Apoptotic signaling activated by modulation of the F0F 1-ATPase: Implications for selective killing of autoimmune lymphocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 2, 2009, Pages 437-444

  Sundberg, Thomas B ^a   Swenson, Lara ^a   Wahl, Daniel R ^a   Opipari Jr , Anthony W ^b   Glick, Gary D ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLORO 5 (4 HYDROXYPHENYL) 1 METHYL 3 (NAPTHALEN 2 YLMETYL) 4,5, DIHYDRO 1 BENZO[B][1,4]DIAZEPIN 2(3H)ONE; BENZODIAZEPINE DERIVATIVE; BZ 423; FAS ANTIGEN; PROTEIN BAK; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN NOXA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA CELL LINE; LYMPHOCYTE; MEMBRANE PERMEABILITY; MITOCHONDRION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; AUTOIMMUNITY; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BENZODIAZEPINES; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL SURVIVAL; DNA; HUMANS; JURKAT CELLS; LYMPHOCYTES; MAP KINASE KINASE 4; MICE; MICROSCOPY, FLUORESCENCE; ONCOGENE PROTEIN V-AKT; PROTON-TRANSLOCATING ATPASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 70350469988     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.156422     Document Type: Article

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