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Chemistry and Biodiversity

Volumn 6, Issue 11, 2009, Pages 2014-2029

Computational oral absorption simulation for low-solubility compounds

(1) Sugano, Kiyohiko a

a PFIZER GLOBAL RESEARCH AND DEVELOPMENT (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CILOSTAZOL; DANAZOL; DIPYRIDAMOLE; FELODIPINE; GEFITINIB; GRISEOFULVIN; NITRENDIPINE; PHENYTOIN; RANITIDINE; SPIRONOLACTONE;

AREA UNDER THE CURVE; BILE; CELL MEMBRANE PERMEABILITY; COMPUTER SIMULATION; CONFERENCE PAPER; DIFFUSION COEFFICIENT; DRUG ABSORPTION; DRUG DOSAGE FORM; DRUG PENETRATION; DRUG SOLUBILITY; FOOD DRUG INTERACTION; HUMAN; INTESTINE EPITHELIUM; INTESTINE TRANSIT TIME; LIPOPHILICITY; MICELLE; NONHUMAN; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; SPECIES DIFFERENCE; STOMACH EMPTYING; STOMACH PH; THEORETICAL MODEL;

ABSORPTION; ANIMALS; BILE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; MICELLES; MOUTH MUCOSA; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SOLUBILITY;

EID: 72449149167 PISSN: 16121872 EISSN: 16121880 Source Type: Journal
DOI: 10.1002/cbdv.200900101 Document Type: Conference Paper

Times cited : (44)

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