-
1
-
-
0042707768
-
Screening for content - the evolution of high throughput
-
Dove, A. Screening for content - the evolution of high throughput. Nature Biotechnol. 21, 859-864 (2003).
-
(2003)
Nature Biotechnol
, vol.21
, pp. 859-864
-
-
Dove, A.1
-
2
-
-
36749021484
-
Linking microscopy and high content screening in large-scale biomedical research
-
Evans, J. G. & Matsudaira, P. Linking microscopy and high content screening in large-scale biomedical research. Methods Mol. Biol. 356, 33-38 (2007).
-
(2007)
Methods Mol. Biol
, vol.356
, pp. 33-38
-
-
Evans, J.G.1
Matsudaira, P.2
-
3
-
-
18844403391
-
High content screening for G protein-coupled receptors using cell-based protein translocation assays
-
Granas, C. et al. High content screening for G protein-coupled receptors using cell-based protein translocation assays. Comb. Chem. High Throughput Screen. 8, 301-309 (2005).
-
(2005)
Comb. Chem. High Throughput Screen
, vol.8
, pp. 301-309
-
-
Granas, C.1
-
4
-
-
33645464806
-
Cellular imaging in drug discovery
-
Lang, P., Yeow, K., Nichols, A. & Scheer, A. Cellular imaging in drug discovery. Nature Rev. Drug Discov. 5, 343-356 (2006).
-
(2006)
Nature Rev. Drug Discov
, vol.5
, pp. 343-356
-
-
Lang, P.1
Yeow, K.2
Nichols, A.3
Scheer, A.4
-
5
-
-
8444223104
-
Multidimensional drug profiling by automated microscopy
-
Perlman, Z. E. et al. Multidimensional drug profiling by automated microscopy. Science 306, 1194-1198 (2004).
-
(2004)
Science
, vol.306
, pp. 1194-1198
-
-
Perlman, Z.E.1
-
6
-
-
0035823254
-
Real-time molecular and cellular analysis: The new frontier of drug discovery
-
Taylor, D. L., Woo, E. S. & Giuliano, K. A. Real-time molecular and cellular analysis: the new frontier of drug discovery. Curr. Opin. Biotechnol. 12, 75-81 (2001).
-
(2001)
Curr. Opin. Biotechnol
, vol.12
, pp. 75-81
-
-
Taylor, D.L.1
Woo, E.S.2
Giuliano, K.A.3
-
7
-
-
33847629581
-
Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension
-
Curtis, M. A. et al. Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension. Science 315, 1243-1249 (2007).
-
(2007)
Science
, vol.315
, pp. 1243-1249
-
-
Curtis, M.A.1
-
8
-
-
34248684100
-
High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans
-
Burns, A. R. et al. High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans. Nature Protoc. 1, 1906-1914 (2006).
-
(2006)
Nature Protoc
, vol.1
, pp. 1906-1914
-
-
Burns, A.R.1
-
9
-
-
33750803554
-
An infrastructure for high-throughput microscopy: Instrumentation, informatics, and integration
-
Vaisberg, E. A., Lenzi, D., Hansen, R. L., Keon, B. H. & Finer, J. T. An infrastructure for high-throughput microscopy: instrumentation, informatics, and integration. Methods Enzymol. 414, 484-512 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 484-512
-
-
Vaisberg, E.A.1
Lenzi, D.2
Hansen, R.L.3
Keon, B.H.4
Finer, J.T.5
-
10
-
-
35148892720
-
Image-based high-throughput quantification of cellular fat accumulation
-
Dragunow, M., Cameron, R., Narayan, P. & O'Carroll, S. Image-based high-throughput quantification of cellular fat accumulation. J. Biomol. Screen. 12, 999-1005 (2007).
-
(2007)
J. Biomol. Screen
, vol.12
, pp. 999-1005
-
-
Dragunow, M.1
Cameron, R.2
Narayan, P.3
O'Carroll, S.4
-
11
-
-
34248177330
-
1-42-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands
-
1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands. Brain Res. 1151, 227-235 (2007).
-
(2007)
Brain Res
, vol.1151
, pp. 227-235
-
-
Hu, M.1
-
12
-
-
33744523910
-
A morphology- and kinetics-based cascade for human neural cell high content screening
-
Richards, G. R. et al. A morphology- and kinetics-based cascade for human neural cell high content screening. Assay Drug Dev. Technol. 4, 143-152 (2006).
-
(2006)
Assay Drug Dev. Technol
, vol.4
, pp. 143-152
-
-
Richards, G.R.1
-
13
-
-
33745005265
-
Automated semantic analysis of changes in image sequences of neurons in culture
-
Al-Kofahi, O., Radke, R. J., Roysam, B. & Banker, G. Automated semantic analysis of changes in image sequences of neurons in culture. IEEE Trans. Biomed. Eng. 53, 1109-1123 (2006).
-
(2006)
IEEE Trans. Biomed. Eng
, vol.53
, pp. 1109-1123
-
-
Al-Kofahi, O.1
Radke, R.J.2
Roysam, B.3
Banker, G.4
-
14
-
-
33644504878
-
Automated identification of axonal growth cones in time-lapse image sequences
-
Keenan, T. M. et al. Automated identification of axonal growth cones in time-lapse image sequences. J. Neurosci. Methods 151, 232-238 (2006).
-
(2006)
J. Neurosci. Methods
, vol.151
, pp. 232-238
-
-
Keenan, T.M.1
-
15
-
-
0041968413
-
Automated screening of neurite outgrowth
-
Ramm, P. et al. Automated screening of neurite outgrowth. J. Biomol. Screen. 8, 7-18 (2003).
-
(2003)
J. Biomol. Screen
, vol.8
, pp. 7-18
-
-
Ramm, P.1
-
16
-
-
33644956357
-
A simple, flexible, nonfluorescent system for the automated screening of neurite outgrowth
-
Price, R. D., Oe, T., Yamaji, T. & Matsuoka, N. A simple, flexible, nonfluorescent system for the automated screening of neurite outgrowth. J. Biomol. Screen. 11, 155-164 (2006).
-
(2006)
J. Biomol. Screen
, vol.11
, pp. 155-164
-
-
Price, R.D.1
Oe, T.2
Yamaji, T.3
Matsuoka, N.4
-
17
-
-
35349006437
-
Automated analysis of neurite branching in cultured cortical neurons using HCA-Vision
-
Vallotton, P. et al. Automated analysis of neurite branching in cultured cortical neurons using HCA-Vision. Cytometry A 71, 889-895 (2007).
-
(2007)
Cytometry A
, vol.71
, pp. 889-895
-
-
Vallotton, P.1
-
18
-
-
34548040659
-
The effect of neurodegenerative diseases on the subventricular zone
-
Curtis, M. A., Faull, R. L. & Eriksson, P. S. The effect of neurodegenerative diseases on the subventricular zone. Nature Rev. Neurosci. 8, 712-723 (2007).
-
(2007)
Nature Rev. Neurosci
, vol.8
, pp. 712-723
-
-
Curtis, M.A.1
Faull, R.L.2
Eriksson, P.S.3
-
19
-
-
32244445804
-
Automated cell lineage construction: A rapid method to analyze clonal development established with murine neural progenitor cells
-
Al-Kofahi, O. et al. Automated cell lineage construction: a rapid method to analyze clonal development established with murine neural progenitor cells. Cell Cycle 5, 327-335 (2006).
-
(2006)
Cell Cycle
, vol.5
, pp. 327-335
-
-
Al-Kofahi, O.1
-
20
-
-
0037154211
-
Synaptophysin regulates activity-dependent synapse formation in cultured hippocampal neurons
-
Tarsa, L. & Goda, Y. Synaptophysin regulates activity-dependent synapse formation in cultured hippocampal neurons. Proc. Natl Acad. Sci. USA 99, 1012-1016 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 1012-1016
-
-
Tarsa, L.1
Goda, Y.2
-
21
-
-
34548324511
-
Delayed peripheral administration of a GPE analogue induces astrogliosis and angiogenesis and reduces inflammation and brain injury following hypoxia-ischemia in the neonatal rat
-
Svedin, P. et al. Delayed peripheral administration of a GPE analogue induces astrogliosis and angiogenesis and reduces inflammation and brain injury following hypoxia-ischemia in the neonatal rat. Dev. Neurosci. 29, 393-402 (2007).
-
(2007)
Dev. Neurosci
, vol.29
, pp. 393-402
-
-
Svedin, P.1
-
22
-
-
34347333382
-
High throughput quantification of cells with complex morphology in mixed cultures
-
Narayan, P. J., Gibbons, H. M., Mee, E. W., Faull, R. L. & Dragunow, M. High throughput quantification of cells with complex morphology in mixed cultures. J. Neurosci. Methods 164, 339-349 (2007).
-
(2007)
J. Neurosci. Methods
, vol.164
, pp. 339-349
-
-
Narayan, P.J.1
Gibbons, H.M.2
Mee, E.W.3
Faull, R.L.4
Dragunow, M.5
-
23
-
-
33845209203
-
BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation
-
Rev
-
Taupin, P. BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res. Rev. 53, 198-214 (2007).
-
(2007)
Brain Res
, vol.53
, pp. 198-214
-
-
Taupin, P.1
-
24
-
-
33747247603
-
The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells
-
Lind, C. R. et al. The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells. Neuroscience 141, 1925-1933 (2006).
-
(2006)
Neuroscience
, vol.141
, pp. 1925-1933
-
-
Lind, C.R.1
-
25
-
-
33745226457
-
Valproic acid induces caspase 3-mediated apoptosis in microglial cells
-
Dragunow, M. et al. Valproic acid induces caspase 3-mediated apoptosis in microglial cells. Neuroscience 140, 1149-1156 (2006).
-
(2006)
Neuroscience
, vol.140
, pp. 1149-1156
-
-
Dragunow, M.1
-
26
-
-
18744415469
-
Stem cell proliferative history in tissue revealed by temporal halogenated thymidine analog discrimination
-
Vega, C. J. & Peterson, D. A. Stem cell proliferative history in tissue revealed by temporal halogenated thymidine analog discrimination. Nature Methods 2, 167-169 (2005).
-
(2005)
Nature Methods
, vol.2
, pp. 167-169
-
-
Vega, C.J.1
Peterson, D.A.2
-
27
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Rev. Neurosci. 4, 49-60 (2003).
-
(2003)
Nature Rev. Neurosci
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
28
-
-
42749089622
-
High throughput quantification of mutant huntingtin aggregates
-
Scotter, E. L., Narayan, P., Glass, M. & Dragunow, M. High throughput quantification of mutant huntingtin aggregates. J. Neurosci. Methods 171, 174-179 (2008).
-
(2008)
J. Neurosci. Methods
, vol.171
, pp. 174-179
-
-
Scotter, E.L.1
Narayan, P.2
Glass, M.3
Dragunow, M.4
-
29
-
-
57649229012
-
A standardized method to automatically segment amyloid plaques in Congo Red stained sections from Alzheimer transgenic mice
-
Teboul, O. et al. A standardized method to automatically segment amyloid plaques in Congo Red stained sections from Alzheimer transgenic mice. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2007, 5593-5596 (2007).
-
(2007)
Conf. Proc. IEEE Eng. Med. Biol. Soc
, vol.2007
, pp. 5593-5596
-
-
Teboul, O.1
-
30
-
-
33747798001
-
BioVision: An application for the automated image analysis of histological sections
-
Chubb, C. et al. BioVision: an application for the automated image analysis of histological sections. Neurobiol. Aging 27, 1462-1476 (2006).
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1462-1476
-
-
Chubb, C.1
-
31
-
-
37649024076
-
Small molecule regulators of autophagy identified by an image-based high-throughput screen
-
Zhang, L. et al. Small molecule regulators of autophagy identified by an image-based high-throughput screen. Proc. Natl Acad. Sci. USA 104, 19023-19028 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 19023-19028
-
-
Zhang, L.1
-
32
-
-
33847668394
-
Image-based screening for the identification of novel proteasome inhibitors
-
Rickardson, L., Wickstrom, M., Larsson, R. & Lovborg, H. Image-based screening for the identification of novel proteasome inhibitors. J. Biomol. Screen. 12, 203-210 (2007).
-
(2007)
J. Biomol. Screen
, vol.12
, pp. 203-210
-
-
Rickardson, L.1
Wickstrom, M.2
Larsson, R.3
Lovborg, H.4
-
33
-
-
42749089622
-
High throughput quantification of mutant huntingtin aggregates
-
Scotter, E. L., Narayan, P., Glass, M. & Dragunow, M. High throughput quantification of mutant huntingtin aggregates. J. Neurosci. Methods 171, 174-179 (2008).
-
(2008)
J. Neurosci. Methods
, vol.171
, pp. 174-179
-
-
Scotter, E.L.1
Narayan, P.2
Glass, M.3
Dragunow, M.4
-
34
-
-
35848945494
-
Reconsidering the mechanism of polyglutamine peptide aggregation
-
Lee, C. C., Walters, R. H. & Murphy, R. M. Reconsidering the mechanism of polyglutamine peptide aggregation. Biochemistry 46, 12810-12820 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 12810-12820
-
-
Lee, C.C.1
Walters, R.H.2
Murphy, R.M.3
-
35
-
-
33846604677
-
Key note lecture: Toward a mechanistic taxonomy for cell death programs
-
Bredesen, D. E. Key note lecture: toward a mechanistic taxonomy for cell death programs. Stroke 38, 652-660 (2007).
-
(2007)
Stroke
, vol.38
, pp. 652-660
-
-
Bredesen, D.E.1
-
36
-
-
33646229338
-
Multiparameter measurement of caspase 3 activation and apoptotic cell death in NT2 neuronal precursor cells using high-content analysis
-
Fennell, M., Chan, H. & Wood, A. Multiparameter measurement of caspase 3 activation and apoptotic cell death in NT2 neuronal precursor cells using high-content analysis. J. Biomol. Screen. 11, 296-302 (2006).
-
(2006)
J. Biomol. Screen
, vol.11
, pp. 296-302
-
-
Fennell, M.1
Chan, H.2
Wood, A.3
-
37
-
-
41849099259
-
Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening
-
Huang, R. et al. Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening. Chem. Res. Toxicol. 21, 659-667 (2008).
-
(2008)
Chem. Res. Toxicol
, vol.21
, pp. 659-667
-
-
Huang, R.1
-
38
-
-
34547555822
-
Extracellular signal-regulated kinase involvement in human astrocyte migration
-
Lim, J. H. et al. Extracellular signal-regulated kinase involvement in human astrocyte migration. Brain Res. 1164, 1-13 (2007).
-
(2007)
Brain Res
, vol.1164
, pp. 1-13
-
-
Lim, J.H.1
-
39
-
-
13244255307
-
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods
-
Yarrow, J. C., Perlman, Z. E., Westwood, N. J. & Mitchison, T. J. A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. BMC Biotechnol. 4, 21 (2004).
-
(2004)
BMC Biotechnol
, vol.4
, pp. 21
-
-
Yarrow, J.C.1
Perlman, Z.E.2
Westwood, N.J.3
Mitchison, T.J.4
-
40
-
-
10244247852
-
Quantitative assays of chemotaxis and chemokinesis for human neural cells
-
Richards, G. R., Millard, R. M., Leveridge, M., Kerby, J. & Simpson, P. B. Quantitative assays of chemotaxis and chemokinesis for human neural cells. Assay Drug Dev. Technol. 2, 465-472 (2004).
-
(2004)
Assay Drug Dev. Technol
, vol.2
, pp. 465-472
-
-
Richards, G.R.1
Millard, R.M.2
Leveridge, M.3
Kerby, J.4
Simpson, P.B.5
-
41
-
-
33644519960
-
Astrocyte dysfunction in neurological disorders: A molecular perspective
-
Seifert, G., Schilling, K. & Steinhauser, C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nature Rev. Neurosci. 7, 194-206 (2006).
-
(2006)
Nature Rev. Neurosci
, vol.7
, pp. 194-206
-
-
Seifert, G.1
Schilling, K.2
Steinhauser, C.3
-
42
-
-
34548186903
-
Gap junction adhesion is necessary for radial migration in the neocortex
-
Elias, L. A., Wang, D. D. & Kriegstein, A. R. Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448, 901-907 (2007).
-
(2007)
Nature
, vol.448
, pp. 901-907
-
-
Elias, L.A.1
Wang, D.D.2
Kriegstein, A.R.3
-
43
-
-
1542598052
-
Identification of gap junction blockers using automated fluorescence microscopy imaging
-
Li, Z. et al. Identification of gap junction blockers using automated fluorescence microscopy imaging. J. Biomol. Screen. 8, 489-499 (2003).
-
(2003)
J. Biomol. Screen
, vol.8
, pp. 489-499
-
-
Li, Z.1
-
44
-
-
33750822293
-
G protein-coupled receptor internalization assays in the high-content screening format
-
Haasen, D., Schnapp, A., Valler, M. J. & Heilker, R. G protein-coupled receptor internalization assays in the high-content screening format. Methods Enzymol. 414, 121-139 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 121-139
-
-
Haasen, D.1
Schnapp, A.2
Valler, M.J.3
Heilker, R.4
-
45
-
-
54249170562
-
-
Grimsey, N. L., Narayan, P. J., Dragunow, M. & Glass, M. Novel high-throughput assay for the quantitative assessment of receptor trafficking. Clin. Exp. Pharmacol. Physiol. 28 Jun 2008 (10.1111/j.1440-1681.2008. 04991.x).
-
Grimsey, N. L., Narayan, P. J., Dragunow, M. & Glass, M. Novel high-throughput assay for the quantitative assessment of receptor trafficking. Clin. Exp. Pharmacol. Physiol. 28 Jun 2008 (10.1111/j.1440-1681.2008. 04991.x).
-
-
-
-
46
-
-
34147192708
-
i-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay
-
i-coupled receptor in a 2.2-microl 3,456-well plate format cyclicAMP assay. Assay Drug Dev. Technol. 5, 117-125 (2007).
-
(2007)
Assay Drug Dev. Technol
, vol.5
, pp. 117-125
-
-
Weber, M.1
-
47
-
-
33947401068
-
β-arrestins and cell signaling
-
DeWire, S. M., Ahn, S., Lefkowitz, R. J. & Shenoy, S. K. β-arrestins and cell signaling. Annu. Rev. Physiol. 69, 483-510 (2007).
-
(2007)
Annu. Rev. Physiol
, vol.69
, pp. 483-510
-
-
DeWire, S.M.1
Ahn, S.2
Lefkowitz, R.J.3
Shenoy, S.K.4
-
48
-
-
33750837563
-
High-content screening of known G protein-coupled receptors by arrestin translocation
-
Hudson, C. C., Oakley, R. H., Sjaastad, M. D. & Loomis, C. R. High-content screening of known G protein-coupled receptors by arrestin translocation. Methods Enzymol. 414, 63-78 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 63-78
-
-
Hudson, C.C.1
Oakley, R.H.2
Sjaastad, M.D.3
Loomis, C.R.4
-
49
-
-
33750819442
-
The ligand-independent translocation assay: An enabling technology for screening orphan G protein-coupled receptors by arrestin recruitment
-
Oakley, R. H., Hudson, C. C., Sjaastad, M. D. & Loomis, C. R. The ligand-independent translocation assay: an enabling technology for screening orphan G protein-coupled receptors by arrestin recruitment. Methods Enzymol. 414, 50-63 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 50-63
-
-
Oakley, R.H.1
Hudson, C.C.2
Sjaastad, M.D.3
Loomis, C.R.4
-
50
-
-
46149091496
-
Multiplexed assays by high-content imaging for assessment of GPCR activity
-
Ross, D. A. et al. Multiplexed assays by high-content imaging for assessment of GPCR activity. J. Biomol. Screen. 13, 449-455 (2008).
-
(2008)
J. Biomol. Screen
, vol.13
, pp. 449-455
-
-
Ross, D.A.1
-
51
-
-
33750835941
-
High-content kinetic calcium imaging in drug-sensitive and drug-resistant human breast cancer cells
-
DeBernardi, M. A. & Brooker, G. High-content kinetic calcium imaging in drug-sensitive and drug-resistant human breast cancer cells. Methods Enzymol. 414, 317-335 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 317-335
-
-
DeBernardi, M.A.1
Brooker, G.2
-
52
-
-
33750830035
-
Measurement and analysis of calcium signaling in heterogeneous cell cultures
-
Richards, G. R., Jack, A. D., Platts, A. & Simpson, P. B. Measurement and analysis of calcium signaling in heterogeneous cell cultures. Methods Enzymol. 414, 335-347 (2006).
-
(2006)
Methods Enzymol
, vol.414
, pp. 335-347
-
-
Richards, G.R.1
Jack, A.D.2
Platts, A.3
Simpson, P.B.4
-
53
-
-
33749421223
-
Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway
-
Graham, E. S. et al. Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway. J. Biol. Chem. 281, 29085-29095 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 29085-29095
-
-
Graham, E.S.1
-
54
-
-
6944247437
-
Detection and classification of threat agents via high-content assays of mammalian cells
-
Tencza, S. B. & Sipe, M. A. Detection and classification of threat agents via high-content assays of mammalian cells. J. Appl. Toxicol. 24, 371-377 (2004).
-
(2004)
J. Appl. Toxicol
, vol.24
, pp. 371-377
-
-
Tencza, S.B.1
Sipe, M.A.2
-
55
-
-
33646261138
-
Automated interpretation of protein subcellular location patterns
-
Chen, X. & Murphy, R. F. Automated interpretation of protein subcellular location patterns. Int. Rev. Cytol. 249, 193-227 (2006).
-
(2006)
Int. Rev. Cytol
, vol.249
, pp. 193-227
-
-
Chen, X.1
Murphy, R.F.2
-
56
-
-
2942620741
-
Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer
-
George, T. C. et al. Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer. Cytometry A 59, 237-245 (2004).
-
(2004)
Cytometry A
, vol.59
, pp. 237-245
-
-
George, T.C.1
-
57
-
-
33646096984
-
Quantitative measurement of nuclear translocation events using similarity analysis of multispectral cellular images obtained in flow
-
George, T. C. et al. Quantitative measurement of nuclear translocation events using similarity analysis of multispectral cellular images obtained in flow. J. Immunol. Methods 311, 117-129 (2006).
-
(2006)
J. Immunol. Methods
, vol.311
, pp. 117-129
-
-
George, T.C.1
-
58
-
-
0346958238
-
Tissue microarrays in drug discovery
-
Sauter, G., Simon, R. & Hillan, K. Tissue microarrays in drug discovery. Nature Rev. Drug Discov. 2, 962-972 (2003).
-
(2003)
Nature Rev. Drug Discov
, vol.2
, pp. 962-972
-
-
Sauter, G.1
Simon, R.2
Hillan, K.3
-
59
-
-
4444278712
-
Perspectives in tissue microarrays
-
Braunschweig, T., Chung, J. Y. & Hewitt, S. M. Perspectives in tissue microarrays. Comb. Chem. High Throughput Screen. 7, 575-585 (2004).
-
(2004)
Comb. Chem. High Throughput Screen
, vol.7
, pp. 575-585
-
-
Braunschweig, T.1
Chung, J.Y.2
Hewitt, S.M.3
-
60
-
-
33748356886
-
Human brain tissue microarrays as a platform to investigate diseases of the nervous system
-
Martikainen, P., Louhelainen, A. M., Kauppinen, T. & Alafuzoff, I. Human brain tissue microarrays as a platform to investigate diseases of the nervous system. Brain Res. 1089, 33-43 (2006).
-
(2006)
Brain Res
, vol.1089
, pp. 33-43
-
-
Martikainen, P.1
Louhelainen, A.M.2
Kauppinen, T.3
Alafuzoff, I.4
-
61
-
-
35848938933
-
Brain tissue microarrays in neurodegenerative diseases: Validation of methodology and immunohistochemical study of growth-associated protein-43 and calretinin
-
Takei, H., Buckleair, L. W., Rivera, A. & Powell, S. Z. Brain tissue microarrays in neurodegenerative diseases: validation of methodology and immunohistochemical study of growth-associated protein-43 and calretinin. Pathol. Int. 57, 775-783 (2007).
-
(2007)
Pathol. Int
, vol.57
, pp. 775-783
-
-
Takei, H.1
Buckleair, L.W.2
Rivera, A.3
Powell, S.Z.4
-
62
-
-
0036840216
-
Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays
-
Liu, C. L. et al. Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am. J. Pathol. 161, 1557-1565 (2002).
-
(2002)
Am. J. Pathol
, vol.161
, pp. 1557-1565
-
-
Liu, C.L.1
-
63
-
-
0036852721
-
Automated subcellular localization and quantification of protein expression in tissue microarrays
-
Camp, R. L., Chung, G. G. & Rimm, D. L. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nature Med. 8, 1323-1327 (2002).
-
(2002)
Nature Med
, vol.8
, pp. 1323-1327
-
-
Camp, R.L.1
Chung, G.G.2
Rimm, D.L.3
-
64
-
-
33644777646
-
Lab-on-a-chip: Microfluidics in drug discovery
-
Dittrich, P. S. & Manz, A. Lab-on-a-chip: microfluidics in drug discovery. Nature Rev. Drug Discov. 5, 210-218 (2006).
-
(2006)
Nature Rev. Drug Discov
, vol.5
, pp. 210-218
-
-
Dittrich, P.S.1
Manz, A.2
-
65
-
-
33747116681
-
Cells on chips
-
El-Ali, J., Sorger, P. K. & Jensen, K. F. Cells on chips. Nature 442, 403-411 (2006).
-
(2006)
Nature
, vol.442
, pp. 403-411
-
-
El-Ali, J.1
Sorger, P.K.2
Jensen, K.F.3
-
66
-
-
0035799654
-
Microarrays of cells expressing defined cDNAs
-
Ziauddin, J. & Sabatini, D. M. Microarrays of cells expressing defined cDNAs. Nature 411, 107-110 (2001).
-
(2001)
Nature
, vol.411
, pp. 107-110
-
-
Ziauddin, J.1
Sabatini, D.M.2
-
67
-
-
34347220153
-
Reverse transfection on cell arrays for high content screening microscopy
-
Erfle, H. et al. Reverse transfection on cell arrays for high content screening microscopy. Nature Protoc. 2, 392-399 (2007).
-
(2007)
Nature Protoc
, vol.2
, pp. 392-399
-
-
Erfle, H.1
-
68
-
-
33646057010
-
High-throughput RNAi screening by time-lapse imaging of live human cells
-
Neumann, B. et al. High-throughput RNAi screening by time-lapse imaging of live human cells. Nature Methods 3, 385-390 (2006).
-
(2006)
Nature Methods
, vol.3
, pp. 385-390
-
-
Neumann, B.1
-
69
-
-
21544458021
-
Mammalian electrophysiology on a microfluidic platform
-
Ionescu-Zanetti, C. et al. Mammalian electrophysiology on a microfluidic platform. Proc. Natl Acad. Sci. USA 102, 9112-9117 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 9112-9117
-
-
Ionescu-Zanetti, C.1
-
70
-
-
34447125022
-
Automated analysis of FISH and immunohistochemistry images: A review
-
Theodosiou, Z. et al. Automated analysis of FISH and immunohistochemistry images: a review. Cytometry A 71, 439-450 (2007).
-
(2007)
Cytometry A
, vol.71
, pp. 439-450
-
-
Theodosiou, Z.1
-
71
-
-
0036065158
-
Muscarinic receptor-mediated phosphorylation of cyclic AMP response element binding protein in human neuroblastoma cells
-
Greenwood, J. M. & Dragunow, M. Muscarinic receptor-mediated phosphorylation of cyclic AMP response element binding protein in human neuroblastoma cells. J. Neurochem. 82, 389-397 (2002).
-
(2002)
J. Neurochem
, vol.82
, pp. 389-397
-
-
Greenwood, J.M.1
Dragunow, M.2
-
72
-
-
18244406829
-
Whole brain segmentation: Automated labeling of neuroanatomical structures in the human brain
-
Fischl, B. et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 33, 341-355 (2002).
-
(2002)
Neuron
, vol.33
, pp. 341-355
-
-
Fischl, B.1
-
73
-
-
36549058721
-
High throughput microscopy: From raw images to discoveries
-
Wollman, R. & Stuurman, N. High throughput microscopy: from raw images to discoveries. J. Cell Sci. 120, 3715-3722 (2007).
-
(2007)
J. Cell Sci
, vol.120
, pp. 3715-3722
-
-
Wollman, R.1
Stuurman, N.2
-
74
-
-
19744364589
-
Analyzing and mining image databases
-
Berlage, T. Analyzing and mining image databases. Drug Discov. Today 10, 795-802 (2005).
-
(2005)
Drug Discov. Today
, vol.10
, pp. 795-802
-
-
Berlage, T.1
-
75
-
-
33645732240
-
Modeling cellular machinery through biological network comparison
-
Sharan, R. & Ideker, T. Modeling cellular machinery through biological network comparison. Nature Biotechnol. 24, 427-433 (2006).
-
(2006)
Nature Biotechnol
, vol.24
, pp. 427-433
-
-
Sharan, R.1
Ideker, T.2
-
76
-
-
34548482697
-
Cellular composition of human glial cultures from adult biopsy brain tissue
-
Gibbons, H. M. et al. Cellular composition of human glial cultures from adult biopsy brain tissue. J. Neurosci. Methods 166, 89-98 (2007).
-
(2007)
J. Neurosci. Methods
, vol.166
, pp. 89-98
-
-
Gibbons, H.M.1
-
77
-
-
19444375908
-
Activating transcription factor 2 expression in the adult human brain: Association with both neurodegeneration and neurogenesis
-
Pearson, A. G., Curtis, M. A., Waldvogel, H. J., Faull, R. L. & Dragunow, M. Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis. Neuroscience 133, 437-451 (2005).
-
(2005)
Neuroscience
, vol.133
, pp. 437-451
-
-
Pearson, A.G.1
Curtis, M.A.2
Waldvogel, H.J.3
Faull, R.L.4
Dragunow, M.5
|