Quantification of lipid droplets and associated proteins in cellular models of obesity via high-content/high-throughput microscopy and automated image analysis

Assay and Drug Development Technologies

Volumn 7, Issue 5, 2009, Pages 440-460

  McDonough, Patrick M ^a   Agustin, Ramses M ^b   Ingermanson, Randall S ^a   Loy, Patricia A ^a   Buehrer, Benjamin M ^c   Nicoll, James B ^c   Prigozhina, Natalie L ^b   Mikic, Ivana ^b   Price, Jeffrey H ^a,b  

^a VALA SCIENCES INC   (United States)

^b BURNHAM INSTITUTE   (United States)

^c Zen Bio Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAT DROPLET; HORMONE SENSITIVE LIPASE; OLEIC ACID; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEIN KINASE C; PSEUDOEPHEDRINE PLUS TRIPROLIDINE; ROSIGLITAZONE;

ADIPOGENESIS; ALGORITHM; ANIMAL CELL; ARTICLE; AUTOANALYSIS; BIOLOGICAL MODEL; CELL LABELING; CONTROLLED STUDY; CORRELATION COEFFICIENT; CYTOMETRY; FEMALE; HELA CELL; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LIVER CELL; MACROPHAGE; MICROSCOPY; NONHUMAN; OBESITY; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ADIPOCYTES; ALGORITHMS; CELL LINE; DATA INTERPRETATION, STATISTICAL; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; FLOW CYTOMETRY; HEPATOCYTES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIPIDS; LIPOPROTEINS; MICROSCOPY; MODELS, BIOLOGICAL; OBESITY; PROTEINS; TERMINOLOGY AS TOPIC; TRIGLYCERIDES;

EID: 70450228663     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0196     Document Type: Article

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