메뉴 건너뛰기




Volumn 164, Issue 10, 2000, Pages 5446-5452

Complement C1q is dramatically up-regulated in brain microglia in response to transient global cerebral ischemia

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q;

EID: 0343962980     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.10.5446     Document Type: Article
Times cited : (146)

References (46)
  • 2
    • 0030779518 scopus 로고    scopus 로고
    • Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain
    • Shen, Y., R. Li, E. McGeer, and P. McGeer. 1997. Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain. Brain Res. 769:391
    • (1997) Brain Res. , vol.769 , pp. 391
    • Shen, Y.1    Li, R.2    McGeer, E.3    McGeer, P.4
  • 3
    • 0030271257 scopus 로고    scopus 로고
    • Expression of complement in the brain: Role in health and disease
    • Morgan, B. P., and P. Gasque. 1996. Expression of complement in the brain: role in health and disease. Immunol. Today 17:461.
    • (1996) Immunol. Today , vol.17 , pp. 461
    • Morgan, B.P.1    Gasque, P.2
  • 4
    • 0030679662 scopus 로고    scopus 로고
    • Complement and complement deficiencies
    • Whaley K., and W. Schwaeble. 1997. Complement and complement deficiencies. Semin. Liver Dis. 17:297.
    • (1997) Semin. Liver Dis. , vol.17 , pp. 297
    • Whaley, K.1    Schwaeble, W.2
  • 5
    • 0030828544 scopus 로고    scopus 로고
    • Neurons express proteins of the classical complement pathway in Alzheimer disease
    • Terai, K., D. G. Walker, E. G. McGeer, and P. L. McGeer. 1997. Neurons express proteins of the classical complement pathway in Alzheimer disease. Brain Res. 769:385.
    • (1997) Brain Res. , vol.769 , pp. 385
    • Terai, K.1    Walker, D.G.2    McGeer, E.G.3    McGeer, P.L.4
  • 6
    • 0031031747 scopus 로고    scopus 로고
    • Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: Implications for Alzheimer's disease pathogenesis
    • Velazquez, P., D. Cribbs, T. Poulos, and A. Tenner 1997. Aspartate residue 7 in amyloid β-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis. Nat. Med. 3:77.
    • (1997) Nat. Med. , vol.3 , pp. 77
    • Velazquez, P.1    Cribbs, D.2    Poulos, T.3    Tenner, A.4
  • 7
    • 0029932195 scopus 로고    scopus 로고
    • Localization and cell association of C1q in Alzheimer's disease brain
    • Afagh, A., B. Cummings, D. Cribbs, C. Cotman, and A. Tenner. 1996. Localization and cell association of C1q in Alzheimer's disease brain. Exp. Neurol. 138:22.
    • (1996) Exp. Neurol. , vol.138 , pp. 22
    • Afagh, A.1    Cummings, B.2    Cribbs, D.3    Cotman, C.4    Tenner, A.5
  • 8
  • 9
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer, P. L., and E. G. McGeer. 1995. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Brain Res. Rev. 21:195.
    • (1995) Brain Res. Brain Res. Rev. , vol.21 , pp. 195
    • McGeer, P.L.1    McGeer, E.G.2
  • 10
    • 0030020028 scopus 로고    scopus 로고
    • Neurofibrillary tangles of Guam Parkinson-dementia are associated with reactive microglia and complement proteins
    • Schwab, C., J. Steele, and P. McGeer. 1996. Neurofibrillary tangles of Guam Parkinson-dementia are associated with reactive microglia and complement proteins. Brain Res. 707:196.
    • (1996) Brain Res. , vol.707 , pp. 196
    • Schwab, C.1    Steele, J.2    McGeer, P.3
  • 11
    • 0028265749 scopus 로고
    • Increased concentration of C4d complement protein in the cerebrospinal fluids in progressive supranuclear palsy
    • Yamada, T., I. Moroo, Y. Koguchi, M. Asahina, and K. Hirayama. 1994. Increased concentration of C4d complement protein in the cerebrospinal fluids in progressive supranuclear palsy. Acta Neurol. Scand. J. 89:42.
    • (1994) Acta Neurol. Scand. J. , vol.89 , pp. 42
    • Yamada, T.1    Moroo, I.2    Koguchi, Y.3    Asahina, M.4    Hirayama, K.5
  • 13
    • 0032080456 scopus 로고    scopus 로고
    • Dual implication of 2′,3′-cyclic nucleotide 3′ phosphodiesterase as major autoantigen and C3 complement-binding protein in the pathogenesis of multiple sclerosis
    • Walsh, M. J., and J. M. Murray. 1998. Dual implication of 2′,3′-cyclic nucleotide 3′ phosphodiesterase as major autoantigen and C3 complement-binding protein in the pathogenesis of multiple sclerosis. J. Clin. Invest. 101:1923.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1923
    • Walsh, M.J.1    Murray, J.M.2
  • 14
    • 0032055221 scopus 로고    scopus 로고
    • The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: Analysis in multiple sclerosis and bacterial meningitis
    • Gasque, P., S. K. Singhrao, J. W. Neal, P. Wang, S. Sayah, M. Fontaine, and B. P. Morgan. 1998. The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis. J. Immunol. 160: 3543.
    • (1998) J. Immunol. , vol.160 , pp. 3543
    • Gasque, P.1    Singhrao, S.K.2    Neal, J.W.3    Wang, P.4    Sayah, S.5    Fontaine, M.6    Morgan, B.P.7
  • 16
    • 0031570894 scopus 로고    scopus 로고
    • TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis
    • Stahel, P. F., K. Frei, H. P. Eugster, A. Fontana, K. M. Hummel, R. A. Wetsel, R. S. Ames, and S. R. Barnum. 1997. TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis. J. Immunol. 159:861.
    • (1997) J. Immunol. , vol.159 , pp. 861
    • Stahel, P.F.1    Frei, K.2    Eugster, H.P.3    Fontana, A.4    Hummel, K.M.5    Wetsel, R.A.6    Ames, R.S.7    Barnum, S.R.8
  • 18
    • 0032571330 scopus 로고    scopus 로고
    • Gene expression in scrapie: Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts
    • Dandoy-Dron, F., F. Guillo, L. Benboudjema, J. P. Deslys, C. Lasmezas, D. Dormont, M. G. Tovey, and M. Dron. 1998. Gene expression in scrapie: cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J. Biol. Chem. 273:7691.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7691
    • Dandoy-Dron, F.1    Guillo, F.2    Benboudjema, L.3    Deslys, J.P.4    Lasmezas, C.5    Dormont, D.6    Tovey, M.G.7    Dron, M.8
  • 20
    • 0028898594 scopus 로고
    • Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP)-2 in the hypoglossal nucleus following peripheral nerve injury
    • Svensson, M., L. Liu, P. Mattsson, B. Morgan, and H. Aldskogius. 1995. Evidence for activation of the terminal pathway of complement and upregulation of sulfated glycoprotein (SGP)-2 in the hypoglossal nucleus following peripheral nerve injury. Mol. Chem. Neuropathol. 24:53.
    • (1995) Mol. Chem. Neuropathol. , vol.24 , pp. 53
    • Svensson, M.1    Liu, L.2    Mattsson, P.3    Morgan, B.4    Aldskogius, H.5
  • 21
    • 0030960788 scopus 로고    scopus 로고
    • Kainic acid and decorticating lesions stimulate the synthesis of C1q protein in adult rat brain
    • Goldsmith, S. K., P. Wals, I. Rozovsky, T. E. Morgan, and C. E. Finch. 1997. Kainic acid and decorticating lesions stimulate the synthesis of C1q protein in adult rat brain. J. Neurochem. 68:2046.
    • (1997) J. Neurochem. , vol.68 , pp. 2046
    • Goldsmith, S.K.1    Wals, P.2    Rozovsky, I.3    Morgan, T.E.4    Finch, C.E.5
  • 23
    • 0029876687 scopus 로고    scopus 로고
    • Perforant path transection induces complement C9 deposition in hippocampus
    • Johnson, S., C. Young-Chan. N. Laping, and C. Finch. 1996. Perforant path transection induces complement C9 deposition in hippocampus. Exp. Neurol. 138:198.
    • (1996) Exp. Neurol. , vol.138 , pp. 198
    • Johnson, S.1    Young-Chan, C.2    Laping, N.3    Finch, C.4
  • 24
    • 0031027062 scopus 로고    scopus 로고
    • Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: Correlation with blood-brain barrier damage and astroglial reactions
    • Jensen, M., B. Finsen, and J. Zimmer. 1997. Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: correlation with blood-brain barrier damage and astroglial reactions. Exp. Neurol. 143:103.
    • (1997) Exp. Neurol. , vol.143 , pp. 103
    • Jensen, M.1    Finsen, B.2    Zimmer, J.3
  • 25
    • 0027955054 scopus 로고
    • Early response of brain resident microglia to kainic acid-induced hippocampal lesions
    • Akiyama, H., I. Tooyama, H. Kondo, K. Ikeda, H. Kimura, E. McGeer, and P. McGeer. 1994. Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain Res. 635:257.
    • (1994) Brain Res. , vol.635 , pp. 257
    • Akiyama, H.1    Tooyama, I.2    Kondo, H.3    Ikeda, K.4    Kimura, H.5    McGeer, E.6    McGeer, P.7
  • 26
    • 0028134829 scopus 로고
    • Selective expression of clusterin (SGP-2) and complement C1qb and C4 during responses to neurotoxins in vivo and in vitro
    • Rozovsky, I., T. Morgan, D. Willoughby, M. Dugichi-Djordjevich, G. Pasinetti, S. Johnson, and C. Finch. 1994. Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro. Neuroscience 62:741.
    • (1994) Neuroscience , vol.62 , pp. 741
    • Rozovsky, I.1    Morgan, T.2    Willoughby, D.3    Dugichi-Djordjevich, M.4    Pasinetti, G.5    Johnson, S.6    Finch, C.7
  • 27
    • 0028920876 scopus 로고
    • The expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis
    • Dietzschold, B., W. Schwaeble, M. K.-H. Schäfer, F. Petry, Y. Zehng, H. Zheng, T. Fink, M. Loos, and E. Weihe. 1995. The expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis. J. Neurol. Sci. 130:11.
    • (1995) J. Neurol. Sci. , vol.130 , pp. 11
    • Dietzschold, B.1    Schwaeble, W.2    Schäfer, M.K.-H.3    Petry, F.4    Zehng, Y.5    Zheng, H.6    Fink, T.7    Loos, M.8    Weihe, E.9
  • 28
    • 0030568986 scopus 로고    scopus 로고
    • Complement gene expression in mouse microglia and astrocytes in culture: Comparisons with mouse peritoneal macrophages
    • Haga, S., T. Aizawa, T. Ishii, and K. Ikeda. 1996. Complement gene expression in mouse microglia and astrocytes in culture: comparisons with mouse peritoneal macrophages. Neurosci. Lett. 216:191.
    • (1996) Neurosci. Lett. , vol.216 , pp. 191
    • Haga, S.1    Aizawa, T.2    Ishii, T.3    Ikeda, K.4
  • 29
    • 0028805371 scopus 로고
    • Cultured rat microglia express C1q and receptor for C1q: Implications for amyloid effects on microglia
    • Korotzer, A., J. Watt, D. Cribbs, A. Tenner, D. Burdick, C. Glabe, and C. Cotman. 1995. Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia. Exp. Neurol. 134:214.
    • (1995) Exp. Neurol. , vol.134 , pp. 214
    • Korotzer, A.1    Watt, J.2    Cribbs, D.3    Tenner, A.4    Burdick, D.5    Glabe, C.6    Cotman, C.7
  • 30
    • 0029053689 scopus 로고
    • Complement expression in human brain: Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines
    • Gasque, P., M. Fontaine, and B. Morgan. 1995. Complement expression in human brain: biosynthesis of terminal pathway components and regulators in human glial cells and cell lines. J. Immunol. 154:4726.
    • (1995) J. Immunol. , vol.154 , pp. 4726
    • Gasque, P.1    Fontaine, M.2    Morgan, B.3
  • 31
    • 0029270425 scopus 로고
    • Microglia, the first line of defence in brain pathologies
    • Kreutzberg, G. W. 1995. Microglia, the first line of defence in brain pathologies. Arzneim.-Forsch.45:357.
    • (1995) Arzneim.-Forsch. , vol.45 , pp. 357
    • Kreutzberg, G.W.1
  • 32
    • 0342592138 scopus 로고    scopus 로고
    • Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
    • Nolte, C., T. Moller, T. Walter, and H. Kettenmann. 1996. Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton. Neuroscience 73: 1091.
    • (1996) Neuroscience , vol.73 , pp. 1091
    • Nolte, C.1    Moller, T.2    Walter, T.3    Kettenmann, H.4
  • 33
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli, W. A., and J. B. Brierley. 1979. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267.
    • (1979) Stroke , vol.10 , pp. 267
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 34
    • 0028790714 scopus 로고
    • Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen: Identification of specific cell types by in situ hybridization and immunohistochemical analysis
    • Schwaeble, W., M. K.-H. Schäfer, F. Petry, T. Fink, D. Knebel, E. Weihe, and M. Loos. 1995. Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen: identification of specific cell types by in situ hybridization and immunohistochemical analysis. J. Immunol. 155:4971.
    • (1995) J. Immunol. , vol.155 , pp. 4971
    • Schwaeble, W.1    Schäfer, M.K.-H.2    Petry, F.3    Fink, T.4    Knebel, D.5    Weihe, E.6    Loos, M.7
  • 35
    • 0021770917 scopus 로고
    • Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
    • Melten, D. A., P. A. Krieg, M. R. Rebagliati, T. Maniatis, K. Zinn, and M. R. Green. 1984. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:7035.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 7035
    • Melten, D.A.1    Krieg, P.A.2    Rebagliati, M.R.3    Maniatis, T.4    Zinn, K.5    Green, M.R.6
  • 36
    • 85053944545 scopus 로고
    • In situ hybridization immunohistochemistry
    • E. D. London, ed. CRC Press, Boca Raton
    • Schäfer, M. K.-H., J. P. Herman, and S. J. Watson. 1992. In situ hybridization immunohistochemistry. In Imaging Drug Action in the Brain. E. D. London, ed. CRC Press, Boca Raton, p. 337.
    • (1992) Imaging Drug Action in the Brain , pp. 337
    • Schäfer, M.K.-H.1    Herman, J.P.2    Watson, S.J.3
  • 37
    • 0028090040 scopus 로고
    • Spinal prodynorphin gene expression in collagen-induced arthritis, influence of the glucocorticosteroid budesonide
    • Persson, S., M. K.-H. Schäfer, D. Nohr, G. Ekstrom, C. Post, F. Nyberg, and E. Weihe. 1994. Spinal prodynorphin gene expression in collagen-induced arthritis, influence of the glucocorticosteroid budesonide. Neuroscience 63: 313.
    • (1994) Neuroscience , vol.63 , pp. 313
    • Persson, S.1    Schäfer, M.K.-H.2    Nohr, D.3    Ekstrom, G.4    Post, C.5    Nyberg, F.6    Weihe, E.7
  • 39
    • 0028340459 scopus 로고
    • Expression of complement C1qB and C4 mRNAs during rat brain development
    • Johnson, S. A., G. M. Pasinetti, and C. E. Finch. 1994. Expression of complement C1qB and C4 mRNAs during rat brain development. Brain Res. Dev. Brain Res. 80: 163.
    • (1994) Brain Res. Dev. Brain Res. , vol.80 , pp. 163
    • Johnson, S.A.1    Pasinetti, G.M.2    Finch, C.E.3
  • 41
    • 0030743989 scopus 로고    scopus 로고
    • Regressive changes of astroglia in white matter lesions in cerebrovascular disease and Alzheimer's disease patients
    • Tomimoto, H., I. Akiguchi, H. Wakita, T. Suenaga, S. Nakamura, and J. Kimura. 1997. Regressive changes of astroglia in white matter lesions in cerebrovascular disease and Alzheimer's disease patients. Acta Neuropathol. 94:146.
    • (1997) Acta Neuropathol. , vol.94 , pp. 146
    • Tomimoto, H.1    Akiguchi, I.2    Wakita, H.3    Suenaga, T.4    Nakamura, S.5    Kimura, J.6
  • 42
    • 0033061855 scopus 로고    scopus 로고
    • Up-regulated production and activation of the complement system in Alzheimer's disease brain
    • Yasojima, K., C. Schwab, E. G. McGeer, and P, L. McGeer. 1999. Up-regulated production and activation of the complement system in Alzheimer's disease brain. Am. J. Pathol. 154:927.
    • (1999) Am. J. Pathol. , vol.154 , pp. 927
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.