Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents

Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2002, Pages 2556-2562

  Liou, Jing Ping ^a   Chang, Chun Wei ^a   Song, Jeng Shin ^a   Yang, Yung Ning ^a   Yeh, Ching Fang ^a   Tseng, Huan Yi ^a   Lo, Yu Kang ^a   Chang, Yi Ling ^a   Chang, Chung Ming ^a   Hsieh, Hsing Pang ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

(2 AMINO 4 METHOXYPHENYL) (3,4,5 TRIMETHOXYPHENYL)METHANONE; (2 AMINO 5 METHOXYPHENYL) (3,4,5 TRIMETHOXYPHENYL)METHANONE; ANTIMITOTIC AGENT; BENZOPHENONE DERIVATIVE; COLCHICINE; COMBRETASTATIN A4; PHENSTATIN; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BENZOPHENONES; BINDING, COMPETITIVE; BIOPOLYMERS; COLCHICINE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MITOSIS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0037030604     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010365+     Document Type: Article

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