Oral and dermal absorption of chlorpyrifos: A human volunteer study

Occupational and Environmental Medicine

Volumn 56, Issue 1, 1999, Pages 10-13

  Griffin, P ^a   Mason, H ^a   Heywood, K ^a   Cocker, J ^a  

^a HEALTH AND SAFETY LABORATORY   (United Kingdom)

Author keywords

Biological monitoring; Chlorpyrifos; Organophosphorus; Pesticide

Indexed keywords

ACETYLCHOLINESTERASE; CHLORPYRIFOS; ERYTHROCYTE ENZYME; ORGANOPHOSPHATE PESTICIDE;

ADULT; ARTICLE; BIOLOGICAL MONITORING; BLOOD SAMPLING; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; METABOLITE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PRIORITY JOURNAL; SKIN ABSORPTION; SKIN SURFACE; TIME; URINALYSIS;

EID: 0032939378     PISSN: 13510711     EISSN: None     Source Type: Journal    
DOI: 10.1136/oem.56.1.10     Document Type: Article

References (9)

1. Sultanos LG, Shao M, Murphy SD. The role of hepatic biotransformation in mediating the acute toxicity of the phosphorothioate insecticide chlorpyrifos. Toxicol Appl Pharmacol 1984;73:60-8.
2. Richardson RJ. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorous compounds: a critical review of the literature. J Toxicol Environ Health 1995;44:135-65.
3. Fenske R, Elkner K. Multi route exposure assessment with biological monitoring of urban pesticide applicators during structural control treatments with chlorpyrifos. Toxicol Ind Health 1990;6:349-71.
4. Health and Safety Executive. Occupational exposure limits. London: The Stationary Office, 1998. (Publication: EH 40/98.)
5. Health and Safety Executive. Biological monitoring of workers exposed to organo-phosphorous pesticides. London: Her Majesty's Stationary Office, 1987. (Publication: MS 17.)
6. Nolan RJ, Rick DL, Freshour NL, et al. Chlorpyrifos: pharmacokinetics in human volunteers. Toxicol Appl Pharmacol 1984;73:8-15.
7. Nutley BP, Cocker J. Biological monitoring of workers occupationally exposed to organophosphate pesticides. Pesticide Science 1993;38:315-22.
8. Aprea C, Sciarra G, Sartorelli P, et al. Biological monitoring of exposure to organophosphorous insecticides by assay of urinary alkylphosphates: influence of protective measures during manual operations with treated plants. Int Arch Occup Environ Health 1994;66:333-8.
9. Mason HJ, Lewis PJ. A study of the intra-individual variation in plasma and red cell cholinesterase activity and its application to the detection of organophosphate pesticides. J Soc Occup Med 1989;39:121-4.