Particle-mediated extracellular oxidative stress in the lung

Particle Toxicology

Volumn , Issue , 2006, Pages 89-117

  Kelly, Frank J ^a   Mudway, Ian S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

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EID: 72449124867     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (200)

1. Abe, S. et al., Diesel exhaust (DE)-induced cytokine expression in human bronchial epithelial cells: a study with a new cell exposure system to freshly generated DE in vitro, Am. J. Respir. Cell Mol. Biol., 22, 296, 2000.
2. Ahmed, M. N. et al., Extracellular superoxide dismutase protects lung development in hyperoxia-exposed newborn mice, Am. J. Respir. Crit. Care Med., 167, 400, 2003.
3. Ames, B. N. et al., Uric acid provides an antioxidant defense in humans against oxidant and radical caused aging and cancer: a hypothesis, Proc. Natl. Acad. Sci. U.S.A., 78, 6858, 1981.
4. Antonini, J. M. et al., Residual oil fly ash increases the susceptibility to infection and severely damages the lungs after pulmonary challenge with a bacterial pathogen, Toxicol. Sci., 70, 110, 2002.
5. Athar, M., Hasan, S. K., and Srivastava, R. C., Evidence for the involvement of hydroxyl radicals in nickel mediated enhancement of lipid peroxidation: implications for nickel carcinogenesis, Biochem. Biophys. Res. Commun., 147, 1276, 1987.
6. Aust, A. E. et al., Particle characteristics responsible for effects on human lung epithelial cells, Res. Rep. Health Eff. Inst., 110, 1, 2002.
7. Avissar, N. et al., Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells, Am. J. Physiol, 270, L173, 1996.
8. Baulig, A. et al., Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells, Am. J. Physiol. Lung Cell. Mol. Physiol, 285, L671, 2003.
9. Becker, R. F., Towards the physiological function of uric acid, Free Radic. Biol. Med., 14, 615, 1993.
10. Blomberg, A. et al., Nasal cavity lining fluid ascorbic acid concentration increases in healthy human volunteers following short term exposure to diesel exhaust, Free Radic. Res., 28, 59, 1998.
11. Bogunia-Kubik, K., Sugisaka, M., and Murray, J., From molecular biology to nanotecnology and nanomedicine, Biosystems, 65, 123, 2002.
12. Bolton, J. L. et al., Role of quinones in toxicology, Chem. Res. Toxicol., 13, 135, 2000.
13. Bonvallot, V. et al., Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression, Am. J. Respir. Cell Mol. Biol., 25, 515, 2001.
14. Borm, P. J. et al., Chronic inflammation and tumour formation in rats after intratrachial instillation of high doses of coal dusts, titanium dioxide and quartz, Inhal. Toxicol., 12, 225, 2000.
15. Brigelius-Flohe, R. and Traber, M. G., Vitamin E: function and metabolism, Faseb. J., 13, 1145, 1999.
16. Britigan, B. E., Serody, J. S., and Cohen, M. S., The role of lactoferrin as an anti-inflammatory molecule, Adv. Exp. Med. Biol., 357, 143, 1994.
17. Brown, D. M. et al., Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components, Occup. Environ. Med., 57, 685, 2000.
18. Brown, D. M. et al., Size-dependant pro-inflammatory effects of ultrafine polysteryne particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines, Toxicol. App. Pharmacol., 175, 191, 2001.
19. Brunekreef, B. and Holgate, S. T., Air pollution and health, Lancet, 360, 1233-1242, 2002.
20. Brunekreef, B. et al., Air pollution from truck traffic and lung function in children living near motorways, Epidemiology, 8, 298, 1997.
21. Buettner, G. R. and Jurkiewicz, B. A., Chemistry and biochemistry of ascorbic acid, In Handbook of Antioxidants. Cadenas, E., and Packer, L., eds., Marcel Dekker Inc., New York, 91-115, 1996.
22. Bui, M. H. et al., Dietary vitamin C intake and concentrations in the body fluids and cells of male smokers and non-smokers, J. Nutr., 122, 312, 1992.
23. Burney, P., The origins of obstructive airways disease A role for diet? Am. J. Respir. Crit. Care Med., 151, 1292, 1995.
24. Burns, D. M., Cigarettes and cigarette smoking, Clin. Chest Med., 12, 631, 1991.
25. Burton, G. W. and Ingold, K. U., Auto-oxidation of biological molecules, The antioxidant activity of vitamin E and related chain breaking phenolic antioxidants in vitro, J. Am. Chem. Soc., 103, 6472, 1981.
26. Calikoglu, M. et al., The levels of serum vitamin C, malonyldialdehyde and erythrocyte reduced glutathione in chronic obstructive pulmonary disease and in healthy smokers, Clin. Chem. Lab. Med., 40, 1028, 2002.
27. Cantin, A. M. et al., Normal alveolar epithelial lining fluid contains high levels of glutathione, J. Appl. Physiol., 63, 152, 1987.
28. Chen, R., Tunstall-Pedoe, H., and Tavendale, R., Environmental tobacco smoke and lung function in employees who never smoked: the scottish MONICA study, Occup. Environ. Med., 58, 563, 2001.
29. Chevion, M. et al., Zinc-a redox inactive-metal provides a novel approach for protection against metalmediated free radical induced injury: study of paraquat toxicity in E.coli, Adv. Exp. Med. Biol., 264, 217, 1990.
30. Church, D. F., Pryor, W. A., Free-radical chemistry of cigarette smoke and its toxicological implications. Environ. Health Perepect., 64, 111-126, 1985 Dec.
31. Cooper, B., Creeth, J. M., and Donald, A. S., Studies of the limited degradation of mucus glycoproteins. The mechanism of the peroxide reaction, Biochem. J., 228, 615, 1985.
32. Corradi, M. et al., Aldehydes in exhaled breath condensate of patients with chronic obstructive pulmonary disease, Am. J. Respir. Crit. Care Med., 167, 1380, 2003.
33. Costa, M. and Mollenhauer, H. H., Phagocytosis of nickel subsulfide particles during the early stages of neoplastic transformation in tissue culture, Cancer Res., 40, 2688, 1980.
34. Cross, C. E., Halliwell, B., and Allen, A., Antioxidant protection: a function of tracheobronchial and gastrointestinal mucus, Lancet, 8390, 1328, 1984.
35. Cross, C. E. et al., Oxidants, antioxidants, and respiratory tract lining fluids, Environ. Health Perspect., 102, 185, 1994.
36. Cross, C. E. et al., Oxidative stress and antioxidants at biosurfaces: plants, skin, and respiratory tract surfaces, Environ. Health Perspect., 106, 1241, 1998.
37. Datta, A. K. et al., Enhancement by nickel(II) and -histidine of 20-deoxyguanine oxidation with hydrogen peroxide, Carcinogenesis, 13, 283, 1992.
38. Davies, K. J. et al., Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid, Biochem. J., 235, 747, 1986.
39. Department of the Environment, London, Quality of urban air review group, The Third Report of the Quality of Urban Air Review Group, 37, 1996.
40. Diliberto, E. J. Jr., et al., Tissue, subcellular, and submitochondrial distributions of semidehydroascorbate reductase: possible role of semidehydroascorbate reductase in cofactor regeneration, J. Neurochem., 39, 563, 1982.
41. Doba, T., Burton, G. W., and Ingold, K. U., The effect of vitamin C, either alone or in the presence of vitamin E or a water soluble vitamin C analogue, upon the peroxidation of aqueous multilamellar phospholipids liposomes, Biochem. Biophys. Acta, 835, 298, 1985.
42. Dockery, D. W. et al., An association between air pollution and mortality in six U.S. cities, N. Engl. J. Med., 329, 1753, 1993.
43. Doelman, C. J. and Bast, A., Pro- and anti-oxidant factors in rat lung cytosol, Adv. Exp. Med. Biol., 264, 455, 1990.
44. Donaldson, K. and Tran, C. L., Inflammation caused by particles and fibers, Inhal. Toxicol., 14, 5, 2002.
45. Donaldson, K. and Tran, C. L., An introduction to the short-term toxicology of respirable industrial fibers, Mutat. Res., 553, 5, 2004.
46. Donaldson, K. et al., Asbestos-stimulated tumour necrosis factor release from alveolar macrophages depends on fiber length and opsonization, J. Pathol., 168, 243, 1992.
47. Dreher, K. L. et al., Soluble transition metals mediate residual oil fly ash induced acute lung injury, J. Toxicol. Environ. Health, 50, 285, 1997.
48. Driscoll, K. E., Role of inflammation in the development of rat tumors in response to chronic particle exposure, Inhal. Toxicol., 8, 139, 1996.
49. Droge, W., Free radicals in the physiological control of cell function, Physiol. Rev., 82, 47, 2002.
50. Duffin, R. et al., The importance of surface area and specific reactivity in the acute pulmonary inflammatory response to particles, Ann. Occup. Hyg., 46, 242, 2002.
51. Duggan, S. et al., Particulate matter in London air is highly oxidising, implying a significant potential risk to respiratory health, Eur. Respir. J., 20, 260, 2002.
52. Duggan, S. et al., Transition metal rich particulate matter can subvert the endogenous defenses within the respiratory tract lining fluid, Am. J. Respir. Crit. Care Med, 167, A973, 2003.
53. Elsayed, N. M., Antioxidant mobilization in response to oxidative stress: a dynamic environmental-nutritional interaction, Nutrition, 10, 828, 2001.
54. Exley, C., The pro-oxidant activity of aluminium, Free Radic. Biol. Med., 36, 380, 2003.
55. Ferin, J., Oberdörster, G., and Penney, D. P., Pulmonary retention of ultrafine and fine particles in rats, Am. J. Respir. Cell Mol. Biol., 6, 535, 1992.
56. Freeman, B. A. and Crapo, J. D., Biology of disease: free radicals and tissue injury, Lab. Invest., 47, 412, 1982.
57. Fridovich, I., Oxygen toxicity: a radical explanation, J. Exp. Biol., 201, 1203, 1998.
58. Fryer, A. A. et al., Polymorphism at the glutathione S-transferase GSTP1 locus: a new marker for bronchial hyperresponsiveness and asthma, Am. J. Respir. Crit. Care Med., 161, 1437, 2000.
59. Fubini, B., Surface reactivity in the pathogenic response to particulates, Environ. Health Perspect., 105, 1013, 1997.
60. Galaris, D. and Evangelou, A., The role of oxidative stress in mechanisms of metal-induced carcinogenesis, Crit. Rev. Oncol. Hematol., 42, 93, 2002.
61. Gallagher, J. et al., Formation of 8-oxo-7,8-dihydro-20-deoxyguanosine in rat lung DNA following subchronic inhalation of carbon black, Toxicol. Appl. Pharmacol., 190, 224, 2003.
62. Gamble, J., Jones, W., and Minshall, S., Epidemiological-environmental study of diesel bus garage workers: chronic effects of diesel exhaust on the respiratory system, Environ. Res., 44, 6, 1987.
63. Gavett, S. H. et al., Metal and sulfate composition of residual oil fly ash determines airway hyperreactivity and lung injury in rats, Environ. Res., 72, 162, 1997.
64. Ghio, A. J., Kim, C., and Devlin, R. B., Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers, Am. J. Respir. Crit. Care Med., 162, 981, 2000.
65. Ghio, A. J. et al., Complexation of iron cation by sodium urate crystals and gouty inflammation, Arch. Biochem. Biophys., 313, 215, 1994.
66. Ghio, A. J. et al., Iron regulates xanthine oxidase activity in the lung, Am. J. Physiol. Lung Cell. Mol. Physiol, 283, L563, 2002.
67. Ghio, A. J. et al., Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash, Am. J. Physiol. Lung Cell. Mol. Physiol., 283, L211, 2002a.
68. Gilliland, F. D. et al., A theoretical basis for investigating ambient air pollution and children’s respiratory health, Environ. Health Perspect., 107, 403, 1999.
69. Gilliland, F. D. et al., Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study, Lancet, 363, 119, 2004.
70. Gilmour, P. S. et al., Detection of surface free-radical activity of respirable industrial fibers using supercoiled phi-x174 rf1 plasmid DNA, Carcinogenesis, 16, 2973, 1995.
71. Gilmour, P. S. et al., Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles, Toxicol. Appl. Pharmacol., 195, 35, 2004.
72. Gong, H., Sioutas, C., and Linn, W. S., Controlled exposures of healthy and asthmatic volunteers to concentrated ambient particles in metropolitan Los Angeles, Res. Rep. Health Eff. Inst., 1, 37, 2003.
73. Gurer, H. and Ercal, N., Can antioxidants be beneficial in the treatment of lead poisoning? Free Rad. Biol. Med., 10, 927, 2000.
74. Gurgueira, S. A. et al., Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation, Environ. Health Perspect., 110, 749, 2002.
75. Halliwell, B. and Gutteridge, J. M., Biologically relevant metal ion-dependent hydroxyl radical generation. An update, FEBS Lett., 307, 108, 1992.
76. Halliwell, B. and Gutteridge, J. M. C., Free Radic. Biol. Med., Clarendon Press, Oxford, 1999.
77. Han, J. Y., Takeshita, K., and Utsumi, H., Noninvasive detection of hydroxyl radical generation in lung by diesel exhaust particles, Free Radic. Biol. Med., 30, 516, 2001.
78. Hashimoto, S. et al., Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation, Am. J. Respir. Crit Care Med., 161, 280, 2000.
79. Haslam, P. L. and Baughman, R. P., Report of ERS task force: guidelines for measurement of acellular components and standardization of BAL, Eur. Respir. J., 14, 245, 1999.
80. Heinrich, U. et al., Chronic inhalation of wistar rats and two different strains of mice to diesel exhaust, carbon black and titanium dioxide, Inhal. Toxicol., 7, 533, 1995.
81. Herrero, M. C. et al., Nickel effects on hepatic amino acids, Res. Commun. Chem. Pathol. Pharmacol., 79, 243, 1993.
82. Hiraishi, H. et al., Role for mucous glycoprotein in protecting cultured rat gastric mucosal cells against toxic oxygen metabolites, J. Lab. Clin. Med., 121, 570, 1993.
83. Hirvonen, A., Polymorphism of xenobiotic-metabolizing enzymes and susceptibility to cancer, Environ. Health Perspect., 107, 37, 1999.
84. Housley, D. G., Eccles, R., and Richards, R. J., Gender difference in the concentration of the antioxidant uric acid in human nasal lavage, Acta Otolaryngol. (Stockh), 116, 751, 1996.
85. Huang, X., Klein, C. B., and Costa, M., Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein, Carcinogenesis, 15, 545, 1994.
86. Huang, X. et al., The role of nickel and nickel-mediated reactive oxygen species in the mechanism of nickel carcinogenesis, Environ. Health Perspect., 102, 281, 1994.
87. Hunt, J. F. et al., Endogenous airway acidification. Implications for asthma pathophysiology, Am. J. Respir. Crit. Care Med., 161, 694, 2000.
88. Ichinose, T. A. et al., Biological effects of diesel exhaust particles (DEP). II. Acute toxicity of DEP introduced into lung by intratracheal instillation, Toxicology, 99, 153, 1985.
89. Jenkinson, S. G., Black, R. D., and Lawrence, R. A., Glutathione concentrations in rat lung bronchoalveolar lavage fluid: effect of hyperoxia, J. Lab. Clin. Med., 112, 345, 1988.
90. Kadiiska, M. B. et al., In vivo evidence of free radical formation in the rat lung after exposure to an emission source air pollution particle, Chem. Res. Toxicol., 10, 1104, 1997.
91. Kane, A. B., Mechanisms of mineral fiber carcinogenesis, In Mechanisms of Fiber Carcinogenesis, Kane, A. B., Boffetta, P., Saracci, R., Wilbourn, J. D., eds., IARC Scientific Publications, No 140, International Agency for Research on Cancer, Lyon, 11, 1996.
92. Kasprzak, K. S., The role of oxidative damage in metal carcinogenesis, Chem. Res. Toxicol., 4, 604, 1991.
93. Kawasaki, S. et al., Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells, Am. J. Respir. Cell Mol. Biol., 24, 419, 2001.
94. Kelly, F. J., Oxidative stress; its role in air pollution and adverse health effects, Occup. Environ. Med., 60, 612, 2003.
95. Kelly, F. J. and Richards, R., Antioxidant defenses in the human lung, In Air Pollution and Health, Holgate, S., Samet, J., Koren, H. S., and Maynard, R. L., eds., Academic Press, New York, 1999.
96. Kelly, F. J., Buhl, R., and Sandström, T., Measurement of antioxidants, oxidants and oxidant products in bronchoalveolar lavage fluid, Eur. Respir. Rev., 9, 93, 1999.
97. Kelly, F. J. et al., The free radical basis of air pollution: focus on ozone, Respir. Med., 89, 647, 1995.
98. Kelly, F. J. et al., Altered lung antioxidant status in patients with mild asthma, Lancet, 354, 482, 1999.
99. Klein, C. B., Frenkel, K., and Costa, M., The role of oxidative processes in metal carcinogenesis, Chem. Res. Toxicol., 4, 592, 1991.
100. Koc, M. et al., Levels of some acute-phase proteins in the serum of patients with cancer during radiotherapy, Biol. Pharm. Bull., 26, 1494, 2003.
101. Kodavanti, U. P. et al., Acute lung injury from intratracheal exposure to fugitive residual oil fly ash and its constituent metals in normo- and spontaneously hypertensive rats, Inhal. Toxicol., 13, 37, 2001.
102. Kumagai, Y. et al., Oxidation of proximal protein sulfhydryls by phenanthraquinone, a component of diesel exhaust particles, Chem, Res. Toxicol., 15, 483, 2002.
103. Lawton, L. J. and Donaldson, W., Lead-induced tissue fatty acid alterations and lipid peroxidation, Biol. Trace Elem. Res., 28, 83, 1991.
104. Lee, K. P., Trochimowicz, H. J., and Reinhardt, C. F., Pulmonary response of rats exposed to titanium dioxide (TiO2) by inhalation for two years, Toxicol. Appl. Pharmacol., 79, 179, 1985.
105. Li, N. et al., Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter, Inhal. Toxicol., 14, 459, 2002.
106. Li, W., Zhao, Y., and Chou, I. N., Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions, Toxicology, 77, 65, 1993.
107. Li, X. Y. et al., Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro, Thorax, 51, 1216, 1996.
108. Li, X. Y. et al., Short-term inflammatory responses following intratracheal instillation of fine and ultrafine carbon black in rats, Inhal. Toxicol, 11, 709, 1996a.
109. Li, Y. et al., ESR evidence for the generation of reactive oxygen species from the copper-mediated oxidation of the benzene metabolite, hydroquinone: role in DNA damage, Chem. Biol. Interact., 94, 101, 1995.
110. Lin, X., Zhuang, Z., and Costa, M., Analysis of residual amino acid-DNA crosslinks induced in intact cells by nickel and chromium compounds, Carcinogenesis, 13, 1763, 1992.
111. Linden, M. et al., Glutathione in bronchoalveolar lavage fluid from smokers is related to humoral markers of inflammatory cell activity, Inflammation, 13, 651-658, 1989.
112. Lynn, S. et al., Reactive oxygen species are involved in nickel inhibition of DNA repair, Environ. Mol. Mutagen., 29, 208, 1997.
113. McCay, P. B., Vitamin E: interactions with free radicals and ascorbate, Ann. Rev. Nutr., 5, 323, 1985.
114. Manoli, E. et al., Profile analysis of ambient and source emitted particle-bound polycyclic aromatic hydrocarbons from three sites in northern Greece, Chemosphere, 56, 867, 2004.
115. Menon, P. et al., Passive cigarette smoke-challenge studies: increase in bronchial hyper-reactivity, J. Allergy Clin. Immunol., 89, 560, 1992.
116. Monn, C. et al., Ambient PM(10) extracts inhibit phagocytosis of defined inert model particles by alveolar macrophages, Inhal. Toxicol., 14, 369, 2002.
117. Mudway, I. S. and Kelly, F. J., Ozone and the lung: a sensitive issue, Mol. Aspects Med., 21, 1, 2000.
118. Mudway, I. S. et al., Antioxidant consumption and repletion kinetics in nasal lavage fluid following exposure of healthy human volunteers to ozone, Eur. Respir. J., 13, 1429, 1999.
119. Mudway, I. S. et al., Differences in basal airway antioxidant concentrations are not predictive of individual responsiveness to ozone: a comparison of healthy and mild asthmatic subjects, Free Radic. Biol. Med., 31, 962, 2001.
120. Mudway, I. S. et al., An in vitro and in vivo investigation of the effects of diesel exhaust on human airway lining fluid antioxidants, Arch. Biochem. Biophys., 423, 200, 2004.
121. Mueller-Anneling, L. et al., Ambient Endotoxin Concentrations in PM10 from Southern California, Environ. Health Perspect., 112, 583, 2004.
122. Nakamura, H. et al., Effect of vitamin E on the response of lung antioxidant enzymes in young rats exposed to hyperoxia, Kobe J. Med. Sci., 33, 53, 1987.
123. Nauss, K., and Diesel Working Group, In Diesel Exhaust: A Critical Analysis of Emissions, Exposure and Health Effects, 1995.
124. Niki, E., Yamamoto, Y., and Kamiya, Y., Effect of the phytyl tail of vitamin E on its antioxidant activity, Life Chem. Reps., 3, 35, 1985.
125. Niki, E., Takahashi, M., and Komuro, E., Antioxidant activity of vitamin E in liposomal membranes, Chem. Let., 1573, 1986.
126. Nordenhall, C. et al., Airway inflammation following exposure to diesel exhaust: a study of time kinetics using induced sputum, Eur. Respir. J., 15, 1046, 2000.
127. Nualart, F. J. et al., Recycling of vitamin C by a bystander effect, J. Biol. Chem., 278, 10128, 2003.
128. Oberdörster, G., Ferin, J., and Lehnert, B. E., Correlation between particle size, in vivo particle persistence, and lung injury, Environ. Health Perspect., 102, 173, 1994.
129. Oberdörster, G., Oberdörster, E., and Oberdörster, J., Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles, Environ. Health Perspect., 113, 823, 2005.
130. Oberdörster, G. et al., Thermal degradation events as health hazards: particle vs gas phase effects, mechanistic studies with particles, Acta Astronaut., 27, 251, 1992.
131. Ollier, W. E. R. et al., Association of homozygosity for glutathione S-transferase: GSTM1 null alleles is associated with the RoC/LaK autoantibody profile in patients with systemic lupus erythematosus, Arthritis Rheum., 39, 1763, 1996.
132. Oury, T. D. et al., Extracellular superoxide dismutase in vessels and airways of humans and baboons, Free Radic. Biol. Med., 20, 957, 1996.
133. Pacht, E. R. and Davis, W. B., Role of transferrin and ceruloplasmin in antioxidant activity of lung epithelial lining fluid, J. Appl. Physiol., 64, 2092, 1988.
134. Packer, J. E., Slater, T. F., and Wilson, R. L., Direct observation of a free radical interaction between vitamin E and vitamin C, Nature, 278, 737, 1979.
135. Park, J. B. and Levine, M., Purification, cloning and expression of dehydroascorbic acid-reducing activity from human neutrophils: identification as glutaredoxin, Biochem. J., 315, 931, 1996.
136. Park, J. H. et al., House dust endotoxin and wheeze in the first year of life, Am. J. Respir. Crit. Care Med., 163, 322, 2001.
137. Peden, D. B. et al., Uric acid is a major antioxidant in human nasal airway secretions, Proc. Natl. Acad. Sci. U.S.A., 87, 7638, 1990.
138. Peden, D. B. et al., Nasal secretion of the ozone scavenger uric acid, Am. Rev. Respir. Dis., 148, 455, 1993.
139. Peto, R. et al., Mortality from tobacco in developed countries: indirect estimation from national vital statistics, Lancet, 339, 1268, 1992.
140. Pope, C. A. et al., Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults, Am. J. Respir. Crit. Care Med., 151, 669, 1995.
141. Pourazar, J. et al., Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways, Am. J. Physiol. Lung Cell. Mol. Physiol, 289, L724, 2005.
142. Quinlan, G. J., Evans, T. W., and Gutteridge, J. M., Iron and the redox status of the lungs, Free Radic. Biol. Med., 33, 1306, 2002.
143. Rahman, I. and MacNee, W., Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease, Thorax, 51, 348, 1996.
144. Rahman, I., Skwarska, E., and MacNee, W., Attenuation of oxidant/antioxidant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease, Thorax, 52, 565, 1997.
145. Rahman, I. et al., Systemic oxidative stress in asthma, COPD, and smokers, Am. J. Respir. Crit. Care Med, 154, 1055, 1996a.
146. Rahman, I. et al., Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cell, FEBS Lett, 396, 21, 1996b.
147. Rahman, I. et al., 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease, Am. J. Respir. Crit. Care Med., 166, 490, 2002.
148. Reif, D. W., Ferritin as a source of iron for oxidative damage, Free Radic. Biol. Med., 12, 417, 1992.
149. Renwick, L. C. et al., Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types, Occup. Environ. Med., 61, 442, 2004.
150. Repine, J. E., Bast, A., and Lankhorst, I., Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group, Am. J. Respir. Crit. Care Med., 156, 341, 1997.
151. Ribarov, S. R., Benov, L. C., and Bechev, I. C., The effect of lead on haemoglobin-catalyzed lipid peroxidation, Biochem. Biophys. Acta., 664, 453, 1981.
152. Rodriguez, R. E. et al., Nickel-induced lipid peroxidation in the liver of different strains of mice and its relation to nickel effects on antioxidant systems, Toxicol. Lett., 57, 269, 1991.
153. Rumsey, S. C. et al., Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid, J. Biol. Chem., 272, 1898, 1997.
154. Rustow, B. et al., Type II pneumocytes secrete vitamin E together with surfactant lipids, Am. J. Physiol, 265, L133, 1993.
155. Sagai, M. et al., Biological effects of diesel exhaust particles. I. In vitro production of superoxide and in vivo toxicity in mouse, Free Radic. Biol. Med., 14, 37, 1993.
156. Salvi, S. et al., Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers, Am. J. Respir. Crit. Care Med., 159, 702, 1999.
157. Samet, J. M., Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994, N. Engl. J. Med., 343, 1742, 2000.
158. Scheepers, P. T. and Bos, R. P., Combustion of diesel fuel from a toxicological perspective. II. Toxicity, Int. Arch. Occup. Environ. Health, 64, 163, 1992.
159. Sherman, C. B. et al., Firefighting acutely increases airway responsiveness, Am. Rev. Respir. Dis., 140, 185, 1989.
160. Shi, X. and Dalal, N. S., Superoxide-independent reduction of vanadate by rat liver microsomes/NAD(P)H: vanadate reductase activity, Arch. Biochem. Biophys., 295, 70, 1992.
161. Shi, X. and Dalal, N. S., Vanadate-mediated hydroxyl radical generation from superoxide radical in the presence of NADH: Haber-Weiss vs Fenton mechanism, Arch. Biochem. Biophys., 307, 336, 1993.
162. Shvedova, A. A. et al., Unusual inflammatory and fibrogenic pulmonary responses to single- walled carbon nanotubes in mice, Am. J. Physiol. Lung Cell. Mol. Physiol., 289 (5), 698, 2005.
163. Sies, H., Oxidative stress. Oxidants and Antioxidants, Academic Press, London, 1991, chap. II, 1.
164. Skoza, L., Snyder, A., and Kikkawa, Y., Ascorbic acid in bronchoalveolar wash, Lung, 161, 99, 1983.
165. Smith, L. J., Anderson, J., and Shamsuddin, M., Gluthathione localization and distribution after intratrachial installation. Implications for treatment, Am. Rev. Respir. Dis., 145, 153, 1992.
166. Squadrito, G. L. et al., Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter, Free Radic. Biol. Med., 31, 1132, 2001.
167. Stenfors, N., Nordenhall, C., Salvi, S. S., Mudway, I., Soderberg, M., Blomberg, A., Helleday, R., Levin, J. O., Holgate, S. T., Kelly, F. J., Frew, A. J., Sandstrom, T., Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel, Eur. Respir. J., 23, 82, 2004.
168. Stinson, T. J. et al., The relationship between nickel chloride-induced peroxidation and DNA strand breakage in rat liver, Toxicol. Appl. Pharmacol., 117, 98, 1992.
169. Stites, S. W. et al., Increased concentrations of iron and isoferritins in the lower respiratory tract of patients with stable cystic fibrosis, Am. J. Respir. Crit. Care Med., 160, 796, 1999.
170. Stohs, S. J. and Bagchi, D., Oxidative mechanisms in the toxicity of metal ions, Free Radic. Biol. Med., 18, 321, 1995.
171. Strange, R. C. and Fryer, A. A., The glutathione S-transferases: influence of polymorphism on susceptibility to nonfamilial cancers, In Metabolic Polymorphisms and Cancer, Boffetta, P., Caporaso, N., Cuzick, J., Lang, M., and Vineis, P., eds., IARC Scientific Publications, Lyon, 231, 1999.
172. Takebe, G. et al., A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P, J. Biol. Chem., 277, 41254, 2002.
173. Tang, L. X., Yang, J. L., and Shen, X., Effects of additional iron-chelators on Fe(2C)-initiated lipid peroxidation: evidence to support the Fe2C.Fe3C complex as the initiator, J. Inorg. Biochem., 68, 265, 1997.
174. Thompson, A. B. et al., Lower respiratory tract lactoferrin and lysozyme arise primarily in the airways and are elevated in association with chronic bronchitis, J. Lab. Clin. Med., 115, 148, 1990.
175. Toth, K. M. et al., Erythrocytes from cigarette smokers contain more glutathione and catalase and protect endothelial cells from hydrogen peroxide better than erythrocytes from nonsmokers, Am. Rev. Respir. Dis., 134, 281, 1986.
176. Tran, C. L. et al., Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance, Inhal. Toxicol., 12, 101, 2000.
177. Turi, J. L. et al., The iron cycle and oxidative stress in the lung, Free Radic. Biol. Med., 36, 850, 2003.
178. Ulfvarson, U. et al., Effects of exposure to vehicle exhaust on health, Scand. J. Work Environ. Health, 13, 505, 1987.
179. Vallyathan, V. et al., Changes in bronchoalveolar lavage indices associated with radiographic classification in coal miners, Am. J. Respir. Crit. Care Med., 162, 958, 2000.
180. van den Dobbelsteen, D. J. et al., Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody, J. Biol. Chem., 271, 15420, 1996.
181. van der Vliet, A. et al., Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids, Am. J. Physiol, 276, L289, 1999.
182. van Strien, R. T. et al., Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health, J. Allergy Clin. Immunol., 113, 860, 2004.
183. van Vliet, P. et al., Motor vehicle exhaust and chronic respiratory symptoms in children living near freeways, Environ. Res., 74, 122, 1997.
184. Verstraeten, S. V. et al., Myelin is the preferential target for Al-mediated oxidative damage, Arch. Biochem. Biophys., 344, 289, 1997.
185. Vistal, J. J., Health effects of diesel exhaust particulate emissions, Bull. NY Acid Med., 56, 914, 1980.
186. Wang, X. and Quinn, P. J., Vitamin E and its function in membranes, Prog. Lipid Res., 38, 309, 1999.
187. Willis, R. J. and Kratzing, C. C., Ascorbate acid in rat lung, Biochem. Biophys. Res. Commun., 59, 1250, 1974.
188. Wilson, M. R. et al., Interactions between ultrafine particles and transition metals in vivo and in vitro, Toxicol. Appl. Pharmacol., 184, 172, 2002.
189. Winkler, B. S., Orselli, S. M., and Rex, T. S., The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective, Free Radic. Biol. Med., 17, 333, 1994.
190. Winterbourn, C. C., Comparative reactivities of various biological compounds with myeloperoxidasehydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite, Biochim. Biophys. Acta., 840, 204, 1985.
191. Winterbourn, C. C., Toxicity of iron and hydrogen peroxide: the Fenton reaction, Toxicol. Lett., 82, 969, 1995.
192. Witting, L. A., Vitamin E and lipid antioxidants in free radical-initiated reactions, In Free Radicals in Biology, Pryor, W. A., ed., Academic Press, New York, p. 259, 1980.
193. Yang, F. et al., Cellular expression of ceruloplasmin in baboon and mouse lung during development and inflammation, Am. J. Respir. Cell Mol. Biol., 14, 161, 1996.
194. Ye, J. et al., Critical role of glass fiber length in TNF_ production and transcription factor activation in macrophages, Am. J. Physiol, 276, L426, 1999.
195. Yiin, S. J. and Lin, T. H., Lead catalyzed peroxidation of essential unsaturated fatty acid, Biol. Trace Elem. Res., 50, 167, 1995.
196. Zago, M. P. and Oteiza, P. I., The antioxidant properties of zinc: interactions with iron and antioxidants, Free Rad. Biol. Med., 31, 266, 2001.
197. Zatta, P. et al., Aluminium (III) as a promoter of cellular oxidation, Coord. Chem. Rev., 228, 271, 2002.
198. Zhang, Q. et al., Comparative toxicity of standard nickel and ultrafine nickel in lung after intratracheal instillation, J. Occup. Health, 45, 23, 2003.
199. Zhuang, Z., Huang, X., and Costa, M., Protein oxidation and amino acid-DNA crosslinking by nickel compounds in intact cultured cells, Toxicol. Appl. Pharmacol., 126, 319, 1994.
200. Zielinski, H. et al., Modeling the interactions of particulates with epithelial lining fluid antioxidants, Am. J. Physiol, 277, L719, 1999.