메뉴 건너뛰기




Volumn 192, Issue 2, 2005, Pages 444-462

Immune and glial cell factors as pain mediators and modulators

Author keywords

Glial cell; Immune cells; Pain

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIBIOTIC AGENT; CALCITONIN GENE RELATED PEPTIDE; CHEMOKINE; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; DIZOCILPINE; FLUOROCITRIC ACID; GALANIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1; INTERLEUKIN 1BETA; METHOTREXATE; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NONSTEROID ANTIINFLAMMATORY AGENT; PROPENTOFYLLINE; PROSTAGLANDIN SYNTHASE INHIBITOR; PURINERGIC RECEPTOR BLOCKING AGENT; SUBSTANCE P; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 14844303420     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.11.001     Document Type: Review
Times cited : (388)

References (175)
  • 1
    • 0036369587 scopus 로고    scopus 로고
    • Nerve growth factor for the treatment of diabetic neuropathy: What went wrong, what went right, and what does the future hold?
    • S.C. Apfel Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold? Int. Rev. Neurobiol. 50 2002 393 413
    • (2002) Int. Rev. Neurobiol. , vol.50 , pp. 393-413
    • Apfel, S.C.1
  • 2
    • 3042601685 scopus 로고    scopus 로고
    • Glutamate-evoked release of adenosine and regulation of peripheral nociception
    • N. Aumeerally, G. Allen, and J. Sawynok Glutamate-evoked release of adenosine and regulation of peripheral nociception Neuroscience 127 2004 1 11
    • (2004) Neuroscience , vol.127 , pp. 1-11
    • Aumeerally, N.1    Allen, G.2    Sawynok, J.3
  • 3
    • 0035144861 scopus 로고    scopus 로고
    • Neurotrophic factors: Important regulators of nociceptive function
    • D.L. Bennett Neurotrophic factors: important regulators of nociceptive function Neuroscientist 7 1 2001 13 17
    • (2001) Neuroscientist , vol.7 , Issue.1 , pp. 13-17
    • Bennett, D.L.1
  • 6
    • 0028873068 scopus 로고
    • Interleukin-6 production by Schwann cells and induction in sciatic nerve injury
    • L.M. Bolin, A.N. Verity, J.E. Silver, E.M. Shooter, and J.S. Abrams Interleukin-6 production by Schwann cells and induction in sciatic nerve injury J. Neurochem. 64 1995 850 858
    • (1995) J. Neurochem. , vol.64 , pp. 850-858
    • Bolin, L.M.1    Verity, A.N.2    Silver, J.E.3    Shooter, E.M.4    Abrams, J.S.5
  • 7
    • 0141634247 scopus 로고    scopus 로고
    • Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor
    • J.K. Bonnington, and P.A. McNaughton Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor J. Physiol. (London) 551 2003 433 446
    • (2003) J. Physiol. (London) , vol.551 , pp. 433-446
    • Bonnington, J.K.1    McNaughton, P.A.2
  • 9
    • 1542351147 scopus 로고    scopus 로고
    • Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain
    • D.C. Broom, T.A. Samad, T. Kohno, I. Tegeder, G. Geisslinger, and C.J. Woolf Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain Neuroscience 124 4 2004 891 900
    • (2004) Neuroscience , vol.124 , Issue.4 , pp. 891-900
    • Broom, D.C.1    Samad, T.A.2    Kohno, T.3    Tegeder, I.4    Geisslinger, G.5    Woolf, C.J.6
  • 10
    • 0032568417 scopus 로고    scopus 로고
    • Primary afferent tachykinins are required to experience moderate to intense pain
    • Y.Q. Cao, P.W. Mantyh, E.J. Carlson, A.M. Gillespie, C.J. Epstein, and A.I. Basbaum Primary afferent tachykinins are required to experience moderate to intense pain Nature 392 6674 1998 390 394
    • (1998) Nature , vol.392 , Issue.6674 , pp. 390-394
    • Cao, Y.Q.1    Mantyh, P.W.2    Carlson, E.J.3    Gillespie, A.M.4    Epstein, C.J.5    Basbaum, A.I.6
  • 11
    • 0028839685 scopus 로고
    • Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures
    • C.C. Chao, S. Hu, W.S. Sheng, M. Tsang, and P.K. Peterson Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures Clin. Immunol. Immunopathol. 77 3 1995 358 365
    • (1995) Clin. Immunol. Immunopathol. , vol.77 , Issue.3 , pp. 358-365
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Tsang, M.4    Peterson, P.K.5
  • 12
    • 0029087348 scopus 로고
    • Modulation of human microglial cell superoxide production by cytokines
    • C.C. Chao, S. Hu, and P.K. Peterson Modulation of human microglial cell superoxide production by cytokines J. Leukocyte Biol. 58 1 1995 65 70
    • (1995) J. Leukocyte Biol. , vol.58 , Issue.1 , pp. 65-70
    • Chao, C.C.1    Hu, S.2    Peterson, P.K.3
  • 13
    • 0029078126 scopus 로고
    • Tumor necrosis factor-alpha production by human fetal microglial cells: Regulation by other cytokines
    • C.C. Chao, S. Hu, W.S. Sheng, and P.K. Peterson Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines Dev. Neurosci. 17 2 1995 97 105
    • (1995) Dev. Neurosci. , vol.17 , Issue.2 , pp. 97-105
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Peterson, P.K.4
  • 14
    • 0035927651 scopus 로고    scopus 로고
    • Related Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns (4,5)P2-mediated inhibition
    • H.H. Chuang, E.D. Prescott, H. Kong, S. Shields, S.E. Jordt, A.I. Basbaum, M.V. Chao, and D. Julius Related Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns (4,5)P2-mediated inhibition Nature 411 6840 2001 957 962
    • (2001) Nature , vol.411 , Issue.6840 , pp. 957-962
    • Chuang, H.H.1    Prescott, E.D.2    Kong, H.3    Shields, S.4    Jordt, S.E.5    Basbaum, A.I.6    Chao, M.V.7    Julius, D.8
  • 15
    • 0030859754 scopus 로고    scopus 로고
    • Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat
    • R.W. Colburn, J.A. DeLeo, A.J. Rickman, M.P. Yeager, P. Kwon, and W.F. Hickey Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat J. Neuroimmunol. 79 2 1997 163 175
    • (1997) J. Neuroimmunol. , vol.79 , Issue.2 , pp. 163-175
    • Colburn, R.W.1    Deleo, J.A.2    Rickman, A.J.3    Yeager, M.P.4    Kwon, P.5    Hickey, W.F.6
  • 16
    • 0032978701 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior
    • R.W. Colburn, A.J. Rickman, and J.A. DeLeo The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior Exp. Neurol. 157 2 1999 289 304
    • (1999) Exp. Neurol. , vol.157 , Issue.2 , pp. 289-304
    • Colburn, R.W.1    Rickman, A.J.2    Deleo, J.A.3
  • 17
    • 0032079675 scopus 로고    scopus 로고
    • Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior
    • D.E. Coyle Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior Glia 23 1 1998 75 83
    • (1998) Glia , vol.23 , Issue.1 , pp. 75-83
    • Coyle, D.E.1
  • 18
    • 0034554778 scopus 로고    scopus 로고
    • Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons
    • T.R. Cummins, J.A. Black, S.D. Dib-Hajj, and S.G. Waxman Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons J. Neurosci. 20 23 2000 8754 8761
    • (2000) J. Neurosci. , vol.20 , Issue.23 , pp. 8754-8761
    • Cummins, T.R.1    Black, J.A.2    Dib-Hajj, S.D.3    Waxman, S.G.4
  • 19
    • 0026787367 scopus 로고
    • The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia
    • F.Q. Cunha, S. Poole, B.B. Lorenzetti, and S.H. Ferreira The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia Br. J. Pharmacol. 107 3 1992 660 664
    • (1992) Br. J. Pharmacol. , vol.107 , Issue.3 , pp. 660-664
    • Cunha, F.Q.1    Poole, S.2    Lorenzetti, B.B.3    Ferreira, S.H.4
  • 21
    • 0029783630 scopus 로고    scopus 로고
    • Interleukin-6-mediated hyperalgesia/allodynia and increased spinal IL-6 expression in a rat mononeuropathy model
    • J.A. DeLeo, R.W. Colburn, M. Nichols, and A. Malhotra Interleukin-6-mediated hyperalgesia/allodynia and increased spinal IL-6 expression in a rat mononeuropathy model J. Interferon Cytokine Res. 16 9 1996 695 700
    • (1996) J. Interferon Cytokine Res. , vol.16 , Issue.9 , pp. 695-700
    • Deleo, J.A.1    Colburn, R.W.2    Nichols, M.3    Malhotra, A.4
  • 22
    • 0030751245 scopus 로고    scopus 로고
    • Cytokine and growth factor immunohistochemical spinal profiles in two animal models of mononeuropathy
    • J.A. DeLeo, R.W. Colburn, and A.J. Rickman Cytokine and growth factor immunohistochemical spinal profiles in two animal models of mononeuropathy Brain Res. 759 1 1997 50 57
    • (1997) Brain Res. , vol.759 , Issue.1 , pp. 50-57
    • Deleo, J.A.1    Colburn, R.W.2    Rickman, A.J.3
  • 23
    • 0034532606 scopus 로고    scopus 로고
    • Effects of endogenous neurotrophins on sympathetic sprouting in the dorsal root ganglia and allodynia following spinal nerve injury
    • Y.S. Deng, J.H. Zhong, and X.F. Zhou Effects of endogenous neurotrophins on sympathetic sprouting in the dorsal root ganglia and allodynia following spinal nerve injury Exp. Neurol. 164 2 2000 344 350
    • (2000) Exp. Neurol. , vol.164 , Issue.2 , pp. 344-350
    • Deng, Y.S.1    Zhong, J.H.2    Zhou, X.F.3
  • 25
    • 0030582659 scopus 로고    scopus 로고
    • Thermal hyperalgesia in rat evoked by intrathecal substance P at multiple stimulus intensities reflects an increase in the gain of nociceptive processing
    • D.M. Dirig, and T.L. Yaksh Thermal hyperalgesia in rat evoked by intrathecal substance P at multiple stimulus intensities reflects an increase in the gain of nociceptive processing Neurosci. Lett. 220 2 1996 93 96
    • (1996) Neurosci. Lett. , vol.220 , Issue.2 , pp. 93-96
    • Dirig, D.M.1    Yaksh, T.L.2
  • 26
    • 0034463226 scopus 로고    scopus 로고
    • Spinal synthesis and release of prostanoids after peripheral injury and inflammation
    • D.M. Dirig, and T.L. Yaksh Spinal synthesis and release of prostanoids after peripheral injury and inflammation Adv. Exp. Med. Biol. 469 1999 401 408
    • (1999) Adv. Exp. Med. Biol. , vol.469 , pp. 401-408
    • Dirig, D.M.1    Yaksh, T.L.2
  • 27
    • 0032590238 scopus 로고    scopus 로고
    • The P2Z/P2X7 receptor of microglial cells: A novel immunomodulatory receptor
    • F. Di Virgilio, J.M. Sanz, P. Chiozzi, and S. Falzoni The P2Z/P2X7 receptor of microglial cells: a novel immunomodulatory receptor Prog. Brain Res. 120 1999 355 368
    • (1999) Prog. Brain Res. , vol.120 , pp. 355-368
    • Di Virgilio, F.1    Sanz, J.M.2    Chiozzi, P.3    Falzoni, S.4
  • 28
    • 0037440567 scopus 로고    scopus 로고
    • P2X7 receptor-mediated release of excitatory amino acids from astrocytes
    • S. Duan, C.M. Anderson, E.C. Keung, Y. Chen, Y. Chen, and R.A. Swanson P2X7 receptor-mediated release of excitatory amino acids from astrocytes J. Neurosci. 23 4 2003 1320 1328
    • (2003) J. Neurosci. , vol.23 , Issue.4 , pp. 1320-1328
    • Duan, S.1    Anderson, C.M.2    Keung, E.C.3    Chen, Y.4    Chen, Y.5    Swanson, R.A.6
  • 29
    • 0025132860 scopus 로고
    • Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
    • P. Ernfors, C. Wetmore, L. Olson, and H. Persson Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family Neuron 5 4 1990 511 526
    • (1990) Neuron , vol.5 , Issue.4 , pp. 511-526
    • Ernfors, P.1    Wetmore, C.2    Olson, L.3    Persson, H.4
  • 30
    • 0027399026 scopus 로고
    • Expression of mRNAs for neurotrophin receptors in the dorsal root ganglion and spinal cord during development and following peripheral or central axotomy
    • P. Ernfors, C.M. Rosario, J.P. Merlio, G. Grant, H. Aldskogius, and H. Persson Expression of mRNAs for neurotrophin receptors in the dorsal root ganglion and spinal cord during development and following peripheral or central axotomy Mol. Brain Res. 17 3-4 1993 217 226
    • (1993) Mol. Brain Res. , vol.17 , Issue.3-4 , pp. 217-226
    • Ernfors, P.1    Rosario, C.M.2    Merlio, J.P.3    Grant, G.4    Aldskogius, H.5    Persson, H.6
  • 31
    • 0031054641 scopus 로고    scopus 로고
    • Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin
    • D. Ferrari, P. Chiozzi, S. Falzoni, S. Hanau, and F. Di Virgilio Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin J. Exp. Med. 185 3 1997 579 582
    • (1997) J. Exp. Med. , vol.185 , Issue.3 , pp. 579-582
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Hanau, S.4    Di Virgilio, F.5
  • 32
    • 0033577464 scopus 로고    scopus 로고
    • Microglial reactions after subcutaneous formalin injection into the rat hind paw
    • K.Y. Fu, A.R. Light, G.K. Matsushima, and W. Maixner Microglial reactions after subcutaneous formalin injection into the rat hind paw Brain Res. 825 1-2 1999 59 67
    • (1999) Brain Res. , vol.825 , Issue.1-2 , pp. 59-67
    • Fu, K.Y.1    Light, A.R.2    Matsushima, G.K.3    Maixner, W.4
  • 33
    • 0034736219 scopus 로고    scopus 로고
    • Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin
    • K.Y. Fu, A.R. Light, and W. Maixner Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin Neuroscience 101 4 2000 1127 1135
    • (2000) Neuroscience , vol.101 , Issue.4 , pp. 1127-1135
    • Fu, K.Y.1    Light, A.R.2    Maixner, W.3
  • 34
    • 0035400009 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model
    • T. Fukuoka, E. Kondo, Y. Dai, N. Hashimoto, and K. Noguchi Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model J. Neurosci. 21 13 2001 4891 4900
    • (2001) J. Neurosci. , vol.21 , Issue.13 , pp. 4891-4900
    • Fukuoka, T.1    Kondo, E.2    Dai, Y.3    Hashimoto, N.4    Noguchi, K.5
  • 35
    • 0032960948 scopus 로고    scopus 로고
    • Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: Roles in inflammation and injury
    • R.A. Gadient, and P.H. Patterson Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury Stem Cells 17 3 1999 127 137
    • (1999) Stem Cells , vol.17 , Issue.3 , pp. 127-137
    • Gadient, R.A.1    Patterson, P.H.2
  • 36
    • 0041920806 scopus 로고    scopus 로고
    • Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat
    • S.M. Galoyan, J.C. Petruska, and L.M. Mendell Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat Eur. J. Neurosci. 18 3 2003 535 541
    • (2003) Eur. J. Neurosci. , vol.18 , Issue.3 , pp. 535-541
    • Galoyan, S.M.1    Petruska, J.C.2    Mendell, L.M.3
  • 37
    • 0036787278 scopus 로고    scopus 로고
    • Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: Regulation by nerve injury
    • N.J. Gardiner, W.B. Cafferty, S.E. Slack, and S.W. Thompson Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury J. Neurochem. 83 1 2003 100 109
    • (2003) J. Neurochem. , vol.83 , Issue.1 , pp. 100-109
    • Gardiner, N.J.1    Cafferty, W.B.2    Slack, S.E.3    Thompson, S.W.4
  • 38
    • 0027944898 scopus 로고
    • GFAP expression in lumbar spinal cord of naive and neuropathic rats treated with MK-801
    • C.J. Garrison, P.M. Dougherty, and S.M. Carlton GFAP expression in lumbar spinal cord of naive and neuropathic rats treated with MK-801 Exp. Neurol. 129 2 1994 237 243
    • (1994) Exp. Neurol. , vol.129 , Issue.2 , pp. 237-243
    • Garrison, C.J.1    Dougherty, P.M.2    Carlton, S.M.3
  • 39
    • 0032728373 scopus 로고    scopus 로고
    • Serial determination of tumor necrosis factor-alpha content in rat sciatic nerve after chronic constriction injury
    • A. George, C. Schmidt, A. Weishaupt, K.V. Toyka, and C. Sommer Serial determination of tumor necrosis factor-alpha content in rat sciatic nerve after chronic constriction injury Exp. Neurol. 160 1 1999 124 132
    • (1999) Exp. Neurol. , vol.160 , Issue.1 , pp. 124-132
    • George, A.1    Schmidt, C.2    Weishaupt, A.3    Toyka, K.V.4    Sommer, C.5
  • 40
    • 0034578906 scopus 로고    scopus 로고
    • Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin
    • A. George, M. Marziniak, M. Schafers, K.V. Toyka, and C. Sommer Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin Pain 88 3 2000 267 275
    • (2000) Pain , vol.88 , Issue.3 , pp. 267-275
    • George, A.1    Marziniak, M.2    Schafers, M.3    Toyka, K.V.4    Sommer, C.5
  • 41
    • 1642293993 scopus 로고    scopus 로고
    • Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia
    • J.R. Ghilardi, C.I. Svensson, S.D. Rogers, T.L. Yaksh, and P.W. Mantyh Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia J. Neurosci. 24 11 2004 2727 2732
    • (2004) J. Neurosci. , vol.24 , Issue.11 , pp. 2727-2732
    • Ghilardi, J.R.1    Svensson, C.I.2    Rogers, S.D.3    Yaksh, T.L.4    Mantyh, P.W.5
  • 42
    • 0030581103 scopus 로고    scopus 로고
    • DAMGO inhibits prostaglandin E2-induced potentiation of a TTX-resistant Na+ current in rat sensory neurons in vitro
    • M.S. Gold, and J.D. Levine DAMGO inhibits prostaglandin E2-induced potentiation of a TTX-resistant Na+ current in rat sensory neurons in vitro Neurosci. Lett. 212 1996 83 86
    • (1996) Neurosci. Lett. , vol.212 , pp. 83-86
    • Gold, M.S.1    Levine, J.D.2
  • 43
    • 0030199288 scopus 로고    scopus 로고
    • Activated microglia are the principal glial source of thromboxane in the central nervous system
    • D. Giulian, M. Corpuz, B. Richmond, E. Wendt, and E.R. Hall Activated microglia are the principal glial source of thromboxane in the central nervous system Neurochem. Int. 29 1 1996 65 76
    • (1996) Neurochem. Int. , vol.29 , Issue.1 , pp. 65-76
    • Giulian, D.1    Corpuz, M.2    Richmond, B.3    Wendt, E.4    Hall, E.R.5
  • 44
    • 1542373666 scopus 로고    scopus 로고
    • Microglia, macrophages, perivascular macrophages, and pericytes: A review of function and identification
    • G.J. Guillemin, and B.J. Brew Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification J. Leukocyte Biol. 75 3 2004 388 397
    • (2004) J. Leukocyte Biol. , vol.75 , Issue.3 , pp. 388-397
    • Guillemin, G.J.1    Brew, B.J.2
  • 46
    • 0034657820 scopus 로고    scopus 로고
    • Spinal glial activation and cytokine expression after lumbar root injury in the rat
    • H. Hashizume, J.A. DeLeo, R.W. Colburn, and J.N. Weinstein Spinal glial activation and cytokine expression after lumbar root injury in the rat Spine 25 10 2000 1206 1217
    • (2000) Spine , vol.25 , Issue.10 , pp. 1206-1217
    • Hashizume, H.1    Deleo, J.A.2    Colburn, R.W.3    Weinstein, J.N.4
  • 47
    • 0034255085 scopus 로고    scopus 로고
    • Central administration of methotrexate reduces mechanical allodynia in an animal model of radiculopathy/sciatica
    • H. Hashizume, M.D. Rutkowski, J.N. Weinstein, and J.A. DeLeo Central administration of methotrexate reduces mechanical allodynia in an animal model of radiculopathy/sciatica Pain 87 2 2000 159 169
    • (2000) Pain , vol.87 , Issue.2 , pp. 159-169
    • Hashizume, H.1    Rutkowski, M.D.2    Weinstein, J.N.3    Deleo, J.A.4
  • 48
    • 0026603607 scopus 로고
    • Selective inhibition of glial cell metabolism in vivo by fluorocitrate
    • B. Hassel, R.E. Paulsen, A. Johnsen, and F. Fonnum Selective inhibition of glial cell metabolism in vivo by fluorocitrate Brain Res. 576 1 1992 120 124
    • (1992) Brain Res. , vol.576 , Issue.1 , pp. 120-124
    • Hassel, B.1    Paulsen, R.E.2    Johnsen, A.3    Fonnum, F.4
  • 49
    • 0030897660 scopus 로고    scopus 로고
    • NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve
    • U. Herzberg, E. Eliav, J.M. Dorsey, R.H. Gracely, and I.J. Kopin NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve NeuroReport 8 7 1997 1613 1618
    • (1997) NeuroReport , vol.8 , Issue.7 , pp. 1613-1618
    • Herzberg, U.1    Eliav, E.2    Dorsey, J.M.3    Gracely, R.H.4    Kopin, I.J.5
  • 50
    • 0023461564 scopus 로고
    • Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages
    • R. Heumann, D. Lindholm, C. Bandtlow, M. Meyer, M.J. Radeke, T.P. Misko, E. Shooter, and H. Thoenen Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages Proc. Natl. Acad. Sci. 84 23 1987 8735 8739
    • (1987) Proc. Natl. Acad. Sci. , vol.84 , Issue.23 , pp. 8735-8739
    • Heumann, R.1    Lindholm, D.2    Bandtlow, C.3    Meyer, M.4    Radeke, M.J.5    Misko, T.P.6    Shooter, E.7    Thoenen, H.8
  • 51
    • 0033836116 scopus 로고    scopus 로고
    • Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia
    • I. Hide, M. Tanaka, A. Inoue, K. Nakajima, S. Kohsaka, K. Inoue, and Y. Nakata Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia J. Neurochem. 75 3 2000 965 972
    • (2000) J. Neurochem. , vol.75 , Issue.3 , pp. 965-972
    • Hide, I.1    Tanaka, M.2    Inoue, A.3    Nakajima, K.4    Kohsaka, S.5    Inoue, K.6    Nakata, Y.7
  • 53
    • 0033197997 scopus 로고    scopus 로고
    • Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states
    • P. Honore, P.M. Menning, S.D. Rogers, M.L. Nichols, A.I. Basbaum, J.M. Besson, and P.W. Mantyh Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states J. Neurosci. 19 17 1999 7670 7678
    • (1999) J. Neurosci. , vol.19 , Issue.17 , pp. 7670-7678
    • Honore, P.1    Menning, P.M.2    Rogers, S.D.3    Nichols, M.L.4    Basbaum, A.I.5    Besson, J.M.6    Mantyh, P.W.7
  • 54
    • 0034130227 scopus 로고    scopus 로고
    • Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
    • P. Honore, S.D. Rogers, M.J. Schwei, J.L. Salak-Johnson, N.M. Luger, M.C. Sabino, D.R. Clohisy, and P.W. Mantyh Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons Neuroscience. 98 3 2000 585 598
    • (2000) Neuroscience. , vol.98 , Issue.3 , pp. 585-598
    • Honore, P.1    Rogers, S.D.2    Schwei, M.J.3    Salak-Johnson, J.L.4    Luger, N.M.5    Sabino, M.C.6    Clohisy, D.R.7    Mantyh, P.W.8
  • 56
    • 0027265946 scopus 로고
    • Mediator release from mast cells by nerve growth factor. Neurotrophin specificity and receptor mediation
    • K. Horigome, J.C. Pryor, E.D. Bullock, and E.M. Johnson Jr. Mediator release from mast cells by nerve growth factor. Neurotrophin specificity and receptor mediation J. Biol. Chem. 268 20 1993 14881 14887
    • (1993) J. Biol. Chem. , vol.268 , Issue.20 , pp. 14881-14887
    • Horigome, K.1    Pryor, J.C.2    Bullock, E.D.3    Johnson Jr., E.M.4
  • 57
    • 0029460699 scopus 로고
    • Differential regulation by cytokines of human astrocyte nitric oxide production
    • S. Hu, W.S. Sheng, P.K. Peterson, and C.C. Chao Differential regulation by cytokines of human astrocyte nitric oxide production Glia 15 4 1995 491 494
    • (1995) Glia , vol.15 , Issue.4 , pp. 491-494
    • Hu, S.1    Sheng, W.S.2    Peterson, P.K.3    Chao, C.C.4
  • 58
    • 0033103611 scopus 로고    scopus 로고
    • Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids
    • X.Y. Hua, P. Chen, M. Marsala, and T.L. Yaksh Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids Neuroscience 89 2 1999 525 534
    • (1999) Neuroscience , vol.89 , Issue.2 , pp. 525-534
    • Hua, X.Y.1    Chen, P.2    Marsala, M.3    Yaksh, T.L.4
  • 60
    • 0242321272 scopus 로고    scopus 로고
    • Signaling of ATP receptors in glia-neuron interaction and pain
    • K. Inoue, S. Koizumi, M. Tsuda, and Y. Shigemoto-Mogami Signaling of ATP receptors in glia-neuron interaction and pain Life Sci. 74 2-3 2003 189 197
    • (2003) Life Sci. , vol.74 , Issue.2-3 , pp. 189-197
    • Inoue, K.1    Koizumi, S.2    Tsuda, M.3    Shigemoto-Mogami, Y.4
  • 62
    • 0037179755 scopus 로고    scopus 로고
    • P38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • R.R. Ji, T.A. Samad, S.X. Jin, R. Schmoll, and C.J. Woolf p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia Neuron 36 1 2002 57 68
    • (2002) Neuron , vol.36 , Issue.1 , pp. 57-68
    • Ji, R.R.1    Samad, T.A.2    Jin, S.X.3    Schmoll, R.4    Woolf, C.J.5
  • 63
    • 0037705314 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • S.X. Jin, Z.Y. Zhuang, C.J. Woolf, and R.R. Ji p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain J. Neurosci. 23 10 2003 4017 4022
    • (2003) J. Neurosci. , vol.23 , Issue.10 , pp. 4017-4022
    • Jin, S.X.1    Zhuang, Z.Y.2    Woolf, C.J.3    Ji, R.R.4
  • 64
    • 0026555556 scopus 로고
    • Formation of ion-permeable channels by tumor necrosis factor-alpha
    • B.L. Kagan, R.L. Baldwin, D. Munoz, and B.J. Wisnieski Formation of ion-permeable channels by tumor necrosis factor-alpha Science 255 5050 1992 1427 1430
    • (1992) Science , vol.255 , Issue.5050 , pp. 1427-1430
    • Kagan, B.L.1    Baldwin, R.L.2    Munoz, D.3    Wisnieski, B.J.4
  • 65
    • 0021828897 scopus 로고
    • Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus
    • R.M. Kantner, M.L. Kirby, and B.D. Goldstein Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus Brain Res. 338 1 1985 196 199
    • (1985) Brain Res. , vol.338 , Issue.1 , pp. 196-199
    • Kantner, R.M.1    Kirby, M.L.2    Goldstein, B.D.3
  • 66
    • 0037147689 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury
    • S.Y. Kim, J.C. Bae, J.Y. Kim, H.L. Lee, K.M. Lee, D.S. Kim, and H.J. Cho Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury NeuroReport 13 18 2002 2483 2486
    • (2002) NeuroReport , vol.13 , Issue.18 , pp. 2483-2486
    • Kim, S.Y.1    Bae, J.C.2    Kim, J.Y.3    Lee, H.L.4    Lee, K.M.5    Kim, D.S.6    Cho, H.J.7
  • 67
    • 0032906125 scopus 로고    scopus 로고
    • Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin
    • M. Koltzenburg, D.L. Bennett, D.L. Shelton, and S.B. McMahon Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin Eur. J. Neurosci. 11 5 1999 1698 1704
    • (1999) Eur. J. Neurosci. , vol.11 , Issue.5 , pp. 1698-1704
    • Koltzenburg, M.1    Bennett, D.L.2    Shelton, D.L.3    McMahon, S.B.4
  • 68
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • S. Kumar, J. Boehm, and J.C. Lee p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases Nat. Rev., Drug Discov. 2 9 2003 717 726
    • (2003) Nat. Rev., Drug Discov. , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 69
    • 0029880465 scopus 로고    scopus 로고
    • Up-regulation of leukaemia inhibitory factor and interleukin-6 in transected sciatic nerve and muscle following denervation
    • J.B. Kurek, L. Austin, S.S. Cheema, P.F. Bartlett, and M. Murphy Up-regulation of leukaemia inhibitory factor and interleukin-6 in transected sciatic nerve and muscle following denervation Neuromuscular Disord. 6 2 1996 105 114
    • (1996) Neuromuscular Disord. , vol.6 , Issue.2 , pp. 105-114
    • Kurek, J.B.1    Austin, L.2    Cheema, S.S.3    Bartlett, P.F.4    Murphy, M.5
  • 70
    • 0037025282 scopus 로고    scopus 로고
    • Extracellular ATP and P2X7 receptors in neurodegeneration
    • R. Le Feuvre, D. Brough, and N. Rothwell Extracellular ATP and P2X7 receptors in neurodegeneration Eur. J. Pharmacol. 447 2-3 2002 261 269
    • (2002) Eur. J. Pharmacol. , vol.447 , Issue.2-3 , pp. 261-269
    • Le Feuvre, R.1    Brough, D.2    Rothwell, N.3
  • 72
    • 0028584437 scopus 로고
    • Peripheral and central mechanisms of NGF-induced hyperalgesia
    • G.R. Lewin, A. Rueff, and L.M. Mendell Peripheral and central mechanisms of NGF-induced hyperalgesia Eur. J. Neurosci. 6 1994 1903 1912
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1903-1912
    • Lewin, G.R.1    Rueff, A.2    Mendell, L.M.3
  • 73
    • 0034660691 scopus 로고    scopus 로고
    • Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes
    • J.S. Liu, G.R. John, A. Sikora, S.C. Lee, and C.F. Brosnan Modulation of interleukin-1beta and tumor necrosis factor alpha signaling by P2 purinergic receptors in human fetal astrocytes J. Neurosci. 20 14 2000 5292 5299
    • (2000) J. Neurosci. , vol.20 , Issue.14 , pp. 5292-5299
    • Liu, J.S.1    John, G.R.2    Sikora, A.3    Lee, S.C.4    Brosnan, C.F.5
  • 74
    • 0036711470 scopus 로고    scopus 로고
    • Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus
    • W. Ma, and R. Quirion Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus Pain 99 1-2 2002 175 184
    • (2002) Pain , vol.99 , Issue.1-2 , pp. 175-184
    • Ma, W.1    Quirion, R.2
  • 75
    • 0033983432 scopus 로고    scopus 로고
    • Abnormal substance P release from the spinal cord following injury to primary sensory neurons
    • M. Malcangio, M.S. Ramer, M.G. Jones, and S.B. McMahon Abnormal substance P release from the spinal cord following injury to primary sensory neurons Eur. J. Neurosci. 12 1 2000 397 399
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.1 , pp. 397-399
    • Malcangio, M.1    Ramer, M.S.2    Jones, M.G.3    McMahon, S.B.4
  • 76
    • 0033959466 scopus 로고    scopus 로고
    • Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord
    • M. Malcangio, M.S. Ramer, T.J. Boucher, and S.B. McMahon Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord Eur. J. Neurosci. 12 1 2000 139 144
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.1 , pp. 139-144
    • Malcangio, M.1    Ramer, M.S.2    Boucher, T.J.3    McMahon, S.B.4
  • 77
    • 0028949218 scopus 로고
    • The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats
    • A.B. Malmberg, and T.L. Yaksh The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats J. Neurosci. 15 4 1995 2768 2776
    • (1995) J. Neurosci. , vol.15 , Issue.4 , pp. 2768-2776
    • Malmberg, A.B.1    Yaksh, T.L.2
  • 78
    • 0031041490 scopus 로고    scopus 로고
    • The effect of alpha-trinositol (d-myo-inositol 1,2,6-trisphosphate) on formalin-evoked spinal amino acid and prostaglandin E2 levels
    • A.B. Malmberg, T. Hedner, B. Fallgren, and N.A. Calcutt The effect of alpha-trinositol (d-myo-inositol 1,2,6-trisphosphate) on formalin-evoked spinal amino acid and prostaglandin E2 levels Brain Res. 747 1 1997 160 164
    • (1997) Brain Res. , vol.747 , Issue.1 , pp. 160-164
    • Malmberg, A.B.1    Hedner, T.2    Fallgren, B.3    Calcutt, N.A.4
  • 79
    • 0031790648 scopus 로고    scopus 로고
    • Role of IL-1 beta and TNF-alpha in the regulation of NGF in experimentally induced arthritis in mice
    • L. Manni, and L. Aloe Role of IL-1 beta and TNF-alpha in the regulation of NGF in experimentally induced arthritis in mice Rheumatol. Int. 18 3 1998 97 102
    • (1998) Rheumatol. Int. , vol.18 , Issue.3 , pp. 97-102
    • Manni, L.1    Aloe, L.2
  • 80
    • 0002139852 scopus 로고    scopus 로고
    • Trophic factors and pain
    • Churchill Livingstone
    • S.B. McMahon, and D.L.H. Bennett Trophic factors and pain Textbook of Pain 1999 Churchill Livingstone 105 128
    • (1999) Textbook of Pain , pp. 105-128
    • McMahon, S.B.1    Bennett, D.L.H.2
  • 81
    • 7444245432 scopus 로고    scopus 로고
    • Neurotrophic influences on neuropathic pain
    • Pathological Pain: From Molecular To Clinical Aspects Wiley Chichester
    • S.B. McMahon, and W.B.J. Cafferty Neurotrophic influences on neuropathic pain Pathological Pain: From Molecular To Clinical Aspects Novartis Foundation Symposium vol. 261 2004 Wiley Chichester 68 102
    • (2004) Novartis Foundation Symposium , vol.261 , pp. 68-102
    • McMahon, S.B.1    Cafferty, W.B.J.2
  • 82
    • 0029085192 scopus 로고
    • The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
    • S.B. McMahon, D.L.H. Bennett, J.V. Priestley, and D.L. Shelton The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule Nat. Med. 1 1995 774 780
    • (1995) Nat. Med. , vol.1 , pp. 774-780
    • McMahon, S.B.1    Bennett, D.L.H.2    Priestley, J.V.3    Shelton, D.L.4
  • 83
    • 0028027868 scopus 로고
    • The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
    • S.T. Meller, C. Dykstra, D. Grzybycki, S. Murphy, and G.F. Gebhart The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat Neuropharmacology 33 11 1994 1471 1478
    • (1994) Neuropharmacology , vol.33 , Issue.11 , pp. 1471-1478
    • Meller, S.T.1    Dykstra, C.2    Grzybycki, D.3    Murphy, S.4    Gebhart, G.F.5
  • 85
    • 0030776204 scopus 로고    scopus 로고
    • Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord
    • G.J. Michael, S. Averill, A. Nitkunan, M. Rattray, D.L. Bennett, Q. Yan, and J.V. Priestley Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord J. Neurosci. 17 21 1997 8476 8490
    • (1997) J. Neurosci. , vol.17 , Issue.21 , pp. 8476-8490
    • Michael, G.J.1    Averill, S.2    Nitkunan, A.3    Rattray, M.4    Bennett, D.L.5    Yan, Q.6    Priestley, J.V.7
  • 86
    • 0034615875 scopus 로고    scopus 로고
    • Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120
    • E.D. Milligan, K.K. Mehmert, J.L. Hinde, L.O. Harvey, D. Martin, K.J. Tracey, S.F. Maier, and L.R. Watkins Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120 Brain Res. 861 1 2000 105 116
    • (2000) Brain Res. , vol.861 , Issue.1 , pp. 105-116
    • Milligan, E.D.1    Mehmert, K.K.2    Hinde, J.L.3    Harvey, L.O.4    Martin, D.5    Tracey, K.J.6    Maier, S.F.7    Watkins, L.R.8
  • 89
    • 0031049658 scopus 로고    scopus 로고
    • Glial cell reactions in the spinal cord after sensory nerve stimulation are associated with axonal injury
    • C. Molander, J. Hongpaisan, M. Svensson, and H. Aldskogius Glial cell reactions in the spinal cord after sensory nerve stimulation are associated with axonal injury Brain Res. 747 1 1997 122 129
    • (1997) Brain Res. , vol.747 , Issue.1 , pp. 122-129
    • Molander, C.1    Hongpaisan, J.2    Svensson, M.3    Aldskogius, H.4
  • 90
    • 0031027332 scopus 로고    scopus 로고
    • Adult mammalian sensory and motor neurons: Roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy
    • J.B. Munson, D.L. Shelton, and S.B. McMahon Adult mammalian sensory and motor neurons: roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy J. Neurosci. 17 1997 470 476
    • (1997) J. Neurosci. , vol.17 , pp. 470-476
    • Munson, J.B.1    Shelton, D.L.2    McMahon, S.B.3
  • 91
    • 0032968705 scopus 로고    scopus 로고
    • Endogenous interleukin-6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice
    • P.G. Murphy, M.S. Ramer, L. Borthwick, J. Gauldie, P.M. Richardson, and M.A. Bisby Endogenous interleukin-6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice Eur. J. Neurosci. 11 7 1999 2243 2253
    • (1999) Eur. J. Neurosci. , vol.11 , Issue.7 , pp. 2243-2253
    • Murphy, P.G.1    Ramer, M.S.2    Borthwick, L.3    Gauldie, J.4    Richardson, P.M.5    Bisby, M.A.6
  • 92
    • 0034037553 scopus 로고    scopus 로고
    • Reciprocal actions of interleukin-6 and brain-derived neurotrophic factor on rat and mouse primary sensory neurons
    • P.G. Murphy, L.A. Borthwick, M. Altares, J. Gauldie, D. Kaplan, and P.M. Richardson Reciprocal actions of interleukin-6 and brain-derived neurotrophic factor on rat and mouse primary sensory neurons Eur. J. Neurosci. 12 6 2000 1891 1899
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.6 , pp. 1891-1899
    • Murphy, P.G.1    Borthwick, L.A.2    Altares, M.3    Gauldie, J.4    Kaplan, D.5    Richardson, P.M.6
  • 93
    • 0030248553 scopus 로고    scopus 로고
    • Reduced hyperalgesia in nerve-injured WLD mice: Relationship to nerve fiber phagocytosis, axonal degeneration, and regeneration in normal mice
    • R.R. Myers, H.M. Heckman, and M. Rodriguez Reduced hyperalgesia in nerve-injured WLD mice: relationship to nerve fiber phagocytosis, axonal degeneration, and regeneration in normal mice Exp. Neurol. 141 1 1996 94 101
    • (1996) Exp. Neurol. , vol.141 , Issue.1 , pp. 94-101
    • Myers, R.R.1    Heckman, H.M.2    Rodriguez, M.3
  • 94
    • 0030752051 scopus 로고    scopus 로고
    • Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse
    • P. Naveilhan, W.M. ElShamy, and P. Ernfors Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse Eur. J. Neurosci. 9 7 1997 1450 1460
    • (1997) Eur. J. Neurosci. , vol.9 , Issue.7 , pp. 1450-1460
    • Naveilhan, P.1    Elshamy, W.M.2    Ernfors, P.3
  • 95
    • 1642357495 scopus 로고    scopus 로고
    • MAPK activation in nociceptive neurons and pain hypersensitivity
    • K. Obata, and K. Noguchi MAPK activation in nociceptive neurons and pain hypersensitivity Life Sci. 74 21 2004 2643 2653
    • (2004) Life Sci. , vol.74 , Issue.21 , pp. 2643-2653
    • Obata, K.1    Noguchi, K.2
  • 96
    • 0037704450 scopus 로고    scopus 로고
    • Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury
    • K. Obata, H. Yamanaka, Y. Dai, T. Tachibana, T. Fukuoka, A. Tokunaga, H. Yoshikawa, and K. Noguchi Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury J. Neurosci. 23 10 2003 4117 4126
    • (2003) J. Neurosci. , vol.23 , Issue.10 , pp. 4117-4126
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Tachibana, T.4    Fukuoka, T.5    Tokunaga, A.6    Yoshikawa, H.7    Noguchi, K.8
  • 97
    • 0036794671 scopus 로고    scopus 로고
    • IL-1 beta potentiates heat-activated currents in rat sensory neurons: Involvement of IL-1RI, tyrosine kinase, and protein kinase C
    • O. Obreja, P.K. Rathee, K.S. Lips, C. Distler, and M. Kress IL-1 beta potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C FASEB J. 16 12 2002 1497 1503
    • (2002) FASEB J. , vol.16 , Issue.12 , pp. 1497-1503
    • Obreja, O.1    Rathee, P.K.2    Lips, K.S.3    Distler, C.4    Kress, M.5
  • 98
    • 0028865998 scopus 로고
    • Exogenous NT3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury
    • S. Ohara, V. Tantuwaya, P.S. DiStefano, and R.E. Schmidt Exogenous NT3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury Brain Res. 699 1 1995 143 148
    • (1995) Brain Res. , vol.699 , Issue.1 , pp. 143-148
    • Ohara, S.1    Tantuwaya, V.2    Distefano, P.S.3    Schmidt, R.E.4
  • 99
    • 0028973577 scopus 로고
    • The opposing effects of interleukin-1 beta microinjected into the preoptic hypothalamus and the ventromedial hypothalamus on nociceptive behavior in rats
    • T. Oka, K. Oka, M. Hosoi, S. Aou, and T. Hori The opposing effects of interleukin-1 beta microinjected into the preoptic hypothalamus and the ventromedial hypothalamus on nociceptive behavior in rats Brain Res. 700 1-2 1995 271 278
    • (1995) Brain Res. , vol.700 , Issue.1-2 , pp. 271-278
    • Oka, T.1    Oka, K.2    Hosoi, M.3    Aou, S.4    Hori, T.5
  • 100
    • 0029845521 scopus 로고    scopus 로고
    • Intracerebroventricular injection of tumor necrosis factor-alpha induces thermal hyperalgesia in rats
    • T. Oka, Y. Wakugawa, M. Hosoi, K. Oka, and T. Hori Intracerebroventricular injection of tumor necrosis factor-alpha induces thermal hyperalgesia in rats NeuroImmunoModulation 3 2-3 1996 135 140
    • (1996) NeuroImmunoModulation , vol.3 , Issue.2-3 , pp. 135-140
    • Oka, T.1    Wakugawa, Y.2    Hosoi, M.3    Oka, K.4    Hori, T.5
  • 101
    • 0035063934 scopus 로고    scopus 로고
    • Characterization of nociceptive responses and spinal releases of nitric oxide metabolites and glutamate evoked by different concentrations of formalin in rats
    • K. Okuda, C. Sakurada, M. Takahashi, T. Yamada, and T. Sakurada Characterization of nociceptive responses and spinal releases of nitric oxide metabolites and glutamate evoked by different concentrations of formalin in rats Pain 92 1-2 2001 07 15
    • (2001) Pain , vol.92 , Issue.1-2 , pp. 07-15
    • Okuda, K.1    Sakurada, C.2    Takahashi, M.3    Yamada, T.4    Sakurada, T.5
  • 103
    • 2442489671 scopus 로고    scopus 로고
    • TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and neurons after peripheral nerve injury: Studies in murine DRG and spinal cord
    • S. Ohtori, K. Takahashi, H. Moriya, and R.R. Myers TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord Spine 29 10 2004 1082 1088
    • (2004) Spine , vol.29 , Issue.10 , pp. 1082-1088
    • Ohtori, S.1    Takahashi, K.2    Moriya, H.3    Myers, R.R.4
  • 104
    • 0031259777 scopus 로고    scopus 로고
    • Functional characterization of substance P receptors on cultured human spinal cord astrocytes: Synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production
    • C. Palma, L. Minghetti, M. Astolfi, E. Ambrosini, F.C. Silberstein, S. Manzini, G. Levi, and F. Aloisi Functional characterization of substance P receptors on cultured human spinal cord astrocytes: synergism of substance P with cytokines in inducing interleukin-6 and prostaglandin E2 production Glia 21 2 1997 183 193
    • (1997) Glia , vol.21 , Issue.2 , pp. 183-193
    • Palma, C.1    Minghetti, L.2    Astolfi, M.3    Ambrosini, E.4    Silberstein, F.C.5    Manzini, S.6    Levi, G.7    Aloisi, F.8
  • 105
    • 0035884937 scopus 로고    scopus 로고
    • P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase
    • W. Panenka, H. Jijon, L.M. Herx, J.N. Armstrong, D. Feighan, T. Wei, V.W. Yong, R.M. Ransohoff, and B.A. MacVicar P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase J. Neurosci. 21 18 2001 7135 7142
    • (2001) J. Neurosci. , vol.21 , Issue.18 , pp. 7135-7142
    • Panenka, W.1    Jijon, H.2    Herx, L.M.3    Armstrong, J.N.4    Feighan, D.5    Wei, T.6    Yong, V.W.7    Ransohoff, R.M.8    MacVicar, B.A.9
  • 106
    • 0038143359 scopus 로고    scopus 로고
    • P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
    • L.K. Parvathenani, S. Tertyshnikova, C.R. Greco, S.B. Roberts, B. Robertson, and R. Posmantur P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease J. Biol. Chem. 278 15 2003 13309 13317
    • (2003) J. Biol. Chem. , vol.278 , Issue.15 , pp. 13309-13317
    • Parvathenani, L.K.1    Tertyshnikova, S.2    Greco, C.R.3    Roberts, S.B.4    Robertson, B.5    Posmantur, R.6
  • 107
    • 0028175982 scopus 로고
    • Interleukin-1 beta induced-desArg9bradykinin-mediated thermal hyperalgesia in the rat
    • M.N. Perkins, and D. Kelly Interleukin-1 beta induced-desArg9bradykinin- mediated thermal hyperalgesia in the rat Neuropharmacology 33 5 1994 657 660
    • (1994) Neuropharmacology , vol.33 , Issue.5 , pp. 657-660
    • Perkins, M.N.1    Kelly, D.2
  • 111
    • 0029451822 scopus 로고
    • Calcitonin gene-related peptide and ATP induce immediate early gene expression in cultured rat microglial cells
    • J. Priller, C.A. Haas, M. Reddington, and G.W. Kreutzberg Calcitonin gene-related peptide and ATP induce immediate early gene expression in cultured rat microglial cells Glia 15 4 1995 447 457
    • (1995) Glia , vol.15 , Issue.4 , pp. 447-457
    • Priller, J.1    Haas, C.A.2    Reddington, M.3    Kreutzberg, G.W.4
  • 112
    • 0032210994 scopus 로고    scopus 로고
    • Cultured astrocytes express functional receptors for galanin
    • J. Priller, C.A. Haas, M. Reddington, and G.W. Kreutzberg Cultured astrocytes express functional receptors for galanin Glia 24 3 1998 323 328
    • (1998) Glia , vol.24 , Issue.3 , pp. 323-328
    • Priller, J.1    Haas, C.A.2    Reddington, M.3    Kreutzberg, G.W.4
  • 113
    • 0030950658 scopus 로고    scopus 로고
    • Release of ATP from cultured rat astrocytes elicited by glutamate receptor activation
    • G. Queiroz, P.J. Gebicke-Haerter, A. Schobert, K. Starke, and I. von Kugelgen Release of ATP from cultured rat astrocytes elicited by glutamate receptor activation Neuroscience 78 4 1997 1203 1208
    • (1997) Neuroscience , vol.78 , Issue.4 , pp. 1203-1208
    • Queiroz, G.1    Gebicke-Haerter, P.J.2    Schobert, A.3    Starke, K.4    Von Kugelgen, I.5
  • 114
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • V. Raghavendra, F. Tanga, and J.A. DeLeo Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy J. Pharmacol. Exp. Ther. 306 2 2003 624 630
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , Issue.2 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 115
    • 0037567958 scopus 로고    scopus 로고
    • Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: Mechanistic implications of spinal glia and proinflammatory cytokines
    • V. Raghavendra, F. Tanga, M.D. Rutkowski, and J.A. DeLeo Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines Pain 104 3 2003 655 664
    • (2003) Pain , vol.104 , Issue.3 , pp. 655-664
    • Raghavendra, V.1    Tanga, F.2    Rutkowski, M.D.3    Deleo, J.A.4
  • 116
    • 3242758909 scopus 로고    scopus 로고
    • Complete Freund's adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
    • V. Raghavendra, F.Y. Tanga, and J.A. DeLeo Complete Freund's adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS Eur. J. Neurosci. 20 2 2004 467 473
    • (2004) Eur. J. Neurosci. , vol.20 , Issue.2 , pp. 467-473
    • Raghavendra, V.1    Tanga, F.Y.2    Deleo, J.A.3
  • 117
    • 0025895212 scopus 로고
    • NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration
    • G. Raivich, R. Hellweg, and G.W. Kreutzberg NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration Neuron 7 1 1991 151 164
    • (1991) Neuron , vol.7 , Issue.1 , pp. 151-164
    • Raivich, G.1    Hellweg, R.2    Kreutzberg, G.W.3
  • 118
    • 0030762694 scopus 로고    scopus 로고
    • Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRG
    • M.S. Ramer, G.D. French, and M.A. Bisby Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRG Pain 72 1-2 1997 71 78
    • (1997) Pain , vol.72 , Issue.1-2 , pp. 71-78
    • Ramer, M.S.1    French, G.D.2    Bisby, M.A.3
  • 119
    • 0031795813 scopus 로고    scopus 로고
    • Spinal nerve lesion-induced mechanoallodynia and adrenergic sprouting in sensory ganglia are attenuated in interleukin-6 knockout mice
    • M.S. Ramer, P.G. Murphy, P.M. Richardson, and M.A. Bisby Spinal nerve lesion-induced mechanoallodynia and adrenergic sprouting in sensory ganglia are attenuated in interleukin-6 knockout mice Pain 78 2 1998 115 121
    • (1998) Pain , vol.78 , Issue.2 , pp. 115-121
    • Ramer, M.S.1    Murphy, P.G.2    Richardson, P.M.3    Bisby, M.A.4
  • 120
    • 0033176025 scopus 로고    scopus 로고
    • Causes and consequences of sympathetic basket formation in dorsal root ganglia
    • M.S. Ramer, S.W. Thompson, and S.B. McMahon Causes and consequences of sympathetic basket formation in dorsal root ganglia Pain 6 1999 S111 S120
    • (1999) Pain , vol.6
    • Ramer, M.S.1    Thompson, S.W.2    McMahon, S.B.3
  • 121
    • 0036509936 scopus 로고    scopus 로고
    • Expression of functional NK-1 receptors in murine microglia
    • A. Rasley, K.L. Bost, J.K. Olson, S.D. Miller, and I. Marriott Expression of functional NK-1 receptors in murine microglia Glia 37 3 2002 258 267
    • (2002) Glia , vol.37 , Issue.3 , pp. 258-267
    • Rasley, A.1    Bost, K.L.2    Olson, J.K.3    Miller, S.D.4    Marriott, I.5
  • 122
    • 2142810261 scopus 로고    scopus 로고
    • Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia
    • A. Rasley, I. Marriott, C.R. Halberstadt, K.L. Bost, and J. Anguita Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia J. Immunol. 172 9 2004 5707 5713
    • (2004) J. Immunol. , vol.172 , Issue.9 , pp. 5707-5713
    • Rasley, A.1    Marriott, I.2    Halberstadt, C.R.3    Bost, K.L.4    Anguita, J.5
  • 123
    • 0029861749 scopus 로고    scopus 로고
    • Nerve growth factor NT5 induces increased thermal sensitivity of cutaneous nociceptors in vitro
    • A. Rueff, and L.M. Mendell Nerve growth factor NT5 induces increased thermal sensitivity of cutaneous nociceptors in vitro J. Neurophysiol. 76 1996 3593 3596
    • (1996) J. Neurophysiol. , vol.76 , pp. 3593-3596
    • Rueff, A.1    Mendell, L.M.2
  • 124
    • 0034319204 scopus 로고    scopus 로고
    • Limited role of macrophages in generation of nerve injury-induced mechanical allodynia
    • M.D. Rutkowski, J.L. Pahl, S. Sweitzer, N. van Rooijen, and J.A. DeLeo Limited role of macrophages in generation of nerve injury-induced mechanical allodynia Physiol. Behav. 71 3-4 2000 225 235
    • (2000) Physiol. Behav. , vol.71 , Issue.3-4 , pp. 225-235
    • Rutkowski, M.D.1    Pahl, J.L.2    Sweitzer, S.3    Van Rooijen, N.4    Deleo, J.A.5
  • 125
    • 0035932121 scopus 로고    scopus 로고
    • Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
    • T.A. Samad, K.A. Moore, A. Sapirstein, S. Billet, A. Allchorne, S. Poole, J.V. Bonventre, and C.J. Woolf Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity Nature 410 6827 2001 471 475
    • (2001) Nature , vol.410 , Issue.6827 , pp. 471-475
    • Samad, T.A.1    Moore, K.A.2    Sapirstein, A.3    Billet, S.4    Allchorne, A.5    Poole, S.6    Bonventre, J.V.7    Woolf, C.J.8
  • 126
    • 0035860482 scopus 로고    scopus 로고
    • Combined epineurial therapy with neutralizing antibodies to tumor necrosis factor-alpha and interleukin-1 receptor has an additive effect in reducing neuropathic pain in mice
    • M. Schafers, J. Brinkhoff, S. Neukirchen, M. Marziniak, and C. Sommer Combined epineurial therapy with neutralizing antibodies to tumor necrosis factor-alpha and interleukin-1 receptor has an additive effect in reducing neuropathic pain in mice Neurosci. Lett. 310 2001 113 116
    • (2001) Neurosci. Lett. , vol.310 , pp. 113-116
    • Schafers, M.1    Brinkhoff, J.2    Neukirchen, S.3    Marziniak, M.4    Sommer, C.5
  • 127
    • 0345701254 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons
    • M. Schafers, C.I. Svensson, C. Sommer, and L.S. Sorkin Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons J. Neurosci. 23 7 2003 2517 2521
    • (2003) J. Neurosci. , vol.23 , Issue.7 , pp. 2517-2521
    • Schafers, M.1    Svensson, C.I.2    Sommer, C.3    Sorkin, L.S.4
  • 128
    • 0346993602 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat
    • M. Schafers, M. Marziniak, L.S. Sorkin, T.L. Yaksh, and C. Sommer Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat Exp. Neurol. 185 1 2004 160 168
    • (2004) Exp. Neurol. , vol.185 , Issue.1 , pp. 160-168
    • Schafers, M.1    Marziniak, M.2    Sorkin, L.S.3    Yaksh, T.L.4    Sommer, C.5
  • 130
    • 0037092441 scopus 로고    scopus 로고
    • The cytokine network of Wallerian degeneration: Tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta
    • S. Shamash, F. Reichert, and S. Rotshenker The cytokine network of Wallerian degeneration: tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta J. Neurosci. 22 8 2002 3052 3060
    • (2002) J. Neurosci. , vol.22 , Issue.8 , pp. 3052-3060
    • Shamash, S.1    Reichert, F.2    Rotshenker, S.3
  • 131
    • 0029153012 scopus 로고
    • Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro
    • W.S. Sheng, S. Hu, F.H. Kravitz, P.K. Peterson, and C.C. Chao Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro Clin. Diagn. Lab. Immunol. 2 5 1995 604 608
    • (1995) Clin. Diagn. Lab. Immunol. , vol.2 , Issue.5 , pp. 604-608
    • Sheng, W.S.1    Hu, S.2    Kravitz, F.H.3    Peterson, P.K.4    Chao, C.C.5
  • 132
    • 0034814542 scopus 로고    scopus 로고
    • Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5
    • Y. Shigemoto-Mogami, S. Koizumi, M. Tsuda, K. Ohsawa, S. Kohsaka, and K. Inoue Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5 J. Neurochem. 78 6 2001 1339 1349
    • (2001) J. Neurochem. , vol.78 , Issue.6 , pp. 1339-1349
    • Shigemoto-Mogami, Y.1    Koizumi, S.2    Tsuda, M.3    Ohsawa, K.4    Kohsaka, S.5    Inoue, K.6
  • 133
    • 0032055877 scopus 로고    scopus 로고
    • Tackling pain at the source: New ideas about nociceptors
    • W.D. Snider, and S.B. McMahon Tackling pain at the source: new ideas about nociceptors Neuron 20 4 1998 629 632
    • (1998) Neuron , vol.20 , Issue.4 , pp. 629-632
    • Snider, W.D.1    McMahon, S.B.2
  • 134
    • 2342646193 scopus 로고    scopus 로고
    • Recent findings on how proinflammatory cytokines cause pain: Peripheral mechanisms in inflammatory and neuropathic hyperalgesia
    • C. Sommer, and M. Kress Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia Neurosci. Lett. 361 1-3 2004 184 187
    • (2004) Neurosci. Lett. , vol.361 , Issue.1-3 , pp. 184-187
    • Sommer, C.1    Kress, M.2
  • 135
    • 0030671114 scopus 로고    scopus 로고
    • A metalloprotease-inhibitor reduces pain associated behavior in mice with experimental neuropathy
    • C. Sommer, C. Schmidt, A. George, and K.V. Toyka A metalloprotease- inhibitor reduces pain associated behavior in mice with experimental neuropathy Neurosci. Lett. 237 1 1997 45 48
    • (1997) Neurosci. Lett. , vol.237 , Issue.1 , pp. 45-48
    • Sommer, C.1    Schmidt, C.2    George, A.3    Toyka, K.V.4
  • 136
    • 0032080243 scopus 로고    scopus 로고
    • Hyperalgesia in experimental neuropathy is dependent on the TNF receptor 1
    • C. Sommer, C. Schmidt, and A. George Hyperalgesia in experimental neuropathy is dependent on the TNF receptor 1 Exp. Neurol. 151 1 1998 138 142
    • (1998) Exp. Neurol. , vol.151 , Issue.1 , pp. 138-142
    • Sommer, C.1    Schmidt, C.2    George, A.3
  • 137
    • 0031884593 scopus 로고    scopus 로고
    • The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve
    • C. Sommer, M. Marziniak, and R.R. Myers The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve Pain 74 1 1998 83 91
    • (1998) Pain , vol.74 , Issue.1 , pp. 83-91
    • Sommer, C.1    Marziniak, M.2    Myers, R.R.3
  • 138
    • 0033597968 scopus 로고    scopus 로고
    • Neutralizing antibodies to interleukin 1-receptor reduce pain associated behavior in mice with experimental neuropathy
    • C. Sommer, S. Petrausch, T. Lindenlaub, and K.V. Toyka Neutralizing antibodies to interleukin 1-receptor reduce pain associated behavior in mice with experimental neuropathy Neurosci. Lett. 270 1 1999 25 28
    • (1999) Neurosci. Lett. , vol.270 , Issue.1 , pp. 25-28
    • Sommer, C.1    Petrausch, S.2    Lindenlaub, T.3    Toyka, K.V.4
  • 139
    • 0029790233 scopus 로고    scopus 로고
    • Involvement of leukemia inhibitory factor in the increases in galanin and vasoactive intestinal peptide mRNA and the decreases in neuropeptide Y and tyrosine hydroxylase mRNA in sympathetic neurons after axotomy
    • Y. Sun, and R.E. Zigmond Involvement of leukemia inhibitory factor in the increases in galanin and vasoactive intestinal peptide mRNA and the decreases in neuropeptide Y and tyrosine hydroxylase mRNA in sympathetic neurons after axotomy J. Neurochem. 67 4 1996 1751 1760
    • (1996) J. Neurochem. , vol.67 , Issue.4 , pp. 1751-1760
    • Sun, Y.1    Zigmond, R.E.2
  • 140
    • 0842322759 scopus 로고    scopus 로고
    • Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia
    • T. Suzuki, I. Hide, K. Ido, S. Kohsaka, K. Inoue, and Y. Nakata Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia J. Neurosci. 24 1 2004 1 7
    • (2004) J. Neurosci. , vol.24 , Issue.1 , pp. 1-7
    • Suzuki, T.1    Hide, I.2    Ido, K.3    Kohsaka, S.4    Inoue, K.5    Nakata, Y.6
  • 142
    • 0042267829 scopus 로고    scopus 로고
    • Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE (2) release and thermal hyperalgesia
    • C.I. Svensson, X.Y. Hua, A.A. Protter, H.C. Powell, and T.L. Yaksh Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE (2) release and thermal hyperalgesia NeuroReport 14 8 2003 1153 1157
    • (2003) NeuroReport , vol.14 , Issue.8 , pp. 1153-1157
    • Svensson, C.I.1    Hua, X.Y.2    Protter, A.A.3    Powell, H.C.4    Yaksh, T.L.5
  • 143
    • 0033594738 scopus 로고    scopus 로고
    • Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat
    • S.M. Sweitzer, R.W. Colburn, M. Rutkowski, and J.A. DeLeo Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat Brain Res. 829 1-2 1999 209 221
    • (1999) Brain Res. , vol.829 , Issue.1-2 , pp. 209-221
    • Sweitzer, S.M.1    Colburn, R.W.2    Rutkowski, M.3    Deleo, J.A.4
  • 144
    • 0035018058 scopus 로고    scopus 로고
    • Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain
    • S.M. Sweitzer, P. Schubert, and J.A. DeLeo Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain J. Pharmacol. Exp. Ther. 297 3 2001 1210 1217
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , Issue.3 , pp. 1210-1217
    • Sweitzer, S.M.1    Schubert, P.2    Deleo, J.A.3
  • 145
    • 0036228048 scopus 로고    scopus 로고
    • The differential role of spinal MHC class II and cellular adhesion molecules in peripheral inflammatory versus neuropathic pain in rodents
    • S.M. Sweitzer, K.A. White, C. Dutta, and J.A. DeLeo The differential role of spinal MHC class II and cellular adhesion molecules in peripheral inflammatory versus neuropathic pain in rodents J. Neuroimmunol. 125 1-2 2002 82 93
    • (2002) J. Neuroimmunol. , vol.125 , Issue.1-2 , pp. 82-93
    • Sweitzer, S.M.1    White, K.A.2    Dutta, C.3    Deleo, J.A.4
  • 146
    • 0030561862 scopus 로고    scopus 로고
    • Gene activation pathways of nerve growth factor signaling: A minireview
    • J. Szeberenyi Gene activation pathways of nerve growth factor signaling: a minireview Neurobiology (Budapest) 4 1-2 1996 1 11
    • (1996) Neurobiology (Budapest) , vol.4 , Issue.1-2 , pp. 1-11
    • Szeberenyi, J.1
  • 147
    • 2142768085 scopus 로고    scopus 로고
    • Effect of methylprednisolone on neuropathic pain and spinal glial activation in rats
    • K. Takeda, S. Sawamura, H. Sekiyama, H. Tamai, and K. Hanaoka Effect of methylprednisolone on neuropathic pain and spinal glial activation in rats Anesthesiology 100 5 2004 1249 1257
    • (2004) Anesthesiology , vol.100 , Issue.5 , pp. 1249-1257
    • Takeda, K.1    Sawamura, S.2    Sekiyama, H.3    Tamai, H.4    Hanaoka, K.5
  • 148
    • 0347814979 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain
    • F.Y. Tanga, V. Raghavendra, and J.A. DeLeo Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain Neurochem. Int. 45 2-3 2004 397 407
    • (2004) Neurochem. Int. , vol.45 , Issue.2-3 , pp. 397-407
    • Tanga, F.Y.1    Raghavendra, V.2    Deleo, J.A.3
  • 149
    • 0033062685 scopus 로고    scopus 로고
    • Hyperalgesia due to nerve damage: Role of nerve growth factor
    • M. Theodosiou, R.A. Rush, X.F. Zhou, D. Hu, J.S. Walker, and D.J. Tracey Hyperalgesia due to nerve damage: role of nerve growth factor Pain 81 3 1999 245 255
    • (1999) Pain , vol.81 , Issue.3 , pp. 245-255
    • Theodosiou, M.1    Rush, R.A.2    Zhou, X.F.3    Hu, D.4    Walker, J.S.5    Tracey, D.J.6
  • 150
    • 0029875155 scopus 로고
    • Leukemia inhibitory factor induces mechanical allodynia but not thermal hyperalgesia in the juvenile rat
    • S.W. Thompson, A. Dray, and L. Urban Leukemia inhibitory factor induces mechanical allodynia but not thermal hyperalgesia in the juvenile rat Neuroscience 71 4 1993 1091 1094
    • (1993) Neuroscience , vol.71 , Issue.4 , pp. 1091-1094
    • Thompson, S.W.1    Dray, A.2    Urban, L.3
  • 151
    • 0032726925 scopus 로고    scopus 로고
    • Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice
    • M. Tsuda, S. Ueno, and K. Inoue Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice Br. J. Pharmacol. 128 7 1999 1497 1504
    • (1999) Br. J. Pharmacol. , vol.128 , Issue.7 , pp. 1497-1504
    • Tsuda, M.1    Ueno, S.2    Inoue, K.3
  • 153
    • 0346655315 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury
    • M. Tsuda, A. Mizokoshi, Y. Shigemoto-Mogami, S. Koizumi, and K. Inoue Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury Glia 45 1 2004 89 95
    • (2004) Glia , vol.45 , Issue.1 , pp. 89-95
    • Tsuda, M.1    Mizokoshi, A.2    Shigemoto-Mogami, Y.3    Koizumi, S.4    Inoue, K.5
  • 154
    • 0030217998 scopus 로고    scopus 로고
    • Schwann cells produce tumor necrosis factor alpha: Expression in injured and non-injured nerves
    • R. Wagner, and R.R. Myers Schwann cells produce tumor necrosis factor
    • (1996) Neuroscience , vol.73 , Issue.3 , pp. 625-629
    • Wagner, R.1    Myers, R.R.2
  • 155
    • 0036006724 scopus 로고    scopus 로고
    • Activation of P2X (7) receptors induced [(3)H]GABA release from the RBA-2 type-2 astrocyte cell line through a Cl (-)/HCO (3) (-)-dependent mechanism
    • C.M. Wang, Y.Y. Chang, J.S. Kuo, and S.H. Sun Activation of P2X (7) receptors induced [(3)H]GABA release from the RBA-2 type-2 astrocyte cell line through a Cl (-)/HCO (3) (-)-dependent mechanism Glia 37 1 2002 8 18
    • (2002) Glia , vol.37 , Issue.1 , pp. 8-18
    • Wang, C.M.1    Chang, Y.Y.2    Kuo, J.S.3    Sun, S.H.4
  • 156
    • 0142027030 scopus 로고    scopus 로고
    • Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2
    • C.M. Wang, Y.Y. Chang, and S.H. Sun Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2 Cell Signalling 15 12 2003 1129 1137
    • (2003) Cell Signalling , vol.15 , Issue.12 , pp. 1129-1137
    • Wang, C.M.1    Chang, Y.Y.2    Sun, S.H.3
  • 158
    • 0347169249 scopus 로고    scopus 로고
    • Glia: A novel drug discovery target for clinical pain
    • L.R. Watkins, and S.F. Maier Glia: a novel drug discovery target for clinical pain Nat. Rev., Drug Discov. 2 12 2003 973 985
    • (2003) Nat. Rev., Drug Discov. , vol.2 , Issue.12 , pp. 973-985
    • Watkins, L.R.1    Maier, S.F.2
  • 159
    • 0037195594 scopus 로고    scopus 로고
    • Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: Considerations for persistent pain
    • B.A. Winkelstein, and J.A. DeLeo Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: considerations for persistent pain Brain Res. 956 2 2002 294 301
    • (2002) Brain Res. , vol.956 , Issue.2 , pp. 294-301
    • Winkelstein, B.A.1    Deleo, J.A.2
  • 160
    • 0035888084 scopus 로고    scopus 로고
    • Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment
    • B.A. Winkelstein, M.D. Rutkowski, S.M. Sweitzer, J.L. Pahl, and J.A. DeLeo Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment J. Comp. Neurol. 439 2 2001 127 139
    • (2001) J. Comp. Neurol. , vol.439 , Issue.2 , pp. 127-139
    • Winkelstein, B.A.1    Rutkowski, M.D.2    Sweitzer, S.M.3    Pahl, J.L.4    Deleo, J.A.5
  • 161
    • 0030140042 scopus 로고    scopus 로고
    • Interleukin-1beta, tumor necrosis factor-alpha, and LPS enhance calcium channel current in isolated vascular smooth muscle cells of rat tail artery
    • M.F. Wilkinson, M.L. Earle, C.R. Triggle, and S. Barnes Interleukin-1beta, tumor necrosis factor-alpha, and LPS enhance calcium channel current in isolated vascular smooth muscle cells of rat tail artery FASEB J. 10 7 1996 785 791
    • (1996) FASEB J. , vol.10 , Issue.7 , pp. 785-791
    • Wilkinson, M.F.1    Earle, M.L.2    Triggle, C.R.3    Barnes, S.4
  • 162
    • 0029981215 scopus 로고    scopus 로고
    • Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation
    • C.J. Woolf, Q.P. Ma, A. Allchorne, and S. Poole Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation J. Neurosci. 16 8 1996 2716 2723
    • (1996) J. Neurosci. , vol.16 , Issue.8 , pp. 2716-2723
    • Woolf, C.J.1    Ma, Q.P.2    Allchorne, A.3    Poole, S.4
  • 163
    • 0030913028 scopus 로고    scopus 로고
    • Cytokines, nerve growth factor and inflammatory hyperalgesia: The contribution of tumour necrosis factor alpha
    • C.J. Woolf, A. Allchorne, B. Safieh-Garabedian, and S. Poole Cytokines, nerve growth factor and inflammatory hyperalgesia: the contribution of tumour necrosis factor alpha Br. J. Pharmacol. 121 3 1997 417 424
    • (1997) Br. J. Pharmacol. , vol.121 , Issue.3 , pp. 417-424
    • Woolf, C.J.1    Allchorne, A.2    Safieh-Garabedian, B.3    Poole, S.4
  • 164
    • 0034814351 scopus 로고    scopus 로고
    • Nitric oxide synthase in spinal cord central sensitization following intradermal injection of capsaicin
    • J. Wu, L. Fang, Q. Lin, and W.D. Willis Nitric oxide synthase in spinal cord central sensitization following intradermal injection of capsaicin Pain 94 1 2001 47 58
    • (2001) Pain , vol.94 , Issue.1 , pp. 47-58
    • Wu, J.1    Fang, L.2    Lin, Q.3    Willis, W.D.4
  • 165
    • 1442323942 scopus 로고    scopus 로고
    • Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection
    • Y. Wu, H.H. Willcockson, W. Maixner, and A.R. Light Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection J. Pain 5 1 2004 48 55
    • (2004) J. Pain , vol.5 , Issue.1 , pp. 48-55
    • Wu, Y.1    Willcockson, H.H.2    Maixner, W.3    Light, A.R.4
  • 166
    • 0037184685 scopus 로고    scopus 로고
    • Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice
    • Y. Yajima, M. Narita, M. Narita, N. Matsumoto, and T. Suzuki Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice Brain Res. 958 2 2002 338 346
    • (2002) Brain Res. , vol.958 , Issue.2 , pp. 338-346
    • Yajima, Y.1    Narita, M.2    Narita, M.3    Matsumoto, N.4    Suzuki, T.5
  • 167
    • 0035882262 scopus 로고    scopus 로고
    • The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1
    • T.L. Yaksh, D.M. Dirig, C.M. Conway, C. Svensson, Z.D. Luo, and P.C. Isakson The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1 J. Neurosci. 21 16 2001 5847 5853
    • (2001) J. Neurosci. , vol.21 , Issue.16 , pp. 5847-5853
    • Yaksh, T.L.1    Dirig, D.M.2    Conway, C.M.3    Svensson, C.4    Luo, Z.D.5    Isakson, P.C.6
  • 169
    • 2342596444 scopus 로고    scopus 로고
    • Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury
    • L. Yang, P.C. Blumbergs, N.R. Jones, J. Manavis, G.T. Sarvestani, and M.N. Ghabriel Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury Spine 29 9 2004 966 971
    • (2004) Spine , vol.29 , Issue.9 , pp. 966-971
    • Yang, L.1    Blumbergs, P.C.2    Jones, N.R.3    Manavis, J.4    Sarvestani, G.T.5    Ghabriel, M.N.6
  • 170
    • 3242757516 scopus 로고    scopus 로고
    • NGF-mediated sensitization of the excitability of rat sensory neurons is prevented by a blocking antibody to the p75 neurotrophin receptor
    • Y.H. Zhang, and G.D. Nicol NGF-mediated sensitization of the excitability of rat sensory neurons is prevented by a blocking antibody to the p75 neurotrophin receptor Neurosci. Lett. 366 2 2004 187 192
    • (2004) Neurosci. Lett. , vol.366 , Issue.2 , pp. 187-192
    • Zhang, Y.H.1    Nicol, G.D.2
  • 171
    • 0037440419 scopus 로고    scopus 로고
    • Suppression of activated microglia promotes survival and function of transplanted oligodendroglial progenitors
    • S.C. Zhang, B.D. Goetz, and I.D. Duncan Suppression of activated microglia promotes survival and function of transplanted oligodendroglial progenitors Glia 41 2 2003 191 198
    • (2003) Glia , vol.41 , Issue.2 , pp. 191-198
    • Zhang, S.C.1    Goetz, B.D.2    Duncan, I.D.3
  • 172
    • 0038684167 scopus 로고    scopus 로고
    • Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
    • J. Zhang, C. Hoffert, H.K. Vu, T. Groblewski, S. Ahmad, and D. O'Donnell Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models Eur. J. Neurosci. 17 12 2003 2750 2754
    • (2003) Eur. J. Neurosci. , vol.17 , Issue.12 , pp. 2750-2754
    • Zhang, J.1    Hoffert, C.2    Vu, H.K.3    Groblewski, T.4    Ahmad, S.5    O'Donnell, D.6
  • 173
    • 0032950826 scopus 로고    scopus 로고
    • Satellite-cell-derived nerve growth factor and neurotrophin-3 are involved in noradrenergic sprouting in the dorsal root ganglia following peripheral nerve injury in the rat
    • X.F. Zhou, Y.S. Deng, E. Chie, Q. Xue, J.H. Zhong, E.M. McLachlan, R.A. Rush, and C.J. Xian Satellite-cell-derived nerve growth factor and neurotrophin-3 are involved in noradrenergic sprouting in the dorsal root ganglia following peripheral nerve injury in the rat Eur. J. Neurosci. 11 5 1999 1711 1722
    • (1999) Eur. J. Neurosci. , vol.11 , Issue.5 , pp. 1711-1722
    • Zhou, X.F.1    Deng, Y.S.2    Chie, E.3    Xue, Q.4    Zhong, J.H.5    McLachlan, E.M.6    Rush, R.A.7    Xian, C.J.8
  • 174
    • 0005002254 scopus 로고    scopus 로고
    • Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats
    • X.F. Zhou, Y.S. Deng, C.J. Xian, and J.H. Zhong Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats Eur. J. Neurosci. 12 1 2000 100 105
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.1 , pp. 100-105
    • Zhou, X.F.1    Deng, Y.S.2    Xian, C.J.3    Zhong, J.H.4
  • 175
    • 4644250844 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization
    • Z.Y. Zhuang, H. Xu, D.E. Clapham, and R.R. Ji Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization J. Neurosci. 24 38 2004 8300 8309
    • (2004) J. Neurosci. , vol.24 , Issue.38 , pp. 8300-8309
    • Zhuang, Z.Y.1    Xu, H.2    Clapham, D.E.3    Ji, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.