Electron paramagnetic resonance spectroscopy studies of oxidative degradation of an active pharmaceutical ingredient and quantitative analysis of the organic radical intermediates using partial least-squares regression

Analytical Chemistry

Volumn 78, Issue 2, 2006, Pages 604-608

  Williams, Helen Elizabeth ^a   Loades, Victoria Catherine ^a   Claybourn, Mike ^a   Murphy, Damien Martin ^b  

^a ASTRAZENECA   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON PARAMAGNETIC RESONANCE (EPR) SPECTROSCOPY; OXIDATIVE DEGRADATION; PARTIAL LEAST-SQUARES REGRESSION;

CARBON; CHEMICAL ANALYSIS; DEGRADATION; ERROR ANALYSIS; ORGANIC COMPOUNDS; OXIDATION; SPECTRUM ANALYSIS;

ELECTRON RESONANCE;

ARTICLE; CORRELATION ANALYSIS; DEGRADATION KINETICS; ELECTRON NUCLEAR DOUBLE RESONANCE; ELECTRON SPIN RESONANCE; OXIDATION KINETICS; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; SIGNAL NOISE RATIO;

ALCOHOLS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; LEAST-SQUARES ANALYSIS; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; REGRESSION ANALYSIS;

EID: 30744460128     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac051697f     Document Type: Article

References (33)

1. Lamy-Freund, M. T.; Ferreira, V. F. N.; Schreier, S. J. Antibiot. 1985, 38, 753-757.
2. Auclair, C.; Hyland, K.; Paoletti, C. J. Med. Ckem. 1983, 26, 1438-1444.
3. Vasquez-Vivar, J.; Augusto, O. Free Radical Res. Commun. 1990, 9, 383-389.
4. Cotelle, P.; Vezin, H. Res. Chem. Intermediates 2003, 29, 365-377.
5. Takemura, O.; Oka, K.; Uchida, M.; Kawasaki, Y.; Kakimi, Y. Proc. Congr.-Eur Brew. Conv. 1997, 26th, 545-552.
6. Kaneda, H.; Kano, Y.; Osawa, T.; Kawakishi, S.; Kamada, K. J. Am. Soc. Brew. Chem. 1989, 47, 49-53.
7. Forster, C.; Schwieger, J.; Narziss, L.; Back, W.; Uchida, M.; Ono, M.; Yanagi, K. Monatsschr. Brauwiss. 1999, 52, 86-93.
8. Uchida, M.; Suga, S.; Ono, M. J. Am. Soc. Brew. Chem. 1996, 54, 205-211.
9. Stasko, A.; Rapta, P.; Malik, F. Monatsschr. Brauwiss. 2000, 53, 4-7.
10. Velasco, J.; Andersen, M. L.; Skibsted, L. H. Food Chem. 2004, 85, 623-632.
11. Kristensen, D.; Andersen, M. L.; Skibsted, L. H. Milchwissenschaft 2002, 57, 255-258.
12. Kristensen, D.; Kroger-Ohlsen, M. V.; Skibsted, L. H. ACS Symp. Ser. 2002, 807, 114-125.
13. Thomsen, M. K.; Vedstesen, H.; Skibsted, L. H. J. Food Lipids 1999, 6, 149-158.
14. Thomsen, M. K.; Kristensen, D.; Skibsted, L. H. J. Am. Oil Chem. Soc. 2000, 77, 725-730.
15. Carlsen, C. U.; Andersen, M. L.; Skibsted, L. H. Eur. Food Res. Technol. 2001, 213, 170-173.
16. Hasegawa, A.; Hamano, T.; Miwa, M.; Nagasaka, S. Dent. Mater. J. 1999, 18, 207-217.
17. Basly, J. P.; Duroux, J. L.; Bernard, M. Int. J. Pharm. 1996, 139, 219-221.
18. Basly, J. P.; Longy, I.; Bernard, M. Pharm. Res. 1997, 14, 1192-1196.
19. Basly, J. P.; Basly, I.; Bernard, M. J. Pharm. Biomed. Anal. 1998, 17, 871-875.
20. Ambroz, H. B.; Kornacka, E. M.; Marciniec, B.; Ogrodowczyk, M.; Przybytniak, G. K. Radiat. Phys. Chem. 2000, 58, 357-366.
21. Nagy, V. Appl. Magn. Reson. 1994, 6, 259-285.
22. Koskinen, J. R.; Kowalski, B. R. ACS Symp. Ser. 1977, 52, 117-126.
23. Attanasio, D. Appl. Magn. Reson. 1999, 16, 383-402.
24. Steinbock, O.; Neumann, B.; Cage, B.; Saltiel, J.; Muller, S. C.; Dalal, N. S. Anal. Chem. 1997, 69, 3708-3713.
25. Karlström, H.; Norden, B.; Wikander, G. Soil Sci. 1994, 157, 300-311.
26. Geladi, P.; Kowalski, B. R. Anal. Chim. Acta 1986, 185, 1-17.
27. Brereton, R. G. Chemometrics: Data Analysis for the Laboratory and Chemical Plant, 1st ed.; Wiley: Chichester, 2003.
28. Attwood, A. L.; Edwards, J. L.; Rowlands, C. C.; Murphy, D. M. J. Phys. Chem. A 2003, 107, 1779-1782.
29. Hovorka, S. W.; Schöneich, C. J. Pharm. Sci. 2001, 90, 253-269.
30. Smith, G. B.; DiMichele, L.; Colwell, L. F., Jr.; Dezeny, G. C.; Douglas, A. W.; Reamer, R. A.; Verhoeven, T. R. Tetrahedron 1993, 49, 4447-4462.
31. Ingold, K. U. Acc. Chem. Res. 1969, 2, 1-9.
32. Stewart, P. J.; Tucker, I. G. Aust. J. Hosp. Pharm. 1985, 15, 111-117.
33. Waterman, K. C.; Adami, R. C.; Alsante, K. M.; Hong, J.; Landis, M. S.; Lombardo, F.; Roberts, C. J. Pharm. Dev. Technol. 2002, 7, 1-32.