Biochemical and structural studies of the interaction of Cdc37 with Hsp90

Journal of Molecular Biology

Volumn 340, Issue 4, 2004, Pages 891-907

  Zhang, Wei ^a   Hirshberg, Miriam ^a,d   McLaughlin, Stephen H ^a   Lazar, Greg A ^a,c   Grossmann, J Günter ^b   Nielsen, Peter R ^a   Sobott, Frank ^a   Robinson, Carol V ^a   Jackson, Sophie E ^a   Laue, Ernest D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b DARESBURY LABORATORY   (United Kingdom)

^c Xencor Inc   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

ATPase activity; AUC, analytical ultracentrifugation; GA, geldanamycin; heat shock protein; kinase; molecular chaperone; protein protein interaction; SAXS, small angle X ray scattering; SEC, size exclusion chromatography; TPR, tetratricopeptide repeat

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 37; CHAPERONE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE 9; HEAT SHOCK PROTEIN 90; PROTEIN KINASE; PROTEIN KINASE B; RAF PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HYDROLYSIS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RADIATION SCATTERING; SIGNAL TRANSDUCTION;

EID: 3042598511     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.05.007     Document Type: Article

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