메뉴 건너뛰기




Volumn 4, Issue 11, 2009, Pages

Regulatory function of a novel population of mouse autoantigen-specific Foxp3- regulatory T cells depends on IFN-γ, NO, and contact with target cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE; NITRIC OXIDE; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; HLA ANTIGEN CLASS 2; INTERLEUKIN 10;

EID: 70849083675     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007863     Document Type: Article
Times cited : (9)

References (43)
  • 1
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S (2004) Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22: 531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 2
    • 4444355794 scopus 로고    scopus 로고
    • Regulatory/suppressor T cells in health and disease
    • Shevach EM (2004) Regulatory/suppressor T cells in health and disease. Arthritis Rheum 50: 2721-2724.
    • (2004) Arthritis Rheum , vol.50 , pp. 2721-2724
    • Shevach, E.M.1
  • 3
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler SF (2006) FOXP3: of mice and men. Annu Rev Immunol 24: 209-226.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 4
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra A, Vieira P (2004) Regulatory T cells and mechanisms of immune system control. Nature Medicine 10: 801-805.
    • (2004) Nature Medicine , vol.10 , pp. 801-805
    • O'Garra, A.1    Vieira, P.2
  • 5
    • 18244400088 scopus 로고    scopus 로고
    • Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes
    • Pop SM, Wong CP, Culton DA, Clarke SH, Tisch R (2005) Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. J Exp Med 201: 1333-1346.
    • (2005) J Exp Med , vol.201 , pp. 1333-1346
    • Pop, S.M.1    Wong, C.P.2    Culton, D.A.3    Clarke, S.H.4    Tisch, R.5
  • 6
    • 20944444896 scopus 로고    scopus 로고
    • Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells
    • You S, Belghith M, Cobbold S, Alyanakian MA, Gouarin C, et al. (2005) Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes 54: 1415-1422.
    • (2005) Diabetes , vol.54 , pp. 1415-1422
    • You, S.1    Belghith, M.2    Cobbold, S.3    Alyanakian, M.A.4    Gouarin, C.5
  • 7
    • 17844364504 scopus 로고    scopus 로고
    • Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in T1D
    • Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA (2005) Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in T1D. Diabetes 54: 1407-1414.
    • (2005) Diabetes , vol.54 , pp. 1407-1414
    • Brusko, T.M.1    Wasserfall, C.H.2    Clare-Salzler, M.J.3    Schatz, D.A.4    Atkinson, M.A.5
  • 8
    • 2942692039 scopus 로고    scopus 로고
    • CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM (2004) CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 199: 1467-1477.
    • (2004) J Exp Med , vol.199 , pp. 1467-1477
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3    Toy, P.4    Steinman, R.M.5
  • 9
    • 2942642383 scopus 로고    scopus 로고
    • In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, et al. (2004) In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 199: 1455-1465.
    • (2004) J Exp Med , vol.199 , pp. 1455-1465
    • Tang, Q.1    Henriksen, K.J.2    Bi, M.3    Finger, E.B.4    Szot, G.5
  • 10
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6: 345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 11
    • 1242295282 scopus 로고    scopus 로고
    • Naturally-occurring CD4+CD25+ immuno-regulatory T cells: Central players in the arena of peripheral tolerance
    • Piccirillo CA, Shevach EM (2004) Naturally-occurring CD4+CD25+ immuno-regulatory T cells: central players in the arena of peripheral tolerance. Semin Immunol 16: 81-88.
    • (2004) Semin Immunol , vol.16 , pp. 81-88
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 12
    • 85047692430 scopus 로고    scopus 로고
    • IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
    • O'Garra A, Vieira PL, Vieira P, Goldfeld AE (2004) IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 114: 1372-1378.
    • (2004) J Clin Invest , vol.114 , pp. 1372-1378
    • O'Garra, A.1    Vieira, P.L.2    Vieira, P.3    Goldfeld, A.E.4
  • 13
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F (2001) Regulatory T cells in the control of immune pathology. Nat Immunol 2: 816-822.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 14
    • 0033738329 scopus 로고    scopus 로고
    • The role of different subsets of T regulatory cells in controlling autoimmunity
    • Roncarolo MG, Levings MK (2000) The role of different subsets of T regulatory cells in controlling autoimmunity. Curr Opin Immunol 12: 676-683.
    • (2000) Curr Opin Immunol , vol.12 , pp. 676-683
    • Roncarolo, M.G.1    Levings, M.K.2
  • 15
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, et al. (1997) A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389: 737-742.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5
  • 16
    • 0038783708 scopus 로고    scopus 로고
    • Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes
    • Chen C, Lee W-H, Yun P, Snow P, Liu C-P (2003) Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes. J Immunol 171: 733-744.
    • (2003) J Immunol , vol.171 , pp. 733-744
    • Chen, C.1    Lee, W.-H.2    Yun, P.3    Snow, P.4    Liu, C.-P.5
  • 17
    • 33644834674 scopus 로고    scopus 로고
    • Regulatory T cells can mediate their function through the stimulation of antigen-presenting cells to produce immunosuppressive nitric oxide
    • Chen C, Lee W-H, Zong LW, Liu C-P (2006) Regulatory T cells can mediate their function through the stimulation of antigen-presenting cells to produce immunosuppressive nitric oxide. J Immunol 176: 3449-3460.
    • (2006) J Immunol , vol.176 , pp. 3449-3460
    • Chen, C.1    Lee, W.-H.2    Zong, L.W.3    Liu, C.-P.4
  • 18
    • 9144221452 scopus 로고    scopus 로고
    • Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice
    • You S, Chen C, Lee WH, Brusko T, Atkinson M, et al. (2004) Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice. J Immunol 173: 6777-6785.
    • (2004) J Immunol , vol.173 , pp. 6777-6785
    • You, S.1    Chen, C.2    Lee, W.H.3    Brusko, T.4    Atkinson, M.5
  • 19
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H (2005) Mechanisms of suppression by suppressor T cells. Nat Immunol 6: 338-344.
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • von Boehmer, H.1
  • 21
    • 0037062420 scopus 로고    scopus 로고
    • Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice
    • Hori S, Haury M, Coutinho A, Demengeot J (2002) Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice. Proc Natl Acad Sci USA 99: 8213-8218.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8213-8218
    • Hori, S.1    Haury, M.2    Coutinho, A.3    Demengeot, J.4
  • 23
    • 0037446645 scopus 로고    scopus 로고
    • Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides
    • You S, Chen C, Lee WH, Wu CH, Judkowski V, et al. (2003) Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides. J Immunol 170: 4011-4020.
    • (2003) J Immunol , vol.170 , pp. 4011-4020
    • You, S.1    Chen, C.2    Lee, W.H.3    Wu, C.H.4    Judkowski, V.5
  • 24
    • 0026580530 scopus 로고
    • NOR/Lt mice: MHC-matched diabetes-resistant control strain for NOD mice
    • Prochazka M, Serreze DV, Frankel WN, Leiter EH (1992) NOR/Lt mice: MHC-matched diabetes-resistant control strain for NOD mice. Diabetes 41: 98-106.
    • (1992) Diabetes , vol.41 , pp. 98-106
    • Prochazka, M.1    Serreze, D.V.2    Frankel, W.N.3    Leiter, E.H.4
  • 25
    • 0028033318 scopus 로고
    • Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene
    • Serreze DV, Prochazka M, Reifsnyder PC, Bridgett MM, Leiter EH (1994) Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene. J Exp Med 180: 1553-1558.
    • (1994) J Exp Med , vol.180 , pp. 1553-1558
    • Serreze, D.V.1    Prochazka, M.2    Reifsnyder, P.C.3    Bridgett, M.M.4    Leiter, E.H.5
  • 26
    • 0035863724 scopus 로고    scopus 로고
    • Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 Nonobese diabetic mice
    • Judkowski V, Pinilla C, Schroder K, Tucker L, Sarvetnick N, et al. (2001) Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 Nonobese diabetic mice. J Immunol 166: 908-917.
    • (2001) J Immunol , vol.166 , pp. 908-917
    • Judkowski, V.1    Pinilla, C.2    Schroder, K.3    Tucker, L.4    Sarvetnick, N.5
  • 27
    • 0031010513 scopus 로고    scopus 로고
    • Identification of immunogenic epitopes of GAD 65 presented by Ag7 in non-obese diabetic mice
    • Chao CC, McDevitt HO (1997) Identification of immunogenic epitopes of GAD 65 presented by Ag7 in non-obese diabetic mice. Immunogenetics 46: 29-34.
    • (1997) Immunogenetics , vol.46 , pp. 29-34
    • Chao, C.C.1    McDevitt, H.O.2
  • 28
    • 0037136283 scopus 로고    scopus 로고
    • CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
    • Tarbell KV, Lee M, Ranheim E, Chao CC, Sanna M, et al. (2002) CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J Exp Med 196: 481-492.
    • (2002) J Exp Med , vol.196 , pp. 481-492
    • Tarbell, K.V.1    Lee, M.2    Ranheim, E.3    Chao, C.C.4    Sanna, M.5
  • 29
    • 4644254774 scopus 로고    scopus 로고
    • Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells
    • Kim SK, Tarbell KV, Sanna M, Vadeboncoeur M, Warganich T, et al. (2004) Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells. Proc Natl Acad Sci USA 101: 14204-14209.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14204-14209
    • Kim, S.K.1    Tarbell, K.V.2    Sanna, M.3    Vadeboncoeur, M.4    Warganich, T.5
  • 33
    • 0031456802 scopus 로고    scopus 로고
    • Interferon-g impacts a multiple points during the progression of autoimmune diabetes
    • Wang B, Andre I, Gonzalez A, Katz JD, Aguet M, et al. (1997) Interferon-g impacts a multiple points during the progression of autoimmune diabetes. Proc Natl Acad Sci USA 94: 13844-13849.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13844-13849
    • Wang, B.1    Andre, I.2    Gonzalez, A.3    Katz, J.D.4    Aguet, M.5
  • 34
    • 0034748269 scopus 로고    scopus 로고
    • Blockade of gamma interferon might be beneficial in MS
    • Steinman L (2001) Blockade of gamma interferon might be beneficial in MS. Mult Scler 7: 275-276.
    • (2001) Mult Scler , vol.7 , pp. 275-276
    • Steinman, L.1
  • 37
    • 0036434844 scopus 로고    scopus 로고
    • Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity
    • Rosloniec EF, Latham K, Guedez YB (2002) Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity. Arthritis Res 4: 333-336.
    • (2002) Arthritis Res , vol.4 , pp. 333-336
    • Rosloniec, E.F.1    Latham, K.2    Guedez, Y.B.3
  • 38
    • 67650650890 scopus 로고    scopus 로고
    • Highly purified Th17 cells from BDC2.5 NOD mice convert into Th1-like cells in NOD/SCID recipient mice
    • Bending D, De La Peûa H, Veldhoen M, Phillips JM, Uyttenhove C, et al. (2009) Highly purified Th17 cells from BDC2.5 NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest 119: 565-572.
    • (2009) J Clin Invest , vol.119 , pp. 565-572
    • Bending, D.1    De La Peûa, H.2    Veldhoen, M.3    Phillips, J.M.4    Uyttenhove, C.5
  • 39
    • 60549086638 scopus 로고    scopus 로고
    • Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
    • Martin-Orozco N, Chung Y, Chang SH, Wang YH, Dong C. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur J Immunol 39: 216-224.
    • Eur J Immunol , vol.39 , pp. 216-224
    • Martin-Orozco, N.1    Chung, Y.2    Chang, S.H.3    Wang, Y.H.4    Dong, C.5
  • 40
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • Dong C (2008) TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol 8: 337-348.
    • (2008) Nat Rev Immunol , vol.8 , pp. 337-348
    • Dong, C.1
  • 41
    • 0031795118 scopus 로고    scopus 로고
    • Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthase by macrophages
    • Huang FP, Niedbala W, Wei XQ, Xu D, Feng GJ, et al. (1998) Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthase by macrophages. Eur J Immunol 28: 4062-4070.
    • (1998) Eur J Immunol , vol.28 , pp. 4062-4070
    • Huang, F.P.1    Niedbala, W.2    Wei, X.Q.3    Xu, D.4    Feng, G.J.5
  • 42
    • 0037080021 scopus 로고    scopus 로고
    • Myeloid suppressor lines inhibits T cell responses by an NO-dependent mechanism
    • Mazzoni A, Bronte V, Visintin A, Spitze JH, Apolloni E, et al. (2002) Myeloid suppressor lines inhibits T cell responses by an NO-dependent mechanism. J Immunol 168: 689-695.
    • (2002) J Immunol , vol.168 , pp. 689-695
    • Mazzoni, A.1    Bronte, V.2    Visintin, A.3    Spitze, J.H.4    Apolloni, E.5
  • 43
    • 0032937567 scopus 로고    scopus 로고
    • Nitric oxide inhibits the proliferation of Th1 and 2 lymphocytes without reduction in cytokine secretion
    • Van der Veen RC, Dietlin TA, Pen L, Gray JD (1999) Nitric oxide inhibits the proliferation of Th1 and 2 lymphocytes without reduction in cytokine secretion. Cell Immunol 193: 194-201.
    • (1999) Cell Immunol , vol.193 , pp. 194-201
    • Van der Veen, R.C.1    Dietlin, T.A.2    Pen, L.3    Gray, J.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.