Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: A distinct nucleotide specificity of the C-terminal ATP-binding site

European Journal of Biochemistry

Volumn 270, Issue 11, 2003, Pages 2421-2428

  Soti, Csaba ^a   Vermes, Ákos ^a   Haystead, Timothy A J ^b   Csermely, Péter ^a  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alarmones; Hsp90; Molecular chaperone; NAD; Nucleotide analogs

Indexed keywords

2',3' O (2,4,6 TRINITROPHENYL)NUCLEOTIDE; ADENOSINE; ADENOSINE TRIPHOSPHATE; DIADENOSINE POLYPHOSPHATE; GUANOSINE TRIPHOSPHATE; HEAT SHOCK PROTEIN 90; NICOTINAMIDE ADENINE DINUCLEOTIDE; NUCLEOTIDE BINDING PROTEIN; NUCLEOTIDE DERIVATIVE; PROTEIN INHIBITOR; PURINE NUCLEOTIDE; PYRIMIDINE NUCLEOTIDE; PYROPHOSPHATE; TRINITROPHENYL; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CHELATING AGENTS; HSP90 HEAT-SHOCK PROTEINS; LIVER; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; NUCLEOTIDES; PHOSPHATES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SEPHAROSE; SUBSTRATE SPECIFICITY;

EID: 0038730655     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03610.x     Document Type: Article

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