Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 18, 2005, Pages 4048-4052

  Romagnoli, Romeo ^a   Baraldi, Pier Giovanni ^a   Jung, M Katherine ^b   Iaconinoto, Maria Antonietta ^a   Carrion, Maria Dora ^a   Remusat, Vincent ^a   Preti, Delia ^a   Tabrizi, Mojgan Aghazadeh ^a   Francesca, Fruttarolo ^a   De Clercq, Erik ^c   Balzarini, Jan ^c   Hamel, Ernest ^b  

^a UNIVERSITY OF FERRARA   (Italy)

^b NATIONAL CANCER INSTITUTE   (United States)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Anti tubulin agents; Benzoheterocycles; Combretastatin A4

Indexed keywords

ANTIMITOTIC AGENT; BENZOPHENONE DERIVATIVE; COLCHICINE; COMBRETASTATIN A4; HETEROCYCLIC COMPOUND; PHENSTATIN; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN;

ANIMALS; BENZENE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIZATION; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 23644443814     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.022     Document Type: Article

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