Arylthioindoles, potent inhibitors of tubulin polymerization

Journal of Medicinal Chemistry

Volumn 47, Issue 25, 2004, Pages 6120-6123

  De Martino, Gabriella ^a   La Regina, Giuseppe ^a   Coluccia, Antonio ^a   Edler, Michael C ^c   Barbera, Maria Chiara ^b   Brancale, Andrea ^b   Wilcox, Elizabeth ^c   Hamel, Ernest ^c   Artico, Marino ^a   Silvestri, Romano ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; COMBRETASTATIN; INDOLE DERIVATIVE; METHYL 3 [(3,4,5 TRIMETHOXYPHENYL)THIO] 5 METHOXY 1H INDOLE 2 CARBOXYLATE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CARCINOMA CELL; DRUG POTENCY; HUMAN; HUMAN CELL; IC 50; MICROTUBULE ASSEMBLY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BIOPOLYMERS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DEPRESSION, CHEMICAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; MODELS, MOLECULAR; SULFIDES; TUBULIN; TUBULIN MODULATORS;

EID: 10044236627     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049360d     Document Type: Article

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