메뉴 건너뛰기




Volumn 14, Issue 6, 2009, Pages 383-392

Blocking pro-cell-death signal pathways to conserve hearing

Author keywords

Antioxidants; Apoptosis; Cochlea; Corticosteroids; Hearing loss; JNK inhibitors

Indexed keywords

ADRENAL CORTEX HORMONES; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CYTOKINES; HAIR CELLS, AUDITORY; HEARING; HEARING LOSS; HUMANS; INFLAMMATION; ORGAN OF CORTI; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 73349097860     PISSN: 14203030     EISSN: 14219700     Source Type: Journal    
DOI: 10.1159/000241895     Document Type: Review
Times cited : (36)

References (68)
  • 1
    • 49449104088 scopus 로고    scopus 로고
    • Prevalence of hearing loss and differences by demographic characteristics among US adults: Data from the National Health and Nutrition Examination Survey, 1999-2004
    • Agrawal Y, Platz EA, Niparko JK: Prevalence of hearing loss and differences by demographic characteristics among US adults: Data from the National Health and Nutrition Examination Survey, 1999-2004. Arch Intern Med 2008; 168: 1522-1530.
    • (2008) Arch Intern Med , vol.168 , pp. 1522-1530
    • Agrawal, Y.1    Platz, E.A.2    Niparko, J.K.3
  • 4
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J: Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114: 181-190.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 5
    • 5644222552 scopus 로고    scopus 로고
    • Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
    • Muppidi JR, Tschopp J, Siegel RM: Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 2004; 21: 461-465.
    • (2004) Immunity , vol.21 , pp. 461-465
    • Muppidi, J.R.1    Tschopp, J.2    Siegel, R.M.3
  • 6
    • 16344379017 scopus 로고    scopus 로고
    • Vibration induced hearing loss in guinea pig cochlea: Expression of TNF-- and VEGF
    • Zou J, Pyykkö I, Sutinen P, Toppila E: Vibration induced hearing loss in guinea pig cochlea: Expression of TNF-- and VEGF. Hear Res 2005; 202: 13-20.
    • (2005) Hear Res , vol.202 , pp. 13-20
    • Zou, J.1    Pyykkö, I.2    Sutinen, P.3    Toppila, E.4
  • 9
    • 4544300185 scopus 로고    scopus 로고
    • The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness
    • Zine A, Van De Water TR: The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness. Curr Drug Targets CNS Neurol Disord 2004; 3: 325-332.
    • (2004) Curr Drug Targets CNS Neurol Disord , vol.3 , pp. 325-332
    • Zine, A.1    Van De Water, T.R.2
  • 11
    • 0032752178 scopus 로고    scopus 로고
    • Effect of proinflammatory cytokines on cultured spiral ligament fibrocytes
    • Yoshida K, Ichimiya I, Suzuki M, Mogi G: Effect of proinflammatory cytokines on cultured spiral ligament fibrocytes. Hear Res 1999; 137: 155-159.
    • (1999) Hear Res , vol.137 , pp. 155-159
    • Yoshida, K.1    Ichimiya, I.2    Suzuki, M.3    Mogi, G.4
  • 12
    • 0036730159 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation
    • Satoh H, Firestein GS, Billings PB, Harris JP, Keithley EM: Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope 2002; 112: 1627-1634.
    • (2002) Laryngoscope , vol.112 , pp. 1627-1634
    • Satoh, H.1    Firestein, G.S.2    Billings, P.B.3    Harris, J.P.4    Keithley, E.M.5
  • 14
    • 22644434475 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha in sensorineural hearing loss after bacterial meningitis
    • Aminpour S, Tinling SP, Brodie HA: Role of tumor necrosis factor-alpha in sensorineural hearing loss after bacterial meningitis. Otol Neurotol 2005; 26: 602-609.
    • (2005) Otol Neurotol , vol.26 , pp. 602-609
    • Aminpour, S.1    Tinling, S.P.2    Brodie, H.A.3
  • 15
    • 33750277793 scopus 로고    scopus 로고
    • Local perfusion of the tumor necrosis factor alpha blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss
    • Van Wijk F, Staecker H, Keithley E, Lefebvre PP: Local perfusion of the tumor necrosis factor alpha blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss. Audiol Neurootol 2006; 11: 357-365.
    • (2006) Audiol Neurootol , vol.11 , pp. 357-365
    • Van Wijk, F.1    Staecker, H.2    Keithley, E.3    Lefebvre, P.P.4
  • 17
    • 0042624933 scopus 로고    scopus 로고
    • Expression of adhesion molecules by cultured spiral ligament fibrocytes stimulated with proinflammatory cytokines
    • Ichimiya I, Yoshida K, Suzuki M, Mogi G: Expression of adhesion molecules by cultured spiral ligament fibrocytes stimulated with proinflammatory cytokines. Ann Otol Rhinol Laryngol 2003; 112: 722-728.
    • (2003) Ann Otol Rhinol Laryngol , vol.112 , pp. 722-728
    • Ichimiya, I.1    Yoshida, K.2    Suzuki, M.3    Mogi, G.4
  • 18
    • 16344394391 scopus 로고    scopus 로고
    • Dexamethasone inhibits tumor necrosis factor-alpha-induced cytokine secretion from spiral ligament fibrocytes
    • Maeda K, Yoshida K, Ichimiya I, Suzuki ML: Dexamethasone inhibits tumor necrosis factor-alpha-induced cytokine secretion from spiral ligament fibrocytes. Hear Res 2005; 202: 154-160.
    • (2005) Hear Res , vol.202 , pp. 154-160
    • Maeda, K.1    Yoshida, K.2    Ichimiya, I.3    Suzuki, M.L.4
  • 19
    • 56149125909 scopus 로고    scopus 로고
    • Dexamethasone protects organ of Corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes
    • Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR: Dexamethasone protects organ of Corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience 2008; 157: 405-413.
    • (2008) Neuroscience , vol.157 , pp. 405-413
    • Dinh, C.T.1    Haake, S.2    Chen, S.3    Hoang, K.4    Nong, E.5    Eshraghi, A.A.6    Balkany, T.J.7    Van De Water, T.R.8
  • 20
    • 59849087698 scopus 로고    scopus 로고
    • Biopolymer-released dexamethasone prevents tumor necrosis factor alphainduced loss of auditory hair cells in vitro: Implications toward the development of a drug-eluting cochlear implant electrode array
    • Dinh C, Hoang K, Haake S, Chen S, Angeli S, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR: Biopolymer-released dexamethasone prevents tumor necrosis factor alphainduced loss of auditory hair cells in vitro: Implications toward the development of a drug-eluting cochlear implant electrode array. Otol Neurotol 2008; 29: 1012-1019.
    • (2008) Otol Neurotol , vol.29 , pp. 1012-1019
    • Dinh, C.1    Hoang, K.2    Haake, S.3    Chen, S.4    Angeli, S.5    Nong, E.6    Eshraghi, A.A.7    Balkany, T.J.8    Van De Water, T.R.9
  • 24
    • 33750043775 scopus 로고    scopus 로고
    • Effect of steroids on increased permeability of blood vessels of the stria vascularis after auditory ossicle vibration by a drill in otologic surgery
    • Hashimoto K, Seki M, Miyasaka H, Watanabe K: Effect of steroids on increased permeability of blood vessels of the stria vascularis after auditory ossicle vibration by a drill in otologic surgery. Ann Otol Rhinol Laryngol 2006; 115: 769-774.
    • (2006) Ann Otol Rhinol Laryngol , vol.115 , pp. 769-774
    • Hashimoto, K.1    Seki, M.2    Miyasaka, H.3    Watanabe, K.4
  • 26
    • 1842557891 scopus 로고    scopus 로고
    • Protective Effect of Corticosteroid against the Cytotoxicity of Aminoglycoside Otic Drops on Isolated Cochlear Outer Hair Cells
    • DOI 10.1097/00005537-200404000-00033
    • Park SK, Choi D, Russell P, John EO, Jung TT: Protective effect of corticosteroid against the cytotoxicity of aminoglycoside otic drops on isolated cochlear outer hair cells. Laryngoscope 2004; 114: 768-771. (Pubitemid 38548795)
    • (2004) Laryngoscope , vol.114 , Issue.4 , pp. 768-771
    • Park, S.K.1    Choi, D.2    Russell, P.3    John, E.O.4    Jung, T.T.K.5
  • 27
    • 33645936636 scopus 로고    scopus 로고
    • Protective effects of glucocorticoids on ischemia-reperfusion injury of outer hair cells
    • Tabuchi K, Oikawa K, Murashita H, Hoshino T, Tsuji S, Hara A: Protective effects of glucocorticoids on ischemia-reperfusion injury of outer hair cells. Laryngoscope 2006; 116: 627-629.
    • (2006) Laryngoscope , vol.116 , pp. 627-629
    • Tabuchi, K.1    Oikawa, K.2    Murashita, H.3    Hoshino, T.4    Tsuji, S.5    Hara, A.6
  • 28
    • 34347369152 scopus 로고    scopus 로고
    • Otoprotective effects of dexamethasone in the management of pneumococcal meningitis: An animal study
    • Kim HH, Addison J, Suh E, Trune DR, Richter CP: Otoprotective effects of dexamethasone in the management of pneumococcal meningitis: An animal study. Laryngoscope 2007; 117: 1209-1215.
    • (2007) Laryngoscope , vol.117 , pp. 1209-1215
    • Kim, H.H.1    Addison, J.2    Suh, E.3    Trune, D.R.4    Richter, C.P.5
  • 29
    • 34548244171 scopus 로고    scopus 로고
    • Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss
    • Eshraghi AA, Adil E, He J, Graves R, Balkany TJ, Van De Water TR: Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss. Otol Neurotol 2007; 28: 842-849.
    • (2007) Otol Neurotol , vol.28 , pp. 842-849
    • Eshraghi, A.A.1    Adil, E.2    He, J.3    Graves, R.4    Balkany, T.J.5    Van De Water, T.R.6
  • 31
    • 34250811386 scopus 로고    scopus 로고
    • Treatment of sudden sensorineural hearing loss. I. A systematic review
    • Conlin AE, Parnes LS: Treatment of sudden sensorineural hearing loss. I. A systematic review. Arch Otolaryngol Head Neck Surg 2007; 133: 573-581.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 573-581
    • Conlin, A.E.1    Parnes, L.S.2
  • 32
    • 34250830874 scopus 로고    scopus 로고
    • Treatment of sudden sensorineural hearing loss. II. A meta-analysis
    • Conlin AE, Parnes LS: Treatment of sudden sensorineural hearing loss. II. A meta-analysis. Arch Otolaryngol Head Neck Surg 2007; 133: 582-586.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 582-586
    • Conlin, A.E.1    Parnes, L.S.2
  • 33
    • 33846099985 scopus 로고    scopus 로고
    • Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy
    • Haynes DS, O'Malley M, Cohen S, Watford K, Labadie RF: Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy. Laryngoscope 2007; 117: 3-15.
    • (2007) Laryngoscope , vol.117 , pp. 3-15
    • Haynes, D.S.1    O'Malley, M.2    Cohen, S.3    Watford, K.4    Labadie, R.F.5
  • 34
    • 58149327225 scopus 로고    scopus 로고
    • Issues, indications, and controversies regarding intratympanic steroid perfusion
    • Hamid M, Trune D: Issues, indications, and controversies regarding intratympanic steroid perfusion. Curr Opin Otolaryngol Head Neck Surg 2008; 16: 434-440.
    • (2008) Curr Opin Otolaryngol Head Neck Surg , vol.16 , pp. 434-440
    • Hamid, M.1    Trune, D.2
  • 37
    • 67849118625 scopus 로고    scopus 로고
    • Dexamethasone protects auditory hair cells against TNF--initiated apoptosis via activation of PI3K/Akt and NF- B signaling
    • E-pub ahead of print
    • Haake S, Dinh CT, Chen S, Eshraghi AA, Van De Water TR: Dexamethasone protects auditory hair cells against TNF--initiated apoptosis via activation of PI3K/Akt and NF- B signaling. Hear Res 2009, E-pub ahead of print.
    • (2009) Hear Res
    • Haake, S.1    Dinh, C.T.2    Chen, S.3    Eshraghi, A.A.4    Van De Water, T.R.5
  • 38
    • 56549091431 scopus 로고    scopus 로고
    • The complexity of mitogen-activated protein kinases (MAPKs) made simple
    • Krishna M, Narang H: The complexity of mitogen-activated protein kinases (MAPKs) made simple. Cell Mol Life Sci 2008; 65: 3525-3544.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3525-3544
    • Krishna, M.1    Narang, H.2
  • 39
    • 0141457877 scopus 로고    scopus 로고
    • A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss
    • Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel JL, Zine A: A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss. J Neurosci 2003; 23: 8596-8607.
    • (2003) J Neurosci , vol.23 , pp. 8596-8607
    • Wang, J.1    Van De Water, T.R.2    Bonny, C.3    De Ribaupierre, F.4    Puel, J.L.5    Zine, A.6
  • 40
    • 0036269755 scopus 로고    scopus 로고
    • The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
    • Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, Davis RJ: The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol 2002; 22: 4929-4942.
    • (2002) Mol Cell Biol , vol.22 , pp. 4929-4942
    • Lei, K.1    Nimnual, A.2    Zong, W.X.3    Kennedy, N.J.4    Flavell, R.A.5    Thompson, C.B.6    Bar-Sagi, D.7    Davis, R.J.8
  • 41
    • 0035152487 scopus 로고    scopus 로고
    • Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
    • Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF: Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death. Diabetes 2001; 50: 77-82.
    • (2001) Diabetes , vol.50 , pp. 77-82
    • Bonny, C.1    Oberson, A.2    Negri, S.3    Sauser, C.4    Schorderet, D.F.5
  • 43
    • 33947310957 scopus 로고    scopus 로고
    • AM-111 protects against permanent hearing loss from impulse noise trauma
    • Coleman JK, Littlesunday C, Jackson R, Meyer T: AM-111 protects against permanent hearing loss from impulse noise trauma. Hear Res 2007; 226: 70-78.
    • (2007) Hear Res , vol.226 , pp. 70-78
    • Coleman, J.K.1    Littlesunday, C.2    Jackson, R.3    Meyer, T.4
  • 45
    • 33947316135 scopus 로고    scopus 로고
    • Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity
    • Eshraghi AA, Wang J, Adil E, He J, Zine A, Bublik M, Bonny C, Puel JL, Balkany TJ, Van De Water TR: Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity. Hear Res 2007; 226: 168-177.
    • (2007) Hear Res , vol.226 , pp. 168-177
    • Eshraghi, A.A.1    Wang, J.2    Adil, E.3    He, J.4    Zine, A.5    Bublik, M.6    Bonny, C.7    Puel, J.L.8    Balkany, T.J.9    Van De Water, T.R.10
  • 47
    • 0041326612 scopus 로고    scopus 로고
    • Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase
    • Marderstein EL, Bucher B, Guo Z, Feng X, Reid K, Geller DA: Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase. Surgery 2003; 134: 280-284.
    • (2003) Surgery , vol.134 , pp. 280-284
    • Marderstein, E.L.1    Bucher, B.2    Guo, Z.3    Feng, X.4    Reid, K.5    Geller, D.A.6
  • 48
    • 5344278949 scopus 로고    scopus 로고
    • Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis
    • Minutoli L, Altavilla D, Marini H, Passaniti M, Bitto A, Seminara P, Venuti FS, Famulari C, Macrì A, Versaci A, Squadrito F: Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis. Life Sci 2004; 75: 2853-2866.
    • (2004) Life Sci , vol.75 , pp. 2853-2866
    • Minutoli, L.1    Altavilla, D.2    Marini, H.3    Passaniti, M.4    Bitto, A.5    Seminara, P.6    Venuti, F.S.7    Famulari, C.8    MacRì, A.9    Versaci, A.10    Squadrito, F.11
  • 49
    • 31344482474 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes
    • Sharma N, Suzuki H, He Q, Sharma RP: Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes. J Biochem Mol Toxicol 2005; 19: 359-367.
    • (2005) J Biochem Mol Toxicol , vol.19 , pp. 359-367
    • Sharma, N.1    Suzuki, H.2    He, Q.3    Sharma, R.P.4
  • 50
    • 33645828828 scopus 로고    scopus 로고
    • The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis
    • Assi K, Pillai R, Gómez-Muñoz A, Owen D, Salh B: The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis. Immunology 2006; 118: 112-121.
    • (2006) Immunology , vol.118 , pp. 112-121
    • Assi, K.1    Pillai, R.2    Gómez-Muñoz, A.3    Owen, D.4    Salh, B.5
  • 51
    • 42549132560 scopus 로고    scopus 로고
    • Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor
    • Kato T, Noma H, Kitagawa M, Takahashi T, Oshitani N, Kitagawa S: Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor. J Interferon Cytokine Res 2008; 28: 235-243.
    • (2008) J Interferon Cytokine Res , vol.28 , pp. 235-243
    • Kato, T.1    Noma, H.2    Kitagawa, M.3    Takahashi, T.4    Oshitani, N.5    Kitagawa, S.6
  • 52
    • 33845485903 scopus 로고    scopus 로고
    • Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model
    • Nam SI: Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model. Laryngoscope 2006; 116: 2166-2170.
    • (2006) Laryngoscope , vol.116 , pp. 2166-2170
    • Nam, S.I.1
  • 53
    • 24944482509 scopus 로고    scopus 로고
    • An NH, Kim HM: Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-kappaB on HEI-OC1 cells
    • Jeong HJ, Hong SH, Park RK, Shin T, An NH, Kim HM: Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-kappaB on HEI-OC1 cells. Hear Res 2005; 207: 59-67.
    • (2005) Hear Res , vol.207 , pp. 59-67
    • Jeong, H.J.1    Hong, S.H.2    Park, R.K.3    Shin, T.4
  • 54
    • 33744501301 scopus 로고    scopus 로고
    • The role of oxidative stress in noise-induced hearing loss
    • Henderson D, Bielefeld EC, Harris KC, Hu BH: The role of oxidative stress in noise-induced hearing loss. Ear Hear 2006; 27: 1-19.
    • (2006) Ear Hear , vol.27 , pp. 1-19
    • Henderson, D.1    Bielefeld, E.C.2    Harris, K.C.3    Hu, B.H.4
  • 55
    • 0037459786 scopus 로고    scopus 로고
    • Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea
    • Ohinata Y, Miller JM, Schacht J: Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea. Brain Res 2003; 966: 265-273.
    • (2003) Brain Res , vol.966 , pp. 265-273
    • Ohinata, Y.1    Miller, J.M.2    Schacht, J.3
  • 57
    • 0036844194 scopus 로고    scopus 로고
    • Strategies for prevention of toxicity caused by platinum-based chemotherapy: Review and summary of the annual meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 10, 2001
    • Blakley BW, Cohen JI, Doolittle ND, Muldoon LL, Campbell KC, Dickey DT, Neuwelt EA: Strategies for prevention of toxicity caused by platinum-based chemotherapy: Review and summary of the annual meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 10, 2001. Laryngoscope 2002; 112: 1997-2001.
    • (2002) Laryngoscope , vol.112 , pp. 1997-2001
    • Blakley, B.W.1    Cohen, J.I.2    Doolittle, N.D.3    Muldoon, L.L.4    Campbell, K.C.5    Dickey, D.T.6    Neuwelt, E.A.7
  • 59
    • 23944447422 scopus 로고    scopus 로고
    • Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels
    • Dickey DT, Wu YJ, Muldoon LL, Neuwelt EA: Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels. J Pharmacol Exp Ther 2005; 314: 1052-1058.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 1052-1058
    • Dickey, D.T.1    Wu, Y.J.2    Muldoon, L.L.3    Neuwelt, E.A.4
  • 60
    • 2342441227 scopus 로고    scopus 로고
    • Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity
    • Wimmer C, Mees K, Stumpf P, Welsch U, Reichel O, Suckfüll M: Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity. Otol Neurotol 2004; 25: 33-40.
    • (2004) Otol Neurotol , vol.25 , pp. 33-40
    • Wimmer, C.1    Mees, K.2    Stumpf, P.3    Welsch, U.4    Reichel, O.5    Suckfüll, M.6
  • 62
    • 0033925606 scopus 로고    scopus 로고
    • D - Methionine attenuates inner hair cell loss in carboplatin-treated chinchillas
    • Lockwood DS, Ding DL, Wang J, Salvi RJ: D - Methionine attenuates inner hair cell loss in carboplatin-treated chinchillas. Audiol Neurootol 2000; 5: 263-266.
    • (2000) Audiol Neurootol , vol.5 , pp. 263-266
    • Lockwood, D.S.1    Ding, D.L.2    Wang, J.3    Salvi, R.J.4
  • 63
    • 0036100452 scopus 로고    scopus 로고
    • D-Methionine and cisplatin ototoxicity in the guinea pig: D-methionine influences cisplatin pharmacokinetics
    • Ekborn A, Laurell G, Johnström P, Wallin I, Eksborg S, Ehrsson H: D-Methionine and cisplatin ototoxicity in the guinea pig: D-methionine influences cisplatin pharmacokinetics. Hear Res 2002; 165: 53-61.
    • (2002) Hear Res , vol.165 , pp. 53-61
    • Ekborn, A.1    Laurell, G.2    Johnström, P.3    Wallin, I.4    Eksborg, S.5    Ehrsson, H.6
  • 67
    • 2442504693 scopus 로고    scopus 로고
    • Dose and time-dependent protection of the antioxidant N-L-acetylcysteine against impulse noise trauma
    • DOI 10.1016/j.heares.2004.02.005, PII S0378595504000784
    • Duan M, Qiu J, Laurell G, Olofsson A, Counter SA, Borg E: Dose and time-dependent protection of the antioxidant N-L-acetylcysteine against impulse noise trauma. Hear Res 2004; 192: 1-9. (Pubitemid 38639826)
    • (2004) Hearing Research , vol.192 , Issue.1-2 , pp. 1-9
    • Duan, M.1    Qiu, J.2    Laurell, G.3    Olofsson, A.4    Counter, S.A.5    Borg, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.