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Volumn 48, Issue 2, 2010, Pages 332-341

Ferroportin 1 but not hephaestin contributes to iron accumulation in a cell model of Parkinson's disease

Author keywords

6 Hydroxydopamine; Ferroportin 1; Free radicals; Hephaestin; Iron; Oxidative stress; Parkinson disease

Indexed keywords

FERROPORTIN 1; FREE RADICAL; HEPHAESTIN; IRON; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE;

EID: 72649090521     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.11.004     Document Type: Article
Times cited : (88)

References (59)
  • 1
    • 36248938279 scopus 로고    scopus 로고
    • The pathogenesis of cell death in Parkinson's disease-2007
    • Olanow C.W. The pathogenesis of cell death in Parkinson's disease-2007. Mov. Disord. 22 Suppl. 17 (2007) S335-S342
    • (2007) Mov. Disord. , vol.22 , Issue.SUPPL. 17
    • Olanow, C.W.1
  • 2
    • 34247631275 scopus 로고    scopus 로고
    • Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
    • Sulzer D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci. 30 (2007) 244-250
    • (2007) Trends Neurosci. , vol.30 , pp. 244-250
    • Sulzer, D.1
  • 3
    • 33750320296 scopus 로고    scopus 로고
    • Iron metabolism in Parkinsonian syndromes
    • Berg D., and Hochstrasser H. Iron metabolism in Parkinsonian syndromes. Mov. Disord. 21 (2006) 1299-1310
    • (2006) Mov. Disord. , vol.21 , pp. 1299-1310
    • Berg, D.1    Hochstrasser, H.2
  • 6
    • 42049123661 scopus 로고    scopus 로고
    • Midbrain iron content in early Parkinson disease: a potential biomarker of disease status
    • Martin W.R., Wieler M., and Gee M. Midbrain iron content in early Parkinson disease: a potential biomarker of disease status. Neurology 70 (2008) 1411-1417
    • (2008) Neurology , vol.70 , pp. 1411-1417
    • Martin, W.R.1    Wieler, M.2    Gee, M.3
  • 8
    • 0036113819 scopus 로고    scopus 로고
    • The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications
    • Perry G., Sayre L.M., Atwood C.S., Castellani R.J., Cash A.D., Rottkamp C.A., and Smith M.A. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. CNS Drugs 16 (2002) 339-352
    • (2002) CNS Drugs , vol.16 , pp. 339-352
    • Perry, G.1    Sayre, L.M.2    Atwood, C.S.3    Castellani, R.J.4    Cash, A.D.5    Rottkamp, C.A.6    Smith, M.A.7
  • 11
    • 0346849912 scopus 로고    scopus 로고
    • Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lesion in rats
    • Shachar D.B., Kahana N., Kampel V., Warshawsky A., and Youdim M.B. Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lesion in rats. Neuropharmacology 46 (2004) 254-263
    • (2004) Neuropharmacology , vol.46 , pp. 254-263
    • Shachar, D.B.1    Kahana, N.2    Kampel, V.3    Warshawsky, A.4    Youdim, M.B.5
  • 12
    • 26644453730 scopus 로고    scopus 로고
    • Regional distributions of manganese, iron, copper, and zinc in the brains of 6-hydroxydopamine-induced parkinsonian rats
    • Tarohda T., Ishida Y., Kawai K., Yamamoto M., and Amano R. Regional distributions of manganese, iron, copper, and zinc in the brains of 6-hydroxydopamine-induced parkinsonian rats. Anal. Bioanal. Chem. 383 (2005) 224-234
    • (2005) Anal. Bioanal. Chem. , vol.383 , pp. 224-234
    • Tarohda, T.1    Ishida, Y.2    Kawai, K.3    Yamamoto, M.4    Amano, R.5
  • 13
    • 11144304136 scopus 로고    scopus 로고
    • Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system
    • Wang J., Jiang H., and Xie J.X. Time dependent effects of 6-OHDA lesions on iron level and neuronal loss in rat nigrostriatal system. Neurochem. Res. 29 (2004) 2239-2243
    • (2004) Neurochem. Res. , vol.29 , pp. 2239-2243
    • Wang, J.1    Jiang, H.2    Xie, J.X.3
  • 14
    • 20544465100 scopus 로고    scopus 로고
    • Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration
    • Zhang X., Xie W., Qu S., Pan T., Wang X., and Le W. Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration. Biochem. Biophys. Res. Commun. 333 (2005) 544-549
    • (2005) Biochem. Biophys. Res. Commun. , vol.333 , pp. 544-549
    • Zhang, X.1    Xie, W.2    Qu, S.3    Pan, T.4    Wang, X.5    Le, W.6
  • 15
    • 36849044036 scopus 로고    scopus 로고
    • Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators
    • Zhu W., Xie W., Pan T., Xu P., Fridkin M., Zheng H., Jankovic J., Youdim M.B., and Le W. Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators. FASEB J. 21 (2007) 3835-3844
    • (2007) FASEB J. , vol.21 , pp. 3835-3844
    • Zhu, W.1    Xie, W.2    Pan, T.3    Xu, P.4    Fridkin, M.5    Zheng, H.6    Jankovic, J.7    Youdim, M.B.8    Le, W.9
  • 17
    • 0242712032 scopus 로고    scopus 로고
    • [Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice]
    • Jiang H., Qian Z.M., and Xie J.X. [Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice]. Sheng Li Xue Bao 55 (2003) 571-576
    • (2003) Sheng Li Xue Bao , vol.55 , pp. 571-576
    • Jiang, H.1    Qian, Z.M.2    Xie, J.X.3
  • 18
    • 35848961208 scopus 로고    scopus 로고
    • Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx
    • Song N., Jiang H., Wang J., and Xie J.X. Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx. J. Neurosci. Res. 85 (2007) 3118-3126
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3118-3126
    • Song, N.1    Jiang, H.2    Wang, J.3    Xie, J.X.4
  • 19
    • 40949165342 scopus 로고    scopus 로고
    • Over-expressed human divalent metal transporter 1 is involved in iron accumulation in MES23.5 cells
    • Xu H.M., Jiang H., Wang J., Luo B., and Xie J.X. Over-expressed human divalent metal transporter 1 is involved in iron accumulation in MES23.5 cells. Neurochem. Int. 52 (2008) 1044-1051
    • (2008) Neurochem. Int. , vol.52 , pp. 1044-1051
    • Xu, H.M.1    Jiang, H.2    Wang, J.3    Luo, B.4    Xie, J.X.5
  • 20
    • 67650474704 scopus 로고    scopus 로고
    • Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells
    • Zhang S., Wang J., Song N., Xie J., and Jiang H. Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells. Neurobiol. Aging 30 (2009) 1466-1476
    • (2009) Neurobiol. Aging , vol.30 , pp. 1466-1476
    • Zhang, S.1    Wang, J.2    Song, N.3    Xie, J.4    Jiang, H.5
  • 21
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • Abboud S., and Haile D.J. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J. Biol. Chem. 275 (2000) 19906-19912
    • (2000) J. Biol. Chem. , vol.275 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 24
    • 0142222530 scopus 로고    scopus 로고
    • The ceruloplasmin homolog hephaestin and the control of intestinal iron absorption
    • Anderson G.J., Frazer D.M., McKie A.T., and Vulpe C.D. The ceruloplasmin homolog hephaestin and the control of intestinal iron absorption. Blood Cells Mol. Dis. 29 (2002) 367-375
    • (2002) Blood Cells Mol. Dis. , vol.29 , pp. 367-375
    • Anderson, G.J.1    Frazer, D.M.2    McKie, A.T.3    Vulpe, C.D.4
  • 27
    • 0036972034 scopus 로고    scopus 로고
    • Distribution of ferroportin1 protein in different regions of developing rat brain
    • Jiang D.H., Ke Y., Cheng Y.Z., Ho K.P., and Qian Z.M. Distribution of ferroportin1 protein in different regions of developing rat brain. Dev. Neurosci. 24 (2002) 94-98
    • (2002) Dev. Neurosci. , vol.24 , pp. 94-98
    • Jiang, D.H.1    Ke, Y.2    Cheng, Y.Z.3    Ho, K.P.4    Qian, Z.M.5
  • 29
    • 34250014148 scopus 로고    scopus 로고
    • Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats
    • Wang J., Jiang H., and Xie J.X. Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats. Eur. J. Neurosci. 25 (2007) 2766-2772
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 2766-2772
    • Wang, J.1    Jiang, H.2    Xie, J.X.3
  • 30
    • 0026781572 scopus 로고
    • A novel N18TG2 × mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin
    • Crawford Jr. G.D., Le W.D., Smith R.G., Xie W.J., Stefani E., and Appel S.H. A novel N18TG2 × mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. J. Neurosci. 12 (1992) 3392-3398
    • (1992) J. Neurosci. , vol.12 , pp. 3392-3398
    • Crawford Jr., G.D.1    Le, W.D.2    Smith, R.G.3    Xie, W.J.4    Stefani, E.5    Appel, S.H.6
  • 31
    • 0036316947 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
    • McNaught K.S., Mytilineou C., Jnobaptiste R., Yabut J., Shashidharan P., Jennert P., and Olanow C.W. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J. Neurochem. 81 (2002) 301-306
    • (2002) J. Neurochem. , vol.81 , pp. 301-306
    • McNaught, K.S.1    Mytilineou, C.2    Jnobaptiste, R.3    Yabut, J.4    Shashidharan, P.5    Jennert, P.6    Olanow, C.W.7
  • 32
    • 0038260916 scopus 로고    scopus 로고
    • Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons
    • Pardo B., Paino C.L., Casarejos M.J., and Mena M.A. Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons. Brain Res. Brain Res. Protoc. 1 (1997) 127-132
    • (1997) Brain Res. Brain Res. Protoc. , vol.1 , pp. 127-132
    • Pardo, B.1    Paino, C.L.2    Casarejos, M.J.3    Mena, M.A.4
  • 33
    • 27244449812 scopus 로고    scopus 로고
    • Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both estrogen receptor-alpha and estrogen receptor-beta in microglia
    • Liu X., Fan X.L., Zhao Y., Luo G.R., Li X.P., Li R., and Le W.D. Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both estrogen receptor-alpha and estrogen receptor-beta in microglia. J. Neurosci. Res. 81 (2005) 653-665
    • (2005) J. Neurosci. Res. , vol.81 , pp. 653-665
    • Liu, X.1    Fan, X.L.2    Zhao, Y.3    Luo, G.R.4    Li, X.P.5    Li, R.6    Le, W.D.7
  • 34
    • 0028834446 scopus 로고
    • Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II)
    • Breuer W., Epsztejn S., and Cabantchik Z.I. Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II). J. Biol. Chem. 270 (1995) 24209-24215
    • (1995) J. Biol. Chem. , vol.270 , pp. 24209-24215
    • Breuer, W.1    Epsztejn, S.2    Cabantchik, Z.I.3
  • 35
    • 18844425714 scopus 로고    scopus 로고
    • Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis
    • Tenopoulou M., Doulias P.T., Barbouti A., Brunk U., and Galaris D. Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis. Biochem. J. 387 (2005) 703-710
    • (2005) Biochem. J. , vol.387 , pp. 703-710
    • Tenopoulou, M.1    Doulias, P.T.2    Barbouti, A.3    Brunk, U.4    Galaris, D.5
  • 36
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E., Tuttle M.S., Powelson J., Vaughn M.B., Donovan A., Ward D.M., Ganz T., and Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306 (2004) 2090-2093
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 37
    • 34447263598 scopus 로고    scopus 로고
    • Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells
    • Han O., and Kim E.Y. Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells. J. Cell. Biochem. 101 (2007) 1000-1010
    • (2007) J. Cell. Biochem. , vol.101 , pp. 1000-1010
    • Han, O.1    Kim, E.Y.2
  • 38
    • 26944441309 scopus 로고    scopus 로고
    • Cellular iron: ferroportin is the only way out
    • Ganz T. Cellular iron: ferroportin is the only way out. Cell Metab. 1 (2005) 155-157
    • (2005) Cell Metab. , vol.1 , pp. 155-157
    • Ganz, T.1
  • 42
    • 0038711587 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
    • Jeong S.Y., and David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J. Biol. Chem. 278 (2003) 27144-27148
    • (2003) J. Biol. Chem. , vol.278 , pp. 27144-27148
    • Jeong, S.Y.1    David, S.2
  • 43
    • 4644293303 scopus 로고    scopus 로고
    • Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration
    • Hahn P., Qian Y., Dentchev T., Chen L., Beard J., Harris Z.L., and Dunaief J.L. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proc. Natl. Acad. Sci. USA 101 (2004) 13850-13855
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 13850-13855
    • Hahn, P.1    Qian, Y.2    Dentchev, T.3    Chen, L.4    Beard, J.5    Harris, Z.L.6    Dunaief, J.L.7
  • 45
    • 0036283426 scopus 로고    scopus 로고
    • Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway
    • Deumens R., Blokland A., and Prickaerts J. Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp. Neurol. 175 (2002) 303-317
    • (2002) Exp. Neurol. , vol.175 , pp. 303-317
    • Deumens, R.1    Blokland, A.2    Prickaerts, J.3
  • 46
    • 40949085989 scopus 로고    scopus 로고
    • Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures
    • Kaariainen T.M., Piltonen M., Ossola B., Kekki H., Lehtonen S., Nenonen T., Lecklin A., Raasmaja A., and Mannisto P.T. Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures. Brain Res. 1203 (2008) 149-159
    • (2008) Brain Res. , vol.1203 , pp. 149-159
    • Kaariainen, T.M.1    Piltonen, M.2    Ossola, B.3    Kekki, H.4    Lehtonen, S.5    Nenonen, T.6    Lecklin, A.7    Raasmaja, A.8    Mannisto, P.T.9
  • 47
    • 36348980042 scopus 로고    scopus 로고
    • Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling
    • Weng Z., Signore A.P., Gao Y., Wang S., Zhang F., Hastings T., Yin X.M., and Chen J. Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling. J. Biol. Chem. 282 (2007) 34479-34491
    • (2007) J. Biol. Chem. , vol.282 , pp. 34479-34491
    • Weng, Z.1    Signore, A.P.2    Gao, Y.3    Wang, S.4    Zhang, F.5    Hastings, T.6    Yin, X.M.7    Chen, J.8
  • 48
    • 0242521527 scopus 로고    scopus 로고
    • The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression
    • Lymboussaki A., Pignatti E., Montosi G., Garuti C., Haile D.J., and Pietrangelo A. The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression. J. Hepatol. 39 (2003) 710-715
    • (2003) J. Hepatol. , vol.39 , pp. 710-715
    • Lymboussaki, A.1    Pignatti, E.2    Montosi, G.3    Garuti, C.4    Haile, D.J.5    Pietrangelo, A.6
  • 50
    • 27744606071 scopus 로고    scopus 로고
    • Duodenal Dcytb and hephaestin mRNA expression are not significantly modulated by variations in body iron homeostasis
    • Gleeson F., Ryan E., Barrett S., Russell J., Kelleher B., and Crowe J. Duodenal Dcytb and hephaestin mRNA expression are not significantly modulated by variations in body iron homeostasis. Blood Cells Mol. Dis. 35 (2005) 303-308
    • (2005) Blood Cells Mol. Dis. , vol.35 , pp. 303-308
    • Gleeson, F.1    Ryan, E.2    Barrett, S.3    Russell, J.4    Kelleher, B.5    Crowe, J.6
  • 51
    • 0029758487 scopus 로고    scopus 로고
    • Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
    • Hentze M.W., and Kuhn L.C. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc. Natl. Acad. Sci. USA 93 (1996) 8175-8182
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8175-8182
    • Hentze, M.W.1    Kuhn, L.C.2
  • 53
    • 33646849308 scopus 로고    scopus 로고
    • 6-Hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta
    • Hanrott K., Gudmunsen L., O'Neill M.J., and Wonnacott S. 6-Hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta. J. Biol. Chem. 281 (2006) 5373-5382
    • (2006) J. Biol. Chem. , vol.281 , pp. 5373-5382
    • Hanrott, K.1    Gudmunsen, L.2    O'Neill, M.J.3    Wonnacott, S.4
  • 54
    • 0036069457 scopus 로고    scopus 로고
    • An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells
    • Nunez-Millacura C., Tapia V., Munoz P., Maccioni R.B., and Nunez M.T. An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells. J. Neurochem. 82 (2002) 240-248
    • (2002) J. Neurochem. , vol.82 , pp. 240-248
    • Nunez-Millacura, C.1    Tapia, V.2    Munoz, P.3    Maccioni, R.B.4    Nunez, M.T.5
  • 55
    • 47149093139 scopus 로고    scopus 로고
    • Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin
    • Regan R.F., Chen M., Li Z., Zhang X., Benvenisti-Zarom L., and Chen-Roetling J. Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin. Neurobiol. Dis. 31 (2008) 242-249
    • (2008) Neurobiol. Dis. , vol.31 , pp. 242-249
    • Regan, R.F.1    Chen, M.2    Li, Z.3    Zhang, X.4    Benvenisti-Zarom, L.5    Chen-Roetling, J.6
  • 57
    • 41949087176 scopus 로고    scopus 로고
    • Zinc deficiency-induced iron accumulation, a consequence of alterations in iron regulatory protein-binding activity, iron transporters, and iron storage proteins
    • Niles B.J., Clegg M.S., Hanna L.A., Chou S.S., Momma T.Y., Hong H., and Keen C.L. Zinc deficiency-induced iron accumulation, a consequence of alterations in iron regulatory protein-binding activity, iron transporters, and iron storage proteins. J. Biol. Chem. 283 (2008) 5168-5177
    • (2008) J. Biol. Chem. , vol.283 , pp. 5168-5177
    • Niles, B.J.1    Clegg, M.S.2    Hanna, L.A.3    Chou, S.S.4    Momma, T.Y.5    Hong, H.6    Keen, C.L.7
  • 58
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease
    • Blum D., Torch S., Lambeng N., Nissou M., Benabid A.L., Sadoul R., and Verna J.M. Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog. Neurobiol. 65 (2001) 135-172
    • (2001) Prog. Neurobiol. , vol.65 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3    Nissou, M.4    Benabid, A.L.5    Sadoul, R.6    Verna, J.M.7
  • 59
    • 72649083303 scopus 로고    scopus 로고
    • Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent
    • in press;
    • Jiang, H.; Song, N.; Xu, H. M.; Zhang, S. Z.; Wang, J.; Xie, J. X. Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent. Cell Res. in press; 2009.
    • (2009) Cell Res
    • Jiang, H.1    Song, N.2    Xu, H.M.3    Zhang, S.Z.4    Wang, J.5    Xie, J.X.6


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