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Volumn 60, Issue 1, 2009, Pages 207-218

Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GENOMIC DNA; INTERLEUKIN 10; LIGAND; TRANSCRIPTION FACTOR RUNX1;

EID: 58249094864     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24227     Document Type: Article
Times cited : (103)

References (40)
  • 1
    • 18744375165 scopus 로고    scopus 로고
    • T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens
    • Datta SK, Zhang L, Xu L. T-helper cell intrinsic defects in lupus that break peripheral tolerance to nuclear autoantigens. J Mol Med 2005;83:267-78.
    • (2005) J Mol Med , vol.83 , pp. 267-278
    • Datta, S.K.1    Zhang, L.2    Xu, L.3
  • 2
    • 6044259760 scopus 로고    scopus 로고
    • T cells in the pathogenesis of systemic lupus erythematosus
    • Hoffman RW. T cells in the pathogenesis of systemic lupus erythematosus. Clin Immunol 2004;113:4-13.
    • (2004) Clin Immunol , vol.113 , pp. 4-13
    • Hoffman, R.W.1
  • 4
    • 2442461055 scopus 로고    scopus 로고
    • The roles of the new negative T cell costimulatory pathways in regulating autoimmunity
    • Khoury SJ, Sayegh MH. The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. Immunity 2004;20:529-38.
    • (2004) Immunity , vol.20 , pp. 529-538
    • Khoury, S.J.1    Sayegh, M.H.2
  • 5
    • 33745736420 scopus 로고    scopus 로고
    • T-cell tolerance or function is determined by combinatorial costimulatory signals
    • Nurieva R, Thomas S, Nguyen T, Martin-Orozco N, Wang Y, Kaja MK, et al. T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J 2006;25:2623-33.
    • (2006) EMBO J , vol.25 , pp. 2623-2633
    • Nurieva, R.1    Thomas, S.2    Nguyen, T.3    Martin-Orozco, N.4    Wang, Y.5    Kaja, M.K.6
  • 6
    • 16244389649 scopus 로고    scopus 로고
    • The B7/CD28 costimulatory family in autoimmunity
    • Keir ME, Sharpe AH. The B7/CD28 costimulatory family in autoimmunity. Immunol Rev 2005;204:128-43.
    • (2005) Immunol Rev , vol.204 , pp. 128-143
    • Keir, M.E.1    Sharpe, A.H.2
  • 7
    • 33645863160 scopus 로고    scopus 로고
    • The PD-1-PD-L pathway in immunological tolerance
    • Okazaki T, Honjo T. The PD-1-PD-L pathway in immunological tolerance. Trends Immunol 2006;27:195-201.
    • (2006) Trends Immunol , vol.27 , pp. 195-201
    • Okazaki, T.1    Honjo, T.2
  • 9
    • 4444317516 scopus 로고    scopus 로고
    • PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ
    • Sheppard KA, Fitz LJ, Lee JM, Benander C, George JA, Wooters J, et al. PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ. FEBS Lett 2004;574:37-41.
    • (2004) FEBS Lett , vol.574 , pp. 37-41
    • Sheppard, K.A.1    Fitz, L.J.2    Lee, J.M.3    Benander, C.4    George, J.A.5    Wooters, J.6
  • 13
    • 0028867420 scopus 로고
    • Loss of CTLA-4 results in massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 results in massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995;3:541-7.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 15
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
    • Prokunina L, Castillejo-Lopez C, Oberg F, Gunnarsson I, Berg L, Magnusson V, et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 2002;32:666-9.
    • (2002) Nat Genet , vol.32 , pp. 666-669
    • Prokunina, L.1    Castillejo-Lopez, C.2    Oberg, F.3    Gunnarsson, I.4    Berg, L.5    Magnusson, V.6
  • 16
    • 17044421246 scopus 로고    scopus 로고
    • Recent findings on genes associated with inflammatory disease
    • Yamada R, Ymamoto K. Recent findings on genes associated with inflammatory disease. Mutat Res 2005;573:136-51.
    • (2005) Mutat Res , vol.573 , pp. 136-151
    • Yamada, R.1    Ymamoto, K.2
  • 17
    • 21844451620 scopus 로고    scopus 로고
    • A PD-1 polymorphism is associated with disease progression in multiple sclerosis
    • Kroner A, Mehling M, Hemmer B, Rieckmann P, Toyka KV, Maurer M, et al. A PD-1 polymorphism is associated with disease progression in multiple sclerosis. Ann Neurol 2005;58:50-7.
    • (2005) Ann Neurol , vol.58 , pp. 50-57
    • Kroner, A.1    Mehling, M.2    Hemmer, B.3    Rieckmann, P.4    Toyka, K.V.5    Maurer, M.6
  • 18
    • 1542343979 scopus 로고    scopus 로고
    • Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus
    • Lin SC, Yen JH, Tsai JJ, Tsai WC, Ou TT, Liu HW, et al. Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus. Arthritis Rheum 2004;50:770-5.
    • (2004) Arthritis Rheum , vol.50 , pp. 770-775
    • Lin, S.C.1    Yen, J.H.2    Tsai, J.J.3    Tsai, W.C.4    Ou, T.T.5    Liu, H.W.6
  • 21
    • 0026777352 scopus 로고
    • Derivation of the SLEDAI: A disease activity index for lupus patients
    • and the Committee on Prognosis Studies in SLE
    • Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH, and the Committee on Prognosis Studies in SLE. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 1992;35:630-40.
    • (1992) Arthritis Rheum , vol.35 , pp. 630-640
    • Bombardier, C.1    Gladman, D.D.2    Urowitz, M.B.3    Caron, D.4    Chang, C.H.5
  • 22
    • 0036681814 scopus 로고    scopus 로고
    • T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells
    • Chernysheva AD, Kirou KA, Crow MK. T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. J Immunol 2002;169:1241-50.
    • (2002) J Immunol , vol.169 , pp. 1241-1250
    • Chernysheva, A.D.1    Kirou, K.A.2    Crow, M.K.3
  • 24
    • 34249997791 scopus 로고    scopus 로고
    • Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort
    • Thorburn CM, Prokunina-Olsson L, Sterba KA, Lum RF, Seldin MF, Alarcon-Riquelme ME, et al. Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort. Genes Immun 2007;8:279-87.
    • (2007) Genes Immun , vol.8 , pp. 279-287
    • Thorburn, C.M.1    Prokunina-Olsson, L.2    Sterba, K.A.3    Lum, R.F.4    Seldin, M.F.5    Alarcon-Riquelme, M.E.6
  • 25
    • 21544436852 scopus 로고    scopus 로고
    • Ethnic differences in allele frequency of autoimmune-disease-associated SNPs
    • Mori M, Yamada R, Kobayashi K, Kawaida R, Yamamoto K. Ethnic differences in allele frequency of autoimmune-disease-associated SNPs. J Hum Genet 2005;50:264-6.
    • (2005) J Hum Genet , vol.50 , pp. 264-266
    • Mori, M.1    Yamada, R.2    Kobayashi, K.3    Kawaida, R.4    Yamamoto, K.5
  • 26
    • 29744462591 scopus 로고    scopus 로고
    • PD-L2: PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion
    • Saunders PA, Hendrycks VR, Lidinsky WA, Woods ML. PD-L2: PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion. Eur J Immunol 2005;35:3561-9.
    • (2005) Eur J Immunol , vol.35 , pp. 3561-3569
    • Saunders, P.A.1    Hendrycks, V.R.2    Lidinsky, W.A.3    Woods, M.L.4
  • 27
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
    • Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007;8:239-45.
    • (2007) Nat Immunol , vol.8 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 28
    • 34347389213 scopus 로고    scopus 로고
    • Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells
    • Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, et al. Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood 2007;110:186-92.
    • (2007) Blood , vol.110 , pp. 186-192
    • Goldberg, M.V.1    Maris, C.H.2    Hipkiss, E.L.3    Flies, A.S.4    Zhen, L.5    Tuder, R.M.6
  • 29
    • 0042971553 scopus 로고    scopus 로고
    • Studies of autologous T cell activation in the Kunkel laboratory
    • Crow MK. Studies of autologous T cell activation in the Kunkel laboratory. Lupus 2003;12:163-9.
    • (2003) Lupus , vol.12 , pp. 163-169
    • Crow, M.K.1
  • 30
    • 0036435703 scopus 로고    scopus 로고
    • Human autologous mixed lymphocyte reaction as an in vitro model for autoreactivity to apoptotic antigens
    • Amel Kashipaz MR, Huggins ML, Powell RJ, Todd I. Human autologous mixed lymphocyte reaction as an in vitro model for autoreactivity to apoptotic antigens. Immunology 2002;107:358-65.
    • (2002) Immunology , vol.107 , pp. 358-365
    • Amel Kashipaz, M.R.1    Huggins, M.L.2    Powell, R.J.3    Todd, I.4
  • 31
    • 4344568511 scopus 로고    scopus 로고
    • Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger
    • Zhong X, Bai C, Gao W, Strom TB, Rothstein TL. Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. Int Immunol 2004;16:1181-8.
    • (2004) Int Immunol , vol.16 , pp. 1181-1188
    • Zhong, X.1    Bai, C.2    Gao, W.3    Strom, T.B.4    Rothstein, T.L.5
  • 32
    • 0037438490 scopus 로고    scopus 로고
    • Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: Attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses
    • Bennett F, Luxenberg D, Ling V, Wang IM, Marquette K, Lowe D, et al. Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. J Immunol 2003;170:711-8.
    • (2003) J Immunol , vol.170 , pp. 711-718
    • Bennett, F.1    Luxenberg, D.2    Ling, V.3    Wang, I.M.4    Marquette, K.5    Lowe, D.6
  • 33
    • 4444381493 scopus 로고    scopus 로고
    • Alarcon-Riquelme ME. Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus. Arthritis Res Ther 2004;6:169-73.
    • Alarcon-Riquelme ME. Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus. Arthritis Res Ther 2004;6:169-73.
  • 34
    • 0345659216 scopus 로고    scopus 로고
    • A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis
    • Helms C, Cao L, Krueger JG, Wijsman EM, Chamian F, Gordon D, et al. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nat Genet 2003;35:349-56.
    • (2003) Nat Genet , vol.35 , pp. 349-356
    • Helms, C.1    Cao, L.2    Krueger, J.G.3    Wijsman, E.M.4    Chamian, F.5    Gordon, D.6
  • 35
    • 0344364566 scopus 로고    scopus 로고
    • An intronic SNP in RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
    • Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, et al. An intronic SNP in RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 2003;35:341-8.
    • (2003) Nat Genet , vol.35 , pp. 341-348
    • Tokuhiro, S.1    Yamada, R.2    Chang, X.3    Suzuki, A.4    Kochi, Y.5    Sawada, T.6
  • 36
    • 0032532273 scopus 로고    scopus 로고
    • Initiation of the autologous mixed lymphocyte reaction requires the expression of costimulatory molecules B7-1 and B7-2 on human peripheral blood dendritic cells
    • Scheinecker C, Machold KP, Majdic O, Hoecker P, Knapp W, Smolen JS. Initiation of the autologous mixed lymphocyte reaction requires the expression of costimulatory molecules B7-1 and B7-2 on human peripheral blood dendritic cells. J Immunol 1998;161:3966-73.
    • (1998) J Immunol , vol.161 , pp. 3966-3973
    • Scheinecker, C.1    Machold, K.P.2    Majdic, O.3    Hoecker, P.4    Knapp, W.5    Smolen, J.S.6
  • 37
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-34.
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3    Bourque, K.4    Chernova, T.5    Nishimura, H.6
  • 38
    • 0033005853 scopus 로고    scopus 로고
    • Serum IL-6, TNFα, p55 srTNFα, p75srTNFα, srIL-2α levels and disease activity in systemic lupus erythematosus
    • Davas EM, Tsirogianni A, Kappou I, Karamitsos D, Economidou I, Dantis PC. Serum IL-6, TNFα, p55 srTNFα, p75srTNFα, srIL-2α levels and disease activity in systemic lupus erythematosus. Clin Rheumatol 1999;18:17-22.
    • (1999) Clin Rheumatol , vol.18 , pp. 17-22
    • Davas, E.M.1    Tsirogianni, A.2    Kappou, I.3    Karamitsos, D.4    Economidou, I.5    Dantis, P.C.6
  • 40
    • 0037214074 scopus 로고    scopus 로고
    • Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcγRII dependent mechanism: Implications for a possible vicious cycle maintaining B cell hyperactivity in SLE
    • Ronnelid J, Tejde A, Mathsson L, Nilsson-Ekdahl K, Nilsson B. Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcγRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE. Ann Rheum Dis 2003;62:37-42.
    • (2003) Ann Rheum Dis , vol.62 , pp. 37-42
    • Ronnelid, J.1    Tejde, A.2    Mathsson, L.3    Nilsson-Ekdahl, K.4    Nilsson, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.