메뉴 건너뛰기




Volumn 85, Issue 11, 2009, Pages 989-1001

Impact of exogenous lactate on survival and radioresponse of carcinoma cells in vitro

Author keywords

Acidosis; Cell survival; Irradiation; Lactate; MCT1; Radioresponse; Tumour pathophysiology

Indexed keywords

CD147 ANTIGEN; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1;

EID: 70449507024     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553000903242156     Document Type: Article
Times cited : (16)

References (52)
  • 5
    • 33749987728 scopus 로고    scopus 로고
    • The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells
    • Cheeti S, Warrier BK, Lee CH. 2006. The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells. International Journal of Pharmaceutics 325:48-54.
    • (2006) International Journal of Pharmaceutics , vol.325 , pp. 48-54
    • Cheeti, S.1    Warrier, B.K.2    Lee, C.H.3
  • 6
    • 33747505788 scopus 로고    scopus 로고
    • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis
    • Chesney J. 2006. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis. Current Opinion in Clinical Nutrition and Metabolic Care 9:535-539.
    • (2006) Current Opinion in Clinical Nutrition and Metabolic Care , vol.9 , pp. 535-539
    • Chesney, J.1
  • 8
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Broer S. 2000. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochemical Journal 350Pt 1:219-227.
    • (2000) Biochemical Journal , vol.350 , Issue.PART 1 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Broer, S.5
  • 11
    • 34447258681 scopus 로고    scopus 로고
    • Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
    • Fukumura D, Jain RK. 2007. Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize. Journal of Cellular Biochemistry 101:937-949.
    • (2007) Journal of Cellular Biochemistry , vol.101 , pp. 937-949
    • Fukumura, D.1    Jain, R.K.2
  • 13
    • 57749111596 scopus 로고    scopus 로고
    • Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
    • Ganapathy V, Thangaraju M, Prasad PD. 2009. Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond. Pharmacology & Therapeutics 121:29-40.
    • (2009) Pharmacology & Therapeutics , vol.121 , pp. 29-40
    • Ganapathy, V.1    Thangaraju, M.2    Prasad, P.D.3
  • 15
    • 0035899332 scopus 로고    scopus 로고
    • Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
    • Gayet J, Zhou XP, Duval A, Rolland S, Hoang JM, Cottu P, Hamelin R. 2001. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene 20:5025-5032.
    • (2001) Oncogene , vol.20 , pp. 5025-5032
    • Gayet, J.1    Zhou, X.P.2    Duval, A.3    Rolland, S.4    Hoang, J.M.5    Cottu, P.6    Hamelin, R.7
  • 16
    • 33645707133 scopus 로고    scopus 로고
    • Brave little world: Spheroids as an in vitro model to study tumor-immune-cell interactions
    • Gottfried E, Kunz-Schughart LA, Andreesen R, Kreutz M. 2006. Brave little world: Spheroids as an in vitro model to study tumor-immune-cell interactions. Cell Cycle 5:691-695.
    • (2006) Cell Cycle , vol.5 , pp. 691-695
    • Gottfried, E.1    Kunz-Schughart, L.A.2    Andreesen, R.3    Kreutz, M.4
  • 18
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family - From monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Archiv
    • Halestrap AP, Meredith D. 2004. The SLC16 gene family - from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Archiv. European Journal of Physiology 447:619-628.
    • (2004) European Journal of Physiology , vol.447 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 19
    • 0033569442 scopus 로고    scopus 로고
    • The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
    • Halestrap AP, Price NT. 1999. The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation. Biochemical Journal 343 Pt 2:281-299.
    • (1999) Biochemical Journal , vol.343 , Issue.PART 2 , pp. 281-299
    • Halestrap, A.P.1    Price, N.T.2
  • 20
    • 0036554644 scopus 로고    scopus 로고
    • Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
    • Helmlinger G, Sckell A, Dellian M, Forbes NS, Jain RK. 2002. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clinical Cancer Research 8:1284-1291.
    • (2002) Clinical Cancer Research , vol.8 , pp. 1284-1291
    • Helmlinger, G.1    Sckell, A.2    Dellian, M.3    Forbes, N.S.4    Jain, R.K.5
  • 21
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Hockel M, Vaupel P. 2001. Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects. Journal of the National Cancer Institute 93:266-276.
    • (2001) Journal of the National Cancer Institute , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 22
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • Hsu PP, Sabatini DM. 2008. Cancer cell metabolism: Warburg and beyond. Cell 134:703-707.
    • (2008) Cell , vol.134 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 23
    • 0034254638 scopus 로고    scopus 로고
    • CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
    • Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN, Halestrap, AP. 2000. CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO Journal 19:3896-3904.
    • (2000) EMBO Journal , vol.19 , pp. 3896-3904
    • Kirk, P.1    Wilson, M.C.2    Heddle, C.3    Brown, M.H.4    Barclay, A.N.5    Halestrap, A.P.6
  • 25
    • 31544445490 scopus 로고    scopus 로고
    • Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma
    • Koukourakis MI, Giatromanolaki A, Harris AL, Sivridis E. 2006. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma. Cancer Research 66:632-637.
    • (2006) Cancer Research , vol.66 , pp. 632-637
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Harris, A.L.3    Sivridis, E.4
  • 30
    • 0035909527 scopus 로고    scopus 로고
    • Metabolic cooperation between different oncogenes during cell transformation: Interaction between activated ras and HPV-16 E7
    • Mazurek S, Zwerschke W, Jansen-Durr P, Eigenbrodt E. 2001. Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7. Oncogene 20:6891-6898.
    • (2001) Oncogene , vol.20 , pp. 6891-6898
    • Mazurek, S.1    Zwerschke, W.2    Jansen-Durr, P.3    Eigenbrodt, E.4
  • 41
    • 28444475478 scopus 로고    scopus 로고
    • Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway
    • Toulany M, Dittmann K, Kruger M, Baumann M, Rodemann HP. 2005. Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway. Radiotherapy and Oncology 76:143-150.
    • (2005) Radiotherapy and Oncology , vol.76 , pp. 143-150
    • Toulany, M.1    Dittmann, K.2    Kruger, M.3    Baumann, M.4    Rodemann, H.P.5
  • 42
    • 33646917296 scopus 로고    scopus 로고
    • The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism
    • Ullah MS, Davies AJ, Halestrap AP. 2006. The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. Journal of Biological Chemistry 281:9030-9037.
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 9030-9037
    • Ullah, M.S.1    Davies, A.J.2    Halestrap, A.P.3
  • 43
    • 3142587028 scopus 로고    scopus 로고
    • Tumor microenvironmental physiology and its implications for radiation oncology
    • Vaupel P. 2004. Tumor microenvironmental physiology and its implications for radiation oncology. Seminars in Radiation Oncology 14:198-206.
    • (2004) Seminars in Radiation Oncology , vol.14 , pp. 198-206
    • Vaupel, P.1
  • 44
    • 0035677961 scopus 로고    scopus 로고
    • Treatment resistance of solid tumors: Role of hypoxia and anemia
    • Vaupel P, Thews O, Hoeckel M. 2001. Treatment resistance of solid tumors: Role of hypoxia and anemia. Medical Oncology 18:243-259.
    • (2001) Medical Oncology , vol.18 , pp. 243-259
    • Vaupel, P.1    Thews, O.2    Hoeckel, M.3
  • 48
    • 3242798360 scopus 로고    scopus 로고
    • Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology
    • Walenta S, Schroeder T, Mueller-Klieser W. 2004. Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology. Current Medicinal Chemistry 11:2195-2204.
    • (2004) Current Medicinal Chemistry , vol.11 , pp. 2195-2204
    • Walenta, S.1    Schroeder, T.2    Mueller-Klieser, W.3
  • 49
    • 0036479231 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ
    • Wilson MC, Meredith D, Halestrap AP. 2002. Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ. Journal of Biological Chemistry 277:3666-3672.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 3666-3672
    • Wilson, M.C.1    Meredith, D.2    Halestrap, A.P.3
  • 50
    • 34250314555 scopus 로고    scopus 로고
    • Pre-treatment number of clonogenic cells and their radiosensitivity are major determinants of local tumour control after fractionated irradiation
    • Yaromina A, Krause M, Thames H, Rosner A, Krause M, Hessel F, Grenman R, Zips D, Baumann M. 2007. Pre-treatment number of clonogenic cells and their radiosensitivity are major determinants of local tumour control after fractionated irradiation. Radiotherapy and Oncology 83:304-310.
    • (2007) Radiotherapy and Oncology , vol.83 , pp. 304-310
    • Yaromina, A.1    Krause, M.2    Thames, H.3    Rosner, A.4    Krause, M.5    Hessel, F.6    Grenman, R.7    Zips, D.8    Baumann, M.9
  • 52
    • 58149136865 scopus 로고    scopus 로고
    • Roles of p53, MYC and HIF-1 in regulating glycolysis - The seventh hallmark of cancer
    • Yeung SJ, Pan J, Lee MH. 2008. Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer. Cellular and Molecular Life Sciences 65:3981-3999.
    • (2008) Cellular and Molecular Life Sciences , vol.65 , pp. 3981-3999
    • Yeung, S.J.1    Pan, J.2    Lee, M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.