Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis

Journal of Cellular Biochemistry

Volumn 84, Issue 4, 2002, Pages 816-831

  Fischer, Leslie ^a   Boland, Genevieve ^b   Tuan, Rocky S ^b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Cartilage development; GSK 3 ; Lithium; Micromass culture; N cadherin; Wnt signaling

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG; WNT 7A PROTEIN; WNT PROTEIN; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CHONDROGENESIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; BONE MORPHOGENETIC PROTEINS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CADHERINS; CELL LINE; CHONDROGENESIS; CYTOSKELETAL PROTEINS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; LITHIUM; MESODERM; MICE; PROTEIN BIOSYNTHESIS; PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS; ZEBRAFISH PROTEINS;

MURINAE; STAPHYLOCOCCUS PHAGE 3A;

EID: 0036157079     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10091     Document Type: Article

References (53)

1. Cadherin-catenin complex: Protein interactions and their implications for cadherin function
2. β-catenin is a target for the ubiquitin-proteasome pathway
3. Stage-related capacity for limb chondrogenesis in cell culture
4. In vitro and in vivo ihibition of inositol monophosphatase by the bisphosphonate L-690,330
5. Functional interacton of β-catenin with the transcription factor LEF-1
6. Neural and developmental actions of lithium: A unifying hypothesis
7. Nuclear beta-catenin displays GSK-3beta- and APC-independent proteasome sensitivity in melanoma cells
8. Wnt signaling: A common theme in animal development
9. Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2
10. Wnt signaling to β-catenin involves two interactive components
11. Wingless inactivates glycogen synthase kinase-3 via an intracellular signaling pathway which involves a protein kinase C
12. p1B15: A cDNA clone of the rat mRNA encoding cyclophilin
13. Cellular interactions and signaling in cartilage development
14. Formation of cartilage-like spheroids by micromass culture of murine C3H10T1/2 cells upon treatment with transforming growth factor-β1
15. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells. I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures
16. Cell adhesion and signaling mechanisms in BMP-2 induction of mesenchymal chondrogenesis
17. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development
18. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells. II. Stimulation by bone morphogenetic protein-2 requires modulation of N-cadherin expression and function
19. Dual roles of Wnt signaling during chondrogenesis in the chicken limb
20. Activation of the Wnt signaling pathway: A molecular mechanism for lithium action
21. Beta catenin: A common target for regulation of cell adhesion by Wnt-1 and src signaling pathways
22. Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing β-catenin binding to the cell adhesion protein cadherin
23. Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation
24. Distinct Wnt pathways regulating AER and dorsoventral polarity in the chick limb bud
25. Axin prevents Wnt-3a-induced accumulation of β-catenin
26. Inhibiton of GSK-3b leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
27. Wnt signaling: Moving in a new direction
28. Neural cadherin: Role in selective cell-cell adhesion
29. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis
30. Spatiotemporal profile of N-cadherin expression in the developing limb mesenchyme
31. Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis
32. Serine phosphorylation-regulated ubiquitination and degradation of β-catenin
33. An arrow for wingless to take-off
34. The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas
35. Glycogen sythase kinase-3: Functions in oncogenesis and development
36. Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluent inhibition of divison
37. Association of APC gene product with β-catenin
38. Binding of GSK-3b to the APC-β-catenin complex and regulation of complex assembly
39. Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro
40. Inhibition of β-catenin-mediated transactivation by cadherin derivatives
41. Chondrogenesis of limb bud mesenchyme in vitro: Stimulation by cations
42. Lithium influences differentiation and tissue-specific gene expression of mouse embryonic stem (ES) cells in vitro
43. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
44. Biochemical interactions in the Wnt pathway
45. TCF-1-mediated transcription in T lymphocytes: Differential role for glycogen synthase kinase-3 in fibroblasts and T cells
46. A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalyzed phosphorylation of axin and β-catenin
47. Wnt regulation of limb mesenchymal chondrogenesis is accompanied by altered N-cadherin-related functions
48. Involvement of N-cadherin mediated cell adhesion in TGF-b1/BMP-2 stimulation of limb mesenchymal chondrogenesis
49. Effect of TGF-β1 and BMP-2 on limb mesenchyme chondrogenesis in vitro: Modulation of N-cadherin and catenin association
50. Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation
51. N-cadherin expression and signaling in limb mesenchymnal chondrogenesis: Stimulation by poly-L-lysine
52. The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
53. Supression of glycogen synthase kinase activity is not sufficient for leukemia enhancing factor-1 activation