Statistics of assay validation in high throughput cell imaging of nuclear factor κB nuclear translocation

Assay and Drug Development Technologies

Volumn 3, Issue 5, 2005, Pages 483-499

  Morelock, Maurice M ^a   Hunter, Edward A ^b,h   Moran, Timothy J ^c,h   Heynen, Susanne ^c,h   Laris, Casey ^c,h   Thieleking, Michael ^c,h   Akong, Michael ^d   Mikic, Ivana ^b,h   Callaway, Scott ^b,h   DeLeon, Rodney P ^a   Goodacre, Angela ^e,h   Zacharias, David ^f   Price, Jeffrey H ^b,c,g,h  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b VALA SCIENCES INC   (United States)

^c BECKMAN COULTER INC   (United States)

^d Neuro Acupuncture Associates   (United States)

^e Olympus America Inc   (United States)

^f UNIVERSITY OF FLORIDA   (United States)

^g BURNHAM INSTITUTE   (United States)

^h Q3DM Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA;

ARTICLE; CELL ASSAY; CELL COUNT; CONCENTRATION RESPONSE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CULTURE MEDIUM; HELA CELL; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; IMAGE ANALYSIS; INHIBITION KINETICS; MATHEMATICAL COMPUTING; METHODOLOGY; MONTE CARLO METHOD; PROTEIN TRANSPORT; STATISTICAL MODEL; STATISTICS; VALIDATION PROCESS;

ACTIVE TRANSPORT, CELL NUCLEUS; ALGORITHMS; BIOLOGICAL ASSAY; CELL COUNT; CELL NUCLEUS; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HELA CELLS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; PROTEIN TRANSPORT; RECEPTORS, INTERLEUKIN-1; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SIALOGLYCOPROTEINS; SOFTWARE; SOFTWARE VALIDATION;

EID: 29244453207     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2005.3.483     Document Type: Article

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