Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32264-32271

  Sagana, Rommel L ^a   Yan, Mei ^a   Cornett, Ashley M ^a   Tsui, Jessica L ^a   Stephenson, David A ^a   Huang, Steven S ^a   Moore, Bethany B ^a   Ballinger, Megan N ^a   Melonakos, Janet ^b   Kontos, Christopher D ^b   Aronoff, David M ^a   Peters Golden, Marc ^a   White, Eric S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC EFFECT; ARACHIDONIC ACIDS; CELLULAR EFFECTS; DOWN-REGULATION; FIBROBLAST RESPONSE; GENE TRANSCRIPTIONS; INHIBITORY EFFECT; PHOSPHATASE AND TENSIN HOMOLOGUES; POSITIVE FEEDBACK LOOP; PROSTAGLANDINE; PROTEIN COUPLED RECEPTORS; RECEPTOR BINDING; RECEPTOR EXPRESSION; SMOOTH MUSCLE ACTINS; TRANSFORMING GROWTH FACTORS;

CHROMOSOMES; ENZYME INHIBITION; FEEDBACK; FETAL MONITORING; FIBROBLASTS; RESTORATION; SIGNALING; TISSUE; TRANSCRIPTION;

CELL CULTURE;

ALPHA SMOOTH MUSCLE ACTIN; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTAGLANDIN E2;

ANIMAL CELL; ANTIFIBROTIC ACTIVITY; ARTICLE; CELL ACTIVATION; CHROMOSOME 10; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; REGULATORY MECHANISM; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; COLLAGEN; CYCLIC AMP; DINOPROSTONE; DOWN-REGULATION; FIBROBLASTS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH; PTEN PHOSPHOHYDROLASE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PROSTAGLANDIN E;

EID: 70450240788     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.004796     Document Type: Article

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