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Volumn 268, Issue 1-2, 2010, Pages 55-63

Comparative pharmacokinetics of chlorpyrifos versus its major metabolites following oral administration in the rat

Author keywords

Chlorpyrifos; Diethylthiophosphate; Pharmacokinetics; Trichloropyridinol

Indexed keywords

2 HYDROXY 3,5,6 TRICHLORPYRIDINE; CARBON 13; CHLORPYRIFOS; DEUTERIUM; DIETHYLTHIOPHOSPHATE; INSECTICIDE; PESTICIDE; UNCLASSIFIED DRUG;

EID: 73749085788     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.11.022     Document Type: Article
Times cited : (22)

References (57)
  • 1
    • 0028594076 scopus 로고
    • Biological monitoring of exposure to organophosphorus insecticides by assay of urinary alkylphosphates-influence of protective measures during manual operations with treated plants
    • Aprea C., Sciarra G., Sartorelli P., Desideri E., Amati R., and Sartorelli E. Biological monitoring of exposure to organophosphorus insecticides by assay of urinary alkylphosphates-influence of protective measures during manual operations with treated plants. International Archives of Occupational and Environmental Health 66 (1994) 333-338
    • (1994) International Archives of Occupational and Environmental Health , vol.66 , pp. 333-338
    • Aprea, C.1    Sciarra, G.2    Sartorelli, P.3    Desideri, E.4    Amati, R.5    Sartorelli, E.6
  • 5
    • 0019580182 scopus 로고
    • The use of stable isotopes in pharmacological research
    • Baillie T.A. The use of stable isotopes in pharmacological research. Pharmacological Reviews 33 (1981) 81-132
    • (1981) Pharmacological Reviews , vol.33 , pp. 81-132
    • Baillie, T.A.1
  • 6
    • 0017100949 scopus 로고
    • Rat urinary metabolites from O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl) phosphorothioate
    • Bakke J.E., Feil V.J., and Price C.E. Rat urinary metabolites from O,O-diethyl-O-(3,5,6-trichloro-2-pyridyl) phosphorothioate. Journal of Environmental Science Health B 11 (1976) 225-230
    • (1976) Journal of Environmental Science Health B , vol.11 , pp. 225-230
    • Bakke, J.E.1    Feil, V.J.2    Price, C.E.3
  • 7
    • 33750854365 scopus 로고    scopus 로고
    • Potential uses of biomonitoring data: a case study using the organophosphorus pesticides chlorpyrifos and malathion
    • Barr D.B., and Angerer J. Potential uses of biomonitoring data: a case study using the organophosphorus pesticides chlorpyrifos and malathion. Environmental Health Perspectives 114 (2006) 1763-1769
    • (2006) Environmental Health Perspectives , vol.114 , pp. 1763-1769
    • Barr, D.B.1    Angerer, J.2
  • 8
    • 0037027019 scopus 로고    scopus 로고
    • Analytical methods for biological monitoring of exposure to pesticides: a review
    • Barr D.B., and Needham L.L. Analytical methods for biological monitoring of exposure to pesticides: a review. Journal of Chromatography B 778 (2002) 5-29
    • (2002) Journal of Chromatography B , vol.778 , pp. 5-29
    • Barr, D.B.1    Needham, L.L.2
  • 12
    • 0017193301 scopus 로고
    • Improved method for determination of urinary dimethyl-phosphate
    • Blair D., and Roderick H.R. Improved method for determination of urinary dimethyl-phosphate. Journal of Agricultral Food Chemistry 24 (1976) 1221-1223
    • (1976) Journal of Agricultral Food Chemistry , vol.24 , pp. 1221-1223
    • Blair, D.1    Roderick, H.R.2
  • 13
    • 0024730172 scopus 로고
    • Oxidative desulfuration of chlorpyrifos, chlorpyrifos-methyl, and leptophos by rat brain and liver
    • Chambers J.E., and Chambers H.W. Oxidative desulfuration of chlorpyrifos, chlorpyrifos-methyl, and leptophos by rat brain and liver. Journal of Biochemical Toxicology 4 (1989) 201-203
    • (1989) Journal of Biochemical Toxicology , vol.4 , pp. 201-203
    • Chambers, J.E.1    Chambers, H.W.2
  • 19
    • 0034467512 scopus 로고    scopus 로고
    • Determination of dialkyl phosphates in human urine using gas chromatography-mass spectrometry
    • Hardt J., and Angerer J. Determination of dialkyl phosphates in human urine using gas chromatography-mass spectrometry. Journal of Analytical Toxicology 24 (2000) 678-684
    • (2000) Journal of Analytical Toxicology , vol.24 , pp. 678-684
    • Hardt, J.1    Angerer, J.2
  • 20
    • 0035009325 scopus 로고    scopus 로고
    • Metabolites of organophosphorous insecticides in urine specimens from inhabitants of a residential area
    • Heudorf U., and Angerer J. Metabolites of organophosphorous insecticides in urine specimens from inhabitants of a residential area. Environmental Research 86 (2001) 80-87
    • (2001) Environmental Research , vol.86 , pp. 80-87
    • Heudorf, U.1    Angerer, J.2
  • 21
    • 33646267951 scopus 로고    scopus 로고
    • Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation
    • Kim K.H., Isin E.M., Yun C.H., Kim D.H., and Guengerich F.P. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation. FEBS Journal 273 (2006) 2223-2231
    • (2006) FEBS Journal , vol.273 , pp. 2223-2231
    • Kim, K.H.1    Isin, E.M.2    Yun, C.H.3    Kim, D.H.4    Guengerich, F.P.5
  • 22
    • 0036057294 scopus 로고    scopus 로고
    • Temporal association of children's pesticide exposure and agricultural spraying: report of a longitudinal biological monitoring study
    • Koch D., Lu C.S., Fisker-Andersen J., Jolley L., and Fenske R.A. Temporal association of children's pesticide exposure and agricultural spraying: report of a longitudinal biological monitoring study. Environmental Health Perspectives 110 (2002) 829-833
    • (2002) Environmental Health Perspectives , vol.110 , pp. 829-833
    • Koch, D.1    Lu, C.S.2    Fisker-Andersen, J.3    Jolley, L.4    Fenske, R.A.5
  • 23
    • 21244497304 scopus 로고    scopus 로고
    • Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps
    • Krauser J.A., and Guengerich F.P. Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps. The Journal of Biological Chemistry 280 (2005) 19496-19506
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 19496-19506
    • Krauser, J.A.1    Guengerich, F.P.2
  • 25
    • 55449086592 scopus 로고    scopus 로고
    • Nanoparticle-based electrochemical immunosensor for the detection of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphate pesticides and nerve agents
    • Liu G., Wang J., Barry R., Petersen C., Timchalk C., Gassman P.L., and Lin Y. Nanoparticle-based electrochemical immunosensor for the detection of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphate pesticides and nerve agents. Chemistry 14 (2008) 9951-9959
    • (2008) Chemistry , vol.14 , pp. 9951-9959
    • Liu, G.1    Wang, J.2    Barry, R.3    Petersen, C.4    Timchalk, C.5    Gassman, P.L.6    Lin, Y.7
  • 26
    • 0031424649 scopus 로고    scopus 로고
    • Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington State
    • Loewenherz C., Fenske R.A., Simcox N.J., Bellamy G., and Kalman D. Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington State. Environmental Health Perspectives 105 (1997) 1344-1353
    • (1997) Environmental Health Perspectives , vol.105 , pp. 1344-1353
    • Loewenherz, C.1    Fenske, R.A.2    Simcox, N.J.3    Bellamy, G.4    Kalman, D.5
  • 27
    • 0035049921 scopus 로고    scopus 로고
    • Biological monitoring survey of organophosphorus pesticide exposure among pre-school children in the Seattle metropolitan area
    • Lu C., Knutson D.E., Fisker-Andersen J., and Fenske R.A. Biological monitoring survey of organophosphorus pesticide exposure among pre-school children in the Seattle metropolitan area. Environmental Health Perspectives 109 (2001) 299-303
    • (2001) Environmental Health Perspectives , vol.109 , pp. 299-303
    • Lu, C.1    Knutson, D.E.2    Fisker-Andersen, J.3    Fenske, R.A.4
  • 29
    • 0028001171 scopus 로고
    • Kinetic parameters of desulfuration and dearylation of parathion and chlorpyrifos by rat liver microsomes
    • Ma T., and Chambers J.E. Kinetic parameters of desulfuration and dearylation of parathion and chlorpyrifos by rat liver microsomes. Food and Chemical Toxicology 32 (1994) 763-767
    • (1994) Food and Chemical Toxicology , vol.32 , pp. 763-767
    • Ma, T.1    Chambers, J.E.2
  • 30
    • 0020522963 scopus 로고
    • Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group
    • Mizutani T., Yamamoto K., and Tajima K. Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group. Toxicology and Applied Pharmacology 69 (1983) 283-290
    • (1983) Toxicology and Applied Pharmacology , vol.69 , pp. 283-290
    • Mizutani, T.1    Yamamoto, K.2    Tajima, K.3
  • 32
    • 18044379803 scopus 로고    scopus 로고
    • Assessing exposure to organophosphorus pesticides by biomonitoring in epidemiologic studies of birth outcomes
    • Needham L.L. Assessing exposure to organophosphorus pesticides by biomonitoring in epidemiologic studies of birth outcomes. Environmental Health Perspectives 113 (2005) 494-498
    • (2005) Environmental Health Perspectives , vol.113 , pp. 494-498
    • Needham, L.L.1
  • 37
    • 0037387854 scopus 로고    scopus 로고
    • In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon
    • Poet T.S., Wu H., Kousba A.A., and Timchalk C. In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon. Toxicological Sciences 72 (2003) 193-200
    • (2003) Toxicological Sciences , vol.72 , pp. 193-200
    • Poet, T.S.1    Wu, H.2    Kousba, A.A.3    Timchalk, C.4
  • 38
    • 5044234937 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon
    • Poet T.S., Kousba A.A., Dennison S.L., and Timchalk C. Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon. Neurotoxicology 25 (2004) 1013-1030
    • (2004) Neurotoxicology , vol.25 , pp. 1013-1030
    • Poet, T.S.1    Kousba, A.A.2    Dennison, S.L.3    Timchalk, C.4
  • 39
    • 0034990759 scopus 로고    scopus 로고
    • Use of a pharmacokinetic model to assess chlorpyrifos exposure and dose in children, based on urinary biomarker measurements
    • Rigas M.L., Okino M.S., and Quackenboss J.J. Use of a pharmacokinetic model to assess chlorpyrifos exposure and dose in children, based on urinary biomarker measurements. Toxicological Sciences 61 (2001) 374-381
    • (2001) Toxicological Sciences , vol.61 , pp. 374-381
    • Rigas, M.L.1    Okino, M.S.2    Quackenboss, J.J.3
  • 40
    • 66049098146 scopus 로고    scopus 로고
    • Comparative chlorpyrifos pharmacokinetics via multiple routes of exposure and vehicles of administration in the adult rat
    • Smith J.N., Campbell J.A., Busby-Hjerpe A.L., Lee S., Poet T.S., Barr D.B., and Timchalk C. Comparative chlorpyrifos pharmacokinetics via multiple routes of exposure and vehicles of administration in the adult rat. Toxicology 261 (2009) 47-58
    • (2009) Toxicology , vol.261 , pp. 47-58
    • Smith, J.N.1    Campbell, J.A.2    Busby-Hjerpe, A.L.3    Lee, S.4    Poet, T.S.5    Barr, D.B.6    Timchalk, C.7
  • 42
    • 0020558910 scopus 로고
    • Deuterium isotope effect on metabolism of N-nitrosodimethylamine in vivo in rat
    • Swann P.F., Mace R., Angeles R.M., and Keefer L.K. Deuterium isotope effect on metabolism of N-nitrosodimethylamine in vivo in rat. Carcinogenesis 4 (1983) 821-825
    • (1983) Carcinogenesis , vol.4 , pp. 821-825
    • Swann, P.F.1    Mace, R.2    Angeles, R.M.3    Keefer, L.K.4
  • 44
    • 44649149558 scopus 로고    scopus 로고
    • Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat
    • Timchalk C., and Poet T.S. Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat. Neurotoxicology 29 (2008) 428-443
    • (2008) Neurotoxicology , vol.29 , pp. 428-443
    • Timchalk, C.1    Poet, T.S.2
  • 45
    • 0036191658 scopus 로고    scopus 로고
    • A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans
    • Timchalk C., Nolan R.J., Mendrala A.L., Dittenber D.A., Brzak K.A., and Mattsson J.L. A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans. Toxicological Sciences 66 (2002) 34-53
    • (2002) Toxicological Sciences , vol.66 , pp. 34-53
    • Timchalk, C.1    Nolan, R.J.2    Mendrala, A.L.3    Dittenber, D.A.4    Brzak, K.A.5    Mattsson, J.L.6
  • 46
    • 32044468978 scopus 로고    scopus 로고
    • Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos
    • Timchalk C., Poet T.S., and Kousba A.A. Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos. Toxicology 220 (2006) 13-25
    • (2006) Toxicology , vol.220 , pp. 13-25
    • Timchalk, C.1    Poet, T.S.2    Kousba, A.A.3
  • 47
    • 34447098553 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethylthiophosphate and 3,5,6-trichloro-2-pyridinol in the rat
    • Timchalk C., Busby A., Campbell J.A., Needham L.L., and Barr D.B. Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethylthiophosphate and 3,5,6-trichloro-2-pyridinol in the rat. Toxicology 237 (2007) 145-157
    • (2007) Toxicology , vol.237 , pp. 145-157
    • Timchalk, C.1    Busby, A.2    Campbell, J.A.3    Needham, L.L.4    Barr, D.B.5
  • 48
    • 34547839628 scopus 로고    scopus 로고
    • An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat
    • Timchalk C., Kousba A.A., and Poet T.S. An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat. Toxicological Sciences 98 (2007) 348-365
    • (2007) Toxicological Sciences , vol.98 , pp. 348-365
    • Timchalk, C.1    Kousba, A.A.2    Poet, T.S.3
  • 49
    • 0016174577 scopus 로고
    • Preparation and properties of partially purified cytochrom P450 and rduced nicotinamide adenine dinucleotide phosypahate-cytochrome P450 reductase from rabbit liver microsomes
    • van der Hoeven T.A., and Coon M.J. Preparation and properties of partially purified cytochrom P450 and rduced nicotinamide adenine dinucleotide phosypahate-cytochrome P450 reductase from rabbit liver microsomes. Journal of Biological Chemistry 249 (1974) 6302-6310
    • (1974) Journal of Biological Chemistry , vol.249 , pp. 6302-6310
    • van der Hoeven, T.A.1    Coon, M.J.2
  • 50
    • 0015114399 scopus 로고
    • Deuterium isotope effects in the metabolism of N-alkylsubstituted amphetamines in man
    • Vree T.B., Gorgels J.P., Muskens A.T., and van Rossum J.M. Deuterium isotope effects in the metabolism of N-alkylsubstituted amphetamines in man. Clinica Chimica Acta 34 (1971) 333-344
    • (1971) Clinica Chimica Acta , vol.34 , pp. 333-344
    • Vree, T.B.1    Gorgels, J.P.2    Muskens, A.T.3    van Rossum, J.M.4
  • 51
    • 0015090319 scopus 로고
    • Deuterium isotope effects and stereochemistry in the dealkylation and deamination of amphetamines and ephedrines in man
    • Vree T.B., Muskens A.T., and van Rossum J.M. Deuterium isotope effects and stereochemistry in the dealkylation and deamination of amphetamines and ephedrines in man. Xenobiotica 1 (1971) 385-386
    • (1971) Xenobiotica , vol.1 , pp. 385-386
    • Vree, T.B.1    Muskens, A.T.2    van Rossum, J.M.3
  • 52
    • 56449100815 scopus 로고    scopus 로고
    • Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma
    • Wang H., Wang J., Timchalk C., and Lin Y. Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma. Analytical Chemistry 80 (2008) 8477-8484
    • (2008) Analytical Chemistry , vol.80 , pp. 8477-8484
    • Wang, H.1    Wang, J.2    Timchalk, C.3    Lin, Y.4


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