Development of antidotes: Problems and strategies

Toxicology

Volumn 233, Issue 1-3 SPEC. ISS., 2007, Pages 23-30

  Szinicz, Ladislaus ^a   Worek, Franz ^a   Thiermann, Horst ^a   Kehe, Kai ^a   Eckert, Saskia ^a,b   Eyer, Peter ^b  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antidotes; Chemical agents; Development strategies; Organophosphates; Sulfur mustard

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE; CHEMICAL WARFARE AGENT; CHOLINESTERASE INHIBITOR; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; MUSTARD GAS; NERVE GAS; OBIDOXIME; OXIME DERIVATIVE; PARAOXON; PESTICIDE; PHYSOSTIGMINE; PRALIDOXIME;

ARTICLE; CHEMICAL WARFARE; CORRELATION ANALYSIS; DIAPHRAGM; DISEASE MODEL; DRUG EFFICACY; DRUG RESEARCH; ERYTHROCYTE; HUMAN; INTOXICATION; LD 50; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR FUNCTION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RESEARCH PRIORITY; SKIN CULTURE;

ANIMALS; ANTIDOTES; BIOMEDICAL RESEARCH; CHEMICAL WARFARE; CHEMICAL WARFARE AGENTS; DRUG INDUSTRY; HUMANS; ORGANOPHOSPHORUS COMPOUNDS;

ANIMALIA;

EID: 33947651286     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.07.008     Document Type: Article

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