61 (1987) 70-75
    • (1987) Arch. Toxicol. , vol.61 , pp. 70-75
    • Clement, J.G.1    Shiloff, J.D.2    Gennings, C.3
  • 5
    • 0027910455 scopus 로고
    • Study proves Iraq used nerve gas
    • MacIlwain C. Study proves Iraq used nerve gas. Nature 363 (1993) 3
    • (1993) Nature , vol.363 , pp. 3
    • MacIlwain, C.1
  • 7
    • 31044442395 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity
    • Čalić M., Lucić Vrdoljak A., Radić B., Jelić D., Jun D., Kuča K., and Kovarik Z. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology 219 (2006) 85-96
    • (2006) Toxicology , vol.219 , pp. 85-96
    • Čalić, M.1    Lucić Vrdoljak, A.2    Radić, B.3    Jelić, D.4    Jun, D.5    Kuča, K.6    Kovarik, Z.7
  • 9
    • 34250375666 scopus 로고    scopus 로고
    • Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-aldoximes
    • Kovarik Z., Čalić M., Šinko G., and Bosak A. Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-aldoximes. Arh. Hig. Rada Toksikol. 58 (2007) 201-209
    • (2007) Arh. Hig. Rada Toksikol. , vol.58 , pp. 201-209
    • Kovarik, Z.1    Čalić, M.2    Šinko, G.3    Bosak, A.4
  • 10
    • 47849091475 scopus 로고    scopus 로고
    • In vitro evaluation of aldoxime interactions with human acetylcholinesterase
    • Kovarik Z., Čalić M., Bosak A., Šinko G., and Jelić D. In vitro evaluation of aldoxime interactions with human acetylcholinesterase. Croat. Chem. Acta 81 (2008) 47-57
    • (2008) Croat. Chem. Acta , vol.81 , pp. 47-57
    • Kovarik, Z.1    Čalić, M.2    Bosak, A.3    Šinko, G.4    Jelić, D.5
  • 11
    • 33644811612 scopus 로고
    • New and rapid colorimetric determination of acetylcholinesterase activity
    • Ellman G.L., Courtney K.D., Andres R.M., and Featherstone. New and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7 (1961) 88-95
    • (1961) Biochem. Pharmacol. , vol.7 , pp. 88-95
    • Ellman, G.L.1    Courtney, K.D.2    Andres, R.M.3    Featherstone4
  • 12
    • 0013460414 scopus 로고    scopus 로고
    • Exploring active sites of cholinesterases by inhibition with bambuterol and haloxon
    • Kovarik Z., Bosak A., Šinko G., and Latas T. Exploring active sites of cholinesterases by inhibition with bambuterol and haloxon. Croat. Chem. Acta. 76 (2003) 63-67
    • (2003) Croat. Chem. Acta. , vol.76 , pp. 63-67
    • Kovarik, Z.1    Bosak, A.2    Šinko, G.3    Latas, T.4
  • 13
    • 28744455820 scopus 로고    scopus 로고
    • Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups
    • Šinko G., Bosak A., Kovarik Z., and Simeon-Rudolf V. Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups. Chem. -Biol. Interact. 157-158 (2005) 421-423
    • (2005) Chem. -Biol. Interact. , vol.157-158 , pp. 421-423
    • Šinko, G.1    Bosak, A.2    Kovarik, Z.3    Simeon-Rudolf, V.4
  • 14
    • 33646545038 scopus 로고    scopus 로고
    • para- and ortho-Pyridinium aldoximes in reaction with acetylthiocholine
    • Šinko G., Čalić M., and Kovarik Z. para- and ortho-Pyridinium aldoximes in reaction with acetylthiocholine. FEBS Lett. 580 (2006) 3167-3172
    • (2006) FEBS Lett. , vol.580 , pp. 3167-3172
    • Šinko, G.1    Čalić, M.2    Kovarik, Z.3
  • 15
    • 34748879427 scopus 로고    scopus 로고
    • Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes
    • Šinko G., Čalić M., Bosak A., and Kovarik Z. Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes. Anal. Biochem. 370 (2007) 223-227
    • (2007) Anal. Biochem. , vol.370 , pp. 223-227
    • Šinko, G.1    Čalić, M.2    Bosak, A.3    Kovarik, Z.4
  • 16
    • 0345135891 scopus 로고
    • Inhibition of acetylcholinesterase by 4,4′-bipyridine and its effect upon phosphylation of the enzyme
    • Reiner E. Inhibition of acetylcholinesterase by 4,4′-bipyridine and its effect upon phosphylation of the enzyme. Croat. Chem. Acta 59 (1986) 925-931
    • (1986) Croat. Chem. Acta , vol.59 , pp. 925-931
    • Reiner, E.1
  • 17
    • 84957354361 scopus 로고
    • Use of moving averages and interpolation to estimate median-effective dose
    • Thompson W.R. Use of moving averages and interpolation to estimate median-effective dose. Bacteriol. Rev. 11 (1947) 115-145
    • (1947) Bacteriol. Rev. , vol.11 , pp. 115-145
    • Thompson, W.R.1
  • 18
    • 0001617649 scopus 로고
    • Tables for convenient calculation of median-effective dose (LD50 or ED50) and instruction in their use
    • Weil C.S. Tables for convenient calculation of median-effective dose (LD50 or ED50) and instruction in their use. Biometrics 8 (1952) 249-263
    • (1952) Biometrics , vol.8 , pp. 249-263
    • Weil, C.S.1
  • 20
    • 0037756828 scopus 로고    scopus 로고
    • Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators
    • Ashani Y., Bhattacharjee A.K., Leader H., Saxena A., and Doctor B.P. Inhibition of cholinesterases with cationic phosphonyl oximes highlights distinctive properties of the charged pyridine groups of quaternary oxime reactivators. Biochem. Pharmacol. 66 (2003) 191-202
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 191-202
    • Ashani, Y.1    Bhattacharjee, A.K.2    Leader, H.3    Saxena, A.4    Doctor, B.P.5
  • 21
    • 1542533645 scopus 로고    scopus 로고
    • Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates
    • Kovarik Z., Radić Z., Berman H.A., Simeon-Rudolf V., Reiner E., and Taylor P. Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates. Biochemistry 43 (2004) 3222-3229
    • (2004) Biochemistry , vol.43 , pp. 3222-3229
    • Kovarik, Z.1    Radić, Z.2    Berman, H.A.3    Simeon-Rudolf, V.4    Reiner, E.5    Taylor, P.6
  • 23
    • 33947678881 scopus 로고    scopus 로고
    • Evaluation of newly synthesized monoquaternary pyridinium oximes potency to reactivate tabun-phosphorylated acetylcholinesterase
    • Odžak R., Čalić M., Hrenar T., Primožič I., and Kovarik Z. Evaluation of newly synthesized monoquaternary pyridinium oximes potency to reactivate tabun-phosphorylated acetylcholinesterase. Toxicology 233 (2007) 85-96
    • (2007) Toxicology , vol.233 , pp. 85-96
    • Odžak, R.1    Čalić, M.2    Hrenar, T.3    Primožič, I.4    Kovarik, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.