Tetramer Dissociation and Monomer Partial Unfolding Precedes Protofibril Formation in Amyloidogenic Transthyretin Variants

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 27207-27213

  Quintas, Alexandre ^a,b   Vaz, Daniela C ^a   Cardoso, Isabel ^c   Saraiva, Maria João M ^c   Brito, Rui M M ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; CONFORMATIONS; DISEASE CONTROL; DISSOCIATION; MONOMERS; PROTEINS; SOLUBILITY;

FIBRILS; TETRAMERS;

BIOCHEMISTRY;

AMYLOID; PREALBUMIN; TETRAMER; THIOFLAVINE; BIOPOLYMER; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; AMYLOIDOSIS; ARTICLE; BRAIN SPONGIOSIS; DISSOCIATION; FAMILIAL AMYLOID POLYNEUROPATHY; IONIC STRENGTH; MOLECULAR WEIGHT; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; THERMODYNAMICS; BIOSYNTHESIS; CHEMISTRY; ELECTRON MICROSCOPY; GEL CHROMATOGRAPHY; PROTEIN DENATURATION; ULTRASTRUCTURE;

AMYLOID; BIOPOLYMERS; CHROMATOGRAPHY, GEL; MICROSCOPY, ELECTRON; PREALBUMIN; PROTEIN CONFORMATION; PROTEIN DENATURATION; RECOMBINANT PROTEINS;

EID: 0035920156     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101024200     Document Type: Article

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