Peripheral benzodiazepine receptor ligands: Mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells

Biochemical Pharmacology

Volumn 68, Issue 1, 2004, Pages 125-134

  Chelli, Beatrice ^a   Lena, Annalisa ^a   Vanacore, Renato ^b   Da Pozzo, Eleonora ^a   Costa, Barbara ^a   Rossi, Leonardo ^a   Salvetti, Alessandra ^a   Scatena, Fabrizio ^b   Ceruti, Stefania ^c   Abbracchio, Maria P ^c   Gremigni, Vittorio ^a   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b CISANELLO HOSPITAL   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

m; mitochondrial permeability transition; mitochondrial transmembrane potential; MPT; MTS; PBR; peripheral benzodiazepine receptor; TEM; transmission electron microscopy

Indexed keywords

4' CHLORODIAZEPAM; BENZODIAZEPINE RECEPTOR; CLONAZEPAM; DIAZEPAM; DNA FRAGMENT; LIGAND; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; RO 54864;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FLOW CYTOMETRY; GLIOMA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZODIAZEPINONES; CASPASE 3; CASPASES; GLIOMA; ISOQUINOLINES; LIGANDS; MEMBRANE POTENTIALS; MITOCHONDRIA; RATS; RECEPTORS, GABA-A; TUMOR CELLS, CULTURED;

EID: 2942622303     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.03.008     Document Type: Article

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