Relative bioavailability of griseofulvin lyophilized dry emulsion tablet vs. immediate release tablet: A single-dose, randomized, open-label, six-period, crossover study in healthy adult volunteers in the fasted and fed states

European Journal of Pharmaceutical Sciences

Volumn 35, Issue 3, 2008, Pages 219-225

  Ahmed, Iman Saad ^a   Aboul Einien, Mona Hassan ^a   Mohamed, Osama Hussein ^b   Farid, Samar Farghali ^a  

^a CAIRO UNIVERSITY   (Egypt)

^b UNIVERSITY OF SHARJAH   (United Arab Emirates)

Author keywords

Bioavailability; Food effects; Griseofulvin; In vivo absorption; Lyophilized dry emulsion tablets; Pharmacokinetics

Indexed keywords

GRISEOFULVIN; WATER;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; FOOD; HUMAN; HUMAN EXPERIMENT; IMMEDIATE RELEASE TABLET; IN VIVO STUDY; LYOPHILIZED DRY EMULSION TABLET; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TABLET FORMULATION;

ADMINISTRATION, ORAL; ADULT; ANTIBIOTICS, ANTIFUNGAL; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CROSS-OVER STUDIES; EMULSIONS; FASTING; FOOD-DRUG INTERACTIONS; FREEZE DRYING; GRISEOFULVIN; HUMANS; INTESTINAL ABSORPTION; MALE; POSTPRANDIAL PERIOD; POWDERS; TABLETS;

EID: 50449098704     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.07.002     Document Type: Article

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