SCOPUS 정보 검색 플랫폼

Volumn 38, Issue 11, 2009, Pages 1009-1019

Osteoblasts. Cellular and molecular regulatory mechanisms in fracture healing;Osteoblasten. Zelluläre und molekulare Regulationsmechanismen in der Frakturheilung

(7) Hofmann, A a Mattyasovszky, S G a Bruning C a Ritz, U a Mehling, I a Meurer, A b Rommens, P M a

a JOHANNES GUTENBERG UNIVERSITY (Germany)

b UNIVERSITY HOSPITAL FRANKFURT (Germany)

Author keywords

Differentiation; Fracture healing; Osteoblast; RUNX2; WNT

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; LYMPHOID ENHANCER FACTOR 1; OSTEONECTIN; OSTEOPONTIN; SCLEROSTIN; SECRETED FRIZZLED RELATED PROTEIN 1; SMAD4 PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

BONE GROWTH; CELL DIFFERENTIATION; DOWN REGULATION; FRACTURE HEALING; FRACTURE NONUNION; HUMAN; NONHUMAN; OSSIFICATION; OSTEOBLAST; PROTEIN EXPRESSION; REVIEW;

ANIMALS; BONE AND BONES; FRACTURE HEALING; FRACTURES, BONE; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; OSTEOBLASTS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 71049173247 PISSN: 00854530 EISSN: None Source Type: Journal
DOI: 10.1007/s00132-009-1488-5 Document Type: Review

Times cited : (8)

References (58)

1
- 10744224854
- High Bone Mass in Mice Expressing a Mutant LRP5 Gene
- DOI 10.1359/jbmr.2003.18.6.960
- Babij 2003 J Bone Miner Res 6 960 10.1359/jbmr.2003.18.6.960 (Pubitemid 37294932)
- (2003) Journal of Bone and Mineral Research , vol.18 , Issue.6 , pp. 960-974
- Babij, P.¹ Zhao, W.² Small, C.³ Kharode, Y.⁴ Yaworsky, P.J.⁵ Bouxsein, M.L.⁶ Reddy, P.S.⁷ Bodine, P.V.⁸ Robinson, J.A.⁹ Bhat, B.¹⁰ Marzolf, J.¹¹ Moran, R.A.¹² Bex, F.¹³

2
- 68949099454
- 10.1016/j.bone.2009.06.015 19540374
- Bajada 2009 Bone 45 726 10.1016/j.bone.2009.06.015 19540374
- (2009) Bone , vol.45 , pp. 726
- Bajada¹

3
- 0031733876
- 10.1097/00003086-199810001-00025
- Bruder 1998 Clin Orthop Relat Res 355 247 10.1097/00003086-199810001- 00025
- (1998) Clin Orthop Relat Res , vol.355 , pp. 247
- Bruder¹

4
- 0025062505
- Bone formation by osteoblast-like cells in a three-dimensional cell culture
- DOI 10.1007/BF02555824
- Casser-Bette 1990 Calcif Tissue Int 1 46 10.1007/BF02555824 (Pubitemid 20045654)
- (1990) Calcified Tissue International , vol.46 , Issue.1 , pp. 46-56
- Casser-Bette, M.¹ Murray, A.B.² Closs, E.I.³ Erfle, V.⁴ Schmidt, J.⁵

5
- 34547604106
- Beta-catenin signaling plays a disparate role in different phases of fracture repair: Implications for therapy to improve bone healing
- DOI 10.1371/journal.pmed.0040249
- Chen 2007 PLoS Med 7 249 10.1371/journal.pmed.0040249 (Pubitemid 47196225)
- (2007) PLoS Medicine , vol.4 , Issue.7 , pp. 1216-1229
- Chen, Y.¹ Whetstone, H.C.² Lin, A.C.³ Nadesan, P.⁴ Wei, Q.⁵ Poon, R.⁶ Alman, B.A.⁷

6
- 33846987195
- Chen 2007 J Biol Chem 1 526
- (2007) J Biol Chem , vol.1 , pp. 526
- Chen¹

7
- 71049178412
- D 1999 Development 13 2911
- (1999) Development , vol.13 , pp. 2911

8
- 33847303506
- Health economics: A cost analysis of treatment of persistent fracture non-unions using bone morphogenetic protein-7
- DOI 10.1016/j.injury.2006.08.055, PII S0020138306005456
- Dahabreh 2007 Injury 3 371 10.1016/j.injury.2006.08.055 (Pubitemid 46328913)
- (2007) Injury , vol.38 , Issue.3 , pp. 371-377
- Dahabreh, Z.¹ Dimitriou, R.² Giannoudis, P.V.³

9
- 17844372752
- Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
- DOI 10.1016/j.devcel.2005.03.016, PII S1534580705001061
- Day 2005 Dev Cell 5 739 10.1016/j.devcel.2005.03.016 (Pubitemid 40585296)
- (2005) Developmental Cell , vol.8 , Issue.5 , pp. 739-750
- Day, T.F.¹ Guo, X.² Garrett-Beal, L.³ Yang, Y.⁴

10
- 0141737573
- 10.1016/S0092-8674(00)81558-5
- Ducy 2000 Cell 2 197 10.1016/S0092-8674(00)81558-5
- (2000) Cell , vol.2 , pp. 197
- Ducy¹

11
- 15844412402
- Increased bone formation in osteocalcin-deficient mice
- DOI 10.1038/382448a0
- Ducy 1996 Nature 6590 448 10.1038/382448a0 (Pubitemid 26264860)
- (1996) Nature , vol.382 , Issue.6590 , pp. 448-452
- Ducy, P.¹ Desbois, C.² Boyce, B.³ Pinero, G.⁴ Story, B.⁵ Dunstan, C.⁶ Smith, E.⁷ Bonadio, J.⁸ Goldstein, S.⁹ Gundberg, C.¹⁰ Bradley, A.¹¹ Karsenty, G.¹²

12
- 0034285013
- The osteoblast: A sophisticated fibroblast under central surveillance
- DOI 10.1126/science.289.5484.1501
- Ducy 2000 Science 5484 1501 10.1126/science.289.5484.1501 (Pubitemid 30677463)
- (2000) Science , vol.289 , Issue.5484 , pp. 1501-1504
- Ducy, P.¹ Schinke, T.² Karsenty, G.³

13
- 0030678549
- 10.1016/S0092-8674(00)80257-3
- Ducy 1997 Cell 5 747 10.1016/S0092-8674(00)80257-3
- (1997) Cell , vol.5 , pp. 747
- Ducy¹

14
- 71049122985
- el 1997 Nat Genet 1 42
- (1997) Nat Genet , vol.1 , pp. 42
- El¹

15
- 0036157079
- Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis
- DOI 10.1002/jcb.10091
- Fischer 2002 J Cell Biochem 4 816 10.1002/jcb.10091 (Pubitemid 34113120)
- (2002) Journal of Cellular Biochemistry , vol.84 , Issue.4 , pp. 816-831
- Fischer, L.¹ Boland, G.² Tuan, R.S.³

16
- 4344643927
- French 2004 Am J Pathol 3 855
- (2004) Am J Pathol , vol.3 , pp. 855
- French¹

17
- 0037119434
- 10.1074/jbc.M203171200
- Hadjiargyrou 2002 J Biol Chem 33 30177 10.1074/jbc.M203171200
- (2002) J Biol Chem , vol.33 , pp. 30177
- Hadjiargyrou¹

18
- 0031763545
- 10.1097/00003086-199810001-00005
- Hayda 1998 Clin Orthop Relat Res 355 31 10.1097/00003086-199810001-00005
- (1998) Clin Orthop Relat Res , vol.355 , pp. 31
- Hayda¹

19
- 20844449569
- TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro
- DOI 10.1359/JBMR.050210
- Hens 2005 J Bone Miner Res 7 1103 10.1359/JBMR.050210 (Pubitemid 40863798)
- (2005) Journal of Bone and Mineral Research , vol.20 , Issue.7 , pp. 1103-1113
- Hens, J.R.¹ Wilson, K.M.² Dann, P.³ Chen, X.⁴ Horowitz, M.C.⁵ Wysolmerski, J.J.⁶

20
- 0012258368
- Hernigou 1997 Rev Chir Orthop Reparat Apparat Mot 1 33
- (1997) Rev Chir Orthop Reparat Apparat Mot , vol.1 , pp. 33
- Hernigou¹

21
- 17844363974
- Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes
- DOI 10.1016/j.devcel.2005.02.013, PII S1534580705000870
- Hill 2005 Dev Cell 5 727 10.1016/j.devcel.2005.02.013 (Pubitemid 40585295)
- (2005) Developmental Cell , vol.8 , Issue.5 , pp. 727-738
- Hill, T.P.¹ Spater, D.² Taketo, M.M.³ Birchmeier, W.⁴ Hartmann, C.⁵

22
- 4344595883
- Hofmann 2004 Unfallchirurg 7 583
- (2004) Unfallchirurg , vol.7 , pp. 583
- Hofmann¹

23
- 41949096901
- 10.1016/j.bone.2008.01.013 18314404
- Hofmann 2008 Bone 42 894 10.1016/j.bone.2008.01.013 18314404
- (2008) Bone , vol.42 , pp. 894
- Hofmann¹

24
- 13444302715
- Hu 2005 Development 1 49
- (2005) Development , vol.1 , pp. 49
- Hu¹

25
- 1542569747
- Smad4 and β-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2
- DOI 10.1074/jbc.M305472200
- Hussein 2003 J Biol Chem 49 48805 10.1074/jbc.M305472200 (Pubitemid 41079523)
- (2003) Journal of Biological Chemistry , vol.278 , Issue.49 , pp. 48805-48814
- Hussein, S.M.¹ Duff, E.K.² Sirard, C.³

26
- 38749144432
- Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures
- DOI 10.1359/jbmr.070724
- Kakar 2007 J Bone Miner Res 12 1903 10.1359/jbmr.070724 (Pubitemid 351229307)
- (2007) Journal of Bone and Mineral Research , vol.22 , Issue.12 , pp. 1903-1912
- Kakar, S.¹ Einhorn, T.A.² Vora, S.³ Miara, L.J.⁴ Hon, G.⁵ Wigner, N.A.⁶ Toben, D.⁷ Jacobsen, K.A.⁸ Al-Sebaei, M.O.⁹ Song, M.¹⁰ Trackman, P.C.¹¹ Morgan, E.F.¹² Gerstenfeld, L.C.¹³ Barnes, G.L.¹⁴

27
- 0037092049
- Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
- DOI 10.1083/jcb.200201089
- Kato 2002 J Cell Biol 2 303 10.1083/jcb.200201089 (Pubitemid 34839826)
- (2002) Journal of Cell Biology , vol.157 , Issue.2 , pp. 303-314
- Kato, M.¹ Patel, M.S.² Levasseur, R.³ Lobov, I.⁴ Chang, B.H.-J.⁵ Glass II, D.A.⁶ Hartmann, C.⁷ Li, L.⁸ Hwang, T.-H.⁹ Brayton, C.F.¹⁰ Lang, R.A.¹¹ Karsenty, G.¹² Chan, L.¹³

28
- 0033014044
- Regulation of chondrocyte differentiation by Cbfa1
- DOI 10.1016/S0925-4773(98)00210-X, PII S092547739800210X
- Kim 1999 Mech Dev 2 159 10.1016/S0925-4773(98)00210-X (Pubitemid 29125427)
- (1999) Mechanisms of Development , vol.80 , Issue.2 , pp. 159-170
- Kim, I.S.¹ Otto, F.² Zabel, B.³ Mundlos, S.⁴

29
- 38749149224
- Bone regeneration is regulated by Wnt signaling
- DOI 10.1359/jbmr.070802
- Kim 2007 J Bone Miner Res 12 1913 10.1359/jbmr.070802 (Pubitemid 351229308)
- (2007) Journal of Bone and Mineral Research , vol.22 , Issue.12 , pp. 1913-1923
- Kim, J.-B.¹ Leucht, P.² Lam, K.³ Luppen, C.⁴ Ten Berge, D.⁵ Nusse, R.⁶ Helms, J.A.⁷

30
- 23844515714
- NFAT and Osterix cooperatively regulate bone formation
- DOI 10.1038/nm1270
- Koga 2005 Nat Med 8 880 10.1038/nm1270 (Pubitemid 41161121)
- (2005) Nature Medicine , vol.11 , Issue.8 , pp. 880-885
- Koga, T.¹ Matsui, Y.² Asagiri, M.³ Kodama, T.⁴ De Crombrugghe, B.⁵ Nakashima, K.⁶ Takayanagi, H.⁷

31
- 0030684749
- 10.1016/S0092-8674(00)80258-5
- Komori 1997 Cell 5 755 10.1016/S0092-8674(00)80258-5
- (1997) Cell , vol.5 , pp. 755
- Komori¹

32
- 2142782630
- 10.1136/mp.52.2.92
- Lawton 1999 Mol Pathol 2 92 10.1136/mp.52.2.92
- (1999) Mol Pathol , vol.2 , pp. 92
- Lawton¹

33
- 0030696216
- 10.1136/mp.50.4.194
- Lawton 1997 Mol Pathol 4 194 10.1136/mp.50.4.194
- (1997) Mol Pathol , vol.4 , pp. 194
- Lawton¹

34
- 33748156090
- Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
- DOI 10.1016/j.bone.2006.03.017, PII S8756328206004078
- Li 2006 Bone 4 754 10.1016/j.bone.2006.03.017 (Pubitemid 44311706)
- (2006) Bone , vol.39 , Issue.4 , pp. 754-766
- Li, J.¹ Sarosi, I.² Cattley, R.C.³ Pretorius, J.⁴ Asuncion, F.⁵ Grisanti, M.⁶ Morony, S.⁷ Adamu, S.⁸ Geng, Z.⁹ Qiu, W.¹⁰ Kostenuik, P.¹¹ Lacey, D.L.¹² Simonet, W.S.¹³ Bolon, B.¹⁴ Qian, X.¹⁵ Shalhoub, V.¹⁶ Ominsky, M.S.¹⁷ Zhu Ke, H.¹⁸ Li, X.¹⁹ Richards, W.G.²⁰ more..

36
- 0017127778
- 10.1126/science.1273593
- Miller 1976 Science 4246 1340 10.1126/science.1273593
- (1976) Science , vol.4246 , pp. 1340
- Miller¹

37
- 33646856033
- Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass
- DOI 10.1359/jbmr.060311
- Morvan 2006 J Bone Miner Res 6 934 10.1359/jbmr.060311 (Pubitemid 43788000)
- (2006) Journal of Bone and Mineral Research , vol.21 , Issue.6 , pp. 934-945
- Morvan, F.¹ Boulukos, K.² Clement-Lacroix, P.³ Roman, S.R.⁴ Suc-Royer, I.⁵ Vayssiere, B.⁶ Ammann, P.⁷ Martin, P.⁸ Pinho, S.⁹ Pognonec, P.¹⁰ Mollat, P.¹¹ Niehrs, C.¹² Baron, R.¹³ Rawadi, G.¹⁴

38
- 15444351110
- 10.1016/S0092-8674(00)80260-3
- Mundlos 1997 Cell 5 773 10.1016/S0092-8674(00)80260-3
- (1997) Cell , vol.5 , pp. 773
- Mundlos¹

39
- 0037059614
- The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
- DOI 10.1016/S0092-8674(01)00622-5
- Nakashima 2002 Cell 1 17 10.1016/S0092-8674(01)00622-5 (Pubitemid 34137009)
- (2002) Cell , vol.108 , Issue.1 , pp. 17-29
- Nakashima, K.¹ Zhou, X.² Kunkel, G.³ Zhang, Z.⁴ Deng, J.M.⁵ Behringer, R.R.⁶ De Crombrugghe, B.⁷

40
- 33646050013
- 10.1016/j.gene.2005.12.022
- Nishio 2006 Gene 10 62 10.1016/j.gene.2005.12.022
- (2006) Gene , vol.10 , pp. 62
- Nishio¹

41
- 0030666372
- 10.1016/S0092-8674(00)80259-7
- Otto 1997 Cell 5 765 10.1016/S0092-8674(00)80259-7
- (1997) Cell , vol.5 , pp. 765
- Otto¹

42
- 0025316785
- Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
- DOI 10.1002/jcp.1041430304
- Owen 1990 J Cell Physiol 3 420 10.1002/jcp.1041430304 (Pubitemid 20201656)
- (1990) Journal of Cellular Physiology , vol.143 , Issue.3 , pp. 420-430
- Owen, T.A.¹ Aronow, M.² Shalhoub, V.³ Barone, L.M.⁴ Wilming, L.⁵ Tassinari, M.S.⁶ Kennedy, M.B.⁷ Pockwinse, S.⁸ Lian, J.B.⁹ Stein, G.S.¹⁰

43
- 0036239197
- Human atrophic fracture non-unions are not avascular
- DOI 10.1016/S0736-0266(01)00142-5, PII S0736026601001425
- Reed 2002 J Orthop Res 3 593 10.1016/S0736-0266(01)00142-5 (Pubitemid 34461020)
- (2002) Journal of Orthopaedic Research , vol.20 , Issue.3 , pp. 593-599
- Reed, A.A.C.¹ Joyner, C.J.² Brownlow, H.C.³ Simpson, A.H.R.W.⁴

44
- 33846026749
- Wnt/β-catenin signaling is a normal physiological response to mechanical loading in bone
- DOI 10.1074/jbc.M602308200
- Robinson 2006 J Biol Chem 42 31720 10.1074/jbc.M602308200 (Pubitemid 46043263)
- (2006) Journal of Biological Chemistry , vol.281 , Issue.42 , pp. 31720-31728
- Robinson, J.A.¹ Chatterjee-Kishore, M.² Yaworsky, P.J.³ Cullen, D.M.⁴ Zhao, W.⁵ Li, C.⁶ Kharode, Y.⁷ Sauter, L.⁸ Babij, P.⁹ Brown, E.L.¹⁰ Hill, A.A.¹¹ Akhter, M.P.¹² Johnson, M.L.¹³ Recker, R.R.¹⁴ Komm, B.S.¹⁵ Bex, F.J.¹⁶

45
- 33748768971
- Distinct roles for Hedgehog and caronical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
- DOI 10.1242/dev.02480
- Rodda 2006 Development 16 3231 10.1242/dev.02480 (Pubitemid 44404346)
- (2006) Development , vol.133 , Issue.16 , pp. 3231-3244
- Rodda, S.J.¹ McMahon, A.P.²

46
- 0033974297
- DOI 10.1007/s001130050008
- Runkel 2000 Unfallchirurg 1 51 10.1007/s001130050008 (Pubitemid 30084210)
- (2000) Unfallchirurg , vol.103 , Issue.1 , pp. 51-63
- Runkel, M.¹ Rommens, P.M.²

47
- 0033220559
- 10.1007/s001040050775
- Ruter 1999 Chirurg 11 1239 10.1007/s001040050775
- (1999) Chirurg , vol.11 , pp. 1239
- Ruter¹

48
- 34247580964
- Number and proliferative capacity of human mesenchymal stem cells are modulated positively in multiple trauma patients and negatively in atrophic nonunions
- DOI 10.1007/s00223-007-9020-6
- Seebach 2007 Calcif Tissue Int 4 294 10.1007/s00223-007-9020-6 (Pubitemid 46675255)
- (2007) Calcified Tissue International , vol.80 , Issue.4 , pp. 294-300
- Seebach, C.¹ Henrich, D.² Tewksbury, R.³ Wilhelm, K.⁴ Marzi, I.⁵

49
- 0032005274
- Reversing the inhibitory effect of nicotine on spinal fusion using an osteoinductive protein extract
- DOI 10.1097/00007632-199802010-00001
- Silcox 1998 Spine 3 291 10.1097/00007632-199802010-00001 (Pubitemid 28109852)
- (1998) Spine , vol.23 , Issue.3 , pp. 291-297
- Silcox III, D.H.¹ Boden, S.D.² Schimandle, J.H.³ Johnson, P.⁴ Whitesides, T.E.⁵ Hutton, W.C.⁶

50
- 33646808104
- Wnt signalling in osteoblasts regulates expression of the receptor activator of NFκB ligand and inhibits osteoclastogenesis in vitro
- DOI 10.1242/jcs.02883
- Spencer 2006 J Cell Sci Pt 7 1283 10.1242/jcs.02883 (Pubitemid 43756545)
- (2006) Journal of Cell Science , vol.119 , Issue.7 , pp. 1283-1296
- Spencer, G.J.¹ Utting, J.C.² Etheridge, S.L.³ Arnett, T.R.⁴ Genever, P.G.⁵

51
- 0017314010
- 10.1007/BF00415452
- Sudmann 1976 Arch Orthop Unfallchir 2 151 10.1007/BF00415452
- (1976) Arch Orthop Unfallchir , vol.2 , pp. 151
- Sudmann¹

52
- 0023899021
- Uchida 1988 Acta Orthop Scand 1 29
- (1988) Acta Orthop Scand , vol.1 , pp. 29
- Uchida¹

53
- 34250019537
- 10.1126/science.150.3698.893
- Urist 1965 Science 698 893 10.1126/science.150.3698.893
- (1965) Science , vol.698 , pp. 893
- Urist¹

54
- 0016737181
- 10.1007/BF02563992
- Urist 1975 Calcif Tissue Res 1 73 10.1007/BF02563992
- (1975) Calcif Tissue Res , vol.1 , pp. 73
- Urist¹

55
- 0017414192
- Urist 1977 Am J Physiol 3 115
- (1977) Am J Physiol , vol.3 , pp. 115
- Urist¹

56
- 5044228112
- Wnt signaling in osteoblasts and bone diseases
- DOI 10.1016/j.gene.2004.06.044, PII S0378111904003853
- Westendorf 2004 Gene 341 19 10.1016/j.gene.2004.06.044 15474285 (Pubitemid 39335880)
- (2004) Gene , vol.341 , Issue.1-2 , pp. 19-39
- Westendorf, J.J.¹ Kahler, R.A.² Schroeder, T.M.³

57
- 0031764841
- 10.1097/00003086-199810001-00009
- Yoo 1998 Clin Orthop Relat Res 355 73 10.1097/00003086-199810001-00009
- (1998) Clin Orthop Relat Res , vol.355 , pp. 73
- Yoo¹

58
- 33744824348
- Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation
- DOI 10.1016/j.bone.2005.12.008, PII S8756328205005338
- Zhong 2006 Bone 1 5 10.1016/j.bone.2005.12.008 (Pubitemid 43831768)
- (2006) Bone , vol.39 , Issue.1 , pp. 5-16
- Zhong, N.¹ Gersch, R.P.² Hadjiargyrou, M.³

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