Immunomodulatory properties of interferon-γ: An update

Annals of the New York Academy of Sciences

Volumn 856, Issue , 1998, Pages 22-32

  Billiau, Alfons ^a   Heremans, Hubertine ^a   Vermeire, Kurt ^a   Matthys, Patrick ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIMICROBIAL ACTIVITY; ARTHRITIS; AUTOIMMUNE DISEASE; CELL ADHESION; CONFERENCE PAPER; ENDOTHELIUM CELL; HELPER CELL; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MEDIATOR; MONONUCLEAR PHAGOCYTE; NATURAL KILLER CELL; NONHUMAN; T LYMPHOCYTE;

ANIMALIA;

EID: 0031738704     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb08309.x     Document Type: Article

References (50)

1. YOUNG, H. A. & K. J. HARDY. 1995. Role of interferon-garama in immune cell regulation. J. Leukocyte Biol. 58: 373-381.
2. BILLIAU, A. 1996. Interferon-γ: Biology and role in pathogenesis. F. J. Dixon, Ed.: 61-130. Academic Press. San Diego, California.
3. MARFAING-KOKA, A., O. DEVERGNE, G. GORGONE, A. PORTIER, T. J. SCHALL, P. GALANAUD & D. EMILIE. 1995. Regulation of the production of the RANTES chemokine by endothelial cells: Synergistic induction by IFN-gamma plus TNF-α and inhibition by IL-4 and IL-13. J. Immunol. 154: 1870-1878.
4. LIU, Y. & C. A. J. JANEWAY. 1990. Interferon γ plays a critical role in induced cell death of effector T cell: A possible third mechanism of self-tolerance. J. Exp. Med. 172: 1735-1739.
5. NOVELLI, F., F. DI PIERRO, P. F. DI CELLE, S. BERTINI, P. AFFATICATI, G. GAROTTA & G. FORNI. 1994. Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis. J. Immunol. 152: 496-504.
6. MATTHYS, P., G. FROYEN, S. HUANG, H. SOBIS, J. VAN DAMME, M. AGUET & A. BILLIAU. 1995. Interferon-γ receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis: Protective role of endogenous nitric oxide. J. Immunol. 155: 3823-3829.
7. KELSO, A. 1995. Th1 and Th2 subsets: Paradigms lost? Immunol. Today 16: 374-379.
8. KAWANO, Y., T. NOMA & J. YATA. 1994. Regulation of human IgG subclass production by cytokines: IFN-gamma and IL-6 act antagonistically in the induction of human IgG1 but additively in the induction of IgG2. J. Immunol. 153: 4948-4958.
9. GRAHAM, M. B., D. K. DALTON, D. GILTINAN, V. L. BRACIALE, T. A. STEWART & T. J. BRACIALE. 1993. Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J. Exp. Med. 178: 1725-1732.
10. DOBBER, R., M. TIELEMANS & L. NAGELKERKEN. 1995. The in vivo effects of neutralizing antibodies against IFN-gamma, IL-4, or IL-10 on the humoral immune response in young and aged mice. Cell. Immunol. 160: 185-192.
11. HUANG, S., W. HENDRIKS, A. ALTHAGE, S. HEMMI, H. BLUETHMANN, R. KAMIJO, J. VILCEK, R. M. ZINKERNAGEL & M. AGUET. 1993. Immune response in mice that lack the interferon-gamma receptor. Science 259: 1742-1745.
12. SEDER, R. A., R. GAZZINELLI, A. SHER & W. E. PAUL. 1993. Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90: 10188-10192.
13. HEINZEL, F. P., D. S. SCHOENHAUT, R. M. RERKO, L. E. ROSSER & M. K. GATELY. 1993. Recombinant interleukin-12 cures mice infected with Leishmania major. J. Exp. Med. 177: 1505-1509.
14. WANG, Z.-E., S. ZHENG, D. B. CORRY, D. K. DALTON, R. A. SEDER, S. L. REINER & R. M. LOCKSLEY. 1994. Interferon γ-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major. Proc. Natl. Acad. Sci. USA 91: 12932-12936.
15. TAYLOR, A. P. & H. W. MURRAY. 1997. Intracellular antimicrobial activity in the absence of interferon-γ: Effect of interleukin-12 in experimental Leishmaniasis in interferon-γ gene-disrupted mice. J. Exp. Med. 185: 1231-1239.
16. WYNN, T. A., D. JANKOVIC, S. HIENY, K. ZIONCHECK, P. JARDIEU, A. W. CHEEVER & A. SHER. 1995. IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-γ. J. Immunol. 154: 3999-4009.
17. MCKNIGHT, A. J., G. J. ZIMMER, I. FOGELMAN, S. F. WOLF & A. K. ABBAS. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152: 2172-2179.
18. WALL, D. A., S. D. HAMBERG, S. J. BURAKOFF, D. S. REYNOLDS, A. K. ABBAS & L. M. FERRARA. 1988. Immunodeficiency in garft-versus-host disease. I. Mechanism of immune suppression. J. Immunol. 140: 2970-2976.
19. HUCHET, R., M. BRULEY-ROSSET, C. MATHIOT, D. GRANDJON & O. HALLE-PANNENKO. 1993. Involvement of IFN-gamma and transforming growth factor-β in graft-vs-host reaction-associated immunosuppression. J. Immunol. 150: 2517-2524.
20. ISHIKURA, H., S. JAYARAMAN, V. KUCHROO, B. DIAMOND, S. SAITO & M. E. DORF. 1989. Functional analysis of cloned macrophage hybridomas. J. Immunol. 143: 414-419.
21. NOMA, T. & M. E. DORF. 1985. Modulation of suppressor T cell induction with γ-interferon. J. Immunol. 135: 3655-3660.
22. GOSSELIN, D., R. TURCOTTE & S. LEMIEUX. 1995. Cellular target of in vitro-induced suppressor cells derived from the spleen of Mycobacterium lepraemurium-infected mice and role of IFN-γ in their development. J. Leukocyte Biol. 57: 122-128.
23. TOMIOKA, H., K. SATO, W. W. MAW & H. SAITO. 1995. The role of tumor necrosis factor, interferon-γ, transforming growth factor β, and nitric oxide in the expression of immunosuppressive functions of splenic macrophages induced by Mycobacterium avium complex infection. J. Leukocyte Biol. 58: 704-712.
24. SILEGHEM, M., R. HAMERS & P. DE BAETSELIER. 1987. Experimental Trypanosoma brucei infections selectively suppress both interleukin 2 production and interleukin 2 receptor expression. Eur. J. Immunol. 17: 1417-1421.
25. DARJI, A., M. SILEGHEM, H. HEREMANS, L. BRYS, A. BILLIAU & P. DE BAETSELIER. 1993. Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: Active participation of endogenous gamma interferon. Infect. Immun. 61: 3098-3102.
26. METZGER, Z., J. T. HOFFELD & J. J. OPPENHEIM. 1980. Macrophage-mediated suppression. I. Evidence for participation of both hydrogen peroxide and prostaglandin in suppression of murine lymphocyte proliferation. J. Immunol. 124: 983-988.
27. BORASCHI, D., S. CENSINI & A. TAGLIABUE. 1984. Interferon-γ reduces macrophage-suppressive activity by inhibiting prostaglandin E2 release and inducing interleukin 1 production. J. Immunol. 133: 764-768.
28. ALBINA, J. E., J. A. ABATE & W. L. J. HENRY. 1991. Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-γ in the induction of nitric oxide-synthesizing pathway. J. Immunol. 147: 144-148.
29. MILLS, C. D. 1991. Molecular basis of suppressor macrophages. Arginine metabolism via the nitric oxide synthetase pathway. J. Immunol. 146: 2719-2723.
30. TWARDZIK, D. R., J. A. MIKOVITS, J. E. RANCHALIS, A. F. PURCHIO, L. ELLINGSWORTH & F. W. RUSCETTI. 1990. γ-Interferon-induced activation of latent transforming growth-factor-β by human monocytes. Ann. N.Y. Acad. Sci. 593: 276-284.
31. ZAMVIL, S. S. & L. STEINMAN. 1990. The T lymphocyte in experimental allergic encephalomyelitis. Ann. Rev. Immunol. 8: 579-621.
32. KENNEDY, M. K., D. S. TORRANCE, K. S. PICHA & K. M. MOHLER. 1992. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149: 2496-2505.
33. KHOURY, S. J., W. W. HANCOCK & H. L. WEINER. 1992. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 176: 1355-1364.
34. MERRILL, J. E., D. H. KONO, J. CLAYTON, D. G. ANDO, D. R. HINTON & F. M. HOFMAN. 1992. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL/J and B10.PL mice. Proc. Natl. Acad. Sci. USA 89: 574-578.
35. RENNO, T., J.-Y. LIN, C. PICCIRILLO, J. ANTEL & T. OWENS. 1994. Cytokine production by cells in cerebrospinal fluid during Experimental Allergic Encephalomyelitis in SJL/J mice. J. Neuroimmunol. 49: 1-7.
36. MUSTAFA, M., P. DIENER, B. HŌJEBERG, P. VAN DER MEIDE & T. OLSSON. 1991. T cell immunity and interferon-γ secretion during experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 31: 165-177.
37. MCDONALD, A. H. & R. H. SWANBORG. 1988. Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis. J. Immunol. 140: 1132-1138.
38. VASS, K., K. HEININGER, B. SCHĀFER, C. LININGTON & H. LASSMAN. 1992. Interferon-γ potentiates antibody-mediated demyelination in vivo. Ann. Neurol. 32: 198-206.
39. BILLIAU, A., H. HEREMANS, F. VANDEKERCKHOVE, R. DIJKMANS, H. SOBIS, E. MEULEPAS & H. CARTON. 1988. Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma. J. Immunol. 140: 1506-1510.
40. DUONG, T. T., J. ST LOUIS, J. J. GILBERT, F. D. FINKELMAN & G. H. STREJAN. 1992. Effect of anti-interferon-γ and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse. J. Neuroimmunol. 36: 105-115.
41. CASPI, R. R., C.-C. CHAN, B. G. GRUBBS, P. B. SILVER, B. WIGGERT, C. F. PARSA, S. BAHMANYAR, A. BILLIAU & H. HEREMANS. 1994. Endogenous systemic IFN-gamma has a protective role against ocular autoimmunity in mice. J. Immunol. 152: 890-899.
42. VOORTHUIS, J. A. C., B. M. J. UITDEHAAG, C. J. A. DE GROOT, P. H. GOEDE, P. H. VAN DER MEIDE & C. D. DIJKSTRA. 1990. Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in rats. Clin. Exp. Immunol. 81: 183-188.
43. DUONG, T. T., F. D. FINKELMAN, B. SINGH & G. H. STREJAN. 1994. Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains. J. Neuroimmunol. 53: 101-107.
44. HEREMANS, H., C. DILLEN, M. GROENEN, E. MARTENS & A. BILLIAU. 1996. Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: Enhancement by monoclonal antibodies against IFN-γ. Eur. J. Immunol. 26: 2393-2398.
45. LEONARD, J. P., K. E. WALDBURGER & S. J. GOLDMAN. 1996. Regulation of experimental autoimmune encephalomyelitis by interleukin-12. Ann. N.Y. Acad. Sci. 795: 216-226.
46. MAURITZ, N. J., R. HOLMDAHL, R. JONSSON, P. H. VAN DER MEIDE, A. SCHEYNIUS & L. KLARESKOG. 1988. Treatment with gamma-interferon triggers the onset of collagen arthritis in mice. Arthritis Rheum. 31: 1297-1304.
47. NAKAJIMA, H., H. TAKAMORI, Y. HIYAMA & W. TSUKUDA. 1990. The effect of treatment with interferon-gamma on type II collagen-induced arthritis. Clin. Exp. Immunol. 81: 441-445.
48. WILLIAMS, R. O., D. G. WILLIAMS, M. FELDMANN & R. N. MAINI. 1993. Increased limb involvement in murine collagen-induced artritis following treatment with anti-interferon-gamma. Clin. Exp. Immunol. 92: 323-327.
49. BOISSIER, M.-C., G. CHIOCCHIA, N. BESSIS, J. HAJNAL, G. GAROTTA, F. NICOLETTI & C. FOURNIER. 1995. Biphasic effect of interferon-gamma in murine collagen-induced arthritis. Eur. J. Immunol. 25: 1184-1190.
50. VERMEIRE, K., H. HEREMANS, M. VANDEPUTTE, J. HUANG, A. BILLIAU & P. MATTHYS. 1997. Accelerated collagen-induced arthritis in interferon-γ receptor-deficient mice. J. Immunol. 158: 5507-5513.