Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins

European Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2010, Pages 588-597

  Álvarez, Concepción ^a   Álvarez, Raquel ^a   Corchete, Purificación ^a   Pérez Melero, Concepción ^a   Peláez, Rafael ^a   Medarde, Manuel ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

2,3,4 Trimethoxyphenyl; Acetylderivatives; Antitumour; Combretastatin; Cytotoxicity; Hydrazide; Hydrazone; Indole; Oxime; Phenstatin; Tubulin

Indexed keywords

(1 ETHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANOL; (1 ETHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE; (1 ETHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE ACETYLOXIME; (1 ETHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE OXIME; (1 METHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANOL; (1 METHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE; (1 METHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE ACETYLOXIME; (1 METHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHANONE OXIME; (3 HYDROXY 4 METHOXYPHENYL)(2,3,4 TRIMETHOXYPHENYL)METHANONE; 1 ETHYL 5 [HYDRAZONO(2,3,4 TRIMETHOXYPHENYL)METHYL] 1H INDOLE; 2,3,4 TRIMETHOXY PHENYL; 5 [(2 METHYLHYDRAZONO)(2,3,4 TRIMETHOXYPHENYL)METHYL] 1 ETHYL 1H INDOLE; 5 [2 (METHYLHYDRAZONO)(2,3,4 TRIMETHOXYPHENYL)METHYL] 1 METHYL 1H INDOLE; 5 [HYDRAZONO(2,3,4 TRIMETHOXYPHENYL)METHYL] 1METHYL 1H INDOLE; ACETIC ACID DERIVATIVE; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; BENZENE DERIVATIVE; HYDRAZONE DERIVATIVE; INDOLEPHENSTATIN DERIVATIVE; N' [(1 ETHYL 1H INDOL 5 YL)(2,3,4 TRIMETHYLPHENYL) METHYLENE] ACETOHYDRAZIDE; N' [(1 METHYL 1H INDOL 5 YL)(2,3,4 TRIMETHOXYPHENYL)METHYLENE] ACETOHYDRAZIDE; OXIME DERIVATIVE; OXYGEN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; SUBSTITUTION REACTION;

ANIMALS; BENZOPHENONES; CATTLE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MITOSIS; MODELS, MOLECULAR; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 73549083623     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.10.047     Document Type: Article

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