-
1
-
-
3042806973
-
BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas
-
10.1007/s00428-004-1018-0, 15095090
-
Soares P, Trovisco V, Rocha AS, Feijao T, Rebocho AP, Fonseca E, Vieira de Castro I, Cameselle-Teijeiro J, Cardoso-Oliveira M, Sobrinho-Simoes M. BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas. Virchows Arch 2004, 444:572-576. 10.1007/s00428-004-1018-0, 15095090.
-
(2004)
Virchows Arch
, vol.444
, pp. 572-576
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
Feijao, T.4
Rebocho, A.P.5
Fonseca, E.6
Vieira de Castro, I.7
Cameselle-Teijeiro, J.8
Cardoso-Oliveira, M.9
Sobrinho-Simoes, M.10
-
2
-
-
10744222003
-
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas
-
10.1210/jc.2003-030838, 14602780
-
Nikiforova MN, Kimura ET, Gandhi M, Biddinger PW, Knauf JA, Basolo F, Zhu Z, Giannini R, Salvatore G, Fusco A. BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab 2003, 88:5399-5404. 10.1210/jc.2003-030838, 14602780.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5399-5404
-
-
Nikiforova, M.N.1
Kimura, E.T.2
Gandhi, M.3
Biddinger, P.W.4
Knauf, J.A.5
Basolo, F.6
Zhu, Z.7
Giannini, R.8
Salvatore, G.9
Fusco, A.10
-
3
-
-
0043170833
-
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC
-
10.1038/sj.onc.1206706, 12881714
-
Soares P, Trovisco V, Rocha AS, Lima J, Castro P, Preto A, Maximo V, Botelho T, Seruca R, Sobrinho-Simoes M. BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene 2003, 22:4578-4580. 10.1038/sj.onc.1206706, 12881714.
-
(2003)
Oncogene
, vol.22
, pp. 4578-4580
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
Lima, J.4
Castro, P.5
Preto, A.6
Maximo, V.7
Botelho, T.8
Seruca, R.9
Sobrinho-Simoes, M.10
-
4
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
10.1038/nature00766, 12068308
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W. Mutations of the BRAF gene in human cancer. Nature 2002, 417:949-954. 10.1038/nature00766, 12068308.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
-
5
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer KE, Pritchard CA. Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 2003, 1653:25-40.
-
(2003)
Biochim Biophys Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
6
-
-
19644397029
-
Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling
-
10.1038/sj.onc.1208544, 15735667
-
Bhatt KV, Spofford LS, Aram G, McMullen M, Pumiglia K, Aplin AE. Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling. Oncogene 2005, 24:3459-3471. 10.1038/sj.onc.1208544, 15735667.
-
(2005)
Oncogene
, vol.24
, pp. 3459-3471
-
-
Bhatt, K.V.1
Spofford, L.S.2
Aram, G.3
McMullen, M.4
Pumiglia, K.5
Aplin, A.E.6
-
7
-
-
33847027884
-
Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells
-
10.1038/sj.onc.1209861, 16924241
-
Bhatt KV, Hu R, Spofford LS, Aplin AE. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells. Oncogene 2007, 26:1056-1066. 10.1038/sj.onc.1209861, 16924241.
-
(2007)
Oncogene
, vol.26
, pp. 1056-1066
-
-
Bhatt, K.V.1
Hu, R.2
Spofford, L.S.3
Aplin, A.E.4
-
8
-
-
0141816881
-
Suppression of BRAF(V599E) in human melanoma abrogates transformation
-
Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA. Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer Res 2003, 63:5198-5202.
-
(2003)
Cancer Res
, vol.63
, pp. 5198-5202
-
-
Hingorani, S.R.1
Jacobetz, M.A.2
Robertson, G.P.3
Herlyn, M.4
Tuveson, D.A.5
-
9
-
-
0142211228
-
Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway
-
10.1074/jbc.M308709200, 12917419
-
Calipel A, Lefevre G, Pouponnot C, Mouriaux F, Eychene A, Mascarelli F. Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway. J Biol Chem 2003, 278:42409-42418. 10.1074/jbc.M308709200, 12917419.
-
(2003)
J Biol Chem
, vol.278
, pp. 42409-42418
-
-
Calipel, A.1
Lefevre, G.2
Pouponnot, C.3
Mouriaux, F.4
Eychene, A.5
Mascarelli, F.6
-
10
-
-
4444240325
-
Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference
-
10.1038/sj.onc.1207812, 15208655
-
Sumimoto H, Miyagishi M, Miyoshi H, Yamagata S, Shimizu A, Taira K, Kawakami Y. Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference. Oncogene 2004, 23:6031-6039. 10.1038/sj.onc.1207812, 15208655.
-
(2004)
Oncogene
, vol.23
, pp. 6031-6039
-
-
Sumimoto, H.1
Miyagishi, M.2
Miyoshi, H.3
Yamagata, S.4
Shimizu, A.5
Taira, K.6
Kawakami, Y.7
-
11
-
-
4344584872
-
B-RAF is a therapeutic target in melanoma
-
10.1038/sj.onc.1207785, 15208680
-
Karasarides M, Chiloeches A, Hayward R, Niculescu-Duvaz D, Scanlon I, Friedlos F, Ogilvie L, Hedley D, Martin J, Marshall CJ. B-RAF is a therapeutic target in melanoma. Oncogene 2004, 23:6292-6298. 10.1038/sj.onc.1207785, 15208680.
-
(2004)
Oncogene
, vol.23
, pp. 6292-6298
-
-
Karasarides, M.1
Chiloeches, A.2
Hayward, R.3
Niculescu-Duvaz, D.4
Scanlon, I.5
Friedlos, F.6
Ogilvie, L.7
Hedley, D.8
Martin, J.9
Marshall, C.J.10
-
12
-
-
30544434479
-
Growth factors rescue cutaneous melanoma cells from apoptosis induced by knockdown of mutated (V 600 E) B-RAF
-
10.1038/sj.onc.1208758, 16007203
-
Christensen C, Guldberg P. Growth factors rescue cutaneous melanoma cells from apoptosis induced by knockdown of mutated (V 600 E) B-RAF. Oncogene 2005, 24:6292-6302. 10.1038/sj.onc.1208758, 16007203.
-
(2005)
Oncogene
, vol.24
, pp. 6292-6302
-
-
Christensen, C.1
Guldberg, P.2
-
13
-
-
31544442670
-
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models
-
10.1158/0008-5472.CAN-05-2720, 16424035
-
Hoeflich KP, Gray DC, Eby MT, Tien JY, Wong L, Bower J, Gogineni A, Zha J, Cole MJ, Stern HM. Oncogenic BRAF is required for tumor growth and maintenance in melanoma models. Cancer Res 2006, 66:999-1006. 10.1158/0008-5472.CAN-05-2720, 16424035.
-
(2006)
Cancer Res
, vol.66
, pp. 999-1006
-
-
Hoeflich, K.P.1
Gray, D.C.2
Eby, M.T.3
Tien, J.Y.4
Wong, L.5
Bower, J.6
Gogineni, A.7
Zha, J.8
Cole, M.J.9
Stern, H.M.10
-
14
-
-
38949208776
-
BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations
-
10.1002/path.2295, 18098337
-
Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. J Pathol 2008, 214:320-327. 10.1002/path.2295, 18098337.
-
(2008)
J Pathol
, vol.214
, pp. 320-327
-
-
Preto, A.1
Figueiredo, J.2
Velho, S.3
Ribeiro, A.S.4
Soares, P.5
Oliveira, C.6
Seruca, R.7
-
15
-
-
34250704834
-
Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice
-
10.1158/1535-7163.MCT-06-0595, 17575107
-
Kim S, Yazici YD, Calzada G, Wang ZY, Younes MN, Jasser SA, El-Naggar AK, Myers JN. Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. Mol Cancer Ther 2007, 6:1785-1792. 10.1158/1535-7163.MCT-06-0595, 17575107.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1785-1792
-
-
Kim, S.1
Yazici, Y.D.2
Calzada, G.3
Wang, Z.Y.4
Younes, M.N.5
Jasser, S.A.6
El-Naggar, A.K.7
Myers, J.N.8
-
16
-
-
34347208361
-
BRAF V600E Maintains Proliferation, Transformation and Tumorigenicity of BRAF-Mutant Papillary Thyroid Cancer Cells
-
10.1210/jc.2006-1613, 17374713
-
Liu D, Liu Z, Condouris S, Xing M. BRAF V600E Maintains Proliferation, Transformation and Tumorigenicity of BRAF-Mutant Papillary Thyroid Cancer Cells. J Clin Endocrinol Metab 2007, 92:2264-2271. 10.1210/jc.2006-1613, 17374713.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2264-2271
-
-
Liu, D.1
Liu, Z.2
Condouris, S.3
Xing, M.4
-
17
-
-
33645069923
-
BRAF is a therapeutic target in aggressive thyroid carcinoma
-
10.1158/1078-0432.CCR-05-2378, 16533790
-
Salvatore G, De Falco V, Salerno P, Nappi TC, Pepe S, Troncone G, Carlomagno F, Melillo RM, Wilhelm SM, Santoro M. BRAF is a therapeutic target in aggressive thyroid carcinoma. Clin Cancer Res 2006, 12:1623-1629. 10.1158/1078-0432.CCR-05-2378, 16533790.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1623-1629
-
-
Salvatore, G.1
De Falco, V.2
Salerno, P.3
Nappi, T.C.4
Pepe, S.5
Troncone, G.6
Carlomagno, F.7
Melillo, R.M.8
Wilhelm, S.M.9
Santoro, M.10
-
18
-
-
34147144679
-
Targeting BRAFV600E in thyroid carcinoma: therapeutic implications
-
10.1158/1535-7163.MCT-06-0449, 17363500
-
Mitsiades CS, Negri J, McMullan C, McMillin DW, Sozopoulos E, Fanourakis G, Voutsinas G, Tseleni-Balafouta S, Poulaki V, Batt D, Mitsiades N. Targeting BRAFV600E in thyroid carcinoma: therapeutic implications. Mol Cancer Ther 2007, 6:1070-1078. 10.1158/1535-7163.MCT-06-0449, 17363500.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1070-1078
-
-
Mitsiades, C.S.1
Negri, J.2
McMullan, C.3
McMillin, D.W.4
Sozopoulos, E.5
Fanourakis, G.6
Voutsinas, G.7
Tseleni-Balafouta, S.8
Poulaki, V.9
Batt, D.10
Mitsiades, N.11
-
19
-
-
33645698808
-
Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
-
10.1158/1078-0432.CCR-05-1729, 16551863
-
Ouyang B, Knauf JA, Smith EP, Zhang L, Ramsey T, Yusuff N, Batt D, Fagin JA. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo. Clin Cancer Res 2006, 12:1785-1793. 10.1158/1078-0432.CCR-05-1729, 16551863.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1785-1793
-
-
Ouyang, B.1
Knauf, J.A.2
Smith, E.P.3
Zhang, L.4
Ramsey, T.5
Yusuff, N.6
Batt, D.7
Fagin, J.A.8
-
20
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
10.1016/S0092-8674(04)00215-6, 15035987
-
Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004, 116:855-867. 10.1016/S0092-8674(04)00215-6, 15035987.
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
Lee, S.4
Niculescu-Duvaz, D.5
Good, V.M.6
Jones, C.M.7
Marshall, C.J.8
Springer, C.J.9
Barford, D.10
Marais, R.11
-
21
-
-
36649017735
-
Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines
-
10.1089/thy.2007.0097, 17725429
-
Meireles AM, Preto A, Rocha AS, Rebocho AP, Maximo V, Pereira-Castro I, Moreira S, Feijao T, Botelho T, Marques R. Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid 2007, 17:707-715. 10.1089/thy.2007.0097, 17725429.
-
(2007)
Thyroid
, vol.17
, pp. 707-715
-
-
Meireles, A.M.1
Preto, A.2
Rocha, A.S.3
Rebocho, A.P.4
Maximo, V.5
Pereira-Castro, I.6
Moreira, S.7
Feijao, T.8
Botelho, T.9
Marques, R.10
-
22
-
-
57349103343
-
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification
-
2582569, 18713817, 10.1210/jc.2008-1102
-
Schweppe RE, Klopper JP, Korch C, Pugazhenthi U, Benezra M, Knauf JA, Fagin JA, Marlow LA, Copland JA, Smallridge RC, Haugen BR. Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. J Clin Endocrinol Metab 2008, 93:4331-4341. 2582569, 18713817, 10.1210/jc.2008-1102.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4331-4341
-
-
Schweppe, R.E.1
Klopper, J.P.2
Korch, C.3
Pugazhenthi, U.4
Benezra, M.5
Knauf, J.A.6
Fagin, J.A.7
Marlow, L.A.8
Copland, J.A.9
Smallridge, R.C.10
Haugen, B.R.11
-
23
-
-
0034784725
-
Discovery of a novel Raf kinase inhibitor
-
10.1677/erc.0.0080219, 11566613
-
Lyons JF, Wilhelm S, Hibner B, Bollag G. Discovery of a novel Raf kinase inhibitor. Endocr Relat Cancer 2001, 8:219-225. 10.1677/erc.0.0080219, 11566613.
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 219-225
-
-
Lyons, J.F.1
Wilhelm, S.2
Hibner, B.3
Bollag, G.4
-
24
-
-
33749238553
-
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
-
10.1038/nrd2130, 17016424
-
Wilhelm S, Carter C, Lynch M, Lowinger T, Dumas J, Smith RA, Schwartz B, Simantov R, Kelley S. Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 2006, 5:835-844. 10.1038/nrd2130, 17016424.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
Lowinger, T.4
Dumas, J.5
Smith, R.A.6
Schwartz, B.7
Simantov, R.8
Kelley, S.9
-
25
-
-
33846227109
-
Targeting BRAF in thyroid cancer
-
2360215, 17179987, 10.1038/sj.bjc.6603520
-
Espinosa AV, Porchia L, Ringel MD. Targeting BRAF in thyroid cancer. Br J Cancer 2007, 96:16-20. 2360215, 17179987, 10.1038/sj.bjc.6603520.
-
(2007)
Br J Cancer
, vol.96
, pp. 16-20
-
-
Espinosa, A.V.1
Porchia, L.2
Ringel, M.D.3
-
26
-
-
0346057796
-
BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency
-
10.1038/sj.onc.1207061, 14668801
-
Oliveira C, Pinto M, Duval A, Brennetot C, Domingo E, Espin E, Armengol M, Yamamoto H, Hamelin R, Seruca R, Schwartz S. BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency. Oncogene 2003, 22:9192-9196. 10.1038/sj.onc.1207061, 14668801.
-
(2003)
Oncogene
, vol.22
, pp. 9192-9196
-
-
Oliveira, C.1
Pinto, M.2
Duval, A.3
Brennetot, C.4
Domingo, E.5
Espin, E.6
Armengol, M.7
Yamamoto, H.8
Hamelin, R.9
Seruca, R.10
Schwartz, S.11
-
27
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
10.1038/sj.onc.1210392, 17496909
-
Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene 2007, 26:3100-3112. 10.1038/sj.onc.1210392, 17496909.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
28
-
-
33947594129
-
Hyperactive Ras in developmental disorders and cancer
-
10.1038/nrc2109, 17384584
-
Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007, 7:295-308. 10.1038/nrc2109, 17384584.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 295-308
-
-
Schubbert, S.1
Shannon, K.2
Bollag, G.3
-
29
-
-
30944445020
-
BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis
-
10.1210/en.2005-0280, 16254036
-
Mitsutake N, Miyagishi M, Mitsutake S, Akeno N, Mesa C, Knauf JA, Zhang L, Taira K, Fagin JA. BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis. Endocrinology 2006, 147:1014-1019. 10.1210/en.2005-0280, 16254036.
-
(2006)
Endocrinology
, vol.147
, pp. 1014-1019
-
-
Mitsutake, N.1
Miyagishi, M.2
Mitsutake, S.3
Akeno, N.4
Mesa, C.5
Knauf, J.A.6
Zhang, L.7
Taira, K.8
Fagin, J.A.9
-
30
-
-
58149306363
-
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation
-
2575166, 18799615, 10.1091/mbc.E08-06-0617
-
Rocha AS, Paternot S, Coulonval K, Dumont JE, Soares P, Roger PP. Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation. Mol Biol Cell 2008, 19:4814-4825. 2575166, 18799615, 10.1091/mbc.E08-06-0617.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4814-4825
-
-
Rocha, A.S.1
Paternot, S.2
Coulonval, K.3
Dumont, J.E.4
Soares, P.5
Roger, P.P.6
-
31
-
-
33644747449
-
BAY 43-9006 inhibition of oncogenic RET mutants
-
Carlomagno F, Anaganti S, Guida T, Salvatore G, Troncone G, Wilhelm SM, Santoro M. BAY 43-9006 inhibition of oncogenic RET mutants. J Natl Cancer Inst 2006, 98:326-334.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 326-334
-
-
Carlomagno, F.1
Anaganti, S.2
Guida, T.3
Salvatore, G.4
Troncone, G.5
Wilhelm, S.M.6
Santoro, M.7
-
32
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
10.1158/0008-5472.CAN-04-1443, 15466206
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004, 64:7099-7109. 10.1158/0008-5472.CAN-04-1443, 15466206.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
-
33
-
-
33847027884
-
Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27(Kip1) in human melanoma cells
-
10.1038/sj.onc.1209861, 16924241
-
Bhatt KV, Hu R, Spofford LS, Aplin AE. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27(Kip1) in human melanoma cells. Oncogene 2006, 26:1056-1066. 10.1038/sj.onc.1209861, 16924241.
-
(2006)
Oncogene
, vol.26
, pp. 1056-1066
-
-
Bhatt, K.V.1
Hu, R.2
Spofford, L.S.3
Aplin, A.E.4
-
34
-
-
0033941559
-
Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells
-
86042, 10891505, 10.1128/MCB.20.15.5690-5699.2000
-
Jones CJ, Kipling D, Morris M, Hepburn P, Skinner J, Bounacer A, Wyllie FS, Ivan M, Bartek J, Wynford-Thomas D, Bond JA. Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells. Mol Cell Biol 2000, 20:5690-5699. 86042, 10891505, 10.1128/MCB.20.15.5690-5699.2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5690-5699
-
-
Jones, C.J.1
Kipling, D.2
Morris, M.3
Hepburn, P.4
Skinner, J.5
Bounacer, A.6
Wyllie, F.S.7
Ivan, M.8
Bartek, J.9
Wynford-Thomas, D.10
Bond, J.A.11
-
35
-
-
32944479041
-
The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells
-
10.1158/0008-5472.CAN-05-0808, 16452220
-
Panka DJ, Wang W, Atkins MB, Mier JW. The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells. Cancer Res 2006, 66:1611-1619. 10.1158/0008-5472.CAN-05-0808, 16452220.
-
(2006)
Cancer Res
, vol.66
, pp. 1611-1619
-
-
Panka, D.J.1
Wang, W.2
Atkins, M.B.3
Mier, J.W.4
-
36
-
-
27144502652
-
The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006
-
10.1038/sj.onc.1208841, 16007148
-
Yu C, Bruzek LM, Meng XW, Gores GJ, Carter CA, Kaufmann SH, Adjei AA. The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. Oncogene 2005, 24:6861-6869. 10.1038/sj.onc.1208841, 16007148.
-
(2005)
Oncogene
, vol.24
, pp. 6861-6869
-
-
Yu, C.1
Bruzek, L.M.2
Meng, X.W.3
Gores, G.J.4
Carter, C.A.5
Kaufmann, S.H.6
Adjei, A.A.7
-
37
-
-
50649095250
-
Phase II trial of sorafenib in advanced thyroid cancer
-
2653134, 18541894, 10.1200/JCO.2008.16.3279
-
Gupta-Abramson V, Troxel AB, Nellore A, Puttaswamy K, Redlinger M, Ransone K, Mandel SJ, Flaherty KT, Loevner LA, O'Dwyer PJ, Brose MS. Phase II trial of sorafenib in advanced thyroid cancer. J Clin Oncol 2008, 26:4714-4719. 2653134, 18541894, 10.1200/JCO.2008.16.3279.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4714-4719
-
-
Gupta-Abramson, V.1
Troxel, A.B.2
Nellore, A.3
Puttaswamy, K.4
Redlinger, M.5
Ransone, K.6
Mandel, S.J.7
Flaherty, K.T.8
Loevner, L.A.9
O'Dwyer, P.J.10
Brose, M.S.11
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