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Volumn 107, Issue SUPPL. 1, 1999, Pages 37-47

Polymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancer

Author keywords

CYP1A1; CYP2D6; CYP2E1; Genetic polymorphisms; GSTM1; GSTM3; GSTP1; GSTT1; NAT1; NAT2

Indexed keywords

ACYLTRANSFERASE; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; OXIDOREDUCTASE; XENOBIOTIC AGENT;

EID: 0032933160     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.99107s137     Document Type: Review
Times cited : (102)

References (212)
  • 1
    • 0027401607 scopus 로고
    • The multistep nature of cancer
    • Vogelstein B, Kinzler KW. The multistep nature of cancer. Trends Genet 9:138-141 (1993).
    • (1993) Trends Genet , vol.9 , pp. 138-141
    • Vogelstein, B.1    Kinzler, K.W.2
  • 3
    • 0026457950 scopus 로고
    • Multistep carcinogenesis: A 1992 perspective
    • Sugimura T. Multistep carcinogenesis: a 1992 perspective. Science 258:603-607 (1992).
    • (1992) Science , vol.258 , pp. 603-607
    • Sugimura, T.1
  • 4
    • 0030025772 scopus 로고    scopus 로고
    • Vogelstein b. Life (and death) in a malignant tumour
    • Kinzler KW, Vogelstein B. Life (and death) in a malignant tumour. Nature 379:19-20 (1996).
    • (1996) Nature , vol.379 , pp. 19-20
    • Kinzler, K.W.1
  • 6
    • 13844323012 scopus 로고
    • The genetic toxicology of putative nongenotoxic carcinogens
    • Jackson MA, Stack HF, Waters MD. The genetic toxicology of putative nongenotoxic carcinogens. Mutat Res 296:241-277 (1993).
    • (1993) Mutat Res , vol.296 , pp. 241-277
    • Jackson, M.A.1    Stack, H.F.2    Waters, M.D.3
  • 7
    • 0029564557 scopus 로고
    • Mechanisms for species differences in receptor-mediated carcinogenesis
    • Barret JC. Mechanisms for species differences in receptor-mediated carcinogenesis. Mutat Res 333:189-202 (1995).
    • (1995) Mutat Res , vol.333 , pp. 189-202
    • Barret, J.C.1
  • 8
    • 0028936492 scopus 로고
    • Model for the epigenetic mechanism of action of nongenotoxic carcinogens
    • Costa M. Model for the epigenetic mechanism of action of nongenotoxic carcinogens. Am J Clin Nutr 61:666S-669S (1995).
    • (1995) Am J Clin Nutr , vol.61
    • Costa, M.1
  • 9
    • 0028961525 scopus 로고
    • Genetic polymorphism and cancer susceptibility: Fourteenth sapporo cancer seminar
    • Gonzalez FJ. Genetic Polymorphism and Cancer Susceptibility: Fourteenth Sapporo Cancer Seminar. Cancer Res 55:710-715 (1995).
    • (1995) Cancer Res , vol.55 , pp. 710-715
    • Gonzalez, F.J.1
  • 10
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • Nebert DW, McKinnon RA, Puga A. Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol 15:273-280 (1996).
    • (1996) DNA Cell Biol , vol.15 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 11
    • 0027517396 scopus 로고
    • Pharmacogenetics: Its biologic roots and the medical challenge
    • Kalow W. Pharmacogenetics: its biologic roots and the medical challenge. Clin Pharmacol Ther 54:235-241 (1993).
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 235-241
    • Kalow, W.1
  • 12
    • 0028568658 scopus 로고
    • Genotyping for polymorphisms in xenobiotic metabolism as predictor of disease susceptibility
    • Daly AK, Cholerton S, Armstrong M, Idle JR. Genotyping for polymorphisms in xenobiotic metabolism as predictor of disease susceptibility. Environ Health Perspect 102:S44-S61 (1994).
    • (1994) Environ Health Perspect , vol.102
    • Daly, A.K.1    Cholerton, S.2    Armstrong, M.3    Idle, J.R.4
  • 13
    • 0027954308 scopus 로고
    • Catalytic selectivity of human cytochrome P450 enzymes: Relevance to drug metabolism and toxicity
    • Guengerich FP. Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity. Toxicol Lett 70:133-138 (1994).
    • (1994) Toxicol Lett , vol.70 , pp. 133-138
    • Guengerich, F.P.1
  • 14
    • 0025061180 scopus 로고
    • Activation of promutagens by human cDNA expressed cytochrome P450s
    • Gonzalez FJ, Aoyama T, Gelboin HV. Activation of promutagens by human cDNA expressed cytochrome P450s. Prog Clin Biol Res 340B:77-86 (1990).
    • (1990) Prog Clin Biol Res , vol.340 B , pp. 77-86
    • Gonzalez, F.J.1    Aoyama, T.2    Gelboin, H.V.3
  • 15
    • 0028820801 scopus 로고
    • Role of cytochrome P4501A2 in chemical carcinogenesis: Implications for human variability in expression and enzyme activity
    • Eaton DL, Gallagher EP, Bammler TK, Kunze KL. Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity. Pharmacogenetics 5:259-274 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 259-274
    • Eaton, D.L.1    Gallagher, E.P.2    Bammler, T.K.3    Kunze, K.L.4
  • 16
    • 0026035519 scopus 로고
    • Role of human cytochrome P450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich, FP, Kim DH, Iwasaki M. Role of human cytochrome P450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168-179 (1991).
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Kim, D.H.1    Iwasaki, M.2
  • 17
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 caucasians
    • Shimada T, Yamasaki H, Mimura M, Inui Y, Guengerich FP. Interindividual variations in human liver cytochrome P450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-423 (1994).
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamasaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 18
    • 0027458138 scopus 로고
    • The ah-receptor: Genetics, structure and function
    • Swanson HI, Bradfield CA. The AH-receptor: genetics, structure and function. Pharmacogenetics 3:213-230 (1993).
    • (1993) Pharmacogenetics , vol.3 , pp. 213-230
    • Swanson, H.I.1    Bradfield, C.A.2
  • 23
    • 0025950370 scopus 로고
    • Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a european population
    • Broly F, Gaedigk A, Heim M, Eichelbaum M, Morike K, Meyer UA. Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol 10:545-558 (1991).
    • (1991) DNa Cell Biol , vol.10 , pp. 545-558
    • Broly, F.1    Gaedigk, A.2    Heim, M.3    Eichelbaum, M.4    Morike, K.5    Meyer, U.A.6
  • 24
    • 0026240125 scopus 로고
    • Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes
    • Daly AK, Armstrong M, Monkman SC, Idle ME, Idle JR. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes. Pharmacogenetics 1:33-41 (1991).
    • (1991) Pharmacogenetics , vol.1 , pp. 33-41
    • Daly, A.K.1    Armstrong, M.2    Monkman, S.C.3    Idle, M.E.4    Idle, J.R.5
  • 25
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl MI, Sjöqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci USA 90:11825-11829 (1993).
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.I.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 26
    • 0028208792 scopus 로고
    • Pharmacogenetics: The slow, the rapid, and the ultrarapid
    • Meyer UA. Pharmacogenetics: the slow, the rapid, and the ultrarapid. Proc Natl Acad Sci USA 91:1983-1984 (1994).
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1983-1984
    • Meyer, U.A.1
  • 27
    • 0029064096 scopus 로고
    • Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis
    • Dahl M-L, Johansson I, Bertilsson L, Ingelman-Sundberg M, Sjöqvist F. Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis. J Pharmacol Exp Ther 274:516-520 (1995).
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 516-520
    • Dahl, M.-L.1    Johansson, I.2    Bertilsson, L.3    Ingelman-Sundberg, M.4    Sjöqvist, F.5
  • 28
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmöller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 60:284-295 (1997).
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmöller, J.2    Bauer, S.3    Roots, I.4
  • 29
    • 0027965620 scopus 로고
    • Genetic analysis of the chinese cytochrome P450D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
    • Johansson I, Oscarson M, Vue Q-Y, Bertilsson L, Sjöqvist F, Ingelman-Sundberg M. Genetic analysis of the Chinese cytochrome P450D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol Pharmacol 46:452-459 (1994).
    • (1994) Mol Pharmacol , vol.46 , pp. 452-459
    • Johansson, I.1    Oscarson, M.2    Vue, Q.-Y.3    Bertilsson, L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 31
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in white population
    • Agundéz JAG, Ledesma MC, Ladero JM, Benítez J. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in white population. Clin Pharmacol Ther 57:265-269 (1995).
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agundéz, J.A.G.1    Ledesma, M.C.2    Ladero, J.M.3    Benítez, J.4
  • 33
    • 0030432585 scopus 로고    scopus 로고
    • Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
    • Aklillu E, Persson I, Bertilsson L, Johansson I, Rodrigues F, Ingelman-Sundberg M. Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J Pharmacol Exp Ther 278:441-446 (1996).
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 441-446
    • Aklillu, E.1    Persson, I.2    Bertilsson, L.3    Johansson, I.4    Rodrigues, F.5    Ingelman-Sundberg, M.6
  • 35
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • Nebert DW, Mckinnon RA, Puga A. Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol 15:273-280 (1996).
    • (1996) DNA cell biol , vol.15 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 36
    • 0031799305 scopus 로고    scopus 로고
    • Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and parkinson's disease
    • Rostami-Hodjegan A, Lenard MS, Woods HE, Tucker GT. Meta-Analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease. Pharmacogenetics 8:227-238 (1998).
    • (1998) Pharmacogenetics , vol.8 , pp. 227-238
    • Rostami-Hodjegan, A.1    Lenard, M.S.2    Woods, H.E.3    Tucker, G.T.4
  • 37
    • 0030047286 scopus 로고    scopus 로고
    • The effect of tobacco on lung cancer risk depends on CYP2D6 activity
    • Bouchardy C, Benhamou S, Dayer P. The effect of tobacco on lung cancer risk depends on CYP2D6 activity. Cancer Res 56:251-253 (1996).
    • (1996) Cancer Res , vol.56 , pp. 251-253
    • Bouchardy, C.1    Benhamou, S.2    Dayer, P.3
  • 38
    • 0026631268 scopus 로고
    • Stereoselective metabolism of (-)-benzo [a]pyrene-7,8-diol by human lung microsomes and peripheral blood lymphocytes: Effects of smoking
    • Rojas M, Camus AM, Alexandrov K, Husgafvel-Pursiainen K, Anttila S, Vainio H, Bartsch H. Stereoselective metabolism of (-)-benzo [a]pyrene-7,8-diol by human lung microsomes and peripheral blood lymphocytes: effects of smoking. Carcinogenesis 13:929-933 (1992).
    • (1992) Carcinogenesis , vol.13 , pp. 929-933
    • Rojas, M.1    Camus, A.M.2    Alexandrov, K.3    Husgafvel-Pursiainen, K.4    Anttila, S.5    Vainio, H.6    Bartsch, H.7
  • 39
    • 0029850968 scopus 로고    scopus 로고
    • Metabolic activation of the potent carcinogen dibenzo[a]pyrene by human recombinant cytochromes P450, lung and liver microsomes
    • Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Metabolic activation of the potent carcinogen dibenzo[a]pyrene by human recombinant cytochromes P450, lung and liver microsomes. Carcinogenesis 17:2429-2433 (1996).
    • (1996) Carcinogenesis , vol.17 , pp. 2429-2433
    • Shou, M.1    Krausz, K.W.2    Gonzalez, F.J.3    Gelboin, H.V.4
  • 41
    • 0015682899 scopus 로고
    • Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma
    • Kellermann G, Shaw CR, Luyten-Kellerman M. Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma. N Engl J Med 289:934-937 (1973).
    • (1973) N Engl J Med , vol.289 , pp. 934-937
    • Kellermann, G.1    Shaw, C.R.2    Luyten-Kellerman, M.3
  • 42
    • 0025236927 scopus 로고
    • Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P4501A1 gene
    • Kawajiri K, Nakachi K, Imai K, Yoshii A, Shinoda N, Watanabe J. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P4501A1 gene. FEBS Lett 263:131-133 (1990).
    • (1990) FEBS Lett , vol.263 , pp. 131-133
    • Kawajiri, K.1    Nakachi, K.2    Imai, K.3    Yoshii, A.4    Shinoda, N.5    Watanabe, J.6
  • 43
    • 0025914145 scopus 로고
    • Genetic linkage of lung cancer-associated Mspl polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene
    • Hayashi SI, Watanabe J, Nakachi K, Kawajiri K. Genetic linkage of lung cancer-associated Mspl polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene. J Biochem 110: 407-411 (1991).
    • (1991) J Biochem , vol.110 , pp. 407-411
    • Hayashi, S.I.1    Watanabe, J.2    Nakachi, K.3    Kawajiri, K.4
  • 44
    • 0029854529 scopus 로고    scopus 로고
    • A C4887A polymorphism in exon 7 of human CYP1A1: Population frequency, mutation linkages, and impact on lung cancer susceptibility
    • Cascorbi I, Brockmöller J, Roots I. A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res 56:4965-4969 (1996).
    • (1996) Cancer Res , vol.56 , pp. 4965-4969
    • Cascorbi, I.1    Brockmöller, J.2    Roots, I.3
  • 47
    • 0031550543 scopus 로고    scopus 로고
    • In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility
    • Persson I, Johansson I, Ingelman-Sundberg M. In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility. Biochem Biophys Res Commun 231:227-230 (1997).
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 227-230
    • Persson, I.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 48
    • 0024829409 scopus 로고
    • The ah locus: Genetic differences in toxicity, cancer, mutation and birth defects
    • Nebert DW. The Ah locus: genetic differences in toxicity, cancer, mutation and birth defects. CRC Crit Rev Toxicol 20:153-174 (1989).
    • (1989) CRC Crit Rev Toxicol , vol.20 , pp. 153-174
    • Nebert, D.W.1
  • 49
    • 0027458138 scopus 로고
    • The AH-receptor: Genetics, structure and function
    • Swanson HI, Bradfield CA. The AH-receptor: genetics, structure and function. Pharmacogenetics 3:213-230 (1993).
    • (1993) Pharmacogenetics , vol.3 , pp. 213-230
    • Swanson, H.I.1    Bradfield, C.A.2
  • 50
    • 0001360416 scopus 로고    scopus 로고
    • Genetic polymorphisms and the risk of cancer: A review of the literature
    • d'Errico A, Taioli E, Chen X, Vineis P. Genetic polymorphisms and the risk of cancer: a review of the literature. Biomarkers 1:149-173 (1996).
    • (1996) Biomarkers , vol.1 , pp. 149-173
    • D'Errico, A.1    Taioli, E.2    Chen, X.3    Vineis, P.4
  • 55
    • 0026921501 scopus 로고
    • Point mutational Mspl and lle/Val polymorphism linked in the CYP1A1 gene: Lack of association with susceptibility to lung cancer in a finnish population
    • Hirvonen A, Husgafvel-Pursianen K, Karjalainen A, Anttila S, Vainio H. Point mutational Mspl and lle/Val polymorphism linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish population. Cancer Epidemiol Biomarkers Prev 1:485-489 (1992).
    • (1992) Cancer Epidemiol Biomarkers Prev , vol.1 , pp. 485-489
    • Hirvonen, A.1    Husgafvel-Pursianen, K.2    Karjalainen, A.3    Anttila, S.4    Vainio, H.5
  • 57
    • 0028168178 scopus 로고
    • Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1 a study on host factors in relation to age at onset, gender and histological cancer types
    • Alexandrie A-K, Ingelman-Sundberg M, Seidegård J, Tomling G, Rannug A. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1 a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis 15:1785-1790 (1994).
    • (1994) Carcinogenesis , vol.15 , pp. 1785-1790
    • Alexandrie, A.-K.1    Ingelman-Sundberg, M.2    Seidegård, J.3    Tomling, G.4    Rannug, A.5
  • 60
    • 0031431662 scopus 로고    scopus 로고
    • Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetra-hydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility
    • Esteller M, Garcia A, Martinez-Palones JM, Xercavins J, Reventes J. Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetra-hydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility. Carcinogenesis 18:2307-2311 (1997).
    • (1997) Carcinogenesis , vol.18 , pp. 2307-2311
    • Esteller, M.1    Garcia, A.2    Martinez-Palones, J.M.3    Xercavins, J.4    Reventes, J.5
  • 61
    • 0028820801 scopus 로고
    • Role of cytochrome P4501A2 in chemical carcinogenesis: Implications for human variability in expression and enzyme activity
    • Eaton DA, Gallagher EP, Bammler TK, Kunze KL. Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity. Pharmacogenetics 5:259-274 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 259-274
    • Eaton, D.A.1    Gallagher, E.P.2    Bammler, T.K.3    Kunze, K.L.4
  • 62
    • 0024445437 scopus 로고
    • Human CYP1A2 sequence, gene structure, comparison with the mouse and rat orthologous gene, and genetic differences in liver IA2 mRNA concentrations
    • Ikeya K, Jaiswal AK, Owens RA, Jones JE, Nebert DW, Kimura S. Human CYP1A2 sequence, gene structure, comparison with the mouse and rat orthologous gene, and genetic differences in liver IA2 mRNA concentrations. Mol Endocrinol 3:1399-1408 (1989).
    • (1989) Mol Endocrinol , vol.3 , pp. 1399-1408
    • Ikeya, K.1    Jaiswal, A.K.2    Owens, R.A.3    Jones, J.E.4    Nebert, D.W.5    Kimura, S.6
  • 64
    • 0027515143 scopus 로고
    • Acetylation phenotype and cytochrome P4501A2 phenotype are unlikely to be associated with peripheral arterial disease
    • llett KF, Castleden WM, Vandongen YK, Stacey MC, Butler MA, Kadlubar FF. Acetylation phenotype and cytochrome P4501A2 phenotype are unlikely to be associated with peripheral arterial disease. Clin Pharmacol Ther 54:317-322 (1993).
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 317-322
    • Castleden, W.M.1    Vandongen, Y.K.2    Stacey, M.C.3    Butler, Ma.4    Kadlubar, F.F.5
  • 65
    • 0029048772 scopus 로고
    • The CYP2A gene subfamily: Species differences, regulation, catalytic activities and role in chemical carcinogenesis
    • Fernandez-Salguero P, Gonzalez FJ. The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis. Pharmacogenetics 5:S123-S128 (1995).
    • (1995) Pharmacogenetics , vol.5
    • Fernandez-Salguero, P.1    Gonzalez, F.J.2
  • 67
    • 0026582870 scopus 로고
    • Comparison of a novel thin layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydrocoumarin in human urine
    • Cholerton S, Idle ME, Vas A, Gonzalez FJ, Idle JR. Comparison of a novel thin layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydrocoumarin in human urine. J Chromatogr 575:325-330 (1992).
    • (1992) J Chromatogr , vol.575 , pp. 325-330
    • Cholerton, S.1    Idle, M.E.2    Vas, A.3    Gonzalez, F.J.4    Idle, J.R.5
  • 68
    • 0026934672 scopus 로고
    • Interindividual variability of coumarin 7-hydroxylation in healthy volunteers
    • Rautio A, Kraul H, Kojo A, Salmela E, Pelkonen O. Interindividual variability of coumarin 7-hydroxylation in healthy volunteers. Pharmacogenetics 2:227-233 (1992).
    • (1992) Pharmacogenetics , vol.2 , pp. 227-233
    • Rautio, A.1    Kraul, H.2    Kojo, A.3    Salmela, E.4    Pelkonen, O.5
  • 69
    • 7144257874 scopus 로고    scopus 로고
    • A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)
    • Nunoya K, Yokoi T, Kimura K, Inoue K, Kodama T, Funayama M, Nagashima K, Funae Y, Green C, Kinoshita M, et al. A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502). Pharmacogenetics 8:239-249 (1998).
    • (1998) Pharmacogenetics , vol.8 , pp. 239-249
    • Nunoya, K.1    Yokoi, T.2    Kimura, K.3    Inoue, K.4    Kodama, T.5    Funayama, M.6    Nagashima, K.7    Funae, Y.8    Green, C.9    Kinoshita, M.10
  • 70
    • 0032565878 scopus 로고    scopus 로고
    • Nicotine metabolism defect reduces smoking [letter to the editor]
    • Pianezza ML, Sellers EM, Tyndale RF. Nicotine metabolism defect reduces smoking [Letter to the Editor]. Nature 393:750 (1998).
    • (1998) Nature , vol.393 , pp. 750
    • Pianezza, M.L.1    Sellers, E.M.2    Tyndale, R.F.3
  • 72
    • 0030773244 scopus 로고    scopus 로고
    • Lung cancer risk in relation to the CYP2C9 genetic polymorphism among caucasians in Los Angeles county
    • London SJ, Sullivan-Klose T, Daly AK, Idle JR. Lung cancer risk in relation to the CYP2C9 genetic polymorphism among Caucasians in Los Angeles County. Pharmacogenetics 7:401-404 (1997).
    • (1997) Pharmacogenetics , vol.7 , pp. 401-404
    • London, S.J.1    Sullivan-Klose, T.2    Daly, A.K.3    Idle, J.R.4
  • 74
    • 0030904031 scopus 로고    scopus 로고
    • Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various oriental, caucasian, Saudi Arabian and American black populations
    • Goldstein JA, Ishizaki T, Chiba K, De Morais SM, Bell D, Krahn PM, Evans DA. Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations. Pharmacogenetics 7:59-64 (1997).
    • (1997) Pharmacogenetics , vol.7 , pp. 59-64
    • Goldstein, J.A.1    Ishizaki, T.2    Chiba, K.3    De Morais, S.M.4    Bell, D.5    Krahn, P.M.6    Evans, D.A.7
  • 75
    • 18344405507 scopus 로고
    • A taql polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E)
    • McBride OW, Umeno M, Gelboin HV, Gonzalez FJ. A Taql polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E). Nucl Acid Res 15:10071 (1987).
    • (1987) Nucl Acid Res , vol.15 , pp. 10071
    • McBride, O.W.1    Umeno, M.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 77
    • 0026069613 scopus 로고
    • Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer
    • Uematsu F, Kikuchi H, Motomiya M, Abe T, Sagami I, Ohmachi T, Wakui A, Kanamaru R, Watanabe M. Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer. Jpn J Cancer Res 82:254-256 (1991).
    • (1991) Jpn J Cancer Res , vol.82 , pp. 254-256
    • Uematsu, F.1    Kikuchi, H.2    Motomiya, M.3    Abe, T.4    Sagami, I.5    Ohmachi, T.6    Wakui, A.7    Kanamaru, R.8    Watanabe, M.9
  • 79
    • 0026062622 scopus 로고
    • Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene
    • Hayashi S, Watanabe J, Kawajiri K. Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. J Biochem (Tokyo) 110:559-565 (1991).
    • (1991) J Biochem (Tokyo) , vol.110 , pp. 559-565
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 80
    • 0028145234 scopus 로고
    • Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphisms in the 5′-flanking region
    • Watanabe J, Hayashi S, Kawajiri K. Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphisms in the 5′-flanking region. J Biochem (Tokyo) 116:321-326 (1994).
    • (1994) J Biochem (Tokyo) , vol.116 , pp. 321-326
    • Watanabe, J.1    Hayashi, S.2    Kawajiri, K.3
  • 84
    • 0028355767 scopus 로고
    • Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazona: A putative measure of CYP2E1 activity
    • Kim RB, O'Shea D, Wilkinson GR. Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazona: a putative measure of CYP2E1 activity. Pharmacogenetics 4:162-165 (1994).
    • (1994) Pharmacogenetics , vol.4 , pp. 162-165
    • Kim, R.B.1    O'Shea, D.2    Wilkinson, G.R.3
  • 85
    • 0028037221 scopus 로고
    • Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: A putative probe of CYP2E1 activity
    • O'Shea D, Davis SN, Kim RB. Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity. Clin Pharmacol Ther 56:359-367 (1994).
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 359-367
    • O'Shea, D.1    Davis, S.N.2    Kim, R.B.3
  • 86
    • 0029035739 scopus 로고
    • Interindividual variability of 6-hydroxylation of chlorzoxazone in men and women and its relationship to CYP2E1 genetic polymorphisms
    • Kim RB, O'Shea D. Interindividual variability of 6-hydroxylation of chlorzoxazone in men and women and its relationship to CYP2E1 genetic polymorphisms. Clin Pharmacol Ther 57:645-655 (1995).
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 645-655
    • Kim, R.B.1    O'Shea, D.2
  • 87
    • 0028876741 scopus 로고
    • Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe
    • Vessel ES, Seaton TD, A-Rahim YI. Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe. Pharmacogenetics 5:53-57 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 53-57
    • Vessel, E.S.1    Seaton, T.D.2    A-Rahim, Y.I.3
  • 89
    • 0028228772 scopus 로고
    • Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: Possible relevance to low smoking exposure
    • Uematsu F, Ikawa S, Sagami I, Kanamaru R, Abe T, Satoh K, Motomiya M, Watanabe M. Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure. Pharmacogenetics 4:58-63 (1994).
    • (1994) Pharmacogenetics , vol.4 , pp. 58-63
    • Uematsu, F.1    Ikawa, S.2    Sagami, I.3    Kanamaru, R.4    Abe, T.5    Satoh, K.6    Motomiya, M.7    Watanabe, M.8
  • 90
    • 0027302424 scopus 로고
    • The human CYP2E1 gene and lung cancer: Oral and Rsal restriction fragment lenght polymorphisms in a finnish study population
    • Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Karjalainen A, Vainio H. The human CYP2E1 gene and lung cancer: Oral and Rsal restriction fragment lenght polymorphisms in a Finnish study population. Carcinogenesis 14:85-88 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 85-88
    • Hirvonen, A.1    Husgafvel-Pursiainen, K.2    Anttila, S.3    Karjalainen, A.4    Vainio, H.5
  • 91
    • 0031550543 scopus 로고    scopus 로고
    • In vitro kinetics of two human CYPIA1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility
    • Persson I, Johansson I, Ingelman-Sundberg M. In vitro kinetics of two human CYPIA1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility. Biochem Biophys Res Commun 231:227-230 (1997).
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 227-230
    • Persson, I.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 93
    • 0015849224 scopus 로고
    • Mammalian epoxide hydrolases: Inducible enzymes catalyzing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds
    • Oesch F. Mammalian epoxide hydrolases: inducible enzymes catalyzing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds. Xenobiotica 3:305-340 (1973).
    • (1973) Xenobiotica , vol.3 , pp. 305-340
    • Oesch, F.1
  • 94
    • 0016328890 scopus 로고
    • Metabolic activation of benzo(a)pyrene proceeds by a diol epoxide
    • Sims P, Grover PL, Swaisland A, Pal K, Hewer A. Metabolic activation of benzo(a)pyrene proceeds by a diol epoxide. Nature 252:326-328 (1974).
    • (1974) Nature , vol.252 , pp. 326-328
    • Sims, P.1    Grover, P.L.2    Swaisland, A.3    Pal, K.4    Hewer, A.5
  • 95
    • 0017595913 scopus 로고
    • The apparent ubiquity of epoxide hydrolase in rat organs
    • Oesch F, Glatt H, Schimassmann H. The apparent ubiquity of epoxide hydrolase in rat organs. Biochem Pharmacol 26:603-607 (1977).
    • (1977) Biochem Pharmacol , vol.26 , pp. 603-607
    • Oesch, F.1    Glatt, H.2    Schimassmann, H.3
  • 96
    • 0342327333 scopus 로고    scopus 로고
    • The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics
    • Seidegård J, Ekström G. The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. Environ Health Perspect 105:791-799 (1997)
    • (1997) Environ Health Perspect , vol.105 , pp. 791-799
    • Seidegård, J.1    Ekström, G.2
  • 97
    • 0027190318 scopus 로고
    • Human peripheral lymphocytes as indicators of microsomal epoxide hydrolase activity in liver and lung
    • Omiecinski CJ, Aicher L, Holubkov R, Checkoway H. Human peripheral lymphocytes as indicators of microsomal epoxide hydrolase activity in liver and lung. Pharmacogenetics 3:150-158 (1993).
    • (1993) Pharmacogenetics , vol.3 , pp. 150-158
    • Omiecinski, C.J.1    Aicher, L.2    Holubkov, R.3    Checkoway, H.4
  • 99
    • 0027935768 scopus 로고
    • The human microsomal epoxide hydrolase gene (EPHX1): Complete nucleotide sequence and structural characterization
    • Hasset C, Robinson KB, Beck NB, Omiecinski CJ. The human microsomal epoxide hydrolase gene (EPHX1): complete nucleotide sequence and structural characterization. Genomics 23:433-442 (1994).
    • (1994) Genomics , vol.23 , pp. 433-442
    • Hasset, C.1    Robinson, K.B.2    Beck, N.B.3    Omiecinski, C.J.4
  • 100
    • 0028295652 scopus 로고
    • Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants
    • Hasset C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 3:421-128 (1994).
    • (1994) Hum Mol Genet , vol.3 , pp. 421-1128
    • Hasset, C.1    Aicher, L.2    Sidhu, J.S.3    Omiecinski, C.J.4
  • 101
    • 0031927837 scopus 로고    scopus 로고
    • Human microsomal epoxide hydrolase: 5′-flanking region genetic polymorphism
    • Raaka S, Hasset C, Omiecinski CJ. Human microsomal epoxide hydrolase: 5′-flanking region genetic polymorphism. Carcinogenesis 19:387-393 (1998)
    • (1998) Carcinogenesis , vol.19 , pp. 387-393
    • Raaka, S.1    Hasset, C.2    Omiecinski, C.J.3
  • 104
    • 0030849415 scopus 로고    scopus 로고
    • Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema
    • Smith CAD, Harrison DJ. Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema. Lancet 350:630-633 (1997).
    • (1997) Lancet , vol.350 , pp. 630-633
    • Smith, C.A.D.1    Harrison, D.J.2
  • 105
    • 0029561598 scopus 로고
    • The glutathione s-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30:445-600 (1995).
    • (1995) Crit Rev Biochem Mol Biol , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 106
    • 0025228968 scopus 로고
    • The role of glutathione and glutathione transferases in chemical carcinogenesis
    • Coles B, Ketterer B. The role of glutathione and glutathione transferases in chemical carcinogenesis. Crit Rev Biochem Mol Biol 25:47-70 (1990).
    • (1990) Crit Rev Biochem Mol Biol , vol.25 , pp. 47-70
    • Coles, B.1    Ketterer, B.2
  • 107
    • 0010325553 scopus 로고
    • Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion
    • Seidegård J, Vorachek WR, Pero RW, Pearson WR. Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci USA 85:7293-7297 (1988).
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7293-7297
    • Seidegård, J.1    Vorachek, W.R.2    Pero, R.W.3    Pearson, W.R.4
  • 108
    • 0030858074 scopus 로고    scopus 로고
    • Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility
    • Rebbeck TR. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol Biomarkers Prev 6:733-743 (1997).
    • (1997) Cancer Epidemiol Biomarkers Prev , vol.6 , pp. 733-743
    • Rebbeck, T.R.1
  • 109
    • 0029086208 scopus 로고
    • Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and caucasians in Los Angeles county, California
    • London SJ, Daly AK, Cooper J, Navidi WC, Carpenter CL, Idle JR. Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles county, California. J Natl Cancer Inst 87:1246-1253 (1995).
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1246-1253
    • London, S.J.1    Daly, A.K.2    Cooper, J.3    Navidi, W.C.4    Carpenter, C.L.5    Idle, J.R.6
  • 111
    • 0028071251 scopus 로고
    • Glutathione s-transterase M1 and its variants a and b as host factors of bladder cancer susceptibility: A case-control study
    • Brockmöller J, Kerb R, Orakoulis N, Staffeldt B, Roots I. Glutathione S-transterase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study. Cancel Res 54:4103-4111 (1994).
    • (1994) Cancel Res , vol.54 , pp. 4103-4111
    • Brockmöller, J.1    Kerb, R.2    Orakoulis, N.3    Staffeldt, B.4    Roots, I.5
  • 114
    • 0029156516 scopus 로고
    • Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: Association with GSTM1 polymorphism, smoking, and asbestos exposure
    • Anttila S, Luostarinen L, Hirvonen A, Elovaara E, Karjalainen A, Nurminen T, Hayes JD, Vainio H, Ketterer B. Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: association with GSTM1 polymorphism, smoking, and asbestos exposure. Cancer Res 55:3305-3309 (1995).
    • (1995) Cancer Res , vol.55 , pp. 3305-3309
    • Anttila, S.1    Luostarinen, L.2    Hirvonen, A.3    Elovaara, E.4    Karjalainen, A.5    Nurminen, T.6    Hayes, J.D.7    Vainio, H.8    Ketterer, B.9
  • 115
    • 9244246804 scopus 로고    scopus 로고
    • Polymorphism at the glutathione S-transferase locus GSTM3: Interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma
    • Yengi L, Inskip A, Gilford J, Alldersea J, Bailey L, Smith A, Lear JT, Heagerty AH, Bowers B, Hand P, et al. Polymorphism at the glutathione S-transferase locus GSTM3: interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma. Cancer Res 56:1974-1977 (1996).
    • (1996) Cancer Res , vol.56 , pp. 1974-1977
    • Yengi, L.1    Inskip, A.2    Gilford, J.3    Alldersea, J.4    Bailey, L.5    Smith, A.6    Lear, J.T.7    Heagerty, A.H.8    Bowers, B.9    Hand, P.10
  • 116
    • 0030443106 scopus 로고    scopus 로고
    • Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx
    • Jahnke V, Matthias C, Fryer A, Strange R. Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx. Am J Surg 172:671-673 (1996).
    • (1996) Am J Surg , vol.172 , pp. 671-673
    • Jahnke, V.1    Matthias, C.2    Fryer, A.3    Strange, R.4
  • 117
    • 15444355381 scopus 로고    scopus 로고
    • Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: Studies in upper aerodigestive tract cancers
    • Matthias C, Bockmühl U, Jahnke V, Jones PW, Hayes JD, Alldersea J, Gilford J, Bailey L, Bath J, Wortall SF, et al. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers. Pharmacogenetics 8:91-100 (1998).
    • (1998) Pharmacogenetics , vol.8 , pp. 91-100
    • Matthias, C.1    Bockmühl, U.2    Jahnke, V.3    Jones, P.W.4    Hayes, J.D.5    Alldersea, J.6    Gilford, J.7    Bailey, L.8    Bath, J.9    Wortall, S.F.10
  • 118
    • 0032441665 scopus 로고    scopus 로고
    • Role of glutathione S-transferase GSTM1, GSTM3, GSTP1, and GSTT1 genotypes in modulating susceptibility to smoking related lung cancer
    • in press
    • Jourenkova-Mirnova N, Wikman H, Bouchardy C, Voho A, Dayer P, Benhamou S, Hirvonen A. Role of glutathione S-transferase GSTM1, GSTM3, GSTP1, and GSTT1 genotypes in modulating susceptibility to smoking related lung cancer. Pharmacogenetics (in press).
    • Pharmacogenetics
    • Jourenkova-Mirnova, N.1    Wikman, H.2    Bouchardy, C.3    Voho, A.4    Dayer, P.5    Benhamou, S.6    Hirvonen, A.7
  • 119
    • 0030899372 scopus 로고    scopus 로고
    • Molecular cloning, characterization, and expression in eschericia coli of full-length cDNAs of three human glutathione S-transferase pi gene variants. Evidence for differential catalytic activity of the encoded proteins
    • Ali-Osman F, Akande N, Mao J. Molecular cloning, characterization, and expression in Eschericia coli of full-length cDNAs of three human glutathione S-transferase pi gene variants. Evidence for differential catalytic activity of the encoded proteins. J Biol Chem 272:10004-10012 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 10004-10012
    • Ali-Osman, F.1    Akande, N.2    Mao, J.3
  • 120
    • 0028088048 scopus 로고
    • Naturally occurring human glutathione S-transferase GSTP1.1 isoforms with isoleucine and valine at position 104 differ in enzymatic properties
    • Zimniak P, Nanduri B, Piula S, Bandorowicz-Pikula J, Singhal S, Srivastava SK, Awasthi S, Awasrhi JC. Naturally occurring human glutathione S-transferase GSTP1.1 isoforms with isoleucine and valine at position 104 differ in enzymatic properties. Eur J Biochem 224:893-899 (1994).
    • (1994) Eur J Biochem , vol.224 , pp. 893-899
    • Zimniak, P.1    Nanduri, B.2    Piula, S.3    Pikula, J.4    Singhal, S.5    Srivastava, S.K.6    Awasthi, S.7    Awasrhi, J.C.8
  • 121
    • 0031577161 scopus 로고    scopus 로고
    • Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7,8-dihydroxy-9,10-oxy-1.8.9,10-tetrahydrobenzo(a)pyrene
    • Hu X, O'Donnel R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, et al. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7,8-dihydroxy-9,10-oxy-1.8.9,10-tetrahydrobenzo(a)pyrene. Biochem Biophys Res Commun 235:424-428 (1997).
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 424-428
    • Hu, X.1    O'Donnel, R.2    Srivastava, S.K.3    Xia, H.4    Zimniak, P.5    Nanduri, B.6    Bleicher, R.J.7    Awasthi, S.8    Awasthi, Y.C.9    Ji, X.10
  • 122
    • 0031427094 scopus 로고    scopus 로고
    • Identification of genetic polymorphisms at the glutathione S-transferase pi locus and association with susceptibility to bladder, testicular and prostate cancer
    • Harries LW, Stubbins MJ, Forman D, Howard GCW, Wolf R. Identification of genetic polymorphisms at the glutathione S-transferase pi locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis 18:641-644 (1997).
    • (1997) Carcinogenesis , vol.18 , pp. 641-644
    • Harries, L.W.1    Stubbins, M.J.2    Forman, D.3    Howard, G.C.W.4    Wolf, R.5
  • 126
    • 0031906326 scopus 로고    scopus 로고
    • Polymorphism of the pi class glutathione S-transferase in normal populations and cancer patients
    • Harris MJ, Coggan M, Langton L, Wilson SR, Board PG. Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients. Pharmacogenetics 8:27-31 (1998).
    • (1998) Pharmacogenetics , vol.8 , pp. 27-31
    • Harris, M.J.1    Coggan, M.2    Langton, L.3    Wilson, S.R.4    Board, P.G.5
  • 128
    • 0026576778 scopus 로고
    • Dissociation of a new glutathione s-transferase activity in human erythrocytes
    • Schröder KR, Hallier E, Peter H, Bolt HM. Dissociation of a new glutathione S-transferase activity in human erythrocytes. Biochem Pharmacol 43:1671-1674 (1992).
    • (1992) Biochem Pharmacol , vol.43 , pp. 1671-1674
    • Schröder, K.R.1    Hallier, E.2    Peter, H.3    Bolt, H.M.4
  • 129
    • 0028990060 scopus 로고
    • Role of GSTM1 and GSTT1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes
    • Norppa H, Hirvonen A, Järventaus H, Uusküla M, Tasa M, Ojajärvi A, Sorsa M. Role of GSTM1 and GSTT1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes. Carcinogenesis 16:1261-1264 (1995).
    • (1995) Carcinogenesis , vol.16 , pp. 1261-1264
    • Norppa, H.1    Hirvonen, A.2    Järventaus, H.3    Uusküla, M.4    Tasa, M.5    Ojajärvi, A.6    Sorsa, M.7
  • 130
    • 0028918081 scopus 로고
    • Gene deletion of glutathione transferase theta. 1: Correlation with induced genetic damage and potential role in endogeneous mutagenesis
    • Wiencke JK, Pemble S, Ketterer B, Kelsey KT. Gene deletion of glutathione transferase theta. 1: correlation with induced genetic damage and potential role in endogeneous mutagenesis. Cancer Epidemiol Biomarkers Prev 4:253-260 (1995).
    • (1995) Cancer Epidemiol Biomarkers Prev , vol.4 , pp. 253-260
    • Wiencke, J.K.1    Pemble, S.2    Ketterer, B.3    Kelsey, K.T.4
  • 133
    • 15844428130 scopus 로고    scopus 로고
    • Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: Studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers
    • Deakin M, Elder J, Hendrickse C, Peckham D, Baldwin D, Pantin C, Wild N, Leopard P, Bell DA, Jones P, et al. Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers. Carcinogenesis 17:881-884 (1996).
    • (1996) Carcinogenesis , vol.17 , pp. 881-884
    • Deakin, M.1    Elder, J.2    Hendrickse, C.3    Peckham, D.4    Baldwin, D.5    Pantin, C.6    Wild, N.7    Leopard, P.8    Bell, D.A.9    Jones, P.10
  • 135
    • 0030855752 scopus 로고    scopus 로고
    • Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations
    • Kelsey K, Spitz MR, Zuo ZF, Wiencke JK. Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations. Cancer Causes Control 8:554-559 (1997).
    • (1997) Cancer Causes Control , vol.8 , pp. 554-559
    • Kelsey, K.1    Spitz, M.R.2    Zuo, Z.F.3    Wiencke, J.K.4
  • 136
    • 0030875335 scopus 로고    scopus 로고
    • Combinations of susceptible genotypes and individual responses to toxicants
    • Hirvonen A. Combinations of susceptible genotypes and individual responses to toxicants. Environ Health Perspect 105:755-758 (1997).
    • (1997) Environ Health Perspect , vol.105 , pp. 755-758
    • Hirvonen, A.1
  • 137
    • 0002202499 scopus 로고
    • N-acetyltransferase
    • Kalow W, ed. New York:Pergamon Press
    • Evans, DA. N-Acetyltransferase. In: Pharmacogenetics of Drug Metabolism (Kalow W, ed). New York:Pergamon Press, 1992;95-178.
    • (1992) Pharmacogenetics of Drug Metabolism , pp. 95-178
    • Evans, D.A.1
  • 138
    • 0027281895 scopus 로고
    • Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
    • Hein DW, Doll MA, Rustan TD, Gray K, Feng Y, Fergyson RJ, Grant DM. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 14:1633-1638 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 1633-1638
    • Hein, D.W.1    Doll, Ma.2    Rustan, T.D.3    Gray, K.4    Feng, Y.5    Fergyson, R.J.6    Grant, D.M.7
  • 139
    • 0025344002 scopus 로고
    • Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
    • Blum M, Grant DM, McBride W, Heim M, Meyer UA. Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression. DNA Cell Biol 9:193-203 (1990).
    • (1990) DNA Cell Biol , vol.9 , pp. 193-203
    • Blum, M.1    Grant, D.M.2    McBride, W.3    Heim, M.4    Meyer, U.A.5
  • 140
    • 0015597281 scopus 로고
    • Multiple N-acetyltransferases and and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase
    • Hearse DJ, Weber WW. Multiple N-acetyltransferases and and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem J 132:519-526 (1973).
    • (1973) Biochem J , vol.132 , pp. 519-526
    • Hearse, D.J.1    Weber, W.W.2
  • 142
    • 0027182143 scopus 로고
    • Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 gene locus
    • Vatsis KP, Weber WW. Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus. Arch Biochem Biophys 301:71-76 (1993).
    • (1993) Arch Biochem Biophys , vol.301 , pp. 71-76
    • Vatsis, Kp.1    Weber, W.W.2
  • 143
    • 0025967717 scopus 로고
    • Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
    • Grant DM, Blum M, Beer M, Meyer UA. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. Mol Pharmacol 39:184-191 (1991).
    • (1991) Mol Pharmacol , vol.39 , pp. 184-191
    • Grant, D.M.1    Blum, M.2    Beer, M.3    Meyer, U.A.4
  • 144
    • 0000756778 scopus 로고
    • Detection of a new polymorphism of human arylamine N-acetyltransferase NAT1 using p-aminosalicylic acid as an in vivo probe [abstract]
    • Grant DM, Vohra P, Avis Y, Ima A. Detection of a new polymorphism of human arylamine N-acetyltransferase NAT1 using p-aminosalicylic acid as an in vivo probe [Abstract]. J Basic Clin Physiol Pharmacol 3:S244-(1992).
    • (1992) J Basic Clin Physiol Pharmacol , vol.3
    • Grant, D.M.1    Vohra, P.2    Avis, Y.3    Ima, A.4
  • 145
    • 0344264400 scopus 로고
    • Human liver polymorphic (NAT2) and monomorphic (NAT1) N-acetyltransferase isozymes catalyze metabolic activation of N-hydroxyarylamine and N-hydroxy-N-acetylarylamine proximate carcinogens [abstract]
    • Hein DW, Rustan TD, Grant DM. Human liver polymorphic (NAT2) and monomorphic (NAT1) N-acetyltransferase isozymes catalyze metabolic activation of N-hydroxyarylamine and N-hydroxy-N-acetylarylamine proximate carcinogens [Abstract]. FASEB J 6:A1274 (1992).
    • (1992) FASEB J , vol.6
    • Hein, D.W.1    Rustan, T.D.2    Grant, D.M.3
  • 147
    • 0028979269 scopus 로고
    • N-acetylbenzidine and N,N′-diacetylbenzidine formation by rat and human liver slices exposed to benzidine
    • Lakshmi VM, Bell DA, Watson M, Zenser TV, Davis BB. N-Acetylbenzidine and N,N′-diacetylbenzidine formation by rat and human liver slices exposed to benzidine. Carcinogenesis 16:1565-1571 (1995).
    • (1995) Carcinogenesis , vol.16 , pp. 1565-1571
    • Lakshmi, V.M.1    Bell, D.A.2    Watson, M.3    Zenser, T.V.4    Davis, B.B.5
  • 152
    • 0028844578 scopus 로고
    • Polymorphism in the NAT1 polyadenylation signal: Association of NAT110 allele with higher N-acetylation activity in bladder and colon tissue samples
    • Bell DA, Badavi A, Lang N, llett KF, Kadlubar FF, Hirvonen A. Polymorphism in the NAT1 polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue samples. Cancer Res 55:5226-5229 (1995).
    • (1995) Cancer Res , vol.55 , pp. 5226-5229
    • Bell, D.A.1    Badavi, A.2    Lang, N.3    Llett, K.F.4    Kadlubar, F.F.5    Hirvonen, A.6
  • 153
    • 0028879678 scopus 로고
    • Role of aromatic amine acetyltransferases NAT1 and NAT2, in carcinogen-dna adduct formation in the human urinary bladder
    • Badawi A, Hirvonen A, Bell DA, Lang N, Kadlubar FF. Role of aromatic amine acetyltransferases NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. Cancer Res 55:5230-5237 (1995).
    • (1995) Cancer Res , vol.55 , pp. 5230-5237
    • Badawi, A.1    Hirvonen, A.2    Bell, D.A.3    Lang, N.4    Kadlubar, F.F.5
  • 154
    • 0028240565 scopus 로고
    • Relationship between in vivo acetylator phenotypes and cytosolic N-acetyltransferase and O-acetyltransferase activities in human uroepithelial cells
    • Fredrickson SM, Messing EM, Reznikoff CA, Swaminathan S. Relationship between in vivo acetylator phenotypes and cytosolic N-acetyltransferase and O-acetyltransferase activities in human uroepithelial cells. Cancer Epidemiol Biomarkers Prev 3:25-32 (1994).
    • (1994) Cancer Epidemiol Biomarkers Prev , vol.3 , pp. 25-32
    • Fredrickson, S.M.1    Messing, E.M.2    Reznikoff, C.A.3    Swaminathan, S.4
  • 155
    • 0031573438 scopus 로고    scopus 로고
    • A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) alleles
    • Deitz AC, Doll MA, Hein DW. A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) alleles. Anal Biochem 253:219-224 (1997).
    • (1997) Anal Biochem , vol.253 , pp. 219-224
    • Deitz, A.C.1    Doll, Ma.2    Hein, D.W.3
  • 157
    • 0028270681 scopus 로고
    • Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene
    • Lin H, Han C-Y, Lin BK, Hardy S. Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene. Pharmacogenetics 4:125-134 (1994).
    • (1994) Pharmacogenetics , vol.4 , pp. 125-134
    • Lin, H.1    Han, C.-Y.2    Lin, B.K.3    Hardy, S.4
  • 162
    • 0027373719 scopus 로고
    • Slow acetylator mutations in the human polymorphic N-acetyltransferase gene in 786 Asians, blacks, hispanics, and whites: Application to metabolic epidemiology
    • Lin H, Man C-Y, Lin BK, Hardy S. Slow acetylator mutations in the human polymorphic N-acetyltransferase gene in 786 Asians, Blacks, Hispanics, and Whites: application to metabolic epidemiology. Am J Hum Genet 52:827-834 (1993).
    • (1993) Am J Hum Genet , vol.52 , pp. 827-834
    • Lin, H.1    Man, C.-Y.2    Lin, B.K.3    Hardy, S.4
  • 163
    • 0029163589 scopus 로고
    • Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated caucasian individuals: Correlation with phenotypic
    • Cascorbi I, Drakoulis N, Brockmöller J, Maurer A, Sperling K, Roots I. Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic. Am J Hum Genet 57:581-592 (1995).
    • (1995) Am J Hum Genet , vol.57 , pp. 581-592
    • Cascorbi, I.1    Drakoulis, N.2    Brockmöller, J.3    Maurer, A.4    Sperling, K.5    Roots, I.6
  • 164
    • 0028607112 scopus 로고
    • Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitus
    • Mrozikiewicz PM, Drakoulis N, Roots I. Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitus. Clin Pharmacol Ther 56:626-634 (1994).
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 626-634
    • Mrozikiewicz, P.M.1    Drakoulis, N.2    Roots, I.3
  • 165
    • 0029032229 scopus 로고
    • Inherited GSTM1 and NAT2 defects as concurrent risk modifiers for asbestos-associated human malignant mesothelioma
    • Hirvonen A, Pelin K, Tammilehto L, Karjalainen A, Mattson K, Linnainmaa K. Inherited GSTM1 and NAT2 defects as concurrent risk modifiers for asbestos-associated human malignant mesothelioma. Cancer Res 55:2981-2983 (1995).
    • (1995) Cancer Res , vol.55 , pp. 2981-2983
    • Hirvonen, A.1    Pelin, K.2    Tammilehto, L.3    Karjalainen, A.4    Mattson, K.5    Linnainmaa, K.6
  • 166
    • 0026785642 scopus 로고
    • Molecular genotyping of N-acetylation polymorphism to predict phenotype
    • Mashimo M, Suzuki T, Abe M, Deguchi T. Molecular genotyping of N-acetylation polymorphism to predict phenotype. Hum Genet 90:139-142 (1992).
    • (1992) Hum Genet , vol.90 , pp. 139-142
    • Mashimo, M.1    Suzuki, T.2    Abe, M.3    Deguchi, T.4
  • 168
    • 0013484154 scopus 로고    scopus 로고
    • Polymorphic NATs and cancer proneness
    • Boffetta P, Caporaso N, Cuzick J, Lang M, Vineis P, eds. IARC Sci Publ No 148. Lyon: International Agency for Research on Cancer, in press
    • Hirvonen A (1998) Polymorphic NATs and cancer proneness. In: Metabolic Polymorphisms and Cancer (Boffetta P, Caporaso N, Cuzick J, Lang M, Vineis P, eds). IARC Sci Publ No 148. Lyon: International Agency for Research on Cancer, in press.
    • (1998) Metabolic Polymorphisms and Cancer
    • Hirvonen, A.1
  • 171
    • 0028909978 scopus 로고
    • Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer
    • Risch A, Wallace DMA, Bathers S, Sim E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Hum Mol Genet 4: 231-236 (1995).
    • (1995) Hum Mol Genet , vol.4 , pp. 231-236
    • Risch, A.1    Wallace, D.M.A.2    Bathers, S.3    Sim, E.4
  • 173
    • 0020601991 scopus 로고
    • The association of the slow acetylator phenotype with bladder cancer
    • Evans DAP, Eze LC, Whitney EJ. The association of the slow acetylator phenotype with bladder cancer. J Med Genet 20:330-333 (1983).
    • (1983) J Med Genet , vol.20 , pp. 330-333
    • Evans, D.A.P.1    Eze, L.C.2    Whitney, E.J.3
  • 174
    • 0032529236 scopus 로고    scopus 로고
    • The role of N-acetylation polymorphism in smoking associated bladder cancer: Evidence of a gene-gene exposure three-way interaction
    • Taylor JA, Umbach D, Stephens E, Castranio T, Paulson D, Robertson C, Mohler JL, Bell DA. The role of N-acetylation polymorphism in smoking associated bladder cancer: evidence of a gene-gene exposure three-way interaction. Cancer Res 58:3603-3610 (1998).
    • (1998) Cancer Res , vol.58 , pp. 3603-3610
    • Taylor, J.A.1    Umbach, D.2    Stephens, E.3    Castranio, T.4    Paulson, D.5    Robertson, C.6    Mohler, J.L.7    Bell, D.A.8
  • 175
    • 0026040316 scopus 로고
    • Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon
    • Turesky RJ, Lang NP, Butler MA, Teitel CH, Kadlubar FF. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis 12:1839-1845 (1991).
    • (1991) Carcinogenesis , vol.12 , pp. 1839-1845
    • Turesky, R.J.1    Lang, N.P.2    Butler, M.A.3    Teitel, C.H.4    Kadlubar, F.F.5
  • 177
    • 0028576901 scopus 로고
    • Dietary factors and risk of colon cancer
    • Giovannucci E, Willett WC. Dietary factors and risk of colon cancer, Ann Med 26:443-452 (1994).
    • (1994) Ann Med , vol.26 , pp. 443-452
    • Giovannucci, E.1    Willett, W.C.2
  • 178
    • 0026650976 scopus 로고
    • N-and o-acetylation of aromatic and heterocyclic amine carcinogens in by human monomorphic and polymorphic acetyltransferase expressed in cos-1 cells
    • Minchin RF, Reeves PT, Teitel CH, McManus ME, Mojarrabbi B, llett KF, Kadlubar FF. N-and O-acetylation of aromatic and heterocyclic amine carcinogens in by human monomorphic and polymorphic acetyltransferase expressed in cos-1 cells. Biochem Biophys Res Commun 185:839-844 (1992).
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 839-844
    • Minchin, R.F.1    Reeves, P.T.2    Teitel, Ch.3    McManus, M.E.4    Mojarrabbi, B.5    Llett, K.F.6    Kadlubar, F.F.7
  • 179
    • 0028290229 scopus 로고
    • Stable expression of human CYP1A2 and N-acetyltransferases in chinese hamster CHL cells: Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5]-f-quino-xaline
    • Yanagawa Y, Sawada M, Deguchi T, Gonzalez FJ, Kamataki T. Stable expression of human CYP1A2 and N-acetyltransferases in Chinese hamster CHL cells: mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5]-f-quino-xaline. Cancer Res 54:3422-3427 (1994).
    • (1994) Cancer Res , vol.54 , pp. 3422-3427
    • Yanagawa, Y.1    Sawada, M.2    Deguchi, T.3    Gonzalez, F.J.4    Kamataki, T.5
  • 180
    • 0028949369 scopus 로고
    • Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine n-acetyltransferase isozymes (NAT1 and NAT2) expressed in salmonella typhimurium
    • Wild D, Fesrs W, Michel S, Lord HL, Josephy PD. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium. Carcinogenesis 16:643-548 (1995).
    • (1995) Carcinogenesis , vol.16 , pp. 643-1548
    • Wild, D.1    Fesrs, W.2    Michel, S.3    Lord, H.L.4    Josephy, P.D.5
  • 181
    • 0029039042 scopus 로고
    • Polymorphic drug metabolism: Studies with recombinant Chinese hamster cells and analyses in human populations
    • Yokoi T, Sawada M, Kamataki T. Polymorphic drug metabolism: studies with recombinant Chinese hamster cells and analyses in human populations. Pnarmacogenetics 5.S65-S69 (1995).
    • (1995) Pnarmacogenetics , vol.5
    • Yokoi, T.1    Sawada, M.2    Kamataki, T.3
  • 187
    • 0029837310 scopus 로고    scopus 로고
    • Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer
    • Cascorbi I, Brockmöller J, Mrozikiewicz PM, Bauer S, Loddenkemper R, Roots I. Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. Cancer Res 56:3961-3966 (1996).
    • (1996) Cancer Res , vol.56 , pp. 3961-3966
    • Cascorbi, I.1    Brockmöller, J.2    Mrozikiewicz, P.M.3    Bauer, S.4    Loddenkemper, R.5    Roots, I.6
  • 190
    • 0029795003 scopus 로고    scopus 로고
    • Identification and prevalence study of 17 allelic variants of the human NAT2 gene in a white population
    • Agúndez JAG, Oliveta M, Martinez C, Ladero JM, Benítez J. Identification and prevalence study of 17 allelic variants of the human NAT2 gene in a white population. Pharmacogenetics 6:423-428 (1996).
    • (1996) Pharmacogenetics , vol.6 , pp. 423-428
    • Agúndez, J.A.G.1    Oliveta, M.2    Martinez, C.3    Ladero, J.M.4    Benítez, J.5
  • 191
    • 0028653618 scopus 로고
    • NAD(P)H: Quinone oxidoreductase 1 (DT-diaphorase): Expression, regulation and role in cancer
    • Joseph P, Xie T, Xu Y, Jaiswal AK. NAD(P)H: quinone oxidoreductase 1 (DT-diaphorase): expression, regulation and role in cancer. Oncol Res 6:525-532 (1994).
    • (1994) Oncol Res , vol.6 , pp. 525-532
    • Joseph, P.1    Xie, T.2    Xu, Y.3    Jaiswal, A.K.4
  • 192
  • 193
    • 0026505943 scopus 로고
    • NAD(P)H:Quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of mutation which modulates DT-diaphorase activity and mitomycin sensitivity
    • Traver RD, Horikoshi T, Danenberg PV, Ross D, Gibson NW. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res 52:797-802 (1992).
    • (1992) Cancer Res , vol.52 , pp. 797-802
    • Traver, R.D.1    Horikoshi, T.2    Danenberg, P.V.3    Ross, D.4    Gibson, N.W.5
  • 194
    • 0028467127 scopus 로고
    • Loss of heterozygosity at the NAD(P)H:Quinone oxidoreductase locus associated with increased resistance against mitomycin C in human bladder carcinoma cell line
    • Eickelman P, Schulz WA, Rohde D, Schmitz-Drager B, Sies H. Loss of heterozygosity at the NAD(P)H:quinone oxidoreductase locus associated with increased resistance against mitomycin C in human bladder carcinoma cell line. Biol Chem Hoppe Seyler 375:439-445 (1994).
    • (1994) Biol Chem Hoppe Seyler , vol.375 , pp. 439-445
    • Eickelman, P.1    Schulz, W.A.2    Rohde, D.3    Schmitz-Drager, B.4    Sies, H.5
  • 195
    • 0029073531 scopus 로고
    • Identification of an NAD(P)H: Quinone oxidoreductase polymorphism and its association with lung cancer and smoking
    • Rosvold EA, McGlynn KA, Lustbader ED, Buetow KH. Identification of an NAD(P)H: quinone oxidoreductase polymorphism and its association with lung cancer and smoking. Pharmacogenetics 5:199-206 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 199-206
    • Rosvold, E.A.1    McGlynn, K.A.2    Lustbader, E.D.3    Buetow, K.H.4
  • 197
    • 0025799465 scopus 로고
    • Dt-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family
    • Marshall RS, Paterson MC, Rauth AM. DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family. Carcinogenesis 12:1175-1180 (1991).
    • (1991) Carcinogenesis , vol.12 , pp. 1175-1180
    • Marshall, R.S.1    Paterson, M.C.2    Rauth, A.M.3
  • 198
    • 0029636702 scopus 로고
    • Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer
    • Kolesar JM, Kuhn JG, Burris HA III. Detection of a point mutation in NQO1 (DT-diaphorase) in a patient with colon cancer. J Natl Cancer Inst 87:1022-1024 (1995).
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1022-1024
    • Kolesar, J.M.1    Kuhn, J.G.2    Burris H.A., III.3
  • 199
    • 0021064492 scopus 로고
    • Cigarette smoking and lung destruction: Accumulation of neutrophils in the lungs of cigarette smokers
    • Hunninghake GW, Crystal RG. Cigarette smoking and lung destruction: accumulation of neutrophils in the lungs of cigarette smokers. Annu Rev Respir Dis 128:833-838 (1990).
    • (1990) Annu Rev Respir Dis , vol.128 , pp. 833-838
    • Hunninghake, G.W.1    Crystal, R.G.2
  • 200
    • 0025327989 scopus 로고
    • Myeloperoxidase in human lung lavage. II: Internalization of myeloperoxidase by alveolar macrophages
    • Schmekel B, Hornblad Y, Linden M, Sundström C, Venge P. Myeloperoxidase in human lung lavage. II: Internalization of myeloperoxidase by alveolar macrophages. Inflammation 14: 455-461 (1990).
    • (1990) Inflammation , vol.14 , pp. 455-461
    • Schmekel, B.1    Hornblad, Y.2    Linden, M.3    Sundström, C.4    Venge, P.5
  • 202
    • 0025922974 scopus 로고
    • Activation of (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to diolepoxides by human polymorphonuclear leucocytes or myeloperoxidase
    • Mallet WG, Mosebrook DR, Trush MA. Activation of (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to diolepoxides by human polymorphonuclear leucocytes or myeloperoxidase. Carcinogenesis 12:521-524 (1991).
    • (1991) Carcinogenesis , vol.12 , pp. 521-524
    • Mallet, W.G.1    Mosebrook, D.R.2    Trush, Ma.3
  • 203
    • 0030716240 scopus 로고    scopus 로고
    • Myeloperoxidase genetic polymorphism and lung cancer risk
    • London SJ, Lehman TA, Taylor JA. Myeloperoxidase genetic polymorphism and lung cancer risk. Cancer res 57:5001-5003 (1997).
    • (1997) Cancer Res , vol.57 , pp. 5001-5003
    • London, S.J.1    Lehman, T.A.2    Taylor, J.A.3
  • 204
    • 0028250438 scopus 로고
    • Carcinogen activation by sulfate conjugate formation
    • Michejda CJ, Kroeger, Koepke MB. Carcinogen activation by sulfate conjugate formation. Adv Pharmacol 27:331-363 (1994).
    • (1994) Adv Pharmacol , vol.27 , pp. 331-363
    • Michejda, C.J.1    Koepke, M.B.2
  • 205
    • 0027134662 scopus 로고
    • The glucuronidation of hydroxylated metabolites of benzo(a)pyrene and 2-acetylaminofluorene by cDNA expressed human UDP-glucuronocyltransferases
    • Jin CJ, Miners JO, Burchell B, MacKenzie PI. The glucuronidation of hydroxylated metabolites of benzo(a)pyrene and 2-acetylaminofluorene by cDNA expressed human UDP-glucuronocyltransferases. Carcinogenesis 14:2637-2639 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 2637-2639
    • Jin, C.J.1    Miners, J.O.2    Burchell, B.3    Mackenzie, P.I.4
  • 206
    • 0027402335 scopus 로고
    • Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5′-diphosphate glucuronocyltransferases
    • Mackenzie Pi, Rodbourn L, Iyanagi T. Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5′-diphosphate glucuronocyltransferases. Cancer Res 53:1529-1533 (1993).
    • (1993) Cancer Res , vol.53 , pp. 1529-1533
    • Mackenzie, P.1    Rodbourn, L.2    Iyanagi, T.3
  • 208
    • 0028833732 scopus 로고
    • Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation
    • Owens IS, Ritter JK. Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation. Prog Nucleic Acid Res Mol Biol 51:205-338 (1995).
    • (1995) Prog Nucleic Acid Res Mol Biol , vol.51 , pp. 205-338
    • Owens, I.S.1    Ritter, J.K.2
  • 209
    • 0028265810 scopus 로고
    • The mammalian flavin-containing monooxygenases: Molecular characterization and regulation of expression
    • Hines RN, Cashman JR, Philpot RM, Williams DE, Ziegler DM. The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. Toxicol Appl Pharmacol 125:1-6 (1994).
    • (1994) Toxicol Appl Pharmacol , vol.125 , pp. 1-6
    • Hines, R.N.1    Cashman, J.R.2    Philpot, R.M.3    Williams, D.E.4    Ziegler, D.M.5


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