Regulation of chondrocyte differentiation by Cbfa1

Mechanisms of Development

Volumn 80, Issue 2, 1999, Pages 159-170

  Kim, I S ^a   Otto, F ^b   Zabel, B ^a   Mundlos, S ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cbfa1; Indian hedgehog; Osteoblast differentiation

Indexed keywords

COLLAGEN TYPE 10; OSTEOPONTIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; EMBRYO; EMBRYO DEVELOPMENT; ENCHONDRAL OSSIFICATION; HUMERUS; HYPERTROPHY; MOUSE; NONHUMAN; OSTEOBLAST; PHALANX; PRIORITY JOURNAL; RADIUS; REPORTER GENE; ULNA;

ANIMALIA; ERINACEIDAE; RODENTIA;

EID: 0033014044     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(98)00210-X     Document Type: Article

References (23)

1. Böhme K., Winterhalter K.H., Bruckner P. Terminal differentiation of chondrocytes is a spontaneous process and is arrested by transforming growth factor-β2 and basic fibroblast growth factor in synergy. Exp. Cell Res. 216:1995;191-198.
2. Chung K.S., Park H.H., Ting K., Takita H., Apte S.S., Kuboki Y., Nishimura I. Modulated expression of type X collagen in Meckel's cartilage with different developmental fates. Dev. Biol. 170:1995;387-396.
3. Ducy P., Zhang R., Geoffroy V., Ridall A.L., Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89:1997;747-754.
4. Erlebacher Q., Filvaroff E.H., Gitelman S.E., Derynck R. Toward a molecular understanding of skeletal development. Cell. 80:1995;371-378.
5. Gibson G., Lin D.-L., Roque M. Apoptosis of terminally differentiated chondrocytes in culture. Exp. Cell Res. 233:1997;372-382.
6. Henrique D., Adam J., Myat A., Chitnis A., Lewis J., Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature. 375:1995;787-790.
7. Huang L.-F., Fukai N., Selby P.B., Olsen B.R., Mundlos S. Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Dev. Dyn. 210:1997;33-40.
8. Kahn A.J., Simmons D.J. Chondrocyte-to-osteocyte transformation in grafts of perichondrium-free epiphyseal cartilage. Clin. Orthop. Rel. Res. 129:1977;299-304.
9. Komori T., Yagi H., Nomura S., Yamaguchi A., Sasaki K., Deguchi K., Shimizu Y., Bronson R.T., Gao Y.H., Inada M., Sato M., Okamoto R., Kitamura Y., Yoshiki S., Kishimoto T. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 89:1997;755-764.
10. Lanske B., Karaplis A.C., Lee K., Luz A., Vortkamp A., Pirro A., Karperien M., Defize L.H.K., Ho C., Mulligan R.C., Abou-Samra A.B., Jüppner H., Segre G.V., Kronenberg H.M. PTH/PTHrP receptor in early development and Indian Hedgehog-regulated bone growth. Science. 273:1996;663-666.
11. Lazik A., Liu Yi., Bringas P., Sangiorgi F., Maxson R. A sensitive method for analyzing b-galactosidase reporter gene expression in tissue sections of mouse embryos. Trends Genet. 12:1996;445-447.
12. Long F., Linsenmayer T.F. Regulation of growth region cartilage proliferation and differentiation by perichondrium. Development. 125:1998;1067-1073.
13. Mundlos S. Expression patterns of matrix genes during human skeletal development. Prog. Histochem. Cytochem. 28:1994;1-47.
14. Mundlos S., Huang L.-F., Selby P., Olsen B.R. Cleidocranial dysplasia in mice. Ann. N.Y. Acad. Sci. 785:1996;301-302.
15. Mundlos S., Olsen B.R. Heritable diseases of the skeleton. Part II. Molecular insights into skeletal development-matrix components and their homeostasis. FASEB J. 11:1997;227-233.
16. Mundlos S., Olsen B.R. Heritable diseases of the skeleton. Part I. Molecular insights into skeletal development-transcription factors and signaling pathways. FASEB J. 11:1997;125-132.
17. Mundlos S., Otto F., Mundlos C., Mulliken J.B., Aylsworth A.S., Albright S., Lindhout D., Cole W.G., Henn W., Knoll J.H.M., Owen M.J., Mertelsmann R., Zabel B.U., Olsen B.R. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell. 89:1997;773-779.
18. Otto F., Thornell A.P., Crompton T., Denzel A., Gilmour K.C., Rosewell I.R., Stamp G.W.H., Beddington R.S.P., Mundlos S., Selby P.B., Olsen B.R., Owen M.J. CBFA1, a candidate gene for cleidocranial dysplasia syndrome is essential for osteoblast formation and bone development. Cell. 89:1997;765-771.
19. Roach H.I., Erenpreisa J., Aigner T. Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis. J. Cell Biol. 131:1995;483-494.
20. Thesing C.W., Groot C.G., Wassanaar A.M. Transdifferentiation of hypertrophic chondrocytes into osteoblasts in murine fetal metatarsal bones, induced by co-cultured cerebrum. Bone Miner. 12:1991;25-40.
21. Serra L., Johnson M., Filvaroff E.H., LaBorde J., Sheehan D.M., Derynck R., Moses H.L. Expression of a truncated, kinase-defective TGF-b Type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J. Cell Biol. 139:1997;541-552.
22. Vortkamp A., Lee K., Lanske B., Segre G.V., Kronenberg H.M., Tabin C.J. Regulation of the rate of cartilage differentiation by Indian Hedgehog and PTH-related protein. Science. 273:1996;613-622.
23. Zou H., Wieser R., Massagué J., Niswander L. Distinct roles of type I bone morphogenic protein receptors in the formation and differentiation of cartilage. Genes Dev. 11:1998;2191-2203.