Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

International Journal of Pharmaceutics

Volumn 368, Issue 1-2, 2009, Pages 116-122

  Sugano, Kiyohiko ^a  

^a Research Formulation   (United Kingdom)

Author keywords

Bile micelles; Low solubility; Oral absorption; Simulation; Unstirred water layer

Indexed keywords

DANAZOL; MONOMER;

AREA UNDER THE CURVE; ARTICLE; BILE; CALCULATION; CELL MEMBRANE; DIET RESTRICTION; DIFFUSION; DIFFUSION COEFFICIENT; DRUG ABSORPTION; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; LIPOPHILICITY; MATHEMATICAL ANALYSIS; MICELLE; PARTITION COEFFICIENT; POSTPRANDIAL STATE; PREDICTION; PRIORITY JOURNAL; SOLUBILIZATION; THERMODYNAMICS;

ADMINISTRATION, ORAL; BILE; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHARMACEUTICAL; DANAZOL; DIFFUSION; HUMANS; INTESTINAL ABSORPTION; MICELLES; MODELS, CHEMICAL; PERMEABILITY; PREDICTIVE VALUE OF TESTS; SOLUBILITY; WATER;

EID: 58949097535     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.10.001     Document Type: Article

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