Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax

Biochemical Pharmacology

Volumn 78, Issue 8, 2009, Pages 966-973

  Blatt, Neal B ^a   Boitano, Anthony E ^a   Lyssiotis, Costas A ^a   Opipari Jr , Anthony W ^b   Glick, Gary D ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Bak; Bax; Benzodiazepine; Mcl 1; Superoxide

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BH3 PROTEIN; BIM PROTEIN; BZ 423; CYTOCHROME C; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN MCL 1; PUMA PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; BURKITT LYMPHOMA; CANCER CELL CULTURE; CELL DEATH; CELL TYPE; CONTROLLED STUDY; DRUG MECHANISM; FIBROBLAST; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; OUTER MEMBRANE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

APOPTOSIS; AVIDIN; B-LYMPHOCYTES; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BENZODIAZEPINES; BIOTINYLATION; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; COLORING AGENTS; ELECTROPORATION; FLUORESCEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MEMBRANE POTENTIALS; PROPIDIUM; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 69349101481     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.05.025     Document Type: Article

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