-
2
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti, F. and Dobson, C. M. (2006) Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 75, 333-366.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
3
-
-
0001451739
-
Zur celluslose-frage
-
Virchow, R. (1854) Zur celluslose-frage. Virchows Arch. 6, 415-426.
-
(1854)
Virchows Arch
, vol.6
, pp. 415-426
-
-
Virchow, R.1
-
4
-
-
0347987853
-
Folding proteins in fatal ways
-
Selkoe, D. J. (2003) Folding proteins in fatal ways. Nature 426, 900-904.
-
(2003)
Nature
, vol.426
, pp. 900-904
-
-
Selkoe, D.J.1
-
5
-
-
0036527699
-
Therapeutic strategies for human amyloid diseases
-
Sacchettini, J. C. and Kelly, J. W. (2002) Therapeutic strategies for human amyloid diseases. Nat. Rev. Drug. Discov. 1, 267-275.
-
(2002)
Nat. Rev. Drug. Discov.
, vol.1
, pp. 267-275
-
-
Sacchettini, J.C.1
Kelly, J.W.2
-
6
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy, J. and Selkoe, D. J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
8
-
-
0042709605
-
Molecular mechanisms of amyloidosis
-
Merlini, G. and Bellotti, V. (2003) Molecular mechanisms of amyloidosis. N. Engl. J. Med. 349, 583-596.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 583-596
-
-
Merlini, G.1
Bellotti, V.2
-
9
-
-
0037130174
-
Amyloid pores from pathogenic mutations
-
Lashuel, H. A., Hartley, D., Petre, B. M., Walz, T. and Lansbury, P. T. Jr. (2002) Amyloid pores from pathogenic mutations. Nature 418, 291.
-
(2002)
Nature
, vol.418
, pp. 291
-
-
Lashuel, H.A.1
Hartley, D.2
Petre, B.M.3
Walz, T.4
Lansbury P.T., Jr.5
-
10
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
-
Caughey, B. and Lansbury, P. T. Jr. (2003) Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu. Rev. Neurosci. 26, 267-298.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury P.T., Jr.2
-
11
-
-
0033601338
-
Cu(II) potentiation of Alzheimer Ab neurotoxicity
-
Huang, X., Cuajungco, M. P., Atwood, C. S., Hartshorn, M. A., Tyndall, J. D. A., Hanson, G. R., Stokes, K. C., Leopold, M., Multhaup, G., Goldstein, L. E., Scarpa, R. C., Saunders, A. J., Lim, J., Moir, R. D., Glabe, C., Bowden, E. F., Masters, C. L., Fairlie, D. P., Tanzi, R. E. and Bush, A. I. (1999) Cu(II) potentiation of Alzheimer Ab neurotoxicity. J. Biol. Chem. 274, 37111-37116.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.D.A.5
Hanson, G.R.6
Stokes, K.C.7
Leopold, M.8
Multhaup, G.9
Goldstein, L.E.10
Scarpa, R.C.11
Saunders, A.J.12
Lim, J.13
Moir, R.D.14
Glabe, C.15
Bowden, E.F.16
Masters, C.L.17
Fairlie, D.P.18
Tanzi, R.E.19
Bush, A.I.20
more..
-
12
-
-
18344414746
-
The Ab peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang, X., Atwood, C. S., Hartshorn, M. A., Multhaup, G., Goldstein, L. E., Scarpa, R. C., Cuajungco, M. P., Gray, D. N., Lim, J., Moir, R. D., Tanzi, R. E. and Bush, A. I. (1999) The Ab peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38, 7609-7616.
-
(1999)
Biochemistry
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
13
-
-
0034733705
-
Evidence that the b-amyloid plaques of Alzhermer's disease represent the redox-silencing and entombment of Ab by zinc
-
Cuajungco, M. P., Goldstein, L. E., Nunomura, A., Smith, M. A., Lim, J. T., Atwood, C. S., Huang, X., Farrag, Y. W., Perry, G. and Bush, A. I. (2000) Evidence that the b-amyloid plaques of Alzhermer's disease represent the redox-silencing and entombment of Ab by zinc. J. Biol. Chem. 275, 19439-19442.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19439-19442
-
-
Cuajungco, M.P.1
Goldstein, L.E.2
Nunomura, A.3
Smith, M.A.4
Lim, J.T.5
Atwood, C.S.6
Huang, X.7
Farrag, Y.W.8
Perry, G.9
Bush, A.I.10
-
14
-
-
0037174856
-
Metalloenzyme-like activity of Alzheimer's disease β-amyloid
-
Opazo, C., Huang, X., Cherny, R. A., Moir, R. D., Roher, A. E., White, A. R., Cappai, R., Masters, C. L., Tanzi, R. E., Inestrosa, N. C. and Bush, A. I. (2002) Metalloenzyme-like activity of Alzheimer's disease β-amyloid. J. Biol. Chem. 277, 40302-40308.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40302-40308
-
-
Opazo, C.1
Huang, X.2
Cherny, R.A.3
Moir, R.D.4
Roher, A.E.5
White, A.R.6
Cappai, R.7
Masters, C.L.8
Tanzi, R.E.9
Inestrosa, N.C.10
Bush, A.I.11
-
15
-
-
0242290357
-
Neurotoxic, redox-competent Alzheimer's b-amyloid is released from lipid membrane by methionine oxidation
-
Barnham, K. J., Ciccotosto, G. D., Tickler, A. K., Ali, F. E., Smith, D. G., Williamson, N. A., Lam, Y. -H., Carrington, D., Tew, D., Kocak, G., Volitakis, I., Separovic, F., Barrow, C. J., Wade, J. D., Masters, C. L., Cherny, R. A., Curtain, C. C., Bush, A. I. and Cappai, R. (2003) Neurotoxic, redox-competent Alzheimer's b-amyloid is released from lipid membrane by methionine oxidation. J. Biol. Chem. 278, 42959-42965.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42959-42965
-
-
Barnham, K.J.1
Ciccotosto, G.D.2
Tickler, A.K.3
Ali, F.E.4
Smith, D.G.5
Williamson, N.A.6
Lam, Y.-H.7
Carrington, D.8
Tew, D.9
Kocak, G.10
Volitakis, I.11
Separovic, F.12
Barrow, C.J.13
Wade, J.D.14
Masters, C.L.15
Cherny, R.A.16
Curtain, C.C.17
Bush, A.I.18
Cappai, R.19
-
16
-
-
34247899121
-
Functional amyloid - from bacteria to humans
-
Fowler, D. M., Koulov, A. V., Balch, W. E. and Kelly, J. W. (2007) Functional amyloid - from bacteria to humans. Trends Biochem. Sci. 32, 217-224.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 217-224
-
-
Fowler, D.M.1
Koulov, A.V.2
Balch, W.E.3
Kelly, J.W.4
-
18
-
-
0033591467
-
Bacterial biofilms: a common cause of persistent infections
-
Costerton, J. W., Stewart, P. S. and Greenberg, E. P. (1999) Bacterial biofilms: a common cause of persistent infections. Science 284, 1318-1322.
-
(1999)
Science
, vol.284
, pp. 1318-1322
-
-
Costerton, J.W.1
Stewart, P.S.2
Greenberg, E.P.3
-
19
-
-
25444530659
-
Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adhearence to human uroepithelial cells
-
Kikuchi, T., Mizunoe, Y., Takade, A., Naito, S. and Yoshida, S. (2005) Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adhearence to human uroepithelial cells. Microbiol. Immunol. 49, 875-884.
-
(2005)
Microbiol. Immunol.
, vol.49
, pp. 875-884
-
-
Kikuchi, T.1
Mizunoe, Y.2
Takade, A.3
Naito, S.4
Yoshida, S.5
-
20
-
-
15944405779
-
Amyloids - a functional coat for microorganisms
-
Gebbink, M. F. B. G., Claessen, D., Bouma, B., Dijkhuizen, L. and Wösten, H. A. B. (2005) Amyloids - a functional coat for microorganisms. Nat. Rev. Microbiol. 3, 333-341.
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 333-341
-
-
Gebbink, M.F.B.G.1
Claessen, D.2
Bouma, B.3
Dijkhuizen, L.4
Wösten, H.A.B.5
-
21
-
-
0141838884
-
Aerial morphogenesis: enter the chaplins
-
Talbot, N. J. (2003) Aerial morphogenesis: enter the chaplins. Curr. Biol. 13, R696-R698.
-
(2003)
Curr. Biol.
, vol.13
-
-
Talbot, N.J.1
-
22
-
-
0034683126
-
Amyloids protect the silkmoth oocyte and embryo
-
Iconomidou, V. A., Vriend, G. and Hamodrakas, S. J. (2000) Amyloids protect the silkmoth oocyte and embryo. FEBS Lett. 479, 141-145.
-
(2000)
FEBS Lett
, vol.479
, pp. 141-145
-
-
Iconomidou, V.A.1
Vriend, G.2
Hamodrakas, S.J.3
-
23
-
-
0035005523
-
Survival of water stress in annual fish embryos: dehydration avoidance and egg envelope amyloid fibers
-
Podrabsky, J. E., Carpenter, J. F. and Hand, S. C. (2001) Survival of water stress in annual fish embryos: dehydration avoidance and egg envelope amyloid fibers. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R123-R131.
-
(2001)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.280
-
-
Podrabsky, J.E.1
Carpenter, J.F.2
Hand, S.C.3
-
24
-
-
31144460030
-
Functional amyloid formation within mammalian tissue
-
Fowler, D. M., Koulov, A. V., Alory-Jost, C., Marks, M. S., Balch, W. E. and Kelly, J. W. (2006) Functional amyloid formation within mammalian tissue. PLoS Biol. 4, e6.
-
(2006)
PLoS Biol
, vol.4
-
-
Fowler, D.M.1
Koulov, A.V.2
Alory-Jost, C.3
Marks, M.S.4
Balch, W.E.5
Kelly, J.W.6
-
25
-
-
0032931038
-
Zinc-dependent activation of the plasma kinin-forming cascade by aggregated β?amyloid protein
-
Shibayama, Y., Joseph, K., Nakazawa, Y., Ghebreihiwet, B., Peerschke, E. I. B. and Kaplan, A. P. (1999) Zinc-dependent activation of the plasma kinin-forming cascade by aggregated β?amyloid protein. Clin. Immunol. 90, 89-99.
-
(1999)
Clin. Immunol.
, vol.90
, pp. 89-99
-
-
Shibayama, Y.1
Joseph, K.2
Nakazawa, Y.3
Ghebreihiwet, B.4
Peerschke, E.I.B.5
Kaplan, A.P.6
-
26
-
-
0031825554
-
From the globular to the fibrous state: protein structure and structural conversion in amyloid formation
-
Sunde, M. and Blake, C. C. F. (1998) From the globular to the fibrous state: protein structure and structural conversion in amyloid formation. Q. Rev. Biophys. 31, 1-39.
-
(1998)
Q. Rev. Biophys.
, vol.31
, pp. 1-39
-
-
Sunde, M.1
Blake, C.C.F.2
-
27
-
-
0031592945
-
Common core structure of amyloid fibrils by synchrotron X-ray diffraction
-
Sunde, M., Serpella, L. C., Bartlama, M., Frasera, P. E., Pepysa, M. B. and Blake, C. C. F. (1997) Common core structure of amyloid fibrils by synchrotron X-ray diffraction. J. Mol. Biol. 273, 729-739.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 729-739
-
-
Sunde, M.1
Serpella, L.C.2
Bartlama, M.3
Frasera, P.E.4
Pepysa, M.B.5
Blake, C.C.F.6
-
28
-
-
37549063068
-
Role of intermolecular forces in defining material properties of protein nanofibrils
-
Knowles, T. P., Fitzpatrick, A. W., Meehan, S., Mott, H. R., Vendruscolo, M., Dobson, C. M. and Welland, M. E. (2007) Role of intermolecular forces in defining material properties of protein nanofibrils. Science 318, 1900-1903.
-
(2007)
Science
, vol.318
, pp. 1900-1903
-
-
Knowles, T.P.1
Fitzpatrick, A.W.2
Meehan, S.3
Mott, H.R.4
Vendruscolo, M.5
Dobson, C.M.6
Welland, M.E.7
-
29
-
-
47049100201
-
Amyloids: Not only pathological agents but also ordered nanomaterials
-
Cherny, I. and Gazit, E. (2008) Amyloids: Not only pathological agents but also ordered nanomaterials. Angew. Chem. Int. Ed. 47, 4062-4069.
-
(2008)
Angew. Chem. Int. Ed.
, vol.47
, pp. 4062-4069
-
-
Cherny, I.1
Gazit, E.2
-
30
-
-
0141765883
-
Fabrication of novel biomaterials through molecular self-assembly
-
Zhang, S. (2003) Fabrication of novel biomaterials through molecular self-assembly. Nat. Biotechnol. 21, 1171-1178.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1171-1178
-
-
Zhang, S.1
-
31
-
-
0344490335
-
-M., Jaeger, H. and Lindquist, S. L
-
Scheibel, T., Parthasarathy, R., Sawicki, G., Lin, X. -M., Jaeger, H. and Lindquist, S. L. (2003) Conducting nanowires built by controlled self-assembly of amyloid fibers and selective metal deposition. Proc. Natl. Acad. Sci. U.S.A. 100, 4527-4532.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 4527-4532
-
-
Scheibel, T.1
Parthasarathy, R.2
Sawicki, G.3
Lin, X.4
-
32
-
-
2442718759
-
Synthesis of peptide-nanotube platinum-nanoparticle composites
-
Song, Y., Challa, S. R., Medforth, C. J., Qiu, Y., Watt, R. K., Peña, D., Miller, J. E., Swol, F. and Shelnutt, J. A. (2004) Synthesis of peptide-nanotube platinum-nanoparticle composites. Chem. Commun. 1044-1045.
-
(2004)
Chem. Commun.
, pp. 1044-1045
-
-
Song, Y.1
Challa, S.R.2
Medforth, C.J.3
Qiu, Y.4
Watt, R.K.5
Peña, D.6
Miller, J.E.7
Swol, F.8
Shelnutt, J.A.9
-
33
-
-
0037466613
-
Casting metal nanowires within discrete self-assembled peptide nanotubes
-
Reches, M. and Gazit, E. (2003) Casting metal nanowires within discrete self-assembled peptide nanotubes. Science 300, 625-627.
-
(2003)
Science
, vol.300
, pp. 625-627
-
-
Reches, M.1
Gazit, E.2
-
34
-
-
33748309346
-
Fabrication of coaxial metal nanocables using a self-assembled peptide nanotube scaffold
-
Carny, O., Shalev, D. E. and Gazit, E. (2006) Fabrication of coaxial metal nanocables using a self-assembled peptide nanotube scaffold. Nano Lett. 6, 1594-1597.
-
(2006)
Nano Lett
, vol.6
, pp. 1594-1597
-
-
Carny, O.1
Shalev, D.E.2
Gazit, E.3
-
35
-
-
0038072777
-
Asseblies of metal nanoparticles and self-assembled peptide fibrils - formation of double helical and single-chain arrays of metal nanoparticles
-
Fu, X., Wang, Y., Huang, L., Sha, Y., Gui, L., Lai, L. and Tang, Y. (2003) Asseblies of metal nanoparticles and self-assembled peptide fibrils - formation of double helical and single-chain arrays of metal nanoparticles. Adv. Mater. 15, 902-906.
-
(2003)
Adv. Mater.
, vol.15
, pp. 902-906
-
-
Fu, X.1
Wang, Y.2
Huang, L.3
Sha, Y.4
Gui, L.5
Lai, L.6
Tang, Y.7
-
36
-
-
34548164419
-
Biological and chemical decoration of peptide nanostructures via biotin-avidin interactions
-
Reches, M. and Gazit, E. (2007) Biological and chemical decoration of peptide nanostructures via biotin-avidin interactions. J. Nanosci. Nanotechnol. 7, 2239-2245.
-
(2007)
J. Nanosci. Nanotechnol.
, vol.7
, pp. 2239-2245
-
-
Reches, M.1
Gazit, E.2
-
37
-
-
0037117485
-
Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein
-
Baxa, U., Speransky, V., Steven, A. C. and Wickner, R. B. (2002) Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein. Proc. Natl. Acad. Sci. U.S.A. 99, 5253-5260.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5253-5260
-
-
Baxa, U.1
Speransky, V.2
Steven, A.C.3
Wickner, R.B.4
-
38
-
-
33644555501
-
Cytochrome display on amyloid fibrils
-
Baldwin, A. J., Bader, R., Christodoulou, J., MacPhee, C. E., Dobson, C. M. and Barker, P. D. (2006) Cytochrome display on amyloid fibrils. J. Am. Chem. Soc. 128, 2162-2163.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 2162-2163
-
-
Baldwin, A.J.1
Bader, R.2
Christodoulou, J.3
MacPhee, C.E.4
Dobson, C.M.5
Barker, P.D.6
-
39
-
-
33845213536
-
The formation of nematic liquid crystal phases by hen lysozyme amyloid fibrils
-
Corrigan, A. M., Müller, C. and Krebs, M. R. H. (2006) The formation of nematic liquid crystal phases by hen lysozyme amyloid fibrils. J. Am. Chem. Soc. 128, 14740-14741.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 14740-14741
-
-
Corrigan, A.M.1
Müller, C.2
Krebs, M.R.H.3
-
40
-
-
0030934379
-
Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes
-
Aggeli, A., Bell, M., Boden, N., Keen, J. N., Knowles, P. F., McLeish, T. C. B., Pitkeathly, M. and Radford, S. E. (1997) Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes. Nature 386, 259-262.
-
(1997)
Nature
, vol.386
, pp. 259-262
-
-
Aggeli, A.1
Bell, M.2
Boden, N.3
Keen, J.N.4
Knowles, P.F.5
McLeish, T.C.B.6
Pitkeathly, M.7
Radford, S.E.8
-
41
-
-
0242490652
-
Supramolecular hydrogels respond to lignad-receptor interaction
-
Zhang, Y., Gu, H., Yang, Z. and Xu, B. (2003) Supramolecular hydrogels respond to lignad-receptor interaction. J. Am. Chem. Soc. 125, 13680-13681.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 13680-13681
-
-
Zhang, Y.1
Gu, H.2
Yang, Z.3
Xu, B.4
-
42
-
-
33644944179
-
Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo
-
Yang, Z., Liang, G., Wang, L. and Xu, B. (2006) Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo. J. Am. Chem. Soc. 128, 3038-3043.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 3038-3043
-
-
Yang, Z.1
Liang, G.2
Wang, L.3
Xu, B.4
-
43
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant a-synuclein linked to early-onset Parkinson disease
-
Conway, K. A., Harper, J. D. and Lansbury, P. T. Jr. (1998) Accelerated in vitro fibril formation by a mutant a-synuclein linked to early-onset Parkinson disease. Nat. Med. 4, 1318-1320.
-
(1998)
Nat. Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury P.T., Jr.3
-
44
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A. and Lansbury, P. T. Jr. (1996) NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35, 13709-13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury P.T., Jr.5
-
45
-
-
0033538015
-
Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro
-
Kayed, R., Bernhagen, J., Greenfield, N., Sweimeh, K., Brunner, H., Voelter, W. and Kapurniotu, A. (1999) Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro. J. Mol. Biol. 287, 781-796.
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 781-796
-
-
Kayed, R.1
Bernhagen, J.2
Greenfield, N.3
Sweimeh, K.4
Brunner, H.5
Voelter, W.6
Kapurniotu, A.7
-
46
-
-
0032084472
-
Structural and kinetic features of amyloid b-protein fibrillogenesis
-
Teplow, D. B. (1998) Structural and kinetic features of amyloid b-protein fibrillogenesis. Amyloid: Int. J. Exp. Clin. Invest. 5, 121-142.
-
(1998)
Amyloid: Int. J. Exp. Clin. Invest.
, vol.5
, pp. 121-142
-
-
Teplow, D.B.1
-
47
-
-
0033520461
-
Amyloid β-protein fibrillogenesis
-
Walsh, D. M., Hartley, D. M., Kusumoto, Y., Fezoui, Y., Condron, M. M., Lomakin, A., Benedek, G. B., Selkoe, D. J. and Teplow, D. B. (1999) Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J. Biol. Chem. 274, 25945-25952.
-
(1999)
Structure and biological activity of protofibrillar intermediates. J. Biol. Chem.
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
Benedek, G.B.7
Selkoe, D.J.8
Teplow, D.B.9
-
48
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies form Parkinson's disease and dementia with Lewy bodies
-
Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M. and Goedert, M. (1998) α-Synuclein in filamentous inclusions of Lewy bodies form Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. U.S.A. 95, 6469-6473.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
49
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini, M. G., Schmidt, M. L., Lee, V. M. -Y., Trojanowski, J. Q., Jakes, R. and Goedert, M. (1997) α-Synuclein in Lewy bodies. Nature 388, 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.-Y.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
50
-
-
1842611727
-
a-Synuclein and Parkinson's disease
-
Recchia, A., Debetto, P., Negro, A., Guidolin, D., Skaper, S. D. and Giusti, P. (2004) a-Synuclein and Parkinson's disease. FASEB 18, 617-626.
-
(2004)
FASEB
, vol.18
, pp. 617-626
-
-
Recchia, A.1
Debetto, P.2
Negro, A.3
Guidolin, D.4
Skaper, S.D.5
Giusti, P.6
-
51
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
Goedert, M. (2001) Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2, 492-501.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
52
-
-
33749841522
-
The aggregation and fibrillation of α-synuclein
-
Fink, A. L. (2006) The aggregation and fibrillation of α-synuclein. Acc. Chem. Res. 39, 628-634.
-
(2006)
Acc. Chem. Res.
, vol.39
, pp. 628-634
-
-
Fink, A.L.1
-
53
-
-
0035969513
-
Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology
-
Jaikaran, E. T. A. S. and Clark, A. (2001) Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology. Biochim. Biophys. Acta-Mol. Basis Dis. 1537, 179-203.
-
(2001)
Biochim. Biophys. Acta-Mol. Basis Dis.
, vol.1537
, pp. 179-203
-
-
Jaikaran, E.T.A.S.1
Clark, A.2
-
54
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy, J. A. and Higgins, G. A. (1992) Alzheimer's disease: The amyloid cascade hypothesis. Science 256, 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
55
-
-
57749098600
-
Amyloid formation by globular proteins under native conditions
-
Chiti, F. and Dobson, C. M. (2009) Amyloid formation by globular proteins under native conditions. Nat. Chem. Biol. 5, 15-22.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 15-22
-
-
Chiti, F.1
Dobson, C.M.2
-
56
-
-
33646126278
-
New insights into prion structure and toxicity
-
Harris, D. A. and True, H. L. (2006) New insights into prion structure and toxicity. Neuron 50, 353-357.
-
(2006)
Neuron
, vol.50
, pp. 353-357
-
-
Harris, D.A.1
True, H.L.2
-
57
-
-
0019180741
-
b2-Microglobulin: structure, function and significance
-
Bernier, G. M. (1980) b2-Microglobulin: structure, function and significance. Vox Sanguinis. 38, 323-327.
-
(1980)
Vox Sanguinis
, vol.38
, pp. 323-327
-
-
Bernier, G.M.1
-
58
-
-
0037162520
-
Crystal structure of monomeric human β-2-microglobulin reveals clues to its amyloidogenic properties
-
Trinh, C. H., Smith, D. P., Kalverda, A. P., Phillips, S. E. V. and Radford, S. E. (2002) Crystal structure of monomeric human β-2-microglobulin reveals clues to its amyloidogenic properties. Proc. Natl. Acad. Sci. U.S.A. 99, 9771-9776.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9771-9776
-
-
Trinh, C.H.1
Smith, D.P.2
Kalverda, A.P.3
Phillips, S.E.V.4
Radford, S.E.5
-
59
-
-
0019816864
-
Refinement of human lysozyme at 1.5 Å resoution analysis of nonbonded and hydrogen-bond interactions
-
Artymiuk, P. J. and Blake, C. C. F. (1981) Refinement of human lysozyme at 1.5 Å resoution analysis of nonbonded and hydrogen-bond interactions. J. Mol. Biol. 152, 737-762.
-
(1981)
J. Mol. Biol.
, vol.152
, pp. 737-762
-
-
Artymiuk, P.J.1
Blake, C.C.F.2
-
60
-
-
0013852463
-
Structure of hen egg-white lysozyme: a three-dimensional fourier synthesis at 2 Å resolution
-
Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C. and Sarma, V. R. (1965) Structure of hen egg-white lysozyme: a three-dimensional fourier synthesis at 2 Å resolution. Nature 206, 757-761.
-
(1965)
Nature
, vol.206
, pp. 757-761
-
-
Blake, C.C.F.1
Koenig, D.F.2
Mair, G.A.3
North, A.C.T.4
Phillips, D.C.5
Sarma, V.R.6
-
61
-
-
0030830019
-
Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid
-
Kelly, J. W., Colon, W., Lai, Z., Lashuel, H. A., McCulloch, J., McCutchen, S. L., Miroy, G. J. and Peterson, S. A. (1997) Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid. Adv. Protein. Chem. 50, 161-181.
-
(1997)
Adv. Protein. Chem.
, vol.50
, pp. 161-181
-
-
Kelly, J.W.1
Colon, W.2
Lai, Z.3
Lashuel, H.A.4
McCulloch, J.5
McCutchen, S.L.6
Miroy, G.J.7
Peterson, S.A.8
-
62
-
-
0033855656
-
Review: Immunoglobulin light chain amyloidosis - The archetype of structural and pathogenic variability
-
Bellotti, V., Mangione, P. and Merlini, G. (2000) Review: Immunoglobulin light chain amyloidosis - The archetype of structural and pathogenic variability. J. Struct. Biol. 130, 280-289.
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 280-289
-
-
Bellotti, V.1
Mangione, P.2
Merlini, G.3
-
64
-
-
0026561487
-
Dialysis-related amyloidosis
-
Koch, K. M. (1992) Dialysis-related amyloidosis. Kidney Int. 41, 1416-1429.
-
(1992)
Kidney Int
, vol.41
, pp. 1416-1429
-
-
Koch, K.M.1
-
65
-
-
0027506498
-
Human lysozyme gene mutations cause hereditary systemic amyloidosis
-
Pepys, M. B., Hawkins, P. N., Booth, D. R., Vigushin, D. M., Tennent, G. A., Soutar, A. K., Totty, N., Nguyen, O., Blake, C. C. F., Terry, C. J., Feest, T. G., Zalin, A. M. and Hsuan, J. J. (1993) Human lysozyme gene mutations cause hereditary systemic amyloidosis. Nature 362, 553-557.
-
(1993)
Nature
, vol.362
, pp. 553-557
-
-
Pepys, M.B.1
Hawkins, P.N.2
Booth, D.R.3
Vigushin, D.M.4
Tennent, G.A.5
Soutar, A.K.6
Totty, N.7
Nguyen, O.8
Blake, C.C.F.9
Terry, C.J.10
Feest, T.G.11
Zalin, A.M.12
Hsuan, J.J.13
-
66
-
-
49749199032
-
Cleavage of the haem-protein link by acid methylethylketone
-
Teale, F. W. J. (1959) Cleavage of the haem-protein link by acid methylethylketone. Biochim. Biophys. Acta. 35, 543.
-
(1959)
Biochim. Biophys. Acta.
, vol.35
, pp. 543
-
-
Teale, F.W.J.1
-
67
-
-
0035826234
-
Amyloid fibrils from muscle myoglobin
-
Fändrich, M., Fletcher, M. A. and Dobson, C. M. (2001) Amyloid fibrils from muscle myoglobin. Nature 410, 165-166.
-
(2001)
Nature
, vol.410
, pp. 165-166
-
-
Fändrich, M.1
Fletcher, M.A.2
Dobson, C.M.3
-
68
-
-
0346734137
-
Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments
-
Fändrich, M., Forge, V., Buder, K., Kittler, M., Dobson, C. M. and Diekmann, S. (2003) Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments. Proc. Natl. Acad. Sci. U.S.A. 100, 15463-15468.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 15463-15468
-
-
Fändrich, M.1
Forge, V.2
Buder, K.3
Kittler, M.4
Dobson, C.M.5
Diekmann, S.6
-
69
-
-
33846160381
-
Polymorphism in the intermediates and products of amyloid assembly
-
Kodali, R. and Wetzel, R. (2007) Polymorphism in the intermediates and products of amyloid assembly. Curr. Opin. Struct. Biol. 17, 48-57.
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 48-57
-
-
Kodali, R.1
Wetzel, R.2
-
70
-
-
12244249201
-
Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
-
Petkova, A. T., Leapman, R. D., Guo, Z., Yau, W. -M., Mattson, M. P. and Tycko, R. (2005) Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils. Science 307, 262-265.
-
(2005)
Science
, vol.307
, pp. 262-265
-
-
Petkova, A.T.1
Leapman, R.D.2
Guo, Z.3
Yau, W.-M.4
Mattson, M.P.5
Tycko, R.6
-
71
-
-
33846126930
-
Plasticity of amyloid fibrils
-
Wetzel, R., Shivaprasad, S. and Williams, A. D. (2007) Plasticity of amyloid fibrils. Biochemistry 46, 1-10.
-
(2007)
Biochemistry
, vol.46
, pp. 1-10
-
-
Wetzel, R.1
Shivaprasad, S.2
Williams, A.D.3
-
72
-
-
24044507958
-
Multiple assembly pathways underlie amyloid-b fibril polymorphisms
-
Goldsbury, C., Frey, P., Olivieri, V., Aebi, U. and Müller, S. A. (2005) Multiple assembly pathways underlie amyloid-b fibril polymorphisms. J. Mol. Biol. 352, 282-298.
-
(2005)
J. Mol. Biol.
, vol.352
, pp. 282-298
-
-
Goldsbury, C.1
Frey, P.2
Olivieri, V.3
Aebi, U.4
Müller, S.A.5
-
73
-
-
23444445907
-
Competing pathways determine fibril morphology in the self-assembly of b2-microglobulin into amyloid
-
Gosal, W. S., Morten, I. J., Hewitt, E. W., Smith, D. A., Thomson, N. H. and Radford, S. E. (2005) Competing pathways determine fibril morphology in the self-assembly of b2-microglobulin into amyloid. J. Mol. Biol. 351, 850-864.
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 850-864
-
-
Gosal, W.S.1
Morten, I.J.2
Hewitt, E.W.3
Smith, D.A.4
Thomson, N.H.5
Radford, S.E.6
-
74
-
-
0014190760
-
Self-replication and scrapie
-
Griffith, J. S. (1967) Self-replication and scrapie. Nature 215, 1043-1044.
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
75
-
-
68649118065
-
Cells and prions: a license to replicate
-
Nuvolone, M., Aguzzi, A. and Heikenwalder, M. (2009) Cells and prions: a license to replicate. FEBS Lett. 583, 2674-2684.
-
(2009)
FEBS Lett
, vol.583
, pp. 2674-2684
-
-
Nuvolone, M.1
Aguzzi, A.2
Heikenwalder, M.3
-
76
-
-
59449092235
-
Amyloid fibrillar meshwork formation of ion-induced oligomeric species of Aβ40 with phthalocyanine tetrasulfonate and its toxic consequences
-
Park, J. -W., Ahn, J. S., Lee, J. -H., Bhak, G., Jung, S. and Paik, S. R. (2008) Amyloid fibrillar meshwork formation of ion-induced oligomeric species of Aβ40 with phthalocyanine tetrasulfonate and its toxic consequences. Chem. Bio. Chem. 9, 2602-2605.
-
(2008)
Chem. Bio. Chem.
, vol.9
, pp. 2602-2605
-
-
Park, J.-W.1
Ahn, J.S.2
Lee, J.-H.3
Bhak, G.4
Jung, S.5
Paik, S.R.6
-
77
-
-
0035838284
-
Multiple ligand interaction of a-synuclein produced various forms of protein aggregates in the presence of Aβ25-35, copper, and eosin
-
Kim, Y. -S., Lee, D., Lee, E. -K., Sung, J. Y., Chung, K. C., Kim, J. and Paik, S. R. (2001) Multiple ligand interaction of a-synuclein produced various forms of protein aggregates in the presence of Aβ25-35, copper, and eosin. Brain Res. 908, 93-98.
-
(2001)
Brain Res
, vol.908
, pp. 93-98
-
-
Kim, Y.-S.1
Lee, D.2
Lee, E.-K.3
Sung, J.Y.4
Chung, K.C.5
Kim, J.6
Paik S.R7
-
78
-
-
0037468467
-
-
Paik, S. R., Lee, D., Cho, H. -J., Lee, E. -N. and Chang, C. -S. (2003) Oxidized glutathione stimulated the amyloid formation of a-synuclein. FEBS Lett. 537, 63-67.
-
(2003)
FEBS Lett
, vol.537
, pp. 63-67
-
-
Paik, S.R.1
Lee, D.2
Cho, H.-J.3
Lee, E.-N.4
Chang, C.-S.5
-
79
-
-
0034826292
-
Self-oligomerization and protein aggregation of a-synuclein in the presence of coomassie brilliant blue
-
Lee, D., Lee, E. -K., Lee, J. -H., Chang, C. -S. and Paik, S. R. (2001) Self-oligomerization and protein aggregation of a-synuclein in the presence of coomassie brilliant blue. Eur. J. Biochem. 268, 295-301.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 295-301
-
-
Lee, D.1
Lee, E.-K.2
Lee, J.-H.3
Chang, C.-S.4
Paik, S.R.5
-
80
-
-
0033863798
-
Review: modulating factors in amyloi-b fibril formation
-
McLaurin, J., Yang, D. -S., Yip, C. M. and Fraser, P. E. (2000) Review: modulating factors in amyloi-b fibril formation. J. Struct. Biol. 130, 259-270.
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 259-270
-
-
McLaurin, J.1
Yang, D.-S.2
Yip, C.M.3
Fraser, P.E.4
-
81
-
-
34548065205
-
Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity
-
Dong, J., Canfield, J. M., Mehta, A. K., Shokes, J. E., Tian, B., Childers, W. S., Simmons, J. A., Mao, Z., Scott, R. A., Warncke, K. and Lynn, D. G. (2007) Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity. Proc. Natl. Acad. Sci. U.S.A. 104, 13313-13318.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 13313-13318
-
-
Dong, J.1
Canfield, J.M.2
Mehta, A.K.3
Shokes, J.E.4
Tian, B.5
Childers, W.S.6
Simmons, J.A.7
Mao, Z.8
Scott, R.A.9
Warncke, K.10
Lynn, D.G.11
-
82
-
-
0034663858
-
Accelerated accumulation of amyloid b proteins on oxidatively damaged lipid membranes
-
Koppaka, V. and Axelsen, P. H. (2000) Accelerated accumulation of amyloid b proteins on oxidatively damaged lipid membranes. Biochemistry 39, 10011-10016.
-
(2000)
Biochemistry
, vol.39
, pp. 10011-10016
-
-
Koppaka, V.1
Axelsen, P.H.2
-
83
-
-
0032855484
-
Kinetic analysis of amyloid fibril formation
-
Naiki, H. and Gejyo, F. (1999) Kinetic analysis of amyloid fibril formation. Methods Enzymol. 309, 305-318.
-
(1999)
Methods Enzymol
, vol.309
, pp. 305-318
-
-
Naiki, H.1
Gejyo, F.2
-
84
-
-
0027195933
-
Seeding "onedimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett, J. T. and Lansbury, P. T. Jr. (1993) Seeding "onedimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73, 1055-1058.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury P.T., Jr.2
-
85
-
-
0030908095
-
Models of amyloid seeding in Alzheimer's disease and scrapie: Mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins
-
Harper, J. D. and Lansbury, P. T. Jr. (1997) Models of amyloid seeding in Alzheimer's disease and scrapie: Mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. Annu. Rev. Biochem. 66, 385-407.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 385-407
-
-
Harper, J.D.1
Lansbury P.T., Jr.2
-
86
-
-
0033538541
-
α-Synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease
-
Wood, S. J., Wypych, J., Steavenson, S., Louis, J. -C., Citron, M. and Biere, A. L. (1999) α-Synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease. J. Biol. Chem. 274, 509-512.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 509-512
-
-
Wood, S.J.1
Wypych, J.2
Steavenson, S.3
Louis, J.-C.4
Citron, M.5
Biere, A.L.6
-
87
-
-
38949139507
-
Conformational equilibria in monomeric α-synuclein at the single-molecule level
-
Sandal, M., Valle, F., Tessari, I., Mammi, S., Bergantino, E., Musiani, F., Brucale, M., Bubacco, L. and Samori, B. (2008) Conformational equilibria in monomeric α-synuclein at the single-molecule level. PLoS Biol. 6, e6.
-
(2008)
PLoS Biol
, vol.6
-
-
Sandal, M.1
Valle, F.2
Tessari, I.3
Mammi, S.4
Bergantino, E.5
Musiani, F.6
Brucale, M.7
Bubacco, L.8
Samori, B.9
-
88
-
-
0035941305
-
Stabilization of partially folded conformation during a-synuclein oligomerization in both purified and cytosolic preparations
-
Uversky, V. N., Lee, H. -J., Li, J., Fink, A. L. and Lee, S. -J. (2001) Stabilization of partially folded conformation during a-synuclein oligomerization in both purified and cytosolic preparations. J. Biol. Chem. 276, 43495-43498.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43495-43498
-
-
Uversky, V.N.1
Lee, H.-J.2
Li, J.3
Fink, A.L.4
Lee, S.-J.5
-
89
-
-
0028865843
-
3D domain swapping: a mechanism for oligomer assembly
-
Bennett, M. J., Schlunegger, M. P. and Eisenberg, D. (1995) 3D domain swapping: a mechanism for oligomer assembly. Protein Sci. 4, 2455-2468.
-
(1995)
Protein Sci
, vol.4
, pp. 2455-2468
-
-
Bennett, M.J.1
Schlunegger, M.P.2
Eisenberg, D.3
-
90
-
-
0034714351
-
Nucleated conformational conversion and the replication of conformational information by a prion determinant
-
Serio, T. R., Cashikar, A. G., Kowal, A. S., Sawicki, G. J., Moslehi, J. J., Serpell, L., Arnsdorf, M. F. and Lindquist, S. L. (2000) Nucleated conformational conversion and the replication of conformational information by a prion determinant. Science 289, 1317-1321.
-
(2000)
Science
, vol.289
, pp. 1317-1321
-
-
Serio, T.R.1
Cashikar, A.G.2
Kowal, A.S.3
Sawicki, G.J.4
Moslehi, J.J.5
Serpell, L.6
Arnsdorf, M.F.7
Lindquist, S.L.8
-
91
-
-
0035949542
-
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein
-
Li, J., Uversky, V. N. and Fink, A. L. (2001) Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein. Biochemistry 40, 604-613.
-
(2001)
Biochemistry
, vol.40
, pp. 604-613
-
-
Li, J.1
Uversky, V.N.2
Fink, A.L.3
-
92
-
-
0035815664
-
Evidence for a partially folded intermediate in α-synuclein fibril formation
-
Uversky, V. N., Li, J. and Fink, A. L. (2001) Evidence for a partially folded intermediate in α-synuclein fibril formation. J. Biol. Chem. 276, 10737-10744.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10737-10744
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
93
-
-
0035816404
-
Pesticides directly accelerate the rate of α-synuclein fibril formation: a possible factor in Parkinson's disease
-
Uversky, V. N., Li, J. and Fink, A. L. (2001) Pesticides directly accelerate the rate of α-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett. 500, 105-108.
-
(2001)
FEBS Lett
, vol.500
, pp. 105-108
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
94
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure
-
Uversky, V. N., Li, J. and Fink, A. L. (2001) Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. J. Biol. Chem. 276, 44284-44296.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
95
-
-
23144459082
-
Molecular recycling within amyloid fibrils
-
Carulla, N., Caddy, G. L., Hall, D. R., Zurdo, J., Gairi, M., Feliz, M., Giralt, E., Robinson, C. V. and Dobson, C. M. (2005) Molecular recycling within amyloid fibrils. Nature 436, 554-558.
-
(2005)
Nature
, vol.436
, pp. 554-558
-
-
Carulla, N.1
Caddy, G.L.2
Hall, D.R.3
Zurdo, J.4
Gairi, M.5
Feliz, M.6
Giralt, E.7
Robinson, C.V.8
Dobson, C.M.9
-
96
-
-
28844441969
-
Secondary structure of a-synuclein oligomers: characterization by Raman and atomic force microscopy
-
Apetri, M. M., Maiti, N. C., Zagorski, M. G., Carey, P. R. and Anderson, V. E. (2006) Secondary structure of a-synuclein oligomers: characterization by Raman and atomic force microscopy. J. Mol. Biol. 355, 63-71.
-
(2006)
J. Mol. Biol.
, vol.355
, pp. 63-71
-
-
Apetri, M.M.1
Maiti, N.C.2
Zagorski, M.G.3
Carey, P.R.4
Anderson, V.E.5
-
97
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both a-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy
-
Conway, K. A., Lee, S. -J., Rochet, J. -C., Ding, T. T., Williamson, R. E. and Lansbury, P. T. Jr. (2000) Acceleration of oligomerization, not fibrillization, is a shared property of both a-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc. Natl. Acad. Sci. U.S.A. 97, 571-576.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.-J.2
Rochet, J.-C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury P.T., Jr.6
-
98
-
-
0037072284
-
Annular a-synuclein protofibrils are produced when spherical protofibrils are incubated in solution of bound to brain-derived membranes
-
Ding, T. T., Lee, S. -J., Rochet, J. -C. and Lansbury, P. T. Jr. (2002) Annular a-synuclein protofibrils are produced when spherical protofibrils are incubated in solution of bound to brain-derived membranes. Biochemistry 41, 10209-10217.
-
(2002)
Biochemistry
, vol.41
, pp. 10209-10217
-
-
Ding, T.T.1
Lee, S.-J.2
Rochet, J.-C.3
Lansbury P.T., Jr.4
-
99
-
-
2942592408
-
Rapid self-assembly of a-synuclein observed by in situ atomic force microscopy
-
Hoyer, W., Cherny, D., Subramaniam, V. and Jovin, T. M. (2004) Rapid self-assembly of a-synuclein observed by in situ atomic force microscopy. J. Mol. Biol. 340, 127-139.
-
(2004)
J. Mol. Biol.
, vol.340
, pp. 127-139
-
-
Hoyer, W.1
Cherny, D.2
Subramaniam, V.3
Jovin, T.M.4
-
100
-
-
0037422540
-
Amyloid b-protein (Ab) assembly: Ab40 and Ab42 oligomerize through distinct pathways
-
Bitan, G., Kirkitadze, M. D., Lomakin, A., Vollers, S. S., Benedek, G. B. and Teplow, D. B. (2003) Amyloid b-protein (Ab) assembly: Ab40 and Ab42 oligomerize through distinct pathways. Proc. Natl. Acad. Sci. U.S.A. 100, 330-335.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 330-335
-
-
Bitan, G.1
Kirkitadze, M.D.2
Lomakin, A.3
Vollers, S.S.4
Benedek, G.B.5
Teplow, D.B.6
-
101
-
-
51349098137
-
Evidence for stepwise formation of amyloid fibrils by the mouse prion protein
-
Jain, S. and Udgaonkar, J. B. (2008) Evidence for stepwise formation of amyloid fibrils by the mouse prion protein. J. Mol. Biol. 382, 1228-1241.
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 1228-1241
-
-
Jain, S.1
Udgaonkar, J.B.2
-
102
-
-
2942748436
-
Oligomeric assembly of native-like precursors precedes amyloid formation by β-2 microglobulin
-
Eakin, C. M., Attenello, F. J., Morgan, C. J. and Miranker, A. D. (2004) Oligomeric assembly of native-like precursors precedes amyloid formation by β-2 microglobulin. Biochemistry 43, 7808-7815.
-
(2004)
Biochemistry
, vol.43
, pp. 7808-7815
-
-
Eakin, C.M.1
Attenello, F.J.2
Morgan, C.J.3
Miranker, A.D.4
-
103
-
-
0037255361
-
Assembly of amyloid protofibrils via critical oligomers - A novel pathway of amyloid formation
-
Modler, A. J., Gast, K., Lutsch, G. and Damaschun, G. (2003) Assembly of amyloid protofibrils via critical oligomers - A novel pathway of amyloid formation. J. Mol. Biol. 325, 135-148.
-
(2003)
J. Mol. Biol.
, vol.325
, pp. 135-148
-
-
Modler, A.J.1
Gast, K.2
Lutsch, G.3
Damaschun, G.4
-
104
-
-
48949106204
-
Kinetics of fibril formation of bovine k-casein indicate a conformational rearrangement as a critical step in the process
-
Leonil, J., Henry, G., Jouanneau, D., Delage, M. -M., Forge, V. and Putaux, J. -L. (2008) Kinetics of fibril formation of bovine k-casein indicate a conformational rearrangement as a critical step in the process. J. Mol. Biol. 381, 1267-1280.
-
(2008)
J. Mol. Biol.
, vol.381
, pp. 1267-1280
-
-
Leonil, J.1
Henry, G.2
Jouanneau, D.3
Delage, M.-M.4
Forge, V.5
Putaux, J.-L.6
-
105
-
-
34848929022
-
Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils
-
Cheon, M., Chang, I., Mohanty, S., Luheshi, L. M., Dobson, C. M., Vendruscolo, M. and Favrin, G. (2007) Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils. PLoS Comput. Biol. 3, 1727-1738.
-
(2007)
PLoS Comput. Biol.
, vol.3
, pp. 1727-1738
-
-
Cheon, M.1
Chang, I.2
Mohanty, S.3
Luheshi, L.M.4
Dobson, C.M.5
Vendruscolo, M.6
Favrin, G.7
-
106
-
-
58649100263
-
Granular assembly of a-synuclein leading to the accelerated amyloid fibril formation with shear stress
-
Bhak, G., Lee, J. -H., Hahn, J. -S. and Paik, S. R. (2009) Granular assembly of a-synuclein leading to the accelerated amyloid fibril formation with shear stress. PLoS ONE 4, e4177.
-
(2009)
PLoS ONE
, vol.4
-
-
Bhak, G.1
Lee, J.-H.2
Hahn, J.-S.3
Paik, S.R.4
-
107
-
-
47749146102
-
Instantaneous amyloid fibril formation of a-synuclein from the oligomeric granular structures in the presence of hexane
-
Lee, J. -H., Bhak, G., Lee, S. -G. and Paik, S. R. (2008) Instantaneous amyloid fibril formation of a-synuclein from the oligomeric granular structures in the presence of hexane. Biophys. J. 95, L16-L18.
-
(2008)
Biophys. J.
, vol.95
-
-
Lee, J.-H.1
Bhak, G.2
Lee, S.3
Paik, S.R.4
-
108
-
-
34249028643
-
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils
-
Vestergaard, B., Groenning, M., Roessle, M., Kastrup, J. S., Weert, M., Flink, J. M., Frokjaer, S., Gajhede, M. and Svergun, D. I. (2007) A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils. PLoS Biol. 5, e134.
-
(2007)
PLoS Biol
, vol.5
-
-
Vestergaard, B.1
Groenning, M.2
Roessle, M.3
Kastrup, J.S.4
Weert, M.5
Flink, J.M.6
Frokjaer, S.7
Gajhede, M.8
Svergun, D.I.9
-
109
-
-
0038701684
-
Huntingtin aggregation and toxicity in Huntington's disease
-
Bates, G. (2003) Huntingtin aggregation and toxicity in Huntington's disease. Lancet 361, 1642-1644.
-
(2003)
Lancet
, vol.361
, pp. 1642-1644
-
-
Bates, G.1
-
110
-
-
3342906956
-
Fibrillation of carrier protein albebetin and its biologically active constructs. Multiple oligomeric intermediates and pathways
-
Morozova-Roche, L. A., Zamotin, V., Malisauskas, M., Öhman, A., Chertkova, R., Lavrikova, M. A., Kostanyan, I. A., Dolgikh, D. A. and Kirpichnikov, M. P. (2004) Fibrillation of carrier protein albebetin and its biologically active constructs. Multiple oligomeric intermediates and pathways. Biochemistry 43, 9610-9619.
-
(2004)
Biochemistry
, vol.43
, pp. 9610-9619
-
-
Morozova-Roche, L.A.1
Zamotin, V.2
Malisauskas, M.3
Öhman, A.4
Chertkova, R.5
Lavrikova, M.A.6
Kostanyan, I.A.7
Dolgikh, D.A.8
Kirpichnikov, M.P.9
-
111
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W. and Glabe, C. G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
112
-
-
25444433798
-
Characterization of oligomeric intermediates in a-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F α-synuclein
-
Kaylor, J., Bodner, N., Edridge, S., Yamin, G., Hong, D. -P. and Fink, A. L. (2005) Characterization of oligomeric intermediates in a-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F α-synuclein. J. Mol. Biol. 353, 357-372.
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 357-372
-
-
Kaylor, J.1
Bodner, N.2
Edridge, S.3
Yamin, G.4
Hong, D.-P.5
Fink, A.L.6
-
113
-
-
58149400915
-
Conformational conversion may precede or follow aggregate elongation on alternative pathways of amyloid protofibril formation
-
Kumar, S. and Udgaonkar, J. B. (2009) Conformational conversion may precede or follow aggregate elongation on alternative pathways of amyloid protofibril formation. J. Mol. Biol. 385, 1266-1276.
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 1266-1276
-
-
Kumar, S.1
Udgaonkar, J.B.2
-
114
-
-
8744220663
-
Permeabilization of lipid bilayers is a common conformationdependent activity of soluble amyloid oligomers in protein misfolding diseases
-
Kayed, R., Sokolov, Y., Edmonds, B., McIntire, T. M., Milton, S. C., Hall, J. E. and Glabe, C. G. (2004) Permeabilization of lipid bilayers is a common conformationdependent activity of soluble amyloid oligomers in protein misfolding diseases. J. Biol. Chem. 279, 46363-46366.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46363-46366
-
-
Kayed, R.1
Sokolov, Y.2
Edmonds, B.3
McIntire, T.M.4
Milton, S.C.5
Hall, J.E.6
Glabe, C.G.7
-
115
-
-
0038047044
-
Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN
-
Souillac, P. O., Uversky, V. N. and Fink, A. L. (2003) Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN. Biochemistry 42, 8094-8104.
-
(2003)
Biochemistry
, vol.42
, pp. 8094-8104
-
-
Souillac, P.O.1
Uversky, V.N.2
Fink, A.L.3
-
116
-
-
30344457011
-
Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation
-
Bader, R., Bamford, R., Zurdo, J., Luisi, B. F. and Dobson, C. M. (2006) Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation. J. Mol. Biol. 356, 189-208.
-
(2006)
J. Mol. Biol.
, vol.356
, pp. 189-208
-
-
Bader, R.1
Bamford, R.2
Zurdo, J.3
Luisi, B.F.4
Dobson, C.M.5
-
117
-
-
0035920156
-
Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants
-
Quintas, A., Vaz, D. C., Cardoso, I., Saraiva, M. J. M. and Brito, R. M. M. (2001) Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants. J. Biol. Chem. 276, 27207-27213.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27207-27213
-
-
Quintas, A.1
Vaz, D.C.2
Cardoso, I.3
Saraiva, M.J.M.4
Brito, R.M.M.5
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