메뉴 건너뛰기




Volumn 8, Issue 9, 2009, Pages 1409-1420

Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint

Author keywords

DNA double strand break; DNA replication; PCNA

Indexed keywords

CAFFEINE; CTIP PROTEIN; CYCLINE; DOUBLE STRANDED DNA; DOXYCYCLINE; HISTONE H2AX; MUTANT PROTEIN; NUCLEAR PROTEIN; PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG;

EID: 65949113598     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.9.8322     Document Type: Article
Times cited : (23)

References (33)
  • 1
    • 0032502782 scopus 로고    scopus 로고
    • Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif
    • DOI 10.1074/jbc.273.15.8549
    • Schaeper U, Subramanian T, Lim L, Boyd JM, Chinnadurai G. Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J Biol Chem 1998; 273:8549-8552 (Pubitemid 28176126)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.15 , pp. 8549-8552
    • Schaeper, U.1    Subramanian, T.2    Lim, L.3    Boyd, J.M.4    Chinnadurai, G.5
  • 2
    • 0032144027 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel retinoblastoma- Binding protein
    • DOI 10.1006/geno.1998.5368
    • Fusco C, Reymond A, Zervos AS. Molecular cloning and characterization of a novel retinoblastoma-binding protein. Genomics 1998; 51:351-358 (Pubitemid 28413201)
    • (1998) Genomics , vol.51 , Issue.3 , pp. 351-358
    • Fusco, C.1    Reymond, A.2    Zervos, A.S.3
  • 4
    • 7844246154 scopus 로고    scopus 로고
    • Characterization of a carboxy-terminal BRCA1 interacting protein
    • Wong AK, Ormonde PA, Pero R, Chen Y, Lian L, Salada G, et al. Characterization of a carboxy-terminal BRCA1 interacting protein. Oncogene 1998; 17:2279-2285
    • (1998) Oncogene , vol.17 , pp. 2279-2285
    • Wong, A.K.1    Ormonde, P.A.2    Pero, R.3    Chen, Y.4    Lian, L.5    Salada, G.6
  • 5
    • 0032566753 scopus 로고    scopus 로고
    • The C-terminal (BRCT) domains of BRCA1 interact in vive with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
    • DOI 10.1074/jbc.273.39.25388
    • Yu X, Wu LC, Bowcock AM, Aronheim A, Baer R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J Biol Chem 1998; 273:25388-25392 (Pubitemid 28443306)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.39 , pp. 25388-25392
    • Yu, X.1    Wu, L.C.2    Bowcock, A.M.3    Aronheim, A.4    Baer, R.5
  • 6
    • 3042593642 scopus 로고    scopus 로고
    • Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif
    • Dubin MJ, Stokes PH, Sum EY, Williams RS, Valova VA, Robinson PJ, et al. Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif. J Biol Chem 2004; 279:26932-26938
    • (2004) J Biol Chem , vol.279 , pp. 26932-26938
    • Dubin, M.J.1    Stokes, P.H.2    Sum, E.Y.3    Williams, R.S.4    Valova, V.A.5    Robinson, P.J.6
  • 7
    • 0036190459 scopus 로고    scopus 로고
    • CtBP, an unconventional transcriptional torepressor in development and oncogenesis
    • DOI 10.1016/S1097-2765(02)00443-4
    • Chinnadurai G. CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol Cell Biol 2002; 9:213-224 (Pubitemid 34195548)
    • (2002) Molecular Cell , vol.9 , Issue.2 , pp. 213-224
    • Chinnadurai, G.1
  • 8
    • 0033574543 scopus 로고    scopus 로고
    • Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage
    • Li S, Chen PL, Subramanian T, Chinnadurai G, Tomlinson G, Osborne CK, et al. Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J Biol Chem 1999; 274:11334-11348
    • (1999) J Biol Chem , vol.274 , pp. 11334-11348
    • Li, S.1    Chen, P.L.2    Subramanian, T.3    Chinnadurai, G.4    Tomlinson, G.5    Osborne, C.K.6
  • 9
    • 6344264992 scopus 로고    scopus 로고
    • DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
    • DOI 10.1128/MCB.24.21.9478-9486.2004
    • Yu X, Chen J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol Cell Biol 2004; 24:9478-9486 (Pubitemid 39391684)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.21 , pp. 9478-9486
    • Yu, X.1    Chen, J.2
  • 10
    • 33745713176 scopus 로고    scopus 로고
    • Removal of BRCA1/CtIP/ ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature
    • Furuta S, Wang JM, Wei S, Jeng YM, Jiang X, Gu B, et al. Removal of BRCA1/CtIP/ ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature. Cancer Cell 2006; 10:13-24.
    • (2006) Cancer Cell , vol.10 , pp. 13-24
    • Furuta, S.1    Wang, J.M.2    Wei, S.3    Jeng, Y.M.4    Jiang, X.5    Gu, B.6
  • 11
    • 29944434644 scopus 로고    scopus 로고
    • Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
    • DOI 10.1101/gad.1381306
    • Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev 2006; 20:34-46. (Pubitemid 43042666)
    • (2006) Genes and Development , vol.20 , Issue.1 , pp. 34-46
    • Greenberg, R.A.1    Sobhian, B.2    Pathania, S.3    Cantor, S.B.4    Nakatani, Y.5    Livingston, D.M.6
  • 14
    • 34948872046 scopus 로고    scopus 로고
    • Ctp1 Is a Cell-Cycle-Regulated Protein that Functions with Mre11 Complex to Control Double-Strand Break Repair by Homologous Recombination
    • DOI 10.1016/j.molcel.2007.09.009, PII S1097276507006211
    • Limbo O, Chahwan C, Yamada Y, de Bruin RA, Wittenberg C, Russell P. Ctp1 is a cell cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell Biol 2007; 28:134-146 (Pubitemid 47531975)
    • (2007) Molecular Cell , vol.28 , Issue.1 , pp. 134-146
    • Limbo, O.1    Chahwan, C.2    Yamada, Y.3    De Bruin, R.A.M.4    Wittenberg, C.5    Russell, P.6
  • 15
    • 37149043618 scopus 로고    scopus 로고
    • A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination
    • Penkner A, Portik-Dobos Z, Tang L, Schnabel R, Novatchkova M, Jantsch V, et al. A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J 2007; 26:5071-5182
    • (2007) EMBO J , vol.26 , pp. 5071-5182
    • Penkner, A.1    Portik-Dobos, Z.2    Tang, L.3    Schnabel, R.4    Novatchkova, M.5    Jantsch, V.6
  • 16
    • 43149118369 scopus 로고    scopus 로고
    • Cell cycle-dependent complex formation of BRCA1. CtIP.MRN is important for DNA double-strand break repair
    • Chen L, Nievera CJ, Lee AY, Wu X. Cell cycle-dependent complex formation of BRCA1. CtIP.MRN is important for DNA double-strand break repair. J Biol Chem 2008; 283:7713-7720
    • (2008) J Biol Chem , vol.283 , pp. 7713-7720
    • Chen, L.1    Nievera, C.J.2    Lee, A.Y.3    Wu, X.4
  • 17
    • 17644375501 scopus 로고    scopus 로고
    • Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency
    • Chen PL, Liu F, Cai S, Lin X, Li A, Chen Y, et al. Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol Cell Biol 2005; 25:3535-3542
    • (2005) Mol Cell Biol , vol.25 , pp. 3535-3542
    • Chen, P.L.1    Liu, F.2    Cai, S.3    Lin, X.4    Li, A.5    Chen, Y.6
  • 18
    • 0041885325 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen (PCNA): A dancer with many partners
    • DOI 10.1242/jcs.00653
    • Maga G, Hubscher U. Proliferating cell nuclear antigen (PCNA): a dancer with many partners. J Cell Sci 2003; 116:3051-3060 (Pubitemid 37038954)
    • (2003) Journal of Cell Science , vol.116 , Issue.15 , pp. 3051-3060
    • Maga, G.1    Hubscher, U.2
  • 19
    • 0028618183 scopus 로고
    • Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
    • Krishna TS, Kong XP, Gary S, Burgers PM, Kuriyan J. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell 1994; 79:1233-1243
    • (1994) Cell , vol.79 , pp. 1233-1243
    • Krishna, T.S.1    Kong, X.P.2    Gary, S.3    Burgers, P.M.4    Kuriyan, J.5
  • 20
    • 0034723152 scopus 로고    scopus 로고
    • DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading
    • Maga G, Stucki M, Spadari , Hübscher U. DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. J Mol Biol 2000; 295:791-801.
    • (2000) J Mol Biol , vol.295 , pp. 791-801
    • Maga, G.1    Stucki, M.2    Spadari3    Hübscher, U.4
  • 21
    • 27544445683 scopus 로고    scopus 로고
    • The DNA damage response during DNA replication
    • DOI 10.1016/j.ceb.2005.09.003, PII S0955067405001420
    • Branzei D, Foiani M. The DNA damage response during DNA replication. Curr Opin Cell Biol 2005; 17:568-575 (Pubitemid 41541967)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.6 , pp. 568-575
    • Branzei, D.1    Foiani, M.2
  • 22
  • 23
    • 0032031972 scopus 로고    scopus 로고
    • PCNA binding through a conserved motif
    • DOI 10.1002/(SICI)1521-1878(199803)20:3<195::AID-BIES2>3.0.CO;2-R
    • Warbrick E. PCNA binding through a conserved motif. Bioessays 1998; 20:195-199 (Pubitemid 28174030)
    • (1998) BioEssays , vol.20 , Issue.3 , pp. 195-199
    • Warbrick, E.1
  • 24
    • 34249937178 scopus 로고    scopus 로고
    • The ATR pathway: Fine-tuning the fork
    • DOI 10.1016/j.dnarep.2007.02.015, PII S1568786407000651, Replication Fork Repair Processes
    • Paulsen RD, Cimprich KA. The ATR pathway: fine-tuning the fork. DNA Repair 2007; 6:953-966 (Pubitemid 46880476)
    • (2007) DNA Repair , vol.6 , Issue.7 , pp. 953-966
    • Paulsen, R.D.1    Cimprich, K.A.2
  • 26
    • 0027311843 scopus 로고
    • Visualization of replication factories attached to a nucleoskeleton
    • DOI 10.1016/0092-8674(93)90235-I
    • Hozák P, Hassan AB, Jackson DA, Cook PR. Visualization of replication factories attached to nucleoskeleton. Cell 1993; 73:361-373 (Pubitemid 23123313)
    • (1993) Cell , vol.73 , Issue.2 , pp. 361-373
    • Hozak, P.1    Hassan, A.B.2    Jackson, D.A.3    Cook, P.R.4
  • 27
    • 0033777562 scopus 로고    scopus 로고
    • The puzzle of PCNA's many partners
    • Warbrick E. The puzzle of PCNA's many partners. Bioessays 2000; 22:997-1006.
    • (2000) Bioessays , vol.22 , pp. 997-1006
    • Warbrick, E.1
  • 28
    • 0037178740 scopus 로고    scopus 로고
    • Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
    • Sogo JM, Lopes M, Foiani M. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 2002; 297:599-602.
    • (2002) Science , vol.297 , pp. 599-602
    • Sogo, J.M.1    Lopes, M.2    Foiani, M.3
  • 29
    • 0037178723 scopus 로고    scopus 로고
    • ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
    • Cha RS, Kleckner N. ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 2002; 297:602-606
    • (2002) Science , vol.297 , pp. 602-606
    • Cha, R.S.1    Kleckner, N.2
  • 30
    • 0037224965 scopus 로고    scopus 로고
    • Checkpoint activation regulates mutagenic translesion synthesis
    • DOI 10.1101/gad.1043203
    • Kai M, Wang TS. Checkpoint activation regulates mutagenic translesion synthesis. Genes Dev 2003; 17:64-76. (Pubitemid 36062509)
    • (2003) Genes and Development , vol.17 , Issue.1 , pp. 64-76
    • Kai, M.1    Wang, T.S.-F.2
  • 31
    • 0032702679 scopus 로고    scopus 로고
    • Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control
    • Chen CF, Chen PL, Zhong Q, Sharp ZD, Lee WH. Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control. J Biol Chem 1999; 274:32931-32935
    • (1999) J Biol Chem , vol.274 , pp. 32931-32935
    • Chen, C.F.1    Chen, P.L.2    Zhong, Q.3    Sharp, Z.D.4    Lee, W.H.5
  • 32
    • 0034730633 scopus 로고    scopus 로고
    • Chen NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
    • Wu G, Lee WH, Chen PL. Chen NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J Biol Chem 2000; 275:30618-30622
    • (2000) J Biol Chem , vol.275 , pp. 30618-30622
    • Wu, G.1    Lee, W.H.2    Chen, P.L.3
  • 33
    • 0027251721 scopus 로고
    • The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
    • Durfee T, Becherer K, Chen PL, Yeh SH, Yang Y, Kilburn AE, et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev 1993; 7:555-569
    • (1993) Genes Dev , vol.7 , pp. 555-569
    • Durfee, T.1    Becherer, K.2    Chen, P.L.3    Yeh, S.H.4    Yang, Y.5    Kilburn, A.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.