A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32835-32846

  Fishman Jacob, Tali ^a   Reznichenko, Lydia ^a   Youdim, Moussa B H ^a   Mandel, Silvia A ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

1-METHYL-4-PHENYLPYRIDINIUM; AGGRESOMES; CELL CYCLE; CELL LINES; CELLULAR LEVELS; DOPAMINE TRANSPORTERS; E3 LIGASE; HEAT-SHOCK; IMMUNOREACTIVITIES; LIGASE COMPLEX; NEURODEGENERATION; NEURONAL DAMAGE; NEURONAL FUNCTION; NEW MODEL; PARKINSON DISEASE; PROTEASOMES; S-PHASE; SERUM STARVATION; SHORT HAIRPIN RNA; SUBSTANTIA NIGRA; SYNUCLEIN; TYROSINE HYDROXYLASE; UBIQUITIN; WILD TYPES;

AMINO ACIDS; BRAIN; CELL CULTURE; ENZYMES; GENE ENCODING; NUCLEIC ACIDS; RNA;

PROTEINS;

1 METHYL 4 PHENYLPYRIDINIUM; ALPHA SYNUCLEIN; CULLIN; DOPAMINE TRANSPORTER; F BOX PROTEIN; GAMMA TUBULIN; HEAT SHOCK COGNATE PROTEIN 70; NEUROTOXIN; PROTEASOME; S PHASE KINASE ASSOCIATED PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 1A; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TYROSINE 3 MONOOXYGENASE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2;

AGGRESOME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE SILENCING; IMMUNOREACTIVITY; LENTIVIRINAE; MOUSE; NERVE CELL LESION; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA;

ANIMALS; CELL LINE; CELL SURVIVAL; GENE SILENCING; HSC70 HEAT-SHOCK PROTEINS; MALE; MICE; MICE, INBRED C57BL; NEURODEGENERATIVE DISEASES; NEURONS; NEUROTOXINS; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

MURINAE;

EID: 70450280570     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.034223     Document Type: Article

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