Hypoxia-induced IL-6 production is associated with activation of MAP kinase, HIF-1, and NF-κB on HEI-OC1 cells

Hearing Research

Volumn 207, Issue 1-2, 2005, Pages 59-67

  Jeong, Hyun Ja ^a,b   Hong, Seung Heon ^b   Park, Rae Kil ^b   Shin, Taekyun ^c   An, Nyeon Hyoung ^b   Kim, Hyung Min ^a  

^a Kyung Hee University   (South Korea)

^b Wonkwang University   (South Korea)

^c Jeju National University   (South Korea)

Author keywords

Cochlear auditory cells; HIF 1 ; Hypoxia; IL 6; MAPK; NF B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; IRON; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HYPOXIA; COCHLEA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GENE REPRESSION; INNER EAR; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CELL HYPOXIA; CELL LINE; COCHLEA; DEFEROXAMINE; DNA, COMPLEMENTARY; EAR, INNER; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; RATS; RNA, MESSENGER;

EID: 24944482509     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2005.04.003     Document Type: Article

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