Di-alkyl phosphate biomonitoring data: Assessing cumulative exposure to organophosphate pesticides

Regulatory Toxicology and Pharmacology

Volumn 37, Issue 3, 2003, Pages 382-395

  Duggan, Angelina ^a   Charnley, Gail ^b   Chen, William ^c   Chukwudebe, Amechi ^d   Hawk, Robert ^e   Krieger, Robert I ^f   Ross, John ^g   Yarborough, Charles ^h  

^a CropLife Foundation   (United States)

^b HealthRisk Strategies   (United States)

^c DOW AGROSCIENCES LLC   (United States)

^d SYNGENTA CROP PROTECTION   (United States)

^e Gowan Company   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g Infoscientificcom Inc   (United States)

^h BASF CORPORATION   (United States)

Author keywords

Aggregate; Alkyl phosphate; Biomonitoring; Cumulative; Exposure assessment; Organophosphate; Risk

Indexed keywords

ORGANOPHOSPHATE PESTICIDE;

ANALYSIS; ARTICLE; BIOLOGICAL MONITORING; DRUG ABSORPTION; DRUG ACCUMULATION; EVALUATION; FUNCTIONAL ASSESSMENT; HUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; PUBLIC HEALTH SERVICE; RELIABILITY; RISK ASSESSMENT; RISK MANAGEMENT; SCREENING TEST; URINE LEVEL;

EID: 0038240874     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0273-2300(03)00031-X     Document Type: Article

References (73)

1. Adgate J.L., Barr D.B., Clayton C.A., Eberly L.E., Freeman N.C.G., Lioy P.J., Needham L.L., Pellizzari E.D., Quankenboss J.J., Roy A., Sexton K. Measurement of children's exposure to pesticides: analysis of urinary metabolites levels in a probability-based sample. Environ. Health Persp. 109:2001;583-590.
2. Aprea C., Sciarra G., Orsi D., Boccalon P., Sartorelli P., Sartorelli E. Urinary excretion of alkylphosphates in the general population (Italy). Sci. Total Environ. 177:1996;37-41.
3. Aprea C., Sciarra G., Lunghini L., Centi L., Ceccarelli F. Evaluation of respiratory and cutaneous doses and urinary excretion of alkylphosphates by workers in greenhouses treated with omethoate, fenitrothhion, and tolclofos-methyl. Am. Industr. Hygiene Assoc. J. 62:2001;87-95.
4. Aprea C., Strombi M., Novelli M.T., Lunghini L., Bozzi N. Biologic monitoring of exposure to orgnaphosphate pesticides in 195 Italian children. Environ. Health Persp. 108:2000;521-525.
5. Azaroff L.S. Biomarkers of exposure to organophosphorous insecticide among farmers' families in rural El Salvador: factors associated with exposure. Environ. Res. 80:1999;138-147.
6. Baugher, D., 1989. Exposure of harvesters to Zolone EC brand insecticide applied to grapes in California. Registration Document #157-058, Record #122312. Cal/EPA Department of Pesticide Regulation, Registration Branch, Sacramento, CA.
7. Berteau P., Knaak J., Mengle D., Schreider J. Insecticide absorption from indoor surfaces. Wang R., Franklin Honeycutt R., Reinert J. American Chemical Society Symposium Series. vol. 382:1989;315-326 American Chemical Society, Washington, DC.
8. 14C-Chlorfenvinphos in soils and in crops grown in the soils. J. Sci. Food Agric. 19:1967;143-150.
9. Boeniger M.F., Lowry L.K., Rosenberg J. Interpretation of urine results used to assess chemical exposure with emphasis on creatinine adjustments: a review. Am. Ind. Hyg. Assoc. J. 54:1993;615-627.
10. Bradway D.E., Shafik T.M. Malathion exposure studies. Determination of mono- and dicarboxylic acids and alkyl phosphates in urine. J. Agric. Food Chem. 25:1977;1342-1344.
11. Brady U.E., Arthur B.W. Metabolism of O,O-dimethyl-O-[(methylthio)-m-tolyl]phosphorothioate by white rats. J. Econ. Entomol. 54:1961;1232-1236.
12. Bravo R., Driskell W.J., Whitehead R.J., Needham L.L., Barr D.B. Quantification of dialkyl phosphate metabolites of organophosphate pesticides in human urine using GC-MS-MS with isotopic internal standards. J. Anal. Tox. 26:2002;245-252.
13. Brewster D.W., Warren J., Hopkins W.E. Metabolism of glyphosate in Sprague-Dawley rats: tissue distribution, identification, and quatitation of glyphosate-derived materials following a single oral dose. Fundam. Appl. Toxicol. 17:1991;43-51.
14. Buchanan D., Pilkington A., Sewell C., Tannahill S.N., Kidd M.W., Cherrie B., Hurley J.F. Estimation of cumulative exposure to organophosphate sheep dips in a study of chronic neurological health effects among United Kingdom sheep dippers. Occup. Environ. Med. 58:2001;694-701.
15. 2 -1,3,4-thiadiazolin-5-one (Geigy GS-13005) in plants and animals J. Agric. Food Chem. 16:1968;610-616.
16. Bull D.L., Lindquist D.A. Metabolism of 3-hydroxy-N,N-dimethyl-crotonamide dimethyl phosphate by cotton plants, insects and rats. J. Agric. Food Chem. 12:1964;310-317.
17. Bull D.L., Ridgeway R.L. Metabolism of trichlorfon in animals and plants. J. Agric. Food Chem. 17:1969;837-841.
18. CDC, 2001. National Report on Human Exposure to Environmental Chemicals. Available from http://www.cdc.gov/nceh/dls/report/.
19. CDC, 2003. Second National Report on Human Exposure to Environmental Chemicals. Available from http://www.cdc.gov/exposurereport.
20. Chukwudebe A.C., Hussain M.A., Oloffs P.C. Hydrolytic and metabolic products of acephate in water and mouse liver. J. Environ. Sci. Health B. 19(6):1984;501-522.
21. Coye M.J., Lowe J.A., Maddy K.T. Biological monitoring of agricultural workers exposed to pesticides: II. Monitoring of intact pesticides and their metabolites. J. Occup. Med. 28:1986;628-636.
22. Dary C.C., Blancato J.N., Castles M., Reddy V., Cannon M., Saleh M.A., Cash G.G. Dermal absorption and disposition of formulations of malathion in Sprague-Dawley rats and humans. Saleh M.A., Blancato J.N., Nauman C.H. Biomarkers of Human Exposure to Pesticides. American Chemical Society Symposium Series No. 542. 1994;American Chemical Society, Washington, DC, USA.
23. Davies J.E., Peterson J.C. Surveillance of occupational, accidental, and incidental exposure to organophosphate pesticides using urine alkyl phosphate and phenolic metabolite measurements. Ann. N.Y. Acad. Sci. 837:1997;257-268.
24. De Pietri-Tonelli P., Bazzi B., Santi R. Rogor (dimethoate) residues in food crops. Res. Rev. 11:1968;60-99.
25. Devine J.M., Kinoshita G.B., Peterson R.P., Picard G.L. Farm worker exposure to terbufos (Phosphorodithioic acid,S-(tert-butylthio) methyl O,O-diethyl ester) during planting operations of corn. Arch. Environ. Contam. Toxicol. 15:1986;113-119.
26. Dong M.H., Ross J.H., Thongsinthusak T., Krieger R. Use of spot urine sample results in physiologically based pharmacokinetic modeling of absorbed malathion doses in humans. Blancato J.N., Brown R.N., Dary C.C., Saleh M.A. Biomarkers for Agrochemicals and Toxic Substances, Applications and Risk Assessment. ACS Symposium Series Series 643. 1996;American Chemical Society, Washington, DC, USA.
27. EPA Office of Pesticide Programs 2000. Available from http://epa.gov/pesticides/op/ddvp/hedrisk.pdf.
28. EPA Office of Pesticide Programs, 2002. Available from http://epa.gov/scipoly/sap/index.htm.
29. EPA Office of Pesticide Programs, 2001. Available from http://epa.gov/pesticides/cumulative/rra-op.htm.
30. EPA, 1992. Guidelines for Exposure Assessment. Risk Assessment Forum, Office of Research and Development, US EPA, Washington, DC, EPA/600/Z-92/001.
31. Eto M. Organophosphorus Pesticides: Organic and Biological Chemistry. 1979;CRC Press, Boca Raton, FL.
32. Fenske R.A. Correlation of fluorescent tracer measurements of dermal exposure and urinary metabolite excretion during occupational exposure to malathion. Am. Ind. Hyg. Assoc. J. 49:1988;438-444.
33. Fenske R.A., Lu C., Simcox N.J., Lowewnherz C., Touchstone J., Moate T.F., Allen E.H., Kissel J.C. Strategies for assessing children's organophosphorus pesticide exposures in agricultural communities. J. Expos. Anal. Environ. Epidemiol. 10:2001;662-671.
34. Franklin C.A., Muir N.I., Moody R.P. The use of biological monitoring in rthe estimation of exposure during the application of pesticides. Toxicol. Lett. 33:1986;127-136.
35. Fukuda H., Masuda T., Miyahara Y., Tomizawa T. Fate of O,O-dimethyl O-(3-methylmercaptophenyl) thiophosphate sprayed on rice plant. Jpn. J. Appl. Entomol. Zool. 6:1962;230-236.
36. Gompertz D. Solvents - the relationship between biological monitoring strategies and metabolic handling: a review. Ann. Occup. Hyg. 23:1980;405-410.
37. Griffin P., Mason H., Heywood K., Cocker J. Oral and dermal absorption of chlorpyrifos: a human volunteer study. Occup. Environ. Med. 56:1999;10-13.
38. Griffith J.G., Duncan R.C. Alkyl phosphate residue values in the urine of Florida citrus fieldworkers compared to the national health and nutrition examination survey (HANES) sample. Bull. Environ. Contam. Toxicol. 34:1985;210-215.
39. Hayes L.L., Wise R.A., Weir F.W. Assessment of occupational exposure to organophosphates in pest control operators. Am. Ind. Hyg. Assoc. J. 41:1980;568-575.
40. Heudorf U., Angerer J. Metabolites of organophosphorus insecticides in urine specimens from inhabitants of a residential area. Environ. Res. 86:2001;80-87.
41. Hollingworth R.M. Comparative metabolism and selectivity of organophosphate and carbamate insecticides. Bull. World Health Org. 44:1971;155-170.
42. Kansouh A.S.H., Hopkins T.L. Diazinon absorption, translocation, and metabolism in bean plants. J. Agric. Food Chem. 16:1968;446-450.
43. Karns J.S., Muldoon M.T., Mulbrey W.W., Derbyshire M.R., Kearney P.C. Use of microorganisms and microbial systems in the degradation of pesticides. Am. Chem. Soc. Symp. Ser. 334:1987;156-170.
44. Kolpin D.W., Furlong E., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 36:2002;1202-1211.
45. Krieger, R., 1993. Determination of mevinphos exposures of handlers. Registration Document #263-033, Record #68690. Cal/EPA Department of Pesticide Regulation, Registration Branch, Sacramento, CA.
46. Krieger R.I., Dinoff T.M. Malathion deposition, metabolite clearance, and cholinesterase status of date dusters and harvesters in California. Arch. Environ. Contam. Toxicol. 38:2000;546-553.
47. Krieger R.I., Bernard C.E., Dinoff T.M., Ross J.H., Williams R.L. Biomonitoring of persons exposed to insecticides used in residences. Ann. Occup. Hyg. Suppl. 2001;143-153.
48. Lowenherz C., Fenske R.A., Simcox N.J., Bellamy G., Kalman D. Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington state. Environ. Health Persp. 105:1997;1344-1353.
49. Lu C., Knutson D.E., Fisker-Andersen J., Fenske R.A. Biological monitoring survey of organophosophorus pesticide exposure among pre-school children in the Seattle metropolitan area. Environ. Health Persp. 109:2001;299-303.
50. Macintosh D.L., Needham L.L., Hammerstrom K.A., Ryan P.B. A longitudinal investigation of selected pesticide metabolites in urine. J. Exp. Anal. Environ. Epidemiol. 9:1999;494-501.
51. McCurdy, S.A., Schneider, F.A., Steenland, K., Wilson, B., Krieger, R., Hernandez, B., Spencer, J., Margetich, S., 1994. Assessment of azinphosmethyl exposure in California peach.
52. Menzer R.E., Casida J.E. Nature of toxic metabolites formed in mammals, insects, and plants from 3-(dimethoxyphosphinyloxy)-N,N-dimethyl-cis-crotonamide and its N-methyl analog. J. Agric. Food Chem. 13:1965;102-112.
53. Murphy R.S., Kutz, Strassman S.C. Selected pesticide residues or metabolites in blood and urine specimens from a general population survey. Environ. Health Persp. 48:1983;81-86.
54. Nigg H.N., Stamper J.H. Biological monitoring for pesticide dose determination. Wang R.G.M., Franklin C.A., Honeycutt, Reinert J.C. Biological Monitoring for Pesticide Exposure-measurement, Estimation, and Risk Reduction. ACS Symposium Series 382. 1989;6-27 ACS, Washington, DC.
55. Nolan R.J., Rick K.L., Freshour N.L., Saunders J.H. Chlorpyrifos: pharmacokinetics in human volunteers. Toxicol. Appl. Pharmacol. 73:1984;8-15.
56. O'Brien R.D. Insecticides Action and Metabolism. 1967;67-77 Academic Press, New York.
57. O'Rourke M.K., Lizardi P.S., Rogan S.P., Freeman N.C., Aguirre A., Saint C.G. Pesticide exposure and creatinine variation among children. J. Expos. Anal. Environ. Epidemiol. 10:2001;672-681.
58. PSD, 1991. Pesticide Safety Directorate (UK MAFF), Evaluation No. 35. Diazinon. Evaluation Document, April 1991.
59. Racke K.D. Environmental fate of chlorpyrifos. Rev. Environ. Contam. Toxicol. 131:1993;1-154.
60. Richards D.M., Kraus J.F., Kurtz P., Borhani N.O., Mull R., Winterlin W., Kilgore W.W. A controlled field trial of physiological responses to organophosphate residues in farm workers. J. Environ. Pathol. Toxicol. 2:1978;493-512.
61. Ross J.H., Driver J.H., Cochran R.C., Thongsinthusak T., Krieger R.I. Could pesticide toxicology studies be more relevant to occupational risk assessment? Ann. Occup. Hygiene. 45(Suppl. 1):2001;5-17.
62. Simcox N.J., Camp J., Kalman D., Stebbins A., Bellamy G., Lee I.C., Fenske R. Farmworker exposure to organophosphorus pesticide residues during apple thinning in central Washington state. Am. Ind. Hyg. Assoc. J. 60:1999;752-761.
63. Snyder, W.S., Cook, M.J. Nasset, E.S., Karhausen, L.R., Howells, G.P., Tipton, I.H., 1975. Report of the task group on reference man: a report prepared by a task group of committee 2 of the International Commission on Radiological Protection. ICRP Report No. 23, Pergamon Press, Oxford.
64. 14C labeled methamidophos from Tamaron 600 SL formulation administered to healthy volunteers. HSM-01008, Cal/EPA Department of Pesticide Regulation, Sacramento, CA.
65. Thongsinthusak T., Ross J.H., Saiz S., Krieger R. Estimation of dermal absorption using the exponential saturation model. Reg. Toxicol. Pharmacol. 29:1999;37-43.
66. Urone P.F., Anders H.K. Determination of small amounts of chromium in human blood, tissues, and urine. Anal. Chem. 22:1950;1317-1321.
67. Vasilic Z., Drevenkar V., Frobe Z., Strengl B., Tkalcevic B. The metabolites of organophosphorus pesticides in urine as an indicator of occupational exposure. Toxicol. Environ. Chem. 14:1987;111-127.
68. Weisskopf C.P., Seiber J.N., Maizlish N., Schenker M. Personnel exposure to diazinon in a supervised pest eradication program. Arch. Environ. Contam. Toxicol. 17:1988;201-212.
69. Wester R.C., Maibach H.I. In vivo percutaneous absorption and decontamination of pesticides in humans. J. Toxicol. Environ. Health. 16:1985;25-37.
70. Wester R.C., Maibach H.I., Melendres J., Sedik L., Knaak J., Wang R. In vivo and in vitro percutaneous absorption and skin evaporation of isofenphos in man. Fundam. Appl. Toxicol. 19:1992;521.
71. Wester R.C., Sedik L., Melendres J., Logan F., Maibach H.I., Russell I. Percutaneous absorption of diazinon in humans. Food Chem. Toxicol. 31:1993;569-572.
72. Whitmore, R.W., Kelly, J.E., Reading, P.L., 1992. National Home and Garden Pesticide Use Survey: Final Report. Sponsored by the U.S. Environmental Protection Agency, Office of Pesticide Programs and Toxic Substances, Washington, DC, NTIS PB92-174739.
73. Whyatt R.M., Barr D.B. Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure: a validation study. Environ. Health Persp. 109:2001;417-420.