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Volumn 74, Issue 1, 2010, Pages 55-66

Application of Electron Paramagnetic Resonance (EPR) spectroscopy and imaging in drug delivery research - Chances and challenges

Author keywords

Drug delivery; Electron Paramagnetic Resonance; Electron Spin Resonance; EPR; EPR imaging; ESR; In vivo

Indexed keywords

CHEMICAL COMPOUND; CHITOSAN; DRUG CARRIER; NITROXIDE DERIVATIVE; POLYGLACTIN;

EID: 72149125040     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.08.007     Document Type: Article
Times cited : (77)

References (73)
  • 1
    • 0011342679 scopus 로고
    • Paramagnetic absorption of a solution in parallel fields
    • Zavoiskii E. Paramagnetic absorption of a solution in parallel fields. Journal of Physics 8 (1944) 377-380
    • (1944) Journal of Physics , vol.8 , pp. 377-380
    • Zavoiskii, E.1
  • 5
    • 20444372674 scopus 로고    scopus 로고
    • Monitoring drug delivery processes by EPR and related techniques - principles and applications
    • Lurie D.J., and Mäder K. Monitoring drug delivery processes by EPR and related techniques - principles and applications. Advanced Drug Delivery Reviews 57 (2005) 1171-1190
    • (2005) Advanced Drug Delivery Reviews , vol.57 , pp. 1171-1190
    • Lurie, D.J.1    Mäder, K.2
  • 6
    • 33745825926 scopus 로고    scopus 로고
    • Electron paramagnetic resonance (EPR) spectroscopy: a versatile and powerful tool in pharmaceutical and biomedical analysis
    • Carini M., Aldini G., Orioli M., and Facino R.M. Electron paramagnetic resonance (EPR) spectroscopy: a versatile and powerful tool in pharmaceutical and biomedical analysis. Current Pharmaceutical Analysis 2 (2006) 141-159
    • (2006) Current Pharmaceutical Analysis , vol.2 , pp. 141-159
    • Carini, M.1    Aldini, G.2    Orioli, M.3    Facino, R.M.4
  • 7
    • 0032491083 scopus 로고    scopus 로고
    • Water binding of polysaccharides - NMR and ESR studies
    • Lüsse S., and Arnold K. Water binding of polysaccharides - NMR and ESR studies. Macromolecules 31 (1998) 6891-6897
    • (1998) Macromolecules , vol.31 , pp. 6891-6897
    • Lüsse, S.1    Arnold, K.2
  • 8
    • 33344472675 scopus 로고    scopus 로고
    • Loading and mobility of spin-labeled insulin in physiologically responsive complexation hydrogels intended for oral administration
    • Besheer A., Wood K.M., Peppas N.A., and Mäder K. Loading and mobility of spin-labeled insulin in physiologically responsive complexation hydrogels intended for oral administration. Journal of Controlled Release 111 (2006) 73-80
    • (2006) Journal of Controlled Release , vol.111 , pp. 73-80
    • Besheer, A.1    Wood, K.M.2    Peppas, N.A.3    Mäder, K.4
  • 9
    • 0031751359 scopus 로고    scopus 로고
    • Monitoring microviscosity and microacidity of the albumin microenvironment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethyleneoxide) B blocks
    • Mäder K., Bittner B., Li Y.X., Wohlauf W., and Kissel T. Monitoring microviscosity and microacidity of the albumin microenvironment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethyleneoxide) B blocks. Pharmaceutical Research 15 (1998) 787-793
    • (1998) Pharmaceutical Research , vol.15 , pp. 787-793
    • Mäder, K.1    Bittner, B.2    Li, Y.X.3    Wohlauf, W.4    Kissel, T.5
  • 10
    • 20744455833 scopus 로고    scopus 로고
    • An electrochemical and ESR spectroscopic study on the molecular dynamics of TEMPO in room temperature ionic liquid solvents
    • Evans R.G., Wain A.J., Hardcare C., and Compton R.G. An electrochemical and ESR spectroscopic study on the molecular dynamics of TEMPO in room temperature ionic liquid solvents. ChemPhysChem 6 (2005) 1035-1039
    • (2005) ChemPhysChem , vol.6 , pp. 1035-1039
    • Evans, R.G.1    Wain, A.J.2    Hardcare, C.3    Compton, R.G.4
  • 11
    • 0000326938 scopus 로고    scopus 로고
    • Nonlinear-least-squares analysis of slow-motion EPR spectra in one and two dimensions using a modified Levenberg-Marquardt algorithm
    • Budil D.E., Lee S., Saxena S., and Freed J.H. Nonlinear-least-squares analysis of slow-motion EPR spectra in one and two dimensions using a modified Levenberg-Marquardt algorithm. Journal of Magnetic Resonance, Series A 120 (1996) 155-189
    • (1996) Journal of Magnetic Resonance, Series A , vol.120 , pp. 155-189
    • Budil, D.E.1    Lee, S.2    Saxena, S.3    Freed, J.H.4
  • 13
    • 19944390994 scopus 로고    scopus 로고
    • Biological imaging and spectroscopy of pH
    • Khramtsov V.V. Biological imaging and spectroscopy of pH. Current Organic Chemistry 9 (2005) 909-923
    • (2005) Current Organic Chemistry , vol.9 , pp. 909-923
    • Khramtsov, V.V.1
  • 16
    • 34447500409 scopus 로고    scopus 로고
    • 2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies
    • 2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies. Antioxidants & Redox Signaling 9 (2007) 1169-1182
    • (2007) Antioxidants & Redox Signaling , vol.9 , pp. 1169-1182
    • Khan, N.1    William, B.B.2    Hou, H.3    Li, H.4    Swartz, H.M.5
  • 18
    • 4644283094 scopus 로고    scopus 로고
    • Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications
    • Gallez B., Baudelet C., and Jordan B.F. Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications. NMR in Biomedicine 17 (2004) 240-262
    • (2004) NMR in Biomedicine , vol.17 , pp. 240-262
    • Gallez, B.1    Baudelet, C.2    Jordan, B.F.3
  • 19
    • 1642542351 scopus 로고    scopus 로고
    • Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption
    • Jordan B.F., Sonveaux P., Feron O., Gregoire V., Beghein N., Dessy C., and Gallez B. Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption. International Journal of Cancer 109 (2004) 768-773
    • (2004) International Journal of Cancer , vol.109 , pp. 768-773
    • Jordan, B.F.1    Sonveaux, P.2    Feron, O.3    Gregoire, V.4    Beghein, N.5    Dessy, C.6    Gallez, B.7
  • 20
    • 0028918306 scopus 로고
    • In vivo detection of anthralin-derived free-radicals in the skin of hairless mice by low-frequency electron-paramagnetic-resonance spectroscopy
    • Mäder K., Bacic G., and Swartz H.M. In vivo detection of anthralin-derived free-radicals in the skin of hairless mice by low-frequency electron-paramagnetic-resonance spectroscopy. Journal of Investigative Dermatology 104 (1995) 514-517
    • (1995) Journal of Investigative Dermatology , vol.104 , pp. 514-517
    • Mäder, K.1    Bacic, G.2    Swartz, H.M.3
  • 22
    • 30744460128 scopus 로고    scopus 로고
    • Electron paramagnetic resonance spectroscopy studies of oxidative degradation of an active pharmaceutical ingredient and quantitative analysis of the organic radical intermediates using partial least-squares regression
    • Williams H.E., Loades V.C., Claybourn M., and Murphy D.M. Electron paramagnetic resonance spectroscopy studies of oxidative degradation of an active pharmaceutical ingredient and quantitative analysis of the organic radical intermediates using partial least-squares regression. Analytical Chemistry 78 (2006) 604-608
    • (2006) Analytical Chemistry , vol.78 , pp. 604-608
    • Williams, H.E.1    Loades, V.C.2    Claybourn, M.3    Murphy, D.M.4
  • 23
    • 30644471434 scopus 로고    scopus 로고
    • Study of gamma-irradiation effects on chitosan microparticles
    • Desai K.G., and Park H.J. Study of gamma-irradiation effects on chitosan microparticles. Drug Delivery 13 (2006) 39-50
    • (2006) Drug Delivery , vol.13 , pp. 39-50
    • Desai, K.G.1    Park, H.J.2
  • 25
    • 28244495873 scopus 로고    scopus 로고
    • An EPR and ENDOR study of γ- and β-radiation sterilization in poly(lactide-co-glycolide) polymers and microspheres
    • Bushell J.A., Claybourn M., Williams H.E., and Murphy D.M. An EPR and ENDOR study of γ- and β-radiation sterilization in poly(lactide-co-glycolide) polymers and microspheres. Journal of Controlled Release 110 (2005) 49-57
    • (2005) Journal of Controlled Release , vol.110 , pp. 49-57
    • Bushell, J.A.1    Claybourn, M.2    Williams, H.E.3    Murphy, D.M.4
  • 26
    • 0030294052 scopus 로고    scopus 로고
    • Gamma-sterilization-induced radicals in biodegradable drug delivery systems
    • Mäder K., Domb A., and Swartz H.M. Gamma-sterilization-induced radicals in biodegradable drug delivery systems. Applied Radiation and Isotopes 47 (1996) 1669-1674
    • (1996) Applied Radiation and Isotopes , vol.47 , pp. 1669-1674
    • Mäder, K.1    Domb, A.2    Swartz, H.M.3
  • 27
    • 0032146515 scopus 로고    scopus 로고
    • ESR spectroscopy applied to study of pharmaceuticals radiosterilization: cefoperazone
    • Basly J.P., Basly I., and Bernard M. ESR spectroscopy applied to study of pharmaceuticals radiosterilization: cefoperazone. Journal of Pharmaceutical Sciences 17 (1998) 871-875
    • (1998) Journal of Pharmaceutical Sciences , vol.17 , pp. 871-875
    • Basly, J.P.1    Basly, I.2    Bernard, M.3
  • 28
    • 0042125467 scopus 로고    scopus 로고
    • Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study
    • Jores K., Mehnert W., and Mäder K. Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study. Pharmaceutical Research 20 (2003) 1274-1283
    • (2003) Pharmaceutical Research , vol.20 , pp. 1274-1283
    • Jores, K.1    Mehnert, W.2    Mäder, K.3
  • 31
    • 21644461152 scopus 로고    scopus 로고
    • In vivo ESR studies on subcutaneously injected multilamellar liposomes in living mice
    • Moll K.P., Stösser R., Herrmann W., Borchert H.H., and Utsumi H. In vivo ESR studies on subcutaneously injected multilamellar liposomes in living mice. Pharmaceutical Research 21 (2004) 2017-2024
    • (2004) Pharmaceutical Research , vol.21 , pp. 2017-2024
    • Moll, K.P.1    Stösser, R.2    Herrmann, W.3    Borchert, H.H.4    Utsumi, H.5
  • 32
    • 44449108861 scopus 로고    scopus 로고
    • Electron spin resonance study on the dynamics of polymeric nanocapsules
    • Rübe A., and Mäder K. Electron spin resonance study on the dynamics of polymeric nanocapsules. Journal of Biomedical Nanotechnology 1 (2005) 208-213
    • (2005) Journal of Biomedical Nanotechnology , vol.1 , pp. 208-213
    • Rübe, A.1    Mäder, K.2
  • 33
    • 58249105092 scopus 로고    scopus 로고
    • ESR studies on the influence of physiological dissolution and digestion media on the lipid phase characteristics of SEDDS and SEDDS pellets
    • Abdalla A., and Mäder K. ESR studies on the influence of physiological dissolution and digestion media on the lipid phase characteristics of SEDDS and SEDDS pellets. International Journal of Pharmaceutics 367 (2009) 29-36
    • (2009) International Journal of Pharmaceutics , vol.367 , pp. 29-36
    • Abdalla, A.1    Mäder, K.2
  • 34
    • 33750595542 scopus 로고    scopus 로고
    • Monitoring of in vitro fat digestion by electron paramagnetic resonance spectroscopy
    • Rübe A., Klein S., and Mäder K. Monitoring of in vitro fat digestion by electron paramagnetic resonance spectroscopy. Pharmaceutical Research 23 (2006) 2024-2029
    • (2006) Pharmaceutical Research , vol.23 , pp. 2024-2029
    • Rübe, A.1    Klein, S.2    Mäder, K.3
  • 37
    • 0041718431 scopus 로고    scopus 로고
    • Non-invasive in vivo characterization of release processes in biodegradable polymers by low-frequency electron paramagnetic resonance spectroscopy
    • Mäder K., Gallez B., Liu K.J., and Swartz H.M. Non-invasive in vivo characterization of release processes in biodegradable polymers by low-frequency electron paramagnetic resonance spectroscopy. Biomaterials 17 (1996) 457-461
    • (1996) Biomaterials , vol.17 , pp. 457-461
    • Mäder, K.1    Gallez, B.2    Liu, K.J.3    Swartz, H.M.4
  • 38
    • 0030636181 scopus 로고    scopus 로고
    • Noninvasive in vivo monitoring of drug release and polymer erosion from biodegradable polymers by EPR spectroscopy and NMR imaging
    • Mäder K., Bacic G., Domb A., Elmalak O., Langer R., and Swartz H.M. Noninvasive in vivo monitoring of drug release and polymer erosion from biodegradable polymers by EPR spectroscopy and NMR imaging. Journal of Pharmaceutical Sciences 86 (1997) 126-134
    • (1997) Journal of Pharmaceutical Sciences , vol.86 , pp. 126-134
    • Mäder, K.1    Bacic, G.2    Domb, A.3    Elmalak, O.4    Langer, R.5    Swartz, H.M.6
  • 39
    • 17344386713 scopus 로고    scopus 로고
    • Correlation between drug release kinetics from proteineous matrix and matrix structure: EPR and NMR study
    • Katzhendler I., Mäder K., and Friedman M. Correlation between drug release kinetics from proteineous matrix and matrix structure: EPR and NMR study. Journal of Pharmaceutical Sciences 89 (2000) 365-381
    • (2000) Journal of Pharmaceutical Sciences , vol.89 , pp. 365-381
    • Katzhendler, I.1    Mäder, K.2    Friedman, M.3
  • 40
    • 50949132230 scopus 로고    scopus 로고
    • Do in situ forming PLG/NMP implants behave similar in vitro and in vivo? A non-invasive and quantitative EPR investigation on the mechanism of the implant formation process
    • Kempe S., Metz H., and Mäder K. Do in situ forming PLG/NMP implants behave similar in vitro and in vivo? A non-invasive and quantitative EPR investigation on the mechanism of the implant formation process. Journal of Controlled Release 130 (2008) 220-225
    • (2008) Journal of Controlled Release , vol.130 , pp. 220-225
    • Kempe, S.1    Metz, H.2    Mäder, K.3
  • 41
    • 0030959633 scopus 로고    scopus 로고
    • In vitro in vivo comparison of drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides - a noninvasive approach by the combined use of electron paramagnetic resonance spectroscopy and nuclear magnetic resonance imaging
    • Mäder K., Cremmilleux Y., Domb A.J., Dunn J.F., and Swartz H.M. In vitro in vivo comparison of drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides - a noninvasive approach by the combined use of electron paramagnetic resonance spectroscopy and nuclear magnetic resonance imaging. Pharmaceutical Research 14 (1997) 820-826
    • (1997) Pharmaceutical Research , vol.14 , pp. 820-826
    • Mäder, K.1    Cremmilleux, Y.2    Domb, A.J.3    Dunn, J.F.4    Swartz, H.M.5
  • 44
    • 0028964135 scopus 로고
    • Direct and continuous determination of pH values in nontransparent W/O systems by means of EPR spectroscopy
    • Kroll C., Mäder K., Stosser R., and Borchert H.H. Direct and continuous determination of pH values in nontransparent W/O systems by means of EPR spectroscopy. European Journal of Pharmaceutical Sciences 3 (1995) 21-26
    • (1995) European Journal of Pharmaceutical Sciences , vol.3 , pp. 21-26
    • Kroll, C.1    Mäder, K.2    Stosser, R.3    Borchert, H.H.4
  • 45
    • 0033026897 scopus 로고    scopus 로고
    • pH and osmotic pressure inside biodegradable microspheres during erosion
    • Brunner A., Mäder K., and Göpferich A. pH and osmotic pressure inside biodegradable microspheres during erosion. Pharmaceutical Research 16 (1999) 847-853
    • (1999) Pharmaceutical Research , vol.16 , pp. 847-853
    • Brunner, A.1    Mäder, K.2    Göpferich, A.3
  • 47
    • 0031236840 scopus 로고    scopus 로고
    • Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging
    • Mäder K., Nitschke S., Stosser R., Borchert H.H., and Domb A. Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging. Polymer 38 (1997) 4785-4794
    • (1997) Polymer , vol.38 , pp. 4785-4794
    • Mäder, K.1    Nitschke, S.2    Stosser, R.3    Borchert, H.H.4    Domb, A.5
  • 48
    • 0034949010 scopus 로고    scopus 로고
    • Influence of drug treatment on the microacidity in rat and human skin - an in vitro electron spin resonance imaging study
    • Kroll C., Herrmann W., Stösser R., Borchert H.H., and Mäder K. Influence of drug treatment on the microacidity in rat and human skin - an in vitro electron spin resonance imaging study. Pharmaceutical Research 18 (2001) 525-530
    • (2001) Pharmaceutical Research , vol.18 , pp. 525-530
    • Kroll, C.1    Herrmann, W.2    Stösser, R.3    Borchert, H.H.4    Mäder, K.5
  • 49
    • 0029858642 scopus 로고    scopus 로고
    • Noninvasive measurement of the pH inside the gut by using pH-sensitive nitroxides. An in vivo EPR study
    • Gallez B., Mäder K., and Swartz H.M. Noninvasive measurement of the pH inside the gut by using pH-sensitive nitroxides. An in vivo EPR study. Magnetic Resonance in Medicine 36 (1996) 694-697
    • (1996) Magnetic Resonance in Medicine , vol.36 , pp. 694-697
    • Gallez, B.1    Mäder, K.2    Swartz, H.M.3
  • 51
    • 47249114004 scopus 로고    scopus 로고
    • Changes of the properties in the upper layers of human skin on treatment with models of different pharmaceutical formulations - an ex vivo ESR imaging study
    • Moll K.P., Herrmann W., Stosser R., and Borchert H.H. Changes of the properties in the upper layers of human skin on treatment with models of different pharmaceutical formulations - an ex vivo ESR imaging study. ChemMedChem 3 (2008) 653-659
    • (2008) ChemMedChem , vol.3 , pp. 653-659
    • Moll, K.P.1    Herrmann, W.2    Stosser, R.3    Borchert, H.H.4
  • 52
    • 0036295051 scopus 로고    scopus 로고
    • Kinetic measurements using EPR imaging with a modulated field gradient
    • Herrling T., Fuchs J., and Groth N. Kinetic measurements using EPR imaging with a modulated field gradient. Journal of Magnetic Resonance 154 (2002) 6-14
    • (2002) Journal of Magnetic Resonance , vol.154 , pp. 6-14
    • Herrling, T.1    Fuchs, J.2    Groth, N.3
  • 53
    • 0025858908 scopus 로고
    • EPR-studies of the penetration of water into polymer foils and microparticles on the base of biodegradable polyesters
    • Mäder K., Stosser R., Borchert H.H., Mank R., and Nerlich B. EPR-studies of the penetration of water into polymer foils and microparticles on the base of biodegradable polyesters. Pharmazie 46 (1991) 342-345
    • (1991) Pharmazie , vol.46 , pp. 342-345
    • Mäder, K.1    Stosser, R.2    Borchert, H.H.3    Mank, R.4    Nerlich, B.5
  • 54
    • 0031236840 scopus 로고    scopus 로고
    • Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging
    • Mäder K., Nitschke S., Stösser R., Borchert H.H., and Domb A. Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging. Polymer 38 (1997) 4785-4794
    • (1997) Polymer , vol.38 , pp. 4785-4794
    • Mäder, K.1    Nitschke, S.2    Stösser, R.3    Borchert, H.H.4    Domb, A.5
  • 55
    • 33344472821 scopus 로고    scopus 로고
    • Electron spin resonance microscopy applied to the study of controlled drug release
    • Blank A., Freed J.H., and Wang C.H. Electron spin resonance microscopy applied to the study of controlled drug release. Journal of Controlled Release 111 (2009) 174-184
    • (2009) Journal of Controlled Release , vol.111 , pp. 174-184
    • Blank, A.1    Freed, J.H.2    Wang, C.H.3
  • 56
    • 5244303063 scopus 로고
    • Electron spin resonance imaging of paramagnetic centres in solids
    • Hoch M.J.R. Electron spin resonance imaging of paramagnetic centres in solids. Journal of Physical Chemistry 14 (1981) 5659-5666
    • (1981) Journal of Physical Chemistry , vol.14 , pp. 5659-5666
    • Hoch, M.J.R.1
  • 58
    • 85052562960 scopus 로고    scopus 로고
    • Spectral-spatial imaging
    • Eaton G.R., Eaton S.S., and Ohno K. (Eds), CRC Press Inc., Boston
    • Maltempo M.M., Eaton S.S., and Eaton G.R. Spectral-spatial imaging. In: Eaton G.R., Eaton S.S., and Ohno K. (Eds). EPR Imaging and In Vivo EPR vol. 14 (2008), CRC Press Inc., Boston 135-143
    • (2008) EPR Imaging and In Vivo EPR , vol.14 , pp. 135-143
    • Maltempo, M.M.1    Eaton, S.S.2    Eaton, G.R.3
  • 60
    • 72149113896 scopus 로고    scopus 로고
    • Spectral-spatial EPR Imaging of drug delivery systems
    • Columbus, Ohio, USA
    • H. Metz and K. Mäder, Spectral-spatial EPR Imaging of drug delivery systems, in: EPR 2005, Columbus, Ohio, USA, 2005, p. 130.
    • (2005) EPR , pp. 130
    • Metz, H.1    Mäder, K.2
  • 63
    • 84870941741 scopus 로고
    • ESR imaging: spatial deconvolution in the presence of an asymmetric hyperfine structure
    • Sotgiu A., Gazzillo D., and Momo F. ESR imaging: spatial deconvolution in the presence of an asymmetric hyperfine structure. Journal of Physics C: Solid State Physics 20 (1987) 6297-6340
    • (1987) Journal of Physics C: Solid State Physics , vol.20 , pp. 6297-6340
    • Sotgiu, A.1    Gazzillo, D.2    Momo, F.3
  • 64
    • 0042592948 scopus 로고    scopus 로고
    • Deconvolution algorithm based on automatic cutoff frequency selection for EPR imaging
    • Deng Y.M., He G.L., Kuppusamy P., and Zweier J.L. Deconvolution algorithm based on automatic cutoff frequency selection for EPR imaging. Magnetic Resonance in Medicine 50 (2003) 444-448
    • (2003) Magnetic Resonance in Medicine , vol.50 , pp. 444-448
    • Deng, Y.M.1    He, G.L.2    Kuppusamy, P.3    Zweier, J.L.4
  • 65
    • 52649142711 scopus 로고    scopus 로고
    • Highly stable dendritic trityl radicals as oxygen and pH probe
    • Liu Y., Villamena F.A., and Zweier J.L. Highly stable dendritic trityl radicals as oxygen and pH probe. Chemical Communications (2008) 4336-4338
    • (2008) Chemical Communications , pp. 4336-4338
    • Liu, Y.1    Villamena, F.A.2    Zweier, J.L.3
  • 66
    • 47949103472 scopus 로고    scopus 로고
    • Synthesis of two persistent fluorinated tetrathiatriarylmethyl (TAM) radicals for biomedical EPR applications
    • Driesshaert B., Charlier N., Gallez B., and Marchand-Brynaert J. Synthesis of two persistent fluorinated tetrathiatriarylmethyl (TAM) radicals for biomedical EPR applications. Bioorganic & Medicinal Chemistry Letters 18 (2008) 4291-4293
    • (2008) Bioorganic & Medicinal Chemistry Letters , vol.18 , pp. 4291-4293
    • Driesshaert, B.1    Charlier, N.2    Gallez, B.3    Marchand-Brynaert, J.4
  • 67
    • 49449107741 scopus 로고    scopus 로고
    • Synthesis and characterization of amino derivatives of persistent trityl radicals as dual function pH and oxygen paramagnetic probes
    • Dhimitruka I., Bobko A.A., Hadad C.M., Zweier J.L., and Khramtsov V.V. Synthesis and characterization of amino derivatives of persistent trityl radicals as dual function pH and oxygen paramagnetic probes. Journal of the American Chemical Society 130 (2008) 10780-10787
    • (2008) Journal of the American Chemical Society , vol.130 , pp. 10780-10787
    • Dhimitruka, I.1    Bobko, A.A.2    Hadad, C.M.3    Zweier, J.L.4    Khramtsov, V.V.5
  • 73
    • 44649156284 scopus 로고    scopus 로고
    • Evaluation of oxygen-responsive times of phthalocyanine-based crystalline paramagnetic spin probes for EPR oximetry
    • Vikram D.S., Ahmad R., Pandian R.P., Petryakov S., and Kuppusamy P. Evaluation of oxygen-responsive times of phthalocyanine-based crystalline paramagnetic spin probes for EPR oximetry. Journal of Magnetic Resonance 193 (2008) 127-132
    • (2008) Journal of Magnetic Resonance , vol.193 , pp. 127-132
    • Vikram, D.S.1    Ahmad, R.2    Pandian, R.P.3    Petryakov, S.4    Kuppusamy, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.