메뉴 건너뛰기




Volumn 24, Issue 12, 2009, Pages 2039-2049

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men

(16)  Yerges, Laura M a   Klei, Lambertus b   Cauley, Jane A a   Roeder, Kathryn c   Kammerer, Candace M d   Moffett, Susan P a   Ensrud, Kristine E e   Nestlerode, Cara S a   Marshall, Lynn M f   Hoffman, Andrew R g   Lewis, Cora h   Lang, Thomas F i   Barrett Connor, Elizabeth j   Ferrell, Robert E d   Orwoll, Eric S f   Zmuda, Joseph M a,d  


Author keywords

BMD; Genetics; Men; Osteoporosis; QCT

Indexed keywords

ADULT; AGED; APC GENE; ARTICLE; BMPR1B GENE; BONE DENSITY; COMMUNITY LIVING; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DMP1 GENE; FEMUR NECK; FGFR2 GENE; FLT1 GENE; FOXC2 GENE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HOXA GENE; HUMAN; IGFBP2 GENE; LUMBAR SPINE; MALE; NFATC1 GENE; PTN GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SOST GENE;

EID: 73849131430     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.090524     Document Type: Article
Times cited : (55)

References (75)
  • 1
    • 0028799124 scopus 로고
    • The worldwide problem of osteoporosis: Insights afforded by epidemiology
    • Riggs BL, Melton LJ III 1995 The worldwide problem of osteoporosis: Insights afforded by epidemiology. Bone 17(Suppl):505S-511S.
    • (1995) Bone , vol.17 , Issue.SUPPL.
    • Riggs, B.L.1    Melton III, L.J.2
  • 2
    • 22344457145 scopus 로고    scopus 로고
    • Quality-of-life issues in osteoporosis
    • Silverman SL 2005 Quality-of-life issues in osteoporosis. Curr Rheumatol Rep 7:39-45.
    • (2005) Curr Rheumatol Rep , vol.7 , pp. 39-45
    • Silverman, S.L.1
  • 3
    • 0035857351 scopus 로고    scopus 로고
    • Osteoporosis prevention, diagnosis, and therapy
    • Anonymous
    • Anonymous 2001 Osteoporosis prevention, diagnosis, and therapy. JAMA 285:785-795.
    • (2001) JAMA , vol.285 , pp. 785-795
  • 4
    • 33748680524 scopus 로고    scopus 로고
    • Genetic regulation of bone mass and susceptibility to osteoporosis
    • Ralston SH, de Crombrugghe B 2006 Genetic regulation of bone mass and susceptibility to osteoporosis. Genes Dev 20:2492-2506.
    • (2006) Genes Dev , vol.20 , pp. 2492-2506
    • Ralston, S.H.1    de Crombrugghe, B.2
  • 5
    • 0033810015 scopus 로고    scopus 로고
    • Associations between maternal peak bone mass and bone mass in prepubertal male and female children
    • Jones G, Nguyen TV 2000 Associations between maternal peak bone mass and bone mass in prepubertal male and female children. J Bone Miner Res 15:1998-2004.
    • (2000) J Bone Miner Res , vol.15 , pp. 1998-2004
    • Jones, G.1    Nguyen, T.V.2
  • 7
    • 44349167229 scopus 로고    scopus 로고
    • Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, Jonsdottir T, Saemundsdottir J, Center JR, Nguyen TV, Bagger Y, Gulcher JR, Eisman JA, Christiansen C, Sigurdsson G, Kong A, Thorsteinsdottir U, Stefansson K 2008 Multiple genetic loci for bone mineral density and fractures. N Engl J Med 358:2355-2365.
    • Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, Jonsdottir T, Saemundsdottir J, Center JR, Nguyen TV, Bagger Y, Gulcher JR, Eisman JA, Christiansen C, Sigurdsson G, Kong A, Thorsteinsdottir U, Stefansson K 2008 Multiple genetic loci for bone mineral density and fractures. N Engl J Med 358:2355-2365.
  • 8
    • 43049157833 scopus 로고    scopus 로고
    • Snipping away at osteoporosis susceptibility
    • Zmuda JM, Kammerer CM 2008 Snipping away at osteoporosis susceptibility. Lancet 371:1479-1480.
    • (2008) Lancet , vol.371 , pp. 1479-1480
    • Zmuda, J.M.1    Kammerer, C.M.2
  • 9
    • 0026586120 scopus 로고
    • New approaches for interpreting projected bone densitometry data
    • Carter DR, Bouxsein ML, Marcus R 1992 New approaches for interpreting projected bone densitometry data. J Bone Miner Res 7:137-145.
    • (1992) J Bone Miner Res , vol.7 , pp. 137-145
    • Carter, D.R.1    Bouxsein, M.L.2    Marcus, R.3
  • 10
    • 0025900456 scopus 로고
    • The influence of osteophytes and aortic calcification on spinal mineral density in postmenopausal women
    • Reid IR, Evans MC, Ames R, Wattie DJ 1991 The influence of osteophytes and aortic calcification on spinal mineral density in postmenopausal women. J Clin Endocrinol Metab 72:1372-1374.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1372-1374
    • Reid, I.R.1    Evans, M.C.2    Ames, R.3    Wattie, D.J.4
  • 11
    • 0029033292 scopus 로고
    • Influence of degenerative joint disease on spinal bone mineral measurements in postmenopausal women
    • Yu W, Gluer CC, Fuerst T, Grampp S, Li J, Lu Y, Genant HK 1995 Influence of degenerative joint disease on spinal bone mineral measurements in postmenopausal women. Calcif Tissue Int 57:169-174.
    • (1995) Calcif Tissue Int , vol.57 , pp. 169-174
    • Yu, W.1    Gluer, C.C.2    Fuerst, T.3    Grampp, S.4    Li, J.5    Lu, Y.6    Genant, H.K.7
  • 12
    • 0031439464 scopus 로고    scopus 로고
    • Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women
    • Liu G, Peacock M, Eilam O, Dorulla G, Braunstein E, Johnston CC 1997 Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women. Osteoporos Int 7:564-569.
    • (1997) Osteoporos Int , vol.7 , pp. 564-569
    • Liu, G.1    Peacock, M.2    Eilam, O.3    Dorulla, G.4    Braunstein, E.5    Johnston, C.C.6
  • 13
    • 0025273271 scopus 로고
    • The impact of osteophytic and vascular calcifications on vertebral mineral density measurements in men
    • Orwoll ES, Oviatt SK, Mann T 1990 The impact of osteophytic and vascular calcifications on vertebral mineral density measurements in men. J Clin Endocrinol Metab 70:1202-1207.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1202-1207
    • Orwoll, E.S.1    Oviatt, S.K.2    Mann, T.3
  • 15
    • 24144494819 scopus 로고    scopus 로고
    • Blank JB, Cawthon PM, Carrion-Petersen ML, Harper L, Johnson JP, Mitson E, Delay RR 2005 Overview of recruitment for the osteoporotic fractures in men study (MrOS). Contemp Clin Trials 26:557-568.
    • Blank JB, Cawthon PM, Carrion-Petersen ML, Harper L, Johnson JP, Mitson E, Delay RR 2005 Overview of recruitment for the osteoporotic fractures in men study (MrOS). Contemp Clin Trials 26:557-568.
  • 16
  • 17
    • 79959503826 scopus 로고    scopus 로고
    • International HapMap Consortium 2003 The International HapMap Project. Nature 426:789-796.
    • International HapMap Consortium 2003 The International HapMap Project. Nature 426:789-796.
  • 18
  • 19
    • 2642529617 scopus 로고    scopus 로고
    • Promo-Lign: A database for upstream region analysis and SNPs
    • Zhao T, Chang LW, McLeod HL, Stormo GD 2004 Promo-Lign: A database for upstream region analysis and SNPs. Hum Mutat 23:534-539.
    • (2004) Hum Mutat , vol.23 , pp. 534-539
    • Zhao, T.1    Chang, L.W.2    McLeod, H.L.3    Stormo, G.D.4
  • 21
    • 0035257236 scopus 로고    scopus 로고
    • Association study designs for complex diseases
    • Cardon LR, Bell JI 2001 Association study designs for complex diseases. Nat Rev Genet 2:91-99.
    • (2001) Nat Rev Genet , vol.2 , pp. 91-99
    • Cardon, L.R.1    Bell, J.I.2
  • 22
    • 0041817568 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
    • Falush D, Stephens M, Pritchard JK 2003 Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies. Genetics 164:1567-1587.
    • (2003) Genetics , vol.164 , pp. 1567-1587
    • Falush, D.1    Stephens, M.2    Pritchard, J.K.3
  • 24
    • 34447525510 scopus 로고    scopus 로고
    • Effects of genes, sex, age, and activity on BMC, bone size, and areal and volumetric BMD
    • Havill LM, Mahaney MC, Binkley TL, Specker BL 2007 Effects of genes, sex, age, and activity on BMC, bone size, and areal and volumetric BMD. J Bone Miner Res 22:737-746.
    • (2007) J Bone Miner Res , vol.22 , pp. 737-746
    • Havill, L.M.1    Mahaney, M.C.2    Binkley, T.L.3    Specker, B.L.4
  • 25
    • 34249677477 scopus 로고    scopus 로고
    • Genetic and environmental determinants of volumetric and areal BMD in multi-generational families of African ancestry: The Tobago Family Health Study
    • Wang X, Kammerer CM, Wheeler VW, Patrick AL, Bunker CH, Zmuda JM 2007 Genetic and environmental determinants of volumetric and areal BMD in multi-generational families of African ancestry: The Tobago Family Health Study. J Bone Miner Res 22:527-536.
    • (2007) J Bone Miner Res , vol.22 , pp. 527-536
    • Wang, X.1    Kammerer, C.M.2    Wheeler, V.W.3    Patrick, A.L.4    Bunker, C.H.5    Zmuda, J.M.6
  • 26
    • 33748168883 scopus 로고    scopus 로고
    • Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals
    • Yamada Y, Ando F, Shimokata H 2006 Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals. Int J Mol Med 18:119-127.
    • (2006) Int J Mol Med , vol.18 , pp. 119-127
    • Yamada, Y.1    Ando, F.2    Shimokata, H.3
  • 31
    • 0028987249 scopus 로고
    • Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
    • Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P 1995 Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 92:3046-3050.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3046-3050
    • Munemitsu, S.1    Albert, I.2    Souza, B.3    Rubinfeld, B.4    Polakis, P.5
  • 32
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • Westendorf JJ, Kahler RA, Schroeder TM 2004 Wnt signaling in osteoblasts and bone diseases. Gene 341:19-39.
    • (2004) Gene , vol.341 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 33
    • 0035663742 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC), beta-catenin, and cadherin are expressed in human bone and cartilage
    • Monaghan H, Bubb VJ, Sirimujalin R, Millward-Sadler SJ, Salter DM 2001 Adenomatous polyposis coli (APC), beta-catenin, and cadherin are expressed in human bone and cartilage. Histopathology 39:611-619.
    • (2001) Histopathology , vol.39 , pp. 611-619
    • Monaghan, H.1    Bubb, V.J.2    Sirimujalin, R.3    Millward-Sadler, S.J.4    Salter, D.M.5
  • 35
    • 0030111426 scopus 로고    scopus 로고
    • Sticky fingers: Hox genes and cell adhesion in vertebrate limb development
    • Newman SA 1996 Sticky fingers: Hox genes and cell adhesion in vertebrate limb development. Bioessays 18:171-174.
    • (1996) Bioessays , vol.18 , pp. 171-174
    • Newman, S.A.1
  • 38
    • 28144464147 scopus 로고    scopus 로고
    • DMP1 depletion decreases bone mineralization in vivo: An FTIR imaging analysis
    • Ling Y, Rios HF, Myers ER, Lu Y, Feng JQ, Boskey AL 2005 DMP1 depletion decreases bone mineralization in vivo: An FTIR imaging analysis. J Bone Miner Res 20:2169-2177.
    • (2005) J Bone Miner Res , vol.20 , pp. 2169-2177
    • Ling, Y.1    Rios, H.F.2    Myers, E.R.3    Lu, Y.4    Feng, J.Q.5    Boskey, A.L.6
  • 40
    • 37549059576 scopus 로고    scopus 로고
    • Dentin matrix protein 1 (DMP1): New and important roles for biomineralization and phosphate homeostasis
    • Qin C, D'Souza R, Feng JQ 2007 Dentin matrix protein 1 (DMP1): New and important roles for biomineralization and phosphate homeostasis. J Dent Res 86:1134-1141.
    • (2007) J Dent Res , vol.86 , pp. 1134-1141
    • Qin, C.1    D'Souza, R.2    Feng, J.Q.3
  • 43
    • 47249127690 scopus 로고    scopus 로고
    • A close examination of genes within quantitative trait loci of bone mineral density in whole mouse genome
    • Xiong Q, Han C, Beamer WG, Gu W 2008 A close examination of genes within quantitative trait loci of bone mineral density in whole mouse genome. Crit Rev Eukaryot Gene Expr 18:323-343.
    • (2008) Crit Rev Eukaryot Gene Expr , vol.18 , pp. 323-343
    • Xiong, Q.1    Han, C.2    Beamer, W.G.3    Gu, W.4
  • 44
    • 17844402791 scopus 로고    scopus 로고
    • Bad bones, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations
    • Wilkie AO 2005 Bad bones, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations. Cytokine Growth Factor Rev 16:187-203.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 187-203
    • Wilkie, A.O.1
  • 45
    • 0037238162 scopus 로고    scopus 로고
    • Activating (P253R, C278F) and dominant negative mutations of FGFR2: Differential effects on calvarial bone cell proliferation, differentiation, and mineralization
    • Ratisoontorn C, Fan GF, McEntee K, Nah HD 2003 Activating (P253R, C278F) and dominant negative mutations of FGFR2: Differential effects on calvarial bone cell proliferation, differentiation, and mineralization. Connect Tissue Res 44(Suppl 1):292-297.
    • (2003) Connect Tissue Res , vol.44 , Issue.SUPPL. 1 , pp. 292-297
    • Ratisoontorn, C.1    Fan, G.F.2    McEntee, K.3    Nah, H.D.4
  • 46
    • 0036604082 scopus 로고    scopus 로고
    • Possible involvement of the vascular endothelial growth factor-Flt-1-focal adhesion kinase pathway in chemotaxis and the cell proliferation of osteoclast precursor cells in arthritic joints
    • Matsumoto Y, Tanaka K, Hirata G, Hanada M, Matsuda S, Shuto T, Iwamoto Y 2002 Possible involvement of the vascular endothelial growth factor-Flt-1-focal adhesion kinase pathway in chemotaxis and the cell proliferation of osteoclast precursor cells in arthritic joints. J Immunol 168:5824-5831.
    • (2002) J Immunol , vol.168 , pp. 5824-5831
    • Matsumoto, Y.1    Tanaka, K.2    Hirata, G.3    Hanada, M.4    Matsuda, S.5    Shuto, T.6    Iwamoto, Y.7
  • 47
    • 0034640211 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts
    • Nakagawa M, Kaneda T, Arakawa T, Morita S, Sato T, Yomada T, Hanada K, Kumegawa M, Hakeda Y 2000 Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts. FEBS Lett 473:161-164.
    • (2000) FEBS Lett , vol.473 , pp. 161-164
    • Nakagawa, M.1    Kaneda, T.2    Arakawa, T.3    Morita, S.4    Sato, T.5    Yomada, T.6    Hanada, K.7    Kumegawa, M.8    Hakeda, Y.9
  • 48
    • 0033584243 scopus 로고    scopus 로고
    • Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption
    • Niida S, Kaku M, Amano H, Yoshida H, Kataoka H, Nishikawa S, Tanne K, Maeda N, Kodama H 1999 Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J Exp Med 190:293-298.
    • (1999) J Exp Med , vol.190 , pp. 293-298
    • Niida, S.1    Kaku, M.2    Amano, H.3    Yoshida, H.4    Kataoka, H.5    Nishikawa, S.6    Tanne, K.7    Maeda, N.8    Kodama, H.9
  • 49
    • 33746082072 scopus 로고    scopus 로고
    • Association between UHMWPE particle-induced inflammatory osteoclastogenesis and expression of RANKL, VEGF, and Flt-1 in vivo
    • Ren WP, Markel DC, Zhang R, Peng X, Wu B, Monica H, Wooley PH 2006 Association between UHMWPE particle-induced inflammatory osteoclastogenesis and expression of RANKL, VEGF, and Flt-1 in vivo. Biomaterials 27:5161-5169.
    • (2006) Biomaterials , vol.27 , pp. 5161-5169
    • Ren, W.P.1    Markel, D.C.2    Zhang, R.3    Peng, X.4    Wu, B.5    Monica, H.6    Wooley, P.H.7
  • 51
    • 34248512083 scopus 로고    scopus 로고
    • Flt-1 tyrosine kinase-deficient homozygous mice result in decreased trabecular bone volume with reduced osteogenic potential
    • Otomo H, Sakai A, Uchida S, Tanaka S, Watanuki M, Moriwaki S, Niida S, Nakamura T 2007 Flt-1 tyrosine kinase-deficient homozygous mice result in decreased trabecular bone volume with reduced osteogenic potential. Bone 40:1494-1501.
    • (2007) Bone , vol.40 , pp. 1494-1501
    • Otomo, H.1    Sakai, A.2    Uchida, S.3    Tanaka, S.4    Watanuki, M.5    Moriwaki, S.6    Niida, S.7    Nakamura, T.8
  • 52
    • 0037215657 scopus 로고    scopus 로고
    • Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/ pleiotrophin: Osteoconductive biomimetic scaffolds for tissue engineering
    • Yang X, Tare RS, Partridge KA, Roach HI, Clarke NM, Howdle SM, Shakesheff KM, Oreffo RO 2003 Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/ pleiotrophin: Osteoconductive biomimetic scaffolds for tissue engineering. J Bone Miner Res 18:47-57.
    • (2003) J Bone Miner Res , vol.18 , pp. 47-57
    • Yang, X.1    Tare, R.S.2    Partridge, K.A.3    Roach, H.I.4    Clarke, N.M.5    Howdle, S.M.6    Shakesheff, K.M.7    Oreffo, R.O.8
  • 53
    • 0036830216 scopus 로고    scopus 로고
    • Pleiotrophin/ Osteoblast-stimulating factor 1: Dissecting its diverse functions in bone formation
    • Tare RS, Oreffo RO, Clarke NM, Roach HI 2002 Pleiotrophin/ Osteoblast-stimulating factor 1: Dissecting its diverse functions in bone formation. J Bone Miner Res 17:2009-2020.
    • (2002) J Bone Miner Res , vol.17 , pp. 2009-2020
    • Tare, R.S.1    Oreffo, R.O.2    Clarke, N.M.3    Roach, H.I.4
  • 55
    • 0037054548 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation
    • Zhao M, Harris SE, Horn D, Geng Z, Nishimura R, Mundy GR, Chen D 2002 Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation. J Cell Biol 157:1049-1060.
    • (2002) J Cell Biol , vol.157 , pp. 1049-1060
    • Zhao, M.1    Harris, S.E.2    Horn, D.3    Geng, Z.4    Nishimura, R.5    Mundy, G.R.6    Chen, D.7
  • 57
    • 0034803019 scopus 로고    scopus 로고
    • Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells
    • Nifuji A, Miura N, Kato N, Kellermann O, Noda M 2001 Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells. J Bone Miner Res 16:1765-1771.
    • (2001) J Bone Miner Res , vol.16 , pp. 1765-1771
    • Nifuji, A.1    Miura, N.2    Kato, N.3    Kellermann, O.4    Noda, M.5
  • 58
    • 28844506375 scopus 로고    scopus 로고
    • Role of IGFBP2, IGF-I and IGF-II in regulating long bone growth
    • Fisher MC, Meyer C, Garber G, Dealy CN 2005 Role of IGFBP2, IGF-I and IGF-II in regulating long bone growth. Bone 37:741-750.
    • (2005) Bone , vol.37 , pp. 741-750
    • Fisher, M.C.1    Meyer, C.2    Garber, G.3    Dealy, C.N.4
  • 59
    • 0036592185 scopus 로고    scopus 로고
    • Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis
    • Conover CA, Johnstone EW, Turner RT, Evans GL, John Ballard FJ, Doran PM, Khosla S 2002 Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis. Growth Horm IGF Res 12:178-183.
    • (2002) Growth Horm IGF Res , vol.12 , pp. 178-183
    • Conover, C.A.1    Johnstone, E.W.2    Turner, R.T.3    Evans, G.L.4    John Ballard, F.J.5    Doran, P.M.6    Khosla, S.7
  • 61
    • 0030741644 scopus 로고    scopus 로고
    • Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures
    • Sugimoto T, Nishiyama K, Kuribayashi F, Chihara K 1997 Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures. J Bone Miner Res 12:1272-1279.
    • (1997) J Bone Miner Res , vol.12 , pp. 1272-1279
    • Sugimoto, T.1    Nishiyama, K.2    Kuribayashi, F.3    Chihara, K.4
  • 63
    • 33749025045 scopus 로고    scopus 로고
    • The calcineurin-NFAT pathway and bone: Intriguing new findings
    • Stern PH 2006 The calcineurin-NFAT pathway and bone: Intriguing new findings. Mol Interv 6:193-196.
    • (2006) Mol Interv , vol.6 , pp. 193-196
    • Stern, P.H.1
  • 67
    • 41149101588 scopus 로고    scopus 로고
    • Genetic flip-flop without an accompanying change in linkage disequilibrium
    • Zaykin DV, Shibata K 2008 Genetic flip-flop without an accompanying change in linkage disequilibrium. Am J Hum Genet 82:794-796.
    • (2008) Am J Hum Genet , vol.82 , pp. 794-796
    • Zaykin, D.V.1    Shibata, K.2
  • 68
    • 0034744673 scopus 로고    scopus 로고
    • A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men
    • Zmuda JM, Cauley JA, Kuller LH, Ferrell RE 2001 A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men. J Bone Miner Res 16:911-917.
    • (2001) J Bone Miner Res , vol.16 , pp. 911-917
    • Zmuda, J.M.1    Cauley, J.A.2    Kuller, L.H.3    Ferrell, R.E.4
  • 69
    • 4444384645 scopus 로고    scopus 로고
    • Two single nucleotide polymorphisms in the CYP17 and COMT Genes - relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy. The Danish Osteoporosis Prevention Study
    • Tofteng CL, Abrahamsen B, Jensen JE, Petersen S, Teilmann J, Kindmark A, Vestergaard P, Gram J, Langdahl BL, Mosekilde L 2004 Two single nucleotide polymorphisms in the CYP17 and COMT Genes - relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy. The Danish Osteoporosis Prevention Study. Calcif Tissue Int 75:123-132.
    • (2004) Calcif Tissue Int , vol.75 , pp. 123-132
    • Tofteng, C.L.1    Abrahamsen, B.2    Jensen, J.E.3    Petersen, S.4    Teilmann, J.5    Kindmark, A.6    Vestergaard, P.7    Gram, J.8    Langdahl, B.L.9    Mosekilde, L.10
  • 70
    • 20444423769 scopus 로고    scopus 로고
    • Association of polymorphisms in CYP17A1, MTP, and VLDLR with bone mineral density in community-dwelling Japanese women and men
    • Yamada Y, Ando F, Shimokata H 2005 Association of polymorphisms in CYP17A1, MTP, and VLDLR with bone mineral density in community-dwelling Japanese women and men. Genomics 86:76-85.
    • (2005) Genomics , vol.86 , pp. 76-85
    • Yamada, Y.1    Ando, F.2    Shimokata, H.3
  • 71
    • 24644453609 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha, CYP 17, urokinase, and interleukin 10 gene polymorphisms in postmenopausal women: Correlation to bone mineral density and susceptibility to osteoporosis
    • Chen HY, Chen WC, Hsu CM, Tsai FJ, Tsai CH 2005 Tumor necrosis factor alpha, CYP 17, urokinase, and interleukin 10 gene polymorphisms in postmenopausal women: Correlation to bone mineral density and susceptibility to osteoporosis. Eur J Obstet Gynecol Reprod Biol 122:73-78.
    • (2005) Eur J Obstet Gynecol Reprod Biol , vol.122 , pp. 73-78
    • Chen, H.Y.1    Chen, W.C.2    Hsu, C.M.3    Tsai, F.J.4    Tsai, C.H.5
  • 74
    • 40949146531 scopus 로고    scopus 로고
    • van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellstrom D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG 2008 Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 299:1277-1290.
    • van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellstrom D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG 2008 Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 299:1277-1290.
  • 75
    • 42649139571 scopus 로고    scopus 로고
    • Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JR, Stevens S, Hall AS, Samani NJ, Shields B, Prokopenko I, Farrall M, Dominiczak A, Johnson T, Bergmann S, Beckmann JS, Vollenweider P, Waterworth DM, Mooser V, Palmer CN, Morris AD, Ouwehand WH, Zhao JH, Li S, Loos RJ, Barroso I, Deloukas P, Sandhu MS, Wheeler E, Soranzo N, Inouye M, Wareham NJ, Caulfield M, Munroe PB, Hattersley AT, McCarthy MI, Frayling TM 2008 Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 40:575-583.
    • Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JR, Stevens S, Hall AS, Samani NJ, Shields B, Prokopenko I, Farrall M, Dominiczak A, Johnson T, Bergmann S, Beckmann JS, Vollenweider P, Waterworth DM, Mooser V, Palmer CN, Morris AD, Ouwehand WH, Zhao JH, Li S, Loos RJ, Barroso I, Deloukas P, Sandhu MS, Wheeler E, Soranzo N, Inouye M, Wareham NJ, Caulfield M, Munroe PB, Hattersley AT, McCarthy MI, Frayling TM 2008 Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 40:575-583.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.