Metabolic adaptations in the absence of perilipin: Increased β-oxidation and decreased hepatic glucose production associated with peripheral insulin resistance but normal glucose tolerance in perilipin-null mice

Journal of Biological Chemistry

Volumn 279, Issue 34, 2004, Pages 35150-35158

  Saha, Pradip K ^a   Kojima, Hideto ^a,b   Martinez Botas, Javier ^a,c   Sunehag, Agneta L ^a   Chan, Lawrence ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACIDS; GLYCEROL; INSULIN; LIVING SYSTEMS STUDIES; METABOLISM; MUSCLE; OXIDATION; PROTEINS; TISSUE;

LIPOLYSIS; PLASMA GLUCOSE;

GLUCOSE;

FATTY ACID; GLUCOSE; GLYCEROL; INSULIN; LIPOPROTEIN; PERILIPIN; TRACER; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ADAPTATION; ADIPOSE TISSUE; ADOLESCENT; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME REGULATION; FATTY ACID OXIDATION; GLUCOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPOLYSIS; LIVER METABOLISM; MOUSE; MUSCLE METABOLISM; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; WHITE ADIPOSE TISSUE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; FATTY ACIDS; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; LIPOLYSIS; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PHOSPHOPROTEINS;

ANIMALIA;

EID: 4143094816     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405499200     Document Type: Article

References (44)

1. Barsh, G. S., Farooqi, I. S., and O'Rahilly, S. (2000) Nature 404, 644-651
2. Martinez-Botas, J., Anderson, J. B., Tessier, D., Lapillonne, A., Chang, B. H. J., Quast, M. J., Gorenstein, D., Chen, K.-H., and Chan, L. (2000) Nat. Genet. 26, 474-479
3. Tansey, J. T., Sztalryd, C., Gruia-Gray, J., Roush, D. L., Zee, J. V., Gavrilova, O., Reitman, M. L., Deng, C.-X., Li, C., Kimmel, A. R., and Londos, C. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6494-6499
4. Greenberg, A. S., Egan, J. J., Wek, S. A., Garty, N. B., Blanchette-Mackie, E. J., and Londos, C. (1991) J. Biol. Chem. 266, 11341-11346
5. Servetnick, D. A., Brasaemle, D. L., Gruia-Gray, J., Kimmel, A. R., Wolff, J., and Londos, C. (1995) J. Biol. Chem. 270, 16970-16973
6. Londos, C., Brasaemle, D. L., Schultz, C. J., Segrest, J. P., and Kimmel, A. R. (1999) Semin Cell Dev. Biol. 10, 51-58
7. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
8. Holm, C., Osterlund, T., Laurell, H., and Contreras, J. A. (2000) Annu. Rev. Nutr. 20, 365-393
9. Souza, S. C., Muliro, K. V., Liscum, L., Lien, P., Yamamoto, M. T., Schaffer, J. E., Dallal, G. E., Wang, X., Kraemer, F. B., Obin, M., and Greenberg, A. S. (2002) J. Biol. Chem. 277, 8267-8272
10. Souza, S. C., Moitoso de Vargas, L., Yamamoto, M. T., Lien, P., Franciosa, M. D., Moss, L. G., and Greenberg, A. S. (1998) J. Biol. Chem. 273, 24665-24669
11. Chang, B. H.-J., Liao, W., Li, L., Nakamuta, M., Mack, D., and Chan, L. (1999) J. Biol. Chem. 274, 6051-6055
12. Miyake, K., Ogawa, W., Matsumoto, M., Nakamura, T., Sakaue, H., and Kasuga, M. (2002) J. Clin. Investig. 110, 1483-1491
13. Alam, N., and Saggerson, E. D. (1998) Biochem. J. 334, 233-241
14. Hong, R., Zarnowski, M. J., Cushman, S. W., and Lodish, H. F. (2003) J. Biol. Chem. 278, 47585-47593
15. Ma, K., Cabrero, A., Saha, P. K., Kojima, H., Li, L., Chang, B. H.-J., Paul, A., and Chan, L. (2002) J. Biol. Chem. 277, 34658-34661
16. Jones, J. P., and Dohm, G. L. (1997) Am. J. Physiol. 273, E682-E687
17. Lau, P. P., Villanueva, H., Kobayashi, K., Nakamuta, M., Chang, B. H. J., and Chan, L. (2001) J. Biol. Chem. 276, 46445-46452
18. Sunehag, A., Ewald, U., and Gustafsson, J. (1996) Pediatr. Res. 36, 550-557
19. Fjeld, C. R., Cole, F. S., and Bier, D. M. (1992) Pediatr. Res. 32, 693-698
20. Kim, J. K., Gavrilova, O., Chen, Y., Reitman, M. L., and Shulman, G. I. (2000) J. Biol. Chem. 275, 8456-8460
21. Rossetti, L., and Giaccari, A. (1990) J. Clin. Investig. 85, 1785-1792
22. Fujita, Y., Kojima, H., Hidaka, H., Fujimiya, M., Kashiwagi, A., and Kikkawa, R. (1998) Diabetologia 41, 1459-1466
23. Sunehag, A. L., Haymond, M. W., Schanler, R. J., Reeds, P. J., and Bier, D. M. (1999) Diabetes 48, 791-800
24. Bier, D. M., Sherman, W. R., Holland, W. H., Holmes, W. F., and Kipnis, D. M. (1996) Diabetes 26, 1005-1015
25. Bougneres, P. F. (1987) Biol. Neonate 2, 87-96
26. Bougneres, P. F., Hillman, L. S., and Bier, D. M. (1982) J. Clin. Investig. 70, 262-270
27. Patel, D., and Kalhan, S. (1992) Pediatr. Res. 31, 52-58
28. Bruning, J. C., Michael, M. D., Winnay, J. N., Hayashi, T., Horsch, D., Accili, D., Goodyear, L. J., and Kahn, C. R. (1998) Mol. Cell 2, 559-569
29. Ihlemann, J., Ploug, T., Hellsten, Y., and Galbo, H. (1999) Am. J. Physiol. 277, E208-E214
30. Abu-Elheiga, L., Matzuk, M. M., Abo-Hashema, K. A. H., and Wakil, S. J. (2001) Science 291, 2613-2616
31. Kunau, W. H., Dommes, V., and Schulz, H. (1995) Prog. Lipid Res. 34, 267-342
32. Argyropoulos, G., and Harper, M. E. (2002) J. Appl. Physiol. 92, 2187-2198
33. Banerjee, R. R., Rangwala, S. M., Shapiro, J. S., Rich, A. S., Rhoades, B., Qi, Y., Wang, J., Rajala, M. W., Pocai, A., Scherer, P. E., Steppan, C. M., Ahima, R. S., Obici, S., Rossetti, L., and Lazar, M. A. (2004) Science 303, 1195-1198
34. Kim, J. K., Zisman, A., Fillmore, J. J., Peroni, O. D., Kotani, K., Perret, P., Zong, H., Dong, J., Kahn, C. R., Kahn, B. B., and Shulman, G. I. (2001) J. Clin. Investig. 108, 153-160
35. Yamauchi, T., Kamon, J., Waki, H., Imai, Y., Shimozawa, N., Hioki, K., Uchida, S., Ito, Y., Takakuwa, K., Matsui, J., Takata, M., Eto, K., Terauchi, Y., Komeda, K., Tsunoda, M., Murakami, K., Ohnishi, Y., Naitoh, T., Yamamura, K., Ueyama, Y., Froguel, P., Kimura, S., Nagai, R., and Kadowaki, T. (2003) J. Biol. Chem. 278, 2461-2468
36. Pajvani, U. B., Hawkins, M., Combs, T. P., Rajala, M. W., Doebber, T., Berger, J. P., Wagner, J. A., Wu, M., Knopps, A., Xiang, A. H., Utzschneider, K. M., Kahn, S. E., Olefsky, J. M., Buchanan, T. A., and Scherer, P. E. (2004) J. Biol. Chem. 279, 12152-12162
37. Abel, E. D., Peroni, O., Kim, J. K., Kim, Y.-B., Boss, O., Hadro, E., Minnemann, T., Shulman, G. I., and Kahn, B. B. (2001) Nature 409, 729-733
38. Shepherd, P. R., Gnudi, L., Tozzo, E., Yang, H., Leach, F., and Kahn, B. B. (1993) J. Biol. Chem. 268, 22243-22246
39. Minokoshi, Y., Kahn, C. R., and Kahn, B. B. (2003) J. Biol. Chem. 278, 33609-33612
40. Yechoor, V. K., Patti, M. E., Saccone, R., and Kahn, C. R. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10587-10592
41. Chou, C. J., Haluzik, M., Gregory, C., Dietz, K. R., Vinson, C., Gavrilova, O., and Reitman, M. L. (2002) J. Biol. Chem. 277, 24484-24489
42. Shimomura, I., Hammer, R. E., Richardson, J. A., Ikemoto, S., Bashmakov, Y., Goldstein, J. L., and Brown, M. S. (1998) Genes Dev. 12, 3182-3194
43. Moitra, J., Mason, M. M., Olive, M., Krylov, D., Gavrilova, O., Marcus-Samuels, B., Feigenbaum, L., Lee, E., Aoyama, T., Eckhaus, M., Reitman, M. L., and Vinson, C. (1998) Genes Dev. 12, 3168-3181
44. Reitman, M. L. (2002) Annu. Rev. Nutr. 22, 459-482