Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit

Journal of Neuroscience

Volumn 27, Issue 19, 2007, Pages 5163-5171

  Nelson, Rick F ^a,b   Glenn, Kevin A ^b   Zhang, Yuzhou ^b   Wen, Hsiang ^b   Knutson, Tina ^b   Gouvion, Cynthia M ^b   Robinson, Barbara K ^b   Zhou, Zouping ^b   Yang, Baoli ^b   Smith, Richard J H ^b   Paulson, Henry L ^b  

^a The University of Iowa   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Deafness; Degradation; Fbx2; Glycoprotein; Skp1; Ubiquitin

Indexed keywords

CONNEXIN 26; F BOX PROTEIN; GAP JUNCTION PROTEIN; GLYCOPROTEIN; ORGAN OF CORTI PROTEIN 1; PROTEIN FBX2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY RESPONSE; CELL DEGENERATION; COCHLEA; COMPLEX FORMATION; CONTROLLED STUDY; CORTI ORGAN; HAIR CELL; HEARING IMPAIRMENT; HEARING LOSS; IMMUNOFLUORESCENCE; INNER EAR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN QUALITY; SPIRAL GANGLION; WESTERN BLOTTING;

AGING; ANIMALS; CELL MEMBRANE; COCHLEAR DISEASES; CONNEXINS; DEAFNESS; F-BOX PROTEINS; GLYCOPROTEINS; HAIR CELLS; HEARING LOSS, SENSORINEURAL; LABYRINTH SUPPORTING CELLS; MACROMOLECULAR SUBSTANCES; MICE; MICE, KNOCKOUT; NERVE DEGENERATION; PROTEIN BINDING; PROTEIN SUBUNITS; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

EID: 34248359919     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0206-07.2007     Document Type: Article

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